| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/16201612 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in Bombesin relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SBNO2 | strawberry notch homolog 2 (Drosophila) | 3.5 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 2.74 |
| FBRSL1 | fibrosin-like 1 | 2.21 |
| DMD | dystrophin | 1.26 |
| NRXN3 | neurexin 3 | 1.2 |
| TRAK2 | trafficking protein, kinesin binding 2 | 0.67 |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F | 0.63 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.58 |
| PEX19 | peroxisomal biogenesis factor 19 | 0.57 |
| ZNF624 | zinc finger protein 624 | 0.56 |
| R3HDM2 | R3H domain containing 2 | 0.53 |
| COPRS | coordinator of PRMT5, differentiation stimulator | 0.52 |
| ZNF189 | zinc finger protein 189 | 0.52 |
| MIB2 | mindbomb E3 ubiquitin protein ligase 2 | 0.46 |
| POLE4 | polymerase (DNA-directed), epsilon 4, accessory subunit | 0.46 |
| THBS2 | thrombospondin 2 | 0.44 |
| RGN | regucalcin | 0.43 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 0.43 |
| MORC4 | MORC family CW-type zinc finger 4 | 0.42 |
| DOLK | dolichol kinase | 0.41 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.41 |
| RNF166 | ring finger protein 166 | 0.41 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.41 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.39 |
| HAUS7 | HAUS augmin-like complex, subunit 7 | 0.38 |
| UBL7 | ubiquitin-like 7 | 0.37 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.37 |
| PEX7 | peroxisomal biogenesis factor 7 | 0.36 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.36 |
| RNF111 | ring finger protein 111 | 0.35 |
| ADK | adenosine kinase | 0.34 |
| LRRC8B | leucine rich repeat containing 8 family, member B | 0.34 |
| AURKAIP1 | aurora kinase A interacting protein 1 | 0.33 |
| DUSP7 | dual specificity phosphatase 7 | 0.33 |
| VEZF1 | vascular endothelial zinc finger 1 | 0.33 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | 0.33 |
| ZNF584 | zinc finger protein 584 | 0.33 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | 0.32 |
| PRIMPOL | primase and polymerase (DNA-directed) | 0.32 |
| BCDIN3D | BCDIN3 domain containing | 0.32 |
| TRAF5 | TNF receptor-associated factor 5 | 0.31 |
| NDRG2 | NDRG family member 2 | 0.31 |
| TTC27 | tetratricopeptide repeat domain 27 | 0.31 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.31 |
| CSNK1G3 | casein kinase 1, gamma 3 | 0.31 |
| NIN | ninein (GSK3B interacting protein) | 0.3 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.3 |
| RPE | ribulose-5-phosphate-3-epimerase | 0.3 |
| CAB39L | calcium binding protein 39-like | 0.3 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 | 0.3 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) | 0.3 |
| ZNF460 | zinc finger protein 460 | 0.3 |
| MCRIP2 | MAPK regulated corepressor interacting protein 2 | 0.29 |
| FLII | flightless I homolog (Drosophila) | 0.29 |
| AMN1 | antagonist of mitotic exit network 1 homolog (S. cerevisiae) | 0.29 |
| MLXIPL | MLX interacting protein-like | 0.29 |
| WWC2 | WW and C2 domain containing 2 | 0.29 |
| PFDN4 | prefoldin subunit 4 | 0.29 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 0.29 |
| ZNF337 | zinc finger protein 337 | 0.29 |
| PXN | paxillin | 0.29 |
| DCDC1 | doublecortin domain containing 1 | 0.28 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.28 |
| PDE5A | phosphodiesterase 5A, cGMP-specific | 0.28 |
| E2F4 | E2F transcription factor 4, p107/p130-binding | 0.28 |
| BBS2 | Bardet-Biedl syndrome 2 | 0.28 |
| KLHL20 | kelch-like family member 20 | 0.28 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 | 0.28 |
| IFT57 | intraflagellar transport 57 | 0.28 |
| UST | uronyl-2-sulfotransferase | 0.28 |
| C12ORF4 | chromosome 12 open reading frame 4 | 0.28 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.28 |
| JDP2 | Jun dimerization protein 2 | 0.27 |
| ZNF814 | zinc finger protein 814 | 0.27 |
| SPIDR | scaffolding protein involved in DNA repair | 0.27 |
| BCAS2 | breast carcinoma amplified sequence 2 | 0.27 |
| SCAND1 | SCAN domain containing 1 | 0.27 |
| DCAF12 | DDB1 and CUL4 associated factor 12 | 0.27 |
| SPRYD3 | SPRY domain containing 3 | 0.26 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.26 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.26 |
| DUOX1 | dual oxidase 1 | 0.26 |
| DESI2 | desumoylating isopeptidase 2 | 0.26 |
| ZNF160 | zinc finger protein 160 | 0.26 |
| ZNF367 | zinc finger protein 367 | 0.26 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.26 |
| SVIP | small VCP/p97-interacting protein | 0.26 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.26 |
| AP5M1 | adaptor-related protein complex 5, mu 1 subunit | 0.25 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.25 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.25 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.25 |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial | 0.25 |
| MED22 | mediator complex subunit 22 | 0.25 |
| SLC66A2 | solute carrier family 66 member 2 | 0.25 |
| MYNN | myoneurin | 0.25 |
| CNTNAP1 | contactin associated protein 1 | 0.25 |
| CUL7 | cullin 7 | 0.25 |
