| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bisoprolol (hemifumarate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.104152 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0721177 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.06595 |
| VCL | vinculin | 0.0654752 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0636786 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.061415 |
| TMEM156 | transmembrane protein 156 | 0.0594747 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.053433 |
| FN1 | fibronectin 1 | 0.0520246 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0505898 |
| SMAD3 | SMAD family member 3 | 0.0432711 |
| SEPTIN9 | septin 9 | 0.0428117 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0390003 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0363911 |
| FLNA | filamin A, alpha | 0.0353101 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0335226 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0333399 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.03328 |
| ITGA1 | integrin, alpha 1 | 0.0324441 |
| HMGA2 | high mobility group AT-hook 2 | 0.0322617 |
| PELO | pelota homolog (Drosophila) | 0.0306059 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0292777 |
| MAP1B | microtubule-associated protein 1B | 0.029049 |
| GRB10 | growth factor receptor-bound protein 10 | 0.028294 |
| TOP1 | topoisomerase (DNA) I | 0.0280776 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0279796 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.027941 |
| FAT1 | FAT atypical cadherin 1 | 0.027705 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0273451 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0257601 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.025566 |
| OSMR | oncostatin M receptor | 0.0245308 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0244045 |
| MLPH | melanophilin | 0.0242952 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0242605 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0238763 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0238481 |
| WDR1 | WD repeat domain 1 | 0.0237431 |
| PTK2 | protein tyrosine kinase 2 | 0.0236815 |
| NTN4 | netrin 4 | 0.0228277 |
| EGR1 | early growth response 1 | 0.0225336 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0223447 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0221881 |
| HPCAL1 | hippocalcin-like 1 | 0.0219445 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0217255 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0213516 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0212954 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0211052 |
| SVIL | supervillin | 0.0210907 |
| HSPA8 | heat shock 70kDa protein 8 | 0.021063 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0208606 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0206347 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0206168 |
| AHNAK | AHNAK nucleoprotein | 0.0205078 |
| CCND1 | cyclin D1 | 0.0203927 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0200985 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0200444 |
| ACTN4 | actinin, alpha 4 | 0.0200136 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0198047 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0194373 |
| RIGI | RNA sensor RIG-I | 0.0193693 |
| RNF213 | ring finger protein 213 | 0.0191085 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0189839 |
| KLHL5 | kelch-like family member 5 | 0.0189667 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0188446 |
| IL6ST | interleukin 6 signal transducer | 0.0186174 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0185838 |
| DUSP6 | dual specificity phosphatase 6 | 0.018518 |
| S100A10 | S100 calcium binding protein A10 | 0.0182747 |
| RAD51B | RAD51 paralog B | 0.0182159 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0178655 |
| ITGB5 | integrin, beta 5 | 0.0175692 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0175419 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0174258 |
| USP12 | ubiquitin specific peptidase 12 | 0.0173414 |
| CAB39 | calcium binding protein 39 | 0.0171786 |
| IFI44L | interferon-induced protein 44-like | 0.0170619 |
| ATXN1 | ataxin 1 | 0.0169064 |
| TNNC1 | troponin C type 1 (slow) | 0.0167352 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0166359 |
| STK24 | serine/threonine kinase 24 | 0.0164106 |
| CORO1C | coronin, actin binding protein, 1C | 0.0162893 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0161556 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0161067 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0159503 |
| VCAN | versican | 0.01592 |
| ACTN1 | actinin, alpha 1 | 0.0158179 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0157935 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0157036 |
| FHIT | fragile histidine triad | 0.0156977 |
| SSH1 | slingshot protein phosphatase 1 | 0.0156452 |
| H1-0 | H1.0 linker histone | 0.0156358 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0149153 |
| TENM4 | teneurin transmembrane protein 4 | 0.0148706 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0148414 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.0148343 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0147327 |
| NRG1 | neuregulin 1 | 0.0146804 |
| DNMBP | dynamin binding protein | 0.0145181 |
| RUNX1 | runt-related transcription factor 1 | 0.0145178 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.131719 |
