| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bortezomib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bortezomib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.268019 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.1206 |
| VCL | vinculin | 0.0828571 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.077028 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0767909 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0722949 |
| NDRG1 | N-myc downstream regulated 1 | 0.0707197 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0674772 |
| SEPTIN9 | septin 9 | 0.066712 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0638908 |
| EXT1 | exostosin glycosyltransferase 1 | 0.059606 |
| B2M | beta-2-microglobulin | 0.0594152 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0589005 |
| RPL23 | ribosomal protein L23 | 0.0552765 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0546634 |
| MSI2 | musashi RNA-binding protein 2 | 0.0545124 |
| PTMA | prothymosin, alpha | 0.0537051 |
| MEF2A | myocyte enhancer factor 2A | 0.0524791 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0521778 |
| SMAD3 | SMAD family member 3 | 0.0517749 |
| FN1 | fibronectin 1 | 0.0512022 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0507206 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0494082 |
| ATXN1 | ataxin 1 | 0.0493861 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0488784 |
| RPS12 | ribosomal protein S12 | 0.0487064 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0485949 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0484972 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0482799 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0472808 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0468635 |
| DTNA | dystrobrevin, alpha | 0.0468056 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0467885 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0465488 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0461604 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0451178 |
| MCL1 | myeloid cell leukemia 1 | 0.0435653 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0426008 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0423038 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0412889 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0403929 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0403475 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0391655 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0385452 |
| CUX1 | cut-like homeobox 1 | 0.0380353 |
| RPL37A | ribosomal protein L37a | 0.037956 |
| FAM13A | family with sequence similarity 13, member A | 0.0365167 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0361032 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0360742 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0360636 |
| CCDC88A | coiled-coil domain containing 88A | 0.0357801 |
| RPLP1 | ribosomal protein, large, P1 | 0.0357606 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0356689 |
| PLAT | plasminogen activator, tissue | 0.0356431 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.035452 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0354323 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0353488 |
| HSPA1B | heat shock 70kDa protein 1B | 0.0352773 |
| RPL9 | ribosomal protein L9 | 0.034638 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0342263 |
| EGFR | epidermal growth factor receptor | 0.0340074 |
| NFIB | nuclear factor I/B | 0.0334466 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0332273 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0330927 |
| HELZ | helicase with zinc finger | 0.0330659 |
| VEGFA | vascular endothelial growth factor A | 0.0326781 |
| PDE8A | phosphodiesterase 8A | 0.0325733 |
| INTS6 | integrator complex subunit 6 | 0.032174 |
| RACK1 | receptor for activated C kinase 1 | 0.0318284 |
| CDH13 | cadherin 13 | 0.0315039 |
| SIK3 | SIK family kinase 3 | 0.0310351 |
| CENPF | centromere protein F, 350/400kDa | 0.0308815 |
| TPM1 | tropomyosin 1 (alpha) | 0.0308241 |
| ZNF609 | zinc finger protein 609 | 0.0304794 |
| RPS3 | ribosomal protein S3 | 0.0303048 |
| PCBP2 | poly(rC) binding protein 2 | 0.030276 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0300862 |
| ASPH | aspartate beta-hydroxylase | 0.0293949 |
| TPR | translocated promoter region, nuclear basket protein | 0.0291436 |
| GSE1 | Gse1 coiled-coil protein | 0.0291094 |
| FUS | FUS RNA binding protein | 0.0289721 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0285002 |
| TMSB10 | thymosin beta 10 | 0.0284124 |
| HMGA2 | high mobility group AT-hook 2 | 0.0283992 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0283965 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0283174 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0281277 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0279781 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0278247 |
| RPL7 | ribosomal protein L7 | 0.0277516 |
| SQSTM1 | sequestosome 1 | 0.0277053 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0275696 |
| EZR | ezrin | 0.0275545 |
| CALD1 | caldesmon 1 | 0.0275336 |
| HM13 | histocompatibility (minor) 13 | 0.0273732 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0272078 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0271471 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0269165 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0267063 |
| RPL27 | ribosomal protein L27 | 0.026604 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.142034 |
| SYT1 | synaptotagmin I | -0.140637 |
| IGF2 | insulin-like growth factor 2 | -0.109174 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.100393 |
| MAP1B | microtubule-associated protein 1B | -0.0919102 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0845829 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0689202 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0630537 |
| FMN1 | formin 1 | -0.0565192 |
| KLHL13 | kelch-like family member 13 | -0.0551504 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0543114 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0509041 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0460472 |
| MEIS2 | Meis homeobox 2 | -0.0458709 |
| AOPEP | aminopeptidase O (putative) | -0.0445357 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0429228 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0428315 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0425625 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0421254 |
| ANGPT1 | angiopoietin 1 | -0.0420407 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0392701 |
| DST | dystonin | -0.0379936 |
| ZNF804A | zinc finger protein 804A | -0.0376626 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0374344 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0372412 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0362412 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.036108 |
| DISP1 | dispatched homolog 1 (Drosophila) | -0.0352538 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0348881 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0347143 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0342918 |
| ATRNL1 | attractin-like 1 | -0.0339039 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0330009 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0325676 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0319121 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0312018 |
| LPIN1 | lipin 1 | -0.0302519 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0298279 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0293844 |
| TMEM108 | transmembrane protein 108 | -0.028647 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0283102 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0280433 |
| HMBOX1 | homeobox containing 1 | -0.0280126 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0279535 |
| AHR | aryl hydrocarbon receptor | -0.0274016 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0272437 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0270694 |
| TRIB2 | tribbles pseudokinase 2 | -0.0269935 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.026243 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -0.025764 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.0257441 |
| COL1A1 | collagen, type I, alpha 1 | -0.025544 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0252134 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0252107 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.0249787 |
| COL3A1 | collagen, type III, alpha 1 | -0.02468 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0246788 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0243577 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.02423 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0241957 |
| GLCCI1 | glucocorticoid induced 1 | -0.0241888 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -0.0232956 |
| FTL | ferritin, light polypeptide | -0.0232637 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0231607 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0230801 |
| SH3PXD2B | SH3 and PX domains 2B | -0.0230421 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0228119 |
| NRP1 | neuropilin 1 | -0.022606 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.022417 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0223836 |
| FRMD4A | FERM domain containing 4A | -0.0221981 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0221426 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.0221361 |
| ZFHX4 | zinc finger homeobox 4 | -0.0220899 |
| SIK2 | salt-inducible kinase 2 | -0.0220064 |
| RALYL | RALY RNA binding protein-like | -0.0219134 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0218129 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0216505 |
| FAM107B | family with sequence similarity 107, member B | -0.0214332 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0213593 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0211812 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0210515 |
| PCDH9 | protocadherin 9 | -0.0210345 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.0207497 |
| GAB2 | GRB2-associated binding protein 2 | -0.0207249 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0206032 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0205209 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0204104 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | -0.0203945 |
| PRKD1 | protein kinase D1 | -0.0202756 |
| CRH | corticotropin releasing hormone | -0.0202117 |
| GPC5 | glypican 5 | -0.020087 |
| CCNL1 | cyclin L1 | -0.0199569 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0198694 |
| CCDC50 | coiled-coil domain containing 50 | -0.0197689 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0197385 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0196357 |
| ATG5 | autophagy related 5 | -0.019618 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0196151 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0194548 |
