| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bortezomib perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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96 genes differentially expressed following the Bortezomib_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.198841 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.15219 |
| LMO7 | LIM domain 7 | 0.146702 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.124912 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.122446 |
| ANXA2 | annexin A2 | 0.122168 |
| UBC | ubiquitin C | 0.118839 |
| PRRC2C | proline-rich coiled-coil 2C | 0.116923 |
| PTK2 | protein tyrosine kinase 2 | 0.115089 |
| HSPA8 | heat shock 70kDa protein 8 | 0.104147 |
| FTL | ferritin, light polypeptide | 0.103971 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0978158 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0816964 |
| VIM | vimentin | 0.0764736 |
| GPC6 | glypican 6 | 0.075482 |
| RACK1 | receptor for activated C kinase 1 | 0.065631 |
| MATR3 | matrin 3 | 0.0627913 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0603434 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0557602 |
| RPS6 | ribosomal protein S6 | 0.0556601 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0551518 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0520714 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0510489 |
| RPL35A | ribosomal protein L35a | 0.0500548 |
| FN1 | fibronectin 1 | 0.0462807 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0402758 |
| NF1 | neurofibromin 1 | 0.0372316 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0357142 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0328469 |
| PKM | pyruvate kinase, muscle | 0.0328029 |
| NDRG1 | N-myc downstream regulated 1 | 0.032125 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.0317002 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0315292 |
| RPS3 | ribosomal protein S3 | 0.0312556 |
| TMSB10 | thymosin beta 10 | 0.0294949 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0235852 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0234701 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0234474 |
| RPS12 | ribosomal protein S12 | 0.021962 |
| RPLP1 | ribosomal protein, large, P1 | 0.0215544 |
| EGFR | epidermal growth factor receptor | 0.0176166 |
| MYO1E | myosin IE | 0.0175927 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0174664 |
| RPL37A | ribosomal protein L37a | 0.0171915 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0127014 |
| RPL23 | ribosomal protein L23 | 0.0123744 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0121856 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00849291 |
| ATXN1 | ataxin 1 | 0.00452299 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.00440706 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 7.36586E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | -0.190745 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.165947 |
| PDE10A | phosphodiesterase 10A | -0.133968 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.12741 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.120921 |
| EXT1 | exostosin glycosyltransferase 1 | -0.11895 |
| CDH13 | cadherin 13 | -0.110157 |
| RORA | RAR-related orphan receptor A | -0.108872 |
| VCL | vinculin | -0.102757 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0908378 |
| ASPH | aspartate beta-hydroxylase | -0.087413 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0851363 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0721132 |
| SMYD3 | SET and MYND domain containing 3 | -0.0617415 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0585283 |
| RAD51B | RAD51 paralog B | -0.0580743 |
| SETD5 | SET domain containing 5 | -0.0580577 |
| PRKCA | protein kinase C, alpha | -0.0565955 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0558974 |
| STC1 | stanniocalcin 1 | -0.055582 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0517361 |
| HMGA2 | high mobility group AT-hook 2 | -0.0476163 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0460835 |
| DST | dystonin | -0.0397308 |
| NHSL1 | NHS-like 1 | -0.0373189 |
| FNDC3A | fibronectin type III domain containing 3A | -0.032626 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0296073 |
| LDHA | lactate dehydrogenase A | -0.0243815 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.023835 |
| PTMA | prothymosin, alpha | -0.0234031 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0221543 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0208726 |
| LAMB3 | laminin, beta 3 | -0.0148733 |
| MT2A | metallothionein 2A | -0.0132655 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0112119 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0103229 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.00978343 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00738771 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.00653442 |
| RPS8 | ribosomal protein S8 | -0.00488639 |
| TXNRD1 | thioredoxin reductase 1 | -0.00436343 |
| FLNB | filamin B, beta | -0.00420542 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.00166216 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -8.9604E-4 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -6.42886E-4 |
