| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bosentan (hydrate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bosentan (hydrate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.120835 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.101759 |
| NFIB | nuclear factor I/B | 0.0627631 |
| ITGAV | integrin, alpha V | 0.0615514 |
| CENPF | centromere protein F, 350/400kDa | 0.0582038 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0566369 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0487655 |
| DIAPH3 | diaphanous-related formin 3 | 0.0436483 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0425852 |
| MATR3 | matrin 3 | 0.0413251 |
| TXNRD1 | thioredoxin reductase 1 | 0.0409496 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0404722 |
| GPC6 | glypican 6 | 0.0386728 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0370973 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0355013 |
| RBM39 | RNA binding motif protein 39 | 0.0354982 |
| SUCO | SUN domain containing ossification factor | 0.0345522 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0344078 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0332045 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0328692 |
| MMS22L | MMS22-like, DNA repair protein | 0.0317481 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.031723 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0310711 |
| NF1 | neurofibromin 1 | 0.0310383 |
| NKTR | natural killer cell triggering receptor | 0.030893 |
| WDR43 | WD repeat domain 43 | 0.0305386 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0299559 |
| PRELID2 | PRELI domain containing 2 | 0.0298002 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0292831 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0281814 |
| ATP13A3 | ATPase type 13A3 | 0.028143 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0280928 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0278663 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0278493 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0276553 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0275729 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0271249 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0264874 |
| MSN | moesin | 0.0261928 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0261785 |
| EFNA5 | ephrin-A5 | 0.026002 |
| MEOX2 | mesenchyme homeobox 2 | 0.025889 |
| LNPK | lunapark, ER junction formation factor | 0.0258121 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0254551 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0250441 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0249841 |
| TCERG1 | transcription elongation regulator 1 | 0.0246082 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0238919 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0235778 |
| DST | dystonin | 0.0234845 |
| THOC2 | THO complex 2 | 0.0234344 |
| ETNK1 | ethanolamine kinase 1 | 0.0233848 |
| TMSB4X | thymosin beta 4, X-linked | 0.0233583 |
| POTEF | POTE ankyrin domain family, member F | 0.023296 |
| FER | fer (fps/fes related) tyrosine kinase | 0.023232 |
| SHROOM3 | shroom family member 3 | 0.0229907 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0229048 |
| SET | SET nuclear proto-oncogene | 0.0223754 |
| HOXA3 | homeobox A3 | 0.0222048 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0220142 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0220098 |
| PTEN | phosphatase and tensin homolog | 0.0219664 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0219468 |
| RSF1 | remodeling and spacing factor 1 | 0.0218999 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0218464 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | 0.0214869 |
| NRDC | nardilysin convertase | 0.0213372 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0211581 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.021098 |
| TPX2 | TPX2, microtubule-associated | 0.0209985 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0209838 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0206886 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0206777 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0204691 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0204284 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0204011 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0203626 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0203625 |
| FAM120A | family with sequence similarity 120A | 0.0203191 |
| ADNP | activity-dependent neuroprotector homeobox | 0.019967 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.019912 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.0198885 |
| RNF130 | ring finger protein 130 | 0.0198139 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0196965 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.019684 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0196765 |
| USP47 | ubiquitin specific peptidase 47 | 0.0195821 |
| RNF145 | ring finger protein 145 | 0.0195776 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0195416 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0195067 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0194217 |
| MAGT1 | magnesium transporter 1 | 0.019342 |
| RPL3 | ribosomal protein L3 | 0.0193319 |
| ATG10 | autophagy related 10 | 0.0193273 |
| HOXC6 | homeobox C6 | 0.0192226 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0190899 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.019038 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0189945 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0189435 |
