| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bortezomib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bortezomib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.597093 |
| HSPA8 | heat shock 70kDa protein 8 | 0.165671 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.154108 |
| HSPA1A | heat shock 70kDa protein 1A | 0.128461 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.118598 |
| UBC | ubiquitin C | 0.109203 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0855647 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0757783 |
| VIM | vimentin | 0.0677122 |
| FTL | ferritin, light polypeptide | 0.063181 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0580673 |
| HSPA1B | heat shock 70kDa protein 1B | 0.0532902 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0512445 |
| TXNRD1 | thioredoxin reductase 1 | 0.0496055 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0397914 |
| ANXA1 | annexin A1 | 0.0349204 |
| SQSTM1 | sequestosome 1 | 0.0338605 |
| MAP1B | microtubule-associated protein 1B | 0.0333909 |
| ANKRD28 | ankyrin repeat domain 28 | 0.033043 |
| TBCA | tubulin folding cofactor A | 0.0327842 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0315083 |
| ANLN | anillin, actin binding protein | 0.0308603 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0297324 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.029702 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0296049 |
| RACK1 | receptor for activated C kinase 1 | 0.0279072 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0271651 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0270871 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0265434 |
| RPS3 | ribosomal protein S3 | 0.0261832 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0256944 |
| TPX2 | TPX2, microtubule-associated | 0.0256671 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0249977 |
| GPC6 | glypican 6 | 0.0249321 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0248358 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0246834 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0244141 |
| SGO2 | shugoshin 2 | 0.0243986 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0240043 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0230406 |
| MATR3 | matrin 3 | 0.0228282 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0227808 |
| BAG3 | BCL2-associated athanogene 3 | 0.0227644 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0227158 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0225503 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0222014 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0221055 |
| PTMA | prothymosin, alpha | 0.0214833 |
| CENPF | centromere protein F, 350/400kDa | 0.0214806 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.0214351 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0210759 |
| CD44 | CD44 molecule (Indian blood group) | 0.0210474 |
| RPL23 | ribosomal protein L23 | 0.0209203 |
| RPS12 | ribosomal protein S12 | 0.0205248 |
| EFNA5 | ephrin-A5 | 0.0204398 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0201148 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.019882 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0197312 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0196512 |
| CPNE8 | copine VIII | 0.0194475 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0194267 |
| SOD1 | superoxide dismutase 1, soluble | 0.0190565 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0189985 |
| CANX | calnexin | 0.0189089 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0188867 |
| CEP126 | centrosomal protein 126kDa | 0.0188249 |
| RPLP0 | ribosomal protein, large, P0 | 0.0187201 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0186955 |
| FNBP4 | formin binding protein 4 | 0.0186463 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0186229 |
| RBM25 | RNA binding motif protein 25 | 0.0181508 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.0179899 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0178229 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0176045 |
| TUBB | tubulin, beta class I | 0.0174756 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0173494 |
| XPO1 | exportin 1 | 0.0172848 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0171609 |
| PHIP | pleckstrin homology domain interacting protein | 0.0169914 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.016948 |
| NBAS | neuroblastoma amplified sequence | 0.016744 |
| RPL37A | ribosomal protein L37a | 0.016503 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.0164327 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | 0.0163703 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.016245 |
| RBM39 | RNA binding motif protein 39 | 0.0162251 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0162194 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.015941 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0159275 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.015895 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0158785 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0158032 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0157769 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0157642 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | 0.0157551 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.015753 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0157141 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0156914 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0156516 |
| CDK12 | cyclin-dependent kinase 12 | 0.0156506 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | -0.114844 |
| HMGA2 | high mobility group AT-hook 2 | -0.0764053 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0700141 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.061249 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0588696 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0559278 |
| AHNAK | AHNAK nucleoprotein | -0.0476528 |
| INTS6 | integrator complex subunit 6 | -0.046353 |
| PRR16 | proline rich 16 | -0.0439956 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0405674 |
| SMYD3 | SET and MYND domain containing 3 | -0.0403573 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0402971 |
| PRELID2 | PRELI domain containing 2 | -0.0377633 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0375263 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0360961 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0340847 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0334948 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.033284 |
| AEBP2 | AE binding protein 2 | -0.0327055 |
| DENND1A | DENN/MADD domain containing 1A | -0.032382 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0317339 |
| GPC5 | glypican 5 | -0.0317049 |
| PCED1B | PC-esterase domain containing 1B | -0.0308961 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0297874 |
| FMNL2 | formin-like 2 | -0.0293258 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0289578 |
| ATM | ATM serine/threonine kinase | -0.0288648 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0287993 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.028278 |
| RAD51B | RAD51 paralog B | -0.0270486 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0267282 |
| ANGPTL4 | angiopoietin-like 4 | -0.0256505 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0255268 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0254791 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0248246 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0248044 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0247078 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0246925 |
| VCL | vinculin | -0.0245972 |
| RAI14 | retinoic acid induced 14 | -0.024461 |
| UTRN | utrophin | -0.0243995 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0243945 |
| CAPRIN2 | caprin family member 2 | -0.0243878 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0243596 |
| SNX14 | sorting nexin 14 | -0.023856 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0233158 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0232353 |
| MYOF | myoferlin | -0.0230298 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0227626 |
| NABP1 | nucleic acid binding protein 1 | -0.0225674 |
| EGR1 | early growth response 1 | -0.0223707 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0221156 |
| NDRG1 | N-myc downstream regulated 1 | -0.0218803 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0216546 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.021496 |
| LDHA | lactate dehydrogenase A | -0.0211856 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0208988 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0208621 |
| CCDC88A | coiled-coil domain containing 88A | -0.0206735 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0206644 |
| PODXL | podocalyxin-like | -0.0205637 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0204675 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0204179 |
| PLEK2 | pleckstrin 2 | -0.0203985 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0203862 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.020223 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0201333 |
| SIK2 | salt-inducible kinase 2 | -0.0199741 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.019964 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0199122 |
| OSMR | oncostatin M receptor | -0.0198703 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0198 |
| PCNX4 | pecanex 4 | -0.0193607 |
| SDC4 | syndecan 4 | -0.01932 |
| SMAD3 | SMAD family member 3 | -0.0190522 |
| ABR | active BCR-related | -0.019021 |
| ZNF638 | zinc finger protein 638 | -0.0187983 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0186253 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0185942 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0185582 |
| EGFR | epidermal growth factor receptor | -0.0184858 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0180581 |
| FMN1 | formin 1 | -0.0180279 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0179833 |
| ATG7 | autophagy related 7 | -0.0177382 |
| CCND1 | cyclin D1 | -0.017683 |
| SKI | SKI proto-oncogene | -0.0176568 |
| RIGI | RNA sensor RIG-I | -0.0176278 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0174781 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0174706 |
| CCDC138 | coiled-coil domain containing 138 | -0.0174054 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0173282 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0171039 |
| USP53 | ubiquitin specific peptidase 53 | -0.0170609 |
| TVP23C-CDRT4 | TVP23C-CDRT4 readthrough | -0.0170513 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.016977 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0169648 |
| ANO6 | anoctamin 6 | -0.016873 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0168481 |
| HIPK3 | homeodomain interacting protein kinase 3 | -0.0167173 |
