| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bosentan (hydrate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bosentan (hydrate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | 0.130278 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.127074 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.126475 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.116164 |
| APOL1 | apolipoprotein L, 1 | 0.0911829 |
| ENO1 | enolase 1, (alpha) | 0.0895499 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0889815 |
| FAM13A | family with sequence similarity 13, member A | 0.0839478 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0771317 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0751037 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0717241 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0701568 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0645422 |
| CCNY | cyclin Y | 0.0632512 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.062463 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0622149 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0600542 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0588568 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.058348 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0560409 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0559942 |
| MMP7 | matrix metallopeptidase 7 | 0.0525943 |
| RAD51B | RAD51 paralog B | 0.0514168 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.048423 |
| VEGFA | vascular endothelial growth factor A | 0.0474653 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0444731 |
| MEF2A | myocyte enhancer factor 2A | 0.044269 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0442138 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0437417 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0416832 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.040854 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0368845 |
| SMAD3 | SMAD family member 3 | 0.0357639 |
| CP | ceruloplasmin (ferroxidase) | 0.0352376 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.035106 |
| LAMB3 | laminin, beta 3 | 0.0349537 |
| ATXN1 | ataxin 1 | 0.0345119 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0341637 |
| SRP54 | signal recognition particle 54kDa | 0.0337217 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0324505 |
| ANO6 | anoctamin 6 | 0.0322773 |
| MXI1 | MAX interactor 1, dimerization protein | 0.031672 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0314272 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0311829 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0310874 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0310402 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0308116 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0302509 |
| NUP58 | nucleoporin 58 | 0.0301953 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0297304 |
| CANX | calnexin | 0.0296357 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0294243 |
| MCL1 | myeloid cell leukemia 1 | 0.029134 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0287923 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0278554 |
| STC1 | stanniocalcin 1 | 0.0272079 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0269218 |
| MTSS1 | metastasis suppressor 1 | 0.0264807 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0260972 |
| ATP13A3 | ATPase type 13A3 | 0.02606 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0259989 |
| ARRDC3 | arrestin domain containing 3 | 0.0257263 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0256825 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0256028 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.025596 |
| NAV2 | neuron navigator 2 | 0.0255222 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0253975 |
| CMIP | c-Maf inducing protein | 0.024974 |
| HMGA2 | high mobility group AT-hook 2 | 0.0248431 |
| STC2 | stanniocalcin 2 | 0.0247286 |
| TPM4 | tropomyosin 4 | 0.0246327 |
| FMNL2 | formin-like 2 | 0.0243406 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0241899 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0241887 |
| BBX | bobby sox homolog (Drosophila) | 0.0241758 |
| INSIG2 | insulin induced gene 2 | 0.0241416 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0241168 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0240505 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0240237 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0238302 |
| KRT19 | keratin 19, type I | 0.0234474 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0232141 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0229968 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0226736 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0225336 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0225256 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0223923 |
| TMF1 | TATA element modulatory factor 1 | 0.0223197 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0222377 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0220457 |
| PRELID2 | PRELI domain containing 2 | 0.0220348 |
| PLAT | plasminogen activator, tissue | 0.022026 |
| PGK1 | phosphoglycerate kinase 1 | 0.0218492 |
| ASPH | aspartate beta-hydroxylase | 0.0218234 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0218056 |
| FAM117B | family with sequence similarity 117, member B | 0.0216474 |
| TPM3 | tropomyosin 3 | 0.0215386 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0215061 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.021347 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0212905 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.22624 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.211555 |
| TMSB10 | thymosin beta 10 | -0.16637 |
| MT1X | metallothionein 1X | -0.115974 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.112951 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0903018 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0891826 |
| ACTG1 | actin gamma 1 | -0.0814527 |
| ANXA2 | annexin A2 | -0.0814525 |
| FTL | ferritin, light polypeptide | -0.076573 |
| RTN4 | reticulon 4 | -0.0764898 |
| BICC1 | BicC family RNA binding protein 1 | -0.0758343 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0710317 |
| PTMA | prothymosin, alpha | -0.0696488 |
| PLAU | plasminogen activator, urokinase | -0.0661221 |
| HLA-B | major histocompatibility complex, class I, B | -0.0642158 |
| MUC4 | mucin 4, cell surface associated | -0.0636479 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0615003 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0546081 |
| CD2AP | CD2-associated protein | -0.0522183 |
| OSMR | oncostatin M receptor | -0.0514283 |
| RPLP1 | ribosomal protein, large, P1 | -0.0503438 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0500679 |
| KLF6 | Kruppel-like factor 6 | -0.0479609 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0469069 |
| GNAS | GNAS complex locus | -0.0448466 |
| APP | amyloid beta (A4) precursor protein | -0.0428323 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0426635 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0420152 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0418343 |
| ACTN4 | actinin, alpha 4 | -0.0415872 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0407415 |
| BCL2L1 | BCL2-like 1 | -0.0396602 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0389322 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0387237 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0386393 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0383023 |
| FAM3C | family with sequence similarity 3, member C | -0.0380842 |
| MYOF | myoferlin | -0.0378174 |
| TJP1 | tight junction protein 1 | -0.037817 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0357296 |
| RBM39 | RNA binding motif protein 39 | -0.0351519 |
| RPL35A | ribosomal protein L35a | -0.0351509 |
| UBC | ubiquitin C | -0.035129 |
| B2M | beta-2-microglobulin | -0.0349245 |
| RPL19 | ribosomal protein L19 | -0.0344574 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0338693 |
| VIM | vimentin | -0.0338256 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0335446 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0335407 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0333666 |
| HLA-C | major histocompatibility complex, class I, C | -0.0327761 |
| LMO7 | LIM domain 7 | -0.0327646 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0324902 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0320719 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0317231 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.031444 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0310944 |
| WWC1 | WW and C2 domain containing 1 | -0.0306997 |
| RBM25 | RNA binding motif protein 25 | -0.0306651 |
| EFNA5 | ephrin-A5 | -0.0300446 |
| NRP1 | neuropilin 1 | -0.0299753 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0297016 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0296243 |
| FUS | FUS RNA binding protein | -0.0293256 |
| EHBP1 | EH domain binding protein 1 | -0.0293181 |
| HLA-A | major histocompatibility complex, class I, A | -0.0292212 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0290009 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0287927 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0287486 |
| RPS19 | ribosomal protein S19 | -0.0287325 |
| NABP1 | nucleic acid binding protein 1 | -0.028441 |
| DST | dystonin | -0.0283831 |
| EMP1 | epithelial membrane protein 1 | -0.0281778 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0277132 |
| CLDN4 | claudin 4 | -0.0276278 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0273422 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0272843 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0272664 |
| SP100 | SP100 nuclear antigen | -0.0269769 |
| JUP | junction plakoglobin | -0.0267387 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.026704 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0266539 |
| SPAG9 | sperm associated antigen 9 | -0.0266229 |
| HMGA1 | high mobility group AT-hook 1 | -0.0264707 |
| RPL11 | ribosomal protein L11 | -0.0262779 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0261365 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0259366 |
| RPS3 | ribosomal protein S3 | -0.0257598 |
| MYO1E | myosin IE | -0.0257592 |
| NRG3 | neuregulin 3 | -0.0253278 |
| FHL2 | four and a half LIM domains 2 | -0.0252488 |
| LASP1 | LIM and SH3 protein 1 | -0.02505 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0249736 |
| RPS21 | ribosomal protein S21 | -0.0249282 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.02483 |
| MT1E | metallothionein 1E | -0.0248147 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0246641 |
| FLNA | filamin A, alpha | -0.0244712 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0244352 |