| VMP1 | vacuole membrane protein 1 | 0.0187488 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.246054 |
| TMSB10 | thymosin beta 10 | -0.0735219 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0733863 |
| MT2A | metallothionein 2A | -0.073144 |
| IER3 | immediate early response 3 | -0.0730043 |
| JMJD1C | jumonji domain containing 1C | -0.0705871 |
| RPS8 | ribosomal protein S8 | -0.0667836 |
| RPS24 | ribosomal protein S24 | -0.0657063 |
| HMGA2 | high mobility group AT-hook 2 | -0.0629137 |
| MGP | matrix Gla protein | -0.0621457 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0616486 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0586963 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0583438 |
| RPL23 | ribosomal protein L23 | -0.0571274 |
| RPL35A | ribosomal protein L35a | -0.0559827 |
| PEG10 | paternally expressed 10 | -0.0555052 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.053698 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0531159 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0525465 |
| RPLP2 | ribosomal protein, large, P2 | -0.051843 |
| ERBIN | erbb2 interacting protein | -0.0516181 |
| RPS3 | ribosomal protein S3 | -0.0502328 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0469651 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0452485 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.044528 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0444871 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0437523 |
| FNIP1 | folliculin interacting protein 1 | -0.0434573 |
| ANKRD12 | ankyrin repeat domain 12 | -0.043027 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0429935 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0428063 |
| RPLP1 | ribosomal protein, large, P1 | -0.0424863 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0422451 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0419669 |
| RPS25 | ribosomal protein S25 | -0.0399347 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0386653 |
| RPL12 | ribosomal protein L12 | -0.0382983 |
| RACK1 | receptor for activated C kinase 1 | -0.0378795 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.036955 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.036091 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0358857 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0357944 |
| RPL13A | ribosomal protein L13a | -0.0352648 |
| AHNAK | AHNAK nucleoprotein | -0.0351451 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0345077 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0343081 |
| LOXL2 | lysyl oxidase-like 2 | -0.0340442 |
| RBM25 | RNA binding motif protein 25 | -0.0340197 |
| CTBP2 | C-terminal binding protein 2 | -0.0339368 |
| AHI1 | Abelson helper integration site 1 | -0.0339257 |
| ANO6 | anoctamin 6 | -0.0337981 |
| MYOF | myoferlin | -0.0333427 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0325199 |
| RPS10 | ribosomal protein S10 | -0.0322453 |
| CUX1 | cut-like homeobox 1 | -0.0321617 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0320466 |
| MEF2A | myocyte enhancer factor 2A | -0.0319604 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0318569 |
| BCOR | BCL6 corepressor | -0.0315803 |
| RHEB | Ras homolog enriched in brain | -0.0310484 |
| SFTPA2 | surfactant protein A2 | -0.0309362 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0301614 |
| TULP4 | tubby like protein 4 | -0.0301598 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.0300713 |
| RPL5 | ribosomal protein L5 | -0.0300495 |
| RPL34 | ribosomal protein L34 | -0.0298224 |
| HMGA1 | high mobility group AT-hook 1 | -0.0297691 |
| CUL1 | cullin 1 | -0.0297473 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0296335 |
| ATP11A | ATPase, class VI, type 11A | -0.0295961 |
| UVRAG | UV radiation resistance associated | -0.0295564 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0294368 |
| ACTG1 | actin gamma 1 | -0.0294339 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0292648 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.02903 |
| INTS6 | integrator complex subunit 6 | -0.0288808 |
| HBP1 | HMG-box transcription factor 1 | -0.0286637 |
| NAV1 | neuron navigator 1 | -0.028622 |
| RPL38 | ribosomal protein L38 | -0.0284046 |
| KIF13A | kinesin family member 13A | -0.0282762 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0280866 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0280234 |
| RPS4X | ribosomal protein S4, X-linked | -0.0280017 |
| SMYD3 | SET and MYND domain containing 3 | -0.0279556 |
| AK1 | adenylate kinase 1 | -0.0279154 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0276236 |
| CREM | cAMP responsive element modulator | -0.0274054 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0273555 |
| PDE10A | phosphodiesterase 10A | -0.0273449 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0271558 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0271216 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.026909 |
| PARD3 | par-3 family cell polarity regulator | -0.0268971 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | -0.0264208 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0264074 |
| FOXO3 | forkhead box O3 | -0.0263329 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0262995 |
| RPL37 | ribosomal protein L37 | -0.0261043 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0259982 |
| S100A9 | S100 calcium binding protein A9 | -0.0259812 |
