| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.103566 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0696127 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0619375 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0490858 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0489801 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0463247 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0454024 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0433794 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0427087 |
| PRKCA | protein kinase C, alpha | 0.0426054 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0406157 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0394338 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0393781 |
| LDHA | lactate dehydrogenase A | 0.0390762 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.03825 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0365055 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0353722 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.035038 |
| PKM | pyruvate kinase, muscle | 0.0349914 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0341276 |
| DTNA | dystrobrevin, alpha | 0.0341189 |
| YEATS2 | YEATS domain containing 2 | 0.0339838 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0334359 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.033367 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0329356 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0328352 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0318555 |
| SNX14 | sorting nexin 14 | 0.0318245 |
| PRR16 | proline rich 16 | 0.031635 |
| CAPRIN2 | caprin family member 2 | 0.0308433 |
| HELZ | helicase with zinc finger | 0.030597 |
| ZNF609 | zinc finger protein 609 | 0.0303305 |
| CDCP1 | CUB domain containing protein 1 | 0.0302184 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0300325 |
| NUP153 | nucleoporin 153kDa | 0.0300269 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.030009 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0299826 |
| SVIL | supervillin | 0.0295485 |
| MED13 | mediator complex subunit 13 | 0.0295287 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0294997 |
| CCDC50 | coiled-coil domain containing 50 | 0.0293363 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0289787 |
| CFH | complement factor H | 0.0288797 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0288386 |
| NGLY1 | N-glycanase 1 | 0.0285725 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0285501 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.028419 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0283298 |
| FLNB | filamin B, beta | 0.0283037 |
| HMGA2 | high mobility group AT-hook 2 | 0.0281985 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0280821 |
| COL5A1 | collagen, type V, alpha 1 | 0.0277363 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0274653 |
| SEPTIN9 | septin 9 | 0.027269 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0270339 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0268783 |
| SRPK2 | SRSF protein kinase 2 | 0.0265275 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0263601 |
| TAOK3 | TAO kinase 3 | 0.0260161 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0260068 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0257444 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0256459 |
| TXNIP | thioredoxin interacting protein | 0.0255907 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.025503 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0254545 |
| PARD3 | par-3 family cell polarity regulator | 0.0253062 |
| PTK2 | protein tyrosine kinase 2 | 0.0252452 |
| FAM222B | family with sequence similarity 222, member B | 0.0248518 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0247332 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0243639 |
| XPO6 | exportin 6 | 0.0242005 |
| HCFC1 | host cell factor C1 | 0.0241478 |
| RNF213 | ring finger protein 213 | 0.023984 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0239653 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0238673 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0238559 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0237664 |
| AHNAK | AHNAK nucleoprotein | 0.023716 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0236239 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0235951 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.023363 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0233594 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.023184 |
| KIAA1958 | KIAA1958 | 0.0230817 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0230243 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0229316 |
| ATXN1 | ataxin 1 | 0.0227072 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0226199 |
| JAK1 | Janus kinase 1 | 0.0222486 |
| ACTN4 | actinin, alpha 4 | 0.0220782 |
| PCED1B | PC-esterase domain containing 1B | 0.0218568 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV | 0.0218278 |
| KLHL24 | kelch-like family member 24 | 0.0217727 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.021684 |
| TJP1 | tight junction protein 1 | 0.0216651 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0216582 |
| DENND1A | DENN/MADD domain containing 1A | 0.0216197 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0214404 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0214035 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0213962 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.175388 |
| YBX3 | Y box binding protein 3 | -0.0821683 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0719808 |
| VIM | vimentin | -0.0719061 |
| MT2A | metallothionein 2A | -0.070901 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0707217 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0599334 |
| RPL23 | ribosomal protein L23 | -0.0594497 |
| RPLP1 | ribosomal protein, large, P1 | -0.0585016 |
| RPS6 | ribosomal protein S6 | -0.057675 |
| RPS8 | ribosomal protein S8 | -0.0566397 |
| DEK | DEK proto-oncogene | -0.0534505 |
| RPL12 | ribosomal protein L12 | -0.0497386 |
| RPL32 | ribosomal protein L32 | -0.0490113 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0488479 |
| RPL11 | ribosomal protein L11 | -0.0484823 |
| ACTG1 | actin gamma 1 | -0.0479412 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0474986 |
| OSMR | oncostatin M receptor | -0.0474778 |
| RPL9 | ribosomal protein L9 | -0.0469161 |
| RPL37A | ribosomal protein L37a | -0.0450691 |
| B2M | beta-2-microglobulin | -0.0435894 |
| TMSB10 | thymosin beta 10 | -0.0428756 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.041691 |
| RPL26 | ribosomal protein L26 | -0.0411171 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0399392 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0396003 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0389333 |
| RPL36 | ribosomal protein L36 | -0.0388086 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0384339 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0381045 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0380296 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.037838 |
| RACK1 | receptor for activated C kinase 1 | -0.0377662 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0375634 |
| RPLP2 | ribosomal protein, large, P2 | -0.0373231 |
| RPS14 | ribosomal protein S14 | -0.0365773 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0363302 |
| TPX2 | TPX2, microtubule-associated | -0.0360825 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0359154 |
| KIAA1328 | KIAA1328 | -0.0358257 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0355533 |
| GOLGA4 | golgin A4 | -0.0353104 |
| PTMA | prothymosin, alpha | -0.0352107 |
| RPS17 | ribosomal protein S17 | -0.0347911 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0343169 |
| RPL19 | ribosomal protein L19 | -0.0340466 |
| RAD51B | RAD51 paralog B | -0.0336141 |
| CEP295 | centrosomal protein 295kDa | -0.0335639 |
| RPLP0 | ribosomal protein, large, P0 | -0.0330542 |
| RPS27A | ribosomal protein S27a | -0.0329663 |
| RPS3 | ribosomal protein S3 | -0.0328765 |
| RBM25 | RNA binding motif protein 25 | -0.0326725 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0326539 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.031734 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0305915 |
| SGO2 | shugoshin 2 | -0.0304697 |
| RPL37 | ribosomal protein L37 | -0.0295581 |
| TPM4 | tropomyosin 4 | -0.0288548 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0288477 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0286698 |
| RPL35A | ribosomal protein L35a | -0.0286626 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.028585 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0283612 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0279368 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0278737 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.027833 |
| RPS25 | ribosomal protein S25 | -0.0275909 |
| TXNRD1 | thioredoxin reductase 1 | -0.0275745 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0272299 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0271055 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0270654 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.026997 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0267643 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.02668 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0265014 |
| RPL35 | ribosomal protein L35 | -0.0263915 |
| PHIP | pleckstrin homology domain interacting protein | -0.0263412 |
| SRP54 | signal recognition particle 54kDa | -0.0262646 |
| DIAPH3 | diaphanous-related formin 3 | -0.0261891 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0260316 |
| RPL31 | ribosomal protein L31 | -0.0257087 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0256042 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0253042 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0251048 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0251026 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0249511 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0248249 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.0247886 |
| CENPF | centromere protein F, 350/400kDa | -0.024748 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0246723 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0244397 |
| MKI67 | marker of proliferation Ki-67 | -0.0244129 |
| GNAS | GNAS complex locus | -0.0242893 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0240596 |
| RPS15 | ribosomal protein S15 | -0.0239723 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0238608 |
| EXOC6B | exocyst complex component 6B | -0.0237908 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0236956 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.023654 |
