| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bisoprolol (hemifumarate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bisoprolol (hemifumarate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FHIT | fragile histidine triad | 0.0767366 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0727285 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0588511 |
| RAD51B | RAD51 paralog B | 0.0510156 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.047882 |
| LAMA4 | laminin, alpha 4 | 0.0420705 |
| HMGA2 | high mobility group AT-hook 2 | 0.0410654 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.040332 |
| EGR1 | early growth response 1 | 0.0377859 |
| EHBP1 | EH domain binding protein 1 | 0.0344809 |
| EPHA2 | EPH receptor A2 | 0.033498 |
| RCOR1 | REST corepressor 1 | 0.0330293 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0321335 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0303284 |
| EXOC4 | exocyst complex component 4 | 0.0291866 |
| FERMT1 | fermitin family member 1 | 0.0270782 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0270478 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0267928 |
| DSPP | dentin sialophosphoprotein | 0.0267842 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0265178 |
| SNX9 | sorting nexin 9 | 0.0263721 |
| BCL2L1 | BCL2-like 1 | 0.0252184 |
| EZR | ezrin | 0.0251084 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0250132 |
| CD9 | CD9 molecule | 0.0249334 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.02492 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0243807 |
| HDAC2 | histone deacetylase 2 | 0.0239282 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.023749 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | 0.023702 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0235622 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0232862 |
| PHF14 | PHD finger protein 14 | 0.0231931 |
| FLOT1 | flotillin 1 | 0.0230613 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0225838 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0225723 |
| ZNRF3 | zinc and ring finger 3 | 0.0225556 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0218294 |
| GPHN | gephyrin | 0.0215447 |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.0214432 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0213458 |
| ITGB4 | integrin, beta 4 | 0.0212472 |
| VMP1 | vacuole membrane protein 1 | 0.021102 |
| SEPTIN9 | septin 9 | 0.0208153 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0207478 |
| TUBA1B | tubulin, alpha 1b | 0.0203489 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0201765 |
| PARD3 | par-3 family cell polarity regulator | 0.0195956 |
| BPTF | bromodomain PHD finger transcription factor | 0.019194 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0187523 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0186939 |
| OXR1 | oxidation resistance 1 | 0.018677 |
| FOXP1 | forkhead box P1 | 0.0183588 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0183497 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0182129 |
| CUX1 | cut-like homeobox 1 | 0.0180255 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.017934 |
| KLK10 | kallikrein-related peptidase 10 | 0.017655 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0175714 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0171781 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0170665 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0168701 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0167802 |
| CCND1 | cyclin D1 | 0.0167332 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0165499 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.016488 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0164206 |
| POTEF | POTE ankyrin domain family, member F | 0.016318 |
| WWC1 | WW and C2 domain containing 1 | 0.0161775 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0161722 |
| AK1 | adenylate kinase 1 | 0.0161161 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0159039 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0158621 |
| NHSL1 | NHS-like 1 | 0.0155236 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0154879 |
| EREG | epiregulin | 0.0154383 |
| FOSL1 | FOS-like antigen 1 | 0.0154058 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.0153614 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0152209 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0150544 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0148903 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0147601 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0147593 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0147225 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0147041 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0143065 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0142939 |
| CEP83 | centrosomal protein 83kDa | 0.0140955 |
| TNS3 | tensin 3 | 0.0140362 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0139213 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.0138673 |
| EDAR | ectodysplasin A receptor | 0.0137452 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0136122 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0135811 |
| CALR | calreticulin | 0.0135038 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0134032 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0133777 |