| UBQLN1 | ubiquilin 1 | 0.25 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.24 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TSPAN3 | tetraspanin 3 | -0.87 |
| PIP | prolactin-induced protein | -0.72 |
| SYTL1 | synaptotagmin-like 1 | -0.67 |
| SARDH | sarcosine dehydrogenase | -0.53 |
| NRP1 | neuropilin 1 | -0.49 |
| ZNF275 | zinc finger protein 275 | -0.49 |
| SLC6A17 | solute carrier family 6 (neutral amino acid transporter), member 17 | -0.49 |
| CD63 | CD63 molecule | -0.48 |
| PAH | phenylalanine hydroxylase | -0.45 |
| BBS4 | Bardet-Biedl syndrome 4 | -0.44 |
| TMEM200A | transmembrane protein 200A | -0.43 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.41 |
| MSL3P1 | male-specific lethal 3 homolog (Drosophila) pseudogene 1 | -0.41 |
| RNF13 | ring finger protein 13 | -0.41 |
| HBA1 | hemoglobin, alpha 1 | -0.4 |
| GMCL2 | germ cell-less 2, spermatogenesis associated | -0.4 |
| SGSM1 | small G protein signaling modulator 1 | -0.4 |
| RYK | receptor-like tyrosine kinase | -0.4 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.39 |
| ZNF696 | zinc finger protein 696 | -0.38 |
| NOTCH3 | notch 3 | -0.38 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.38 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 | -0.38 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | -0.37 |
| RNF149 | ring finger protein 149 | -0.37 |
| ATE1 | arginyltransferase 1 | -0.37 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 | -0.36 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | -0.36 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.36 |
| RBM47 | RNA binding motif protein 47 | -0.36 |
| TSPAN33 | tetraspanin 33 | -0.34 |
| CCDC158 | coiled-coil domain containing 158 | -0.34 |
| DPY19L2 | dpy-19-like 2 (C. elegans) | -0.33 |
| NEU3 | sialidase 3 (membrane sialidase) | -0.33 |
| MED8 | mediator complex subunit 8 | -0.32 |
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1 | -0.32 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.31 |
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 | -0.31 |
| GUCD1 | guanylyl cyclase domain containing 1 | -0.3 |
| PES1 | pescadillo ribosomal biogenesis factor 1 | -0.3 |
| TP73 | tumor protein p73 | -0.29 |
| ACTN4 | actinin, alpha 4 | -0.29 |
| NCOA4 | nuclear receptor coactivator 4 | -0.29 |
| MFSD6 | major facilitator superfamily domain containing 6 | -0.29 |
| SDF2 | stromal cell-derived factor 2 | -0.28 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -0.28 |
| BAK1 | BCL2-antagonist/killer 1 | -0.28 |
| ALKBH5 | AlkB family member 5, RNA demethylase | -0.28 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.27 |
| FCHO1 | FCH domain only 1 | -0.27 |
| CLCN7 | chloride channel, voltage-sensitive 7 | -0.27 |
| ZSCAN21 | zinc finger and SCAN domain containing 21 | -0.27 |
| ZNF787 | zinc finger protein 787 | -0.27 |
| SMAP1 | small ArfGAP 1 | -0.27 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.27 |
| BAIAP2 | BAI1-associated protein 2 | -0.27 |
| APOB | apolipoprotein B | -0.27 |
| SERAC1 | serine active site containing 1 | -0.26 |
| RNF167 | ring finger protein 167 | -0.26 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.26 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.26 |
| CST6 | cystatin E/M | -0.26 |
| FAN1 | FANCD2/FANCI-associated nuclease 1 | -0.26 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.25 |
| HEMK1 | HemK methyltransferase family member 1 | -0.25 |
| GLMP | glycosylated lysosomal membrane protein | -0.25 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 | -0.25 |
| TMEM64 | transmembrane protein 64 | -0.25 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | -0.25 |
| DCLK2 | doublecortin-like kinase 2 | -0.24 |
| PPCDC | phosphopantothenoylcysteine decarboxylase | -0.24 |
| YAF2 | YY1 associated factor 2 | -0.24 |
| ZNF623 | zinc finger protein 623 | -0.24 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.24 |
| PLPP2 | phospholipid phosphatase 2 | -0.24 |
| S100A14 | S100 calcium binding protein A14 | -0.24 |
| ZDHHC8 | zinc finger, DHHC-type containing 8 | -0.24 |
| ZBTB44 | zinc finger and BTB domain containing 44 | -0.24 |
| TMSB10 | thymosin beta 10 | -0.24 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 | -0.23 |
| PTRHD1 | peptidyl-tRNA hydrolase domain containing 1 | -0.23 |
| PIGX | phosphatidylinositol glycan anchor biosynthesis, class X | -0.23 |
| ZNF526 | zinc finger protein 526 | -0.23 |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 | -0.23 |
| CEP63 | centrosomal protein 63kDa | -0.23 |
| PTK6 | protein tyrosine kinase 6 | -0.23 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -0.23 |
| CNTRL | centriolin | -0.23 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.22 |
| TNIP2 | TNFAIP3 interacting protein 2 | -0.22 |
| ZNF503 | zinc finger protein 503 | -0.22 |
| FAM8A1 | family with sequence similarity 8, member A1 | -0.21 |
| PLK4 | polo-like kinase 4 | -0.21 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.21 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.21 |
| ORMDL1 | ORMDL sphingolipid biosynthesis regulator 1 | -0.21 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase | -0.21 |
| RNF145 | ring finger protein 145 | -0.21 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | -0.21 |
| B4GALT3 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 | -0.21 |