| PTMA | prothymosin, alpha | -0.128124 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0979151 |
| CANX | calnexin | -0.0912557 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0902998 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0859051 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0857439 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0857285 |
| FTL | ferritin, light polypeptide | -0.0800232 |
| TMSB10 | thymosin beta 10 | -0.0670476 |
| NDRG1 | N-myc downstream regulated 1 | -0.066921 |
| GOLGA4 | golgin A4 | -0.0648386 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0643257 |
| MT2A | metallothionein 2A | -0.0639216 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0617487 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0616609 |
| TPR | translocated promoter region, nuclear basket protein | -0.0611624 |
| COPA | coatomer protein complex, subunit alpha | -0.0599119 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0590628 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0582923 |
| RPS6 | ribosomal protein S6 | -0.0575102 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0572891 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0563237 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0551113 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0547922 |
| VIM | vimentin | -0.0522773 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0520552 |
| CALR | calreticulin | -0.0509137 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0504526 |
| SUCO | SUN domain containing ossification factor | -0.0496569 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0493259 |
| TXNIP | thioredoxin interacting protein | -0.048285 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0480189 |
| B2M | beta-2-microglobulin | -0.0464155 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0434798 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0403344 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.040268 |
| CD109 | CD109 molecule | -0.0401123 |
| RPS3 | ribosomal protein S3 | -0.0397917 |
| PRRC2C | proline-rich coiled-coil 2C | -0.03949 |
| RBM25 | RNA binding motif protein 25 | -0.0390322 |
| RPL31 | ribosomal protein L31 | -0.0382378 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0382163 |
| MTDH | metadherin | -0.0380818 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0367701 |
| COG5 | component of oligomeric golgi complex 5 | -0.0361177 |
| CEP350 | centrosomal protein 350kDa | -0.0349311 |
| HLA-B | major histocompatibility complex, class I, B | -0.0349058 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0345724 |
| LMNA | lamin A/C | -0.034133 |
| NKTR | natural killer cell triggering receptor | -0.033261 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0331531 |
| TMEM165 | transmembrane protein 165 | -0.0325254 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.032147 |
| GLIS3 | GLIS family zinc finger 3 | -0.0320203 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0319541 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0318351 |
| RPS19 | ribosomal protein S19 | -0.0313423 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0309116 |
| S100A6 | S100 calcium binding protein A6 | -0.0305178 |
| RAI14 | retinoic acid induced 14 | -0.0300099 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0299672 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0299047 |
| VEGFA | vascular endothelial growth factor A | -0.0297108 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0293095 |
| NOP58 | NOP58 ribonucleoprotein | -0.0292486 |
| RPS27 | ribosomal protein S27 | -0.0289304 |
| RPL35A | ribosomal protein L35a | -0.0287416 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0284672 |
| HMGB3 | high mobility group box 3 | -0.0283716 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0275872 |
| SRP54 | signal recognition particle 54kDa | -0.0275148 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0274656 |
| RPL37A | ribosomal protein L37a | -0.0272704 |
| RPL9 | ribosomal protein L9 | -0.0270125 |
| RPL26 | ribosomal protein L26 | -0.0269989 |
| RPL11 | ribosomal protein L11 | -0.026971 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0267586 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0267264 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0265711 |
| USP34 | ubiquitin specific peptidase 34 | -0.0265514 |
| HDGF | hepatoma-derived growth factor | -0.0264675 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0264205 |
| RACK1 | receptor for activated C kinase 1 | -0.0263438 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0263412 |
| COG6 | component of oligomeric golgi complex 6 | -0.0263149 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0263074 |
| RPS8 | ribosomal protein S8 | -0.0262202 |
| TMF1 | TATA element modulatory factor 1 | -0.02609 |
| INSIG2 | insulin induced gene 2 | -0.0260461 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0259783 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0256259 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0255772 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0255141 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.025481 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0253736 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0253294 |
| CALU | calumenin | -0.0253101 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.025237 |
| RPS12 | ribosomal protein S12 | -0.025186 |