| FAM120A | family with sequence similarity 120A | 0.0133333 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0132506 |
| DIAPH3 | diaphanous-related formin 3 | 0.0131696 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0972495 |
| PTMA | prothymosin, alpha | -0.0949135 |
| TMSB10 | thymosin beta 10 | -0.0940356 |
| IER3 | immediate early response 3 | -0.0825527 |
| RPLP1 | ribosomal protein, large, P1 | -0.0755912 |
| RPS6 | ribosomal protein S6 | -0.0623543 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0587793 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.057871 |
| RPS19 | ribosomal protein S19 | -0.0565973 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0552032 |
| RPL35A | ribosomal protein L35a | -0.0551137 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0522049 |
| NDRG1 | N-myc downstream regulated 1 | -0.049778 |
| TOP1 | topoisomerase (DNA) I | -0.0483434 |
| LMO7 | LIM domain 7 | -0.0483417 |
| RPS8 | ribosomal protein S8 | -0.0483098 |
| RPL26 | ribosomal protein L26 | -0.0461085 |
| ANXA1 | annexin A1 | -0.0428912 |
| RPL34 | ribosomal protein L34 | -0.0426276 |
| RPL37A | ribosomal protein L37a | -0.0421953 |
| RPL9 | ribosomal protein L9 | -0.0419411 |
| RPL36 | ribosomal protein L36 | -0.0402206 |
| RPL23 | ribosomal protein L23 | -0.0400431 |
| RPL12 | ribosomal protein L12 | -0.0393508 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0384238 |
| RPS12 | ribosomal protein S12 | -0.0382713 |
| AREG | amphiregulin | -0.0379013 |
| MT2A | metallothionein 2A | -0.0367057 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.036294 |
| FTL | ferritin, light polypeptide | -0.0350843 |
| RPL11 | ribosomal protein L11 | -0.0343306 |
| RPS3 | ribosomal protein S3 | -0.034111 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.033258 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0328087 |
| RPS4X | ribosomal protein S4, X-linked | -0.0313527 |
| RPS21 | ribosomal protein S21 | -0.0313416 |
| GOLGA4 | golgin A4 | -0.0312161 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0304283 |
| GDF15 | growth differentiation factor 15 | -0.0299281 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0294697 |
| RPL13A | ribosomal protein L13a | -0.0293922 |
| FAM3C | family with sequence similarity 3, member C | -0.0278487 |
| S100A11 | S100 calcium binding protein A11 | -0.0276322 |
| RPL27 | ribosomal protein L27 | -0.0260835 |
| TXNRD1 | thioredoxin reductase 1 | -0.0254135 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0247541 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0238664 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0232792 |
| RAB10 | RAB10, member RAS oncogene family | -0.0228631 |
| RPL7 | ribosomal protein L7 | -0.0226882 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0223667 |
| LDHA | lactate dehydrogenase A | -0.0223318 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0222266 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0212549 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0211619 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.021109 |
| RPL31 | ribosomal protein L31 | -0.020893 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0208319 |
| SQSTM1 | sequestosome 1 | -0.0207291 |
| RPLP0 | ribosomal protein, large, P0 | -0.0206065 |
| RPS27A | ribosomal protein S27a | -0.0205911 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.020551 |
| RPS28 | ribosomal protein S28 | -0.0205396 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0205328 |
| RPL5 | ribosomal protein L5 | -0.0201163 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0199425 |
| RPS27 | ribosomal protein S27 | -0.0198418 |
| RPL19 | ribosomal protein L19 | -0.0197702 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0197354 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0197344 |
| ATF4 | activating transcription factor 4 | -0.0196842 |
| ACTG1 | actin gamma 1 | -0.0196712 |
| PKM | pyruvate kinase, muscle | -0.0196696 |
| CALU | calumenin | -0.0196508 |
| RNF43 | ring finger protein 43 | -0.0195704 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0194687 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0193715 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.01932 |
| YBX3 | Y box binding protein 3 | -0.0190484 |
| RPS17 | ribosomal protein S17 | -0.01882 |
| ARRDC3 | arrestin domain containing 3 | -0.0185774 |
| RRBP1 | ribosome binding protein 1 | -0.0184331 |
| RACK1 | receptor for activated C kinase 1 | -0.0181041 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0177274 |
| RPL35 | ribosomal protein L35 | -0.0176876 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0176718 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0175119 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0175039 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0174444 |
| PERP | PERP, TP53 apoptosis effector | -0.0173025 |
| RPS11 | ribosomal protein S11 | -0.0172914 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0172037 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0171867 |
| PGK1 | phosphoglycerate kinase 1 | -0.0171719 |
| NBAS | neuroblastoma amplified sequence | -0.0168249 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0167477 |
| RPS24 | ribosomal protein S24 | -0.016661 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0166423 |
| OGA | O-GlcNAcase | -0.0166369 |
| LAMB3 | laminin, beta 3 | -0.0164947 |
