| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bosentan (hydrate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bosentan (hydrate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.14312 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.1074 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.104656 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0865485 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0805787 |
| MEF2A | myocyte enhancer factor 2A | 0.0787504 |
| FNDC3B | fibronectin type III domain containing 3B | 0.078103 |
| NRG1 | neuregulin 1 | 0.0706752 |
| PTMA | prothymosin, alpha | 0.0653612 |
| DST | dystonin | 0.0624961 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0618446 |
| SPAG9 | sperm associated antigen 9 | 0.0612519 |
| OGA | O-GlcNAcase | 0.0598078 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0568747 |
| CCDC47 | coiled-coil domain containing 47 | 0.0562809 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0554309 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0553972 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0547754 |
| BBX | bobby sox homolog (Drosophila) | 0.0530612 |
| CANX | calnexin | 0.05188 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0517963 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0498581 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0473157 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0472285 |
| GOLGA4 | golgin A4 | 0.0458961 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0455254 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0454093 |
| CD46 | CD46 molecule, complement regulatory protein | 0.045305 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0451457 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.044671 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0446253 |
| PGK1 | phosphoglycerate kinase 1 | 0.0445155 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0429783 |
| RAD51B | RAD51 paralog B | 0.0422558 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0419855 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0410185 |
| ENO1 | enolase 1, (alpha) | 0.0408559 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0404683 |
| RPL23 | ribosomal protein L23 | 0.0402432 |
| HELZ | helicase with zinc finger | 0.0399375 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0399116 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0392921 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0390051 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0388693 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0388599 |
| RPL37A | ribosomal protein L37a | 0.0382076 |
| HIP1 | huntingtin interacting protein 1 | 0.0378757 |
| ZNF148 | zinc finger protein 148 | 0.0374263 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0367671 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0364751 |
| KLHL24 | kelch-like family member 24 | 0.036298 |
| CUX1 | cut-like homeobox 1 | 0.0362496 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0361264 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0361216 |
| WDR45B | WD repeat domain 45B | 0.0360641 |
| XPO1 | exportin 1 | 0.0358131 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0349867 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0349043 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0346585 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0346338 |
| TMF1 | TATA element modulatory factor 1 | 0.0344889 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0340532 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0339139 |
| USP37 | ubiquitin specific peptidase 37 | 0.0338151 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0338001 |
| FAM162A | family with sequence similarity 162, member A | 0.0334245 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0333073 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0331569 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0329264 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0327291 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.032713 |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 | 0.0321942 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0321665 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0319132 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0319088 |
| CDC27 | cell division cycle 27 | 0.0317448 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0317446 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0317394 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0316334 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0311965 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.031174 |
| PAPOLA | poly(A) polymerase alpha | 0.0311221 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0310121 |
| NREP | neuronal regeneration related protein | 0.0308763 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0308456 |
| MYO9A | myosin IXA | 0.0308279 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0307744 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0306517 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0304438 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0304313 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0300274 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0299557 |
| DPH6 | diphthamine biosynthesis 6 | 0.0297145 |
| SEPTIN2 | septin 2 | 0.029575 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0295272 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.029351 |
| ECT2 | epithelial cell transforming 2 | 0.0290117 |
| NF1 | neurofibromin 1 | 0.028701 |
| SQSTM1 | sequestosome 1 | 0.0286921 |
| USP34 | ubiquitin specific peptidase 34 | 0.0285239 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.421284 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.170131 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0640845 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0581616 |
| MAP1B | microtubule-associated protein 1B | -0.0530025 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0526089 |
| PLAT | plasminogen activator, tissue | -0.0478951 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0452334 |
| ACTG1 | actin gamma 1 | -0.0431771 |
| MEIS2 | Meis homeobox 2 | -0.040792 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0387048 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0378367 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0375739 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0357497 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0349212 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.034217 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0336015 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0320651 |
| NDRG1 | N-myc downstream regulated 1 | -0.0316563 |
| PKM | pyruvate kinase, muscle | -0.0312583 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0301526 |
| LPIN1 | lipin 1 | -0.0300917 |
| USP36 | ubiquitin specific peptidase 36 | -0.0294111 |
| BRD2 | bromodomain containing 2 | -0.0286216 |
| CADM2 | cell adhesion molecule 2 | -0.0280813 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0273119 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0273056 |
| TRIM25 | tripartite motif containing 25 | -0.0272799 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0267008 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.0264532 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0262755 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0261436 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0254354 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0252977 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0246621 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0245782 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.0245687 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.024471 |
| PTEN | phosphatase and tensin homolog | -0.0244276 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0242797 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0241634 |
| PCDH9 | protocadherin 9 | -0.0241279 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0234535 |
| TENM4 | teneurin transmembrane protein 4 | -0.0232129 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0228786 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0228759 |
| SH3PXD2B | SH3 and PX domains 2B | -0.0227274 |
| KLHL13 | kelch-like family member 13 | -0.0226882 |
| NRP1 | neuropilin 1 | -0.0225885 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0225543 |
| CSNK1D | casein kinase 1, delta | -0.0224632 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0221076 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | -0.0220836 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0217835 |
| BPTF | bromodomain PHD finger transcription factor | -0.0217078 |
| ACTN1 | actinin, alpha 1 | -0.0216932 |
| PLPP1 | phospholipid phosphatase 1 | -0.0216269 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0215478 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0212209 |
| MED15 | mediator complex subunit 15 | -0.0209845 |
| SMAD3 | SMAD family member 3 | -0.0206612 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0204617 |
| LYPLAL1 | lysophospholipase-like 1 | -0.0201667 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0201496 |
| ZNF875 | zinc finger protein 875 | -0.0200665 |
| SIK2 | salt-inducible kinase 2 | -0.0199812 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0199748 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0197136 |
| UBAP2L | ubiquitin associated protein 2-like | -0.0196708 |
| STC1 | stanniocalcin 1 | -0.019558 |
| ZNF292 | zinc finger protein 292 | -0.0195194 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0194782 |
| KIF21A | kinesin family member 21A | -0.0193318 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0193228 |
| TP53 | tumor protein p53 | -0.019249 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0192149 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0192016 |
| SF1 | splicing factor 1 | -0.0190618 |
| KLHL5 | kelch-like family member 5 | -0.0190189 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0189904 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0189429 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.0185549 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0184972 |
| MICU3 | mitochondrial calcium uptake family, member 3 | -0.0184923 |
| TSC22D2 | TSC22 domain family, member 2 | -0.018444 |
| IREB2 | iron-responsive element binding protein 2 | -0.0183739 |
| TPM1 | tropomyosin 1 (alpha) | -0.0182253 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0182237 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0180391 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.017994 |
| RNASEH2A | ribonuclease H2, subunit A | -0.0178922 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0178856 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -0.0178374 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0177759 |
| CALD1 | caldesmon 1 | -0.0177659 |
| GLI3 | GLI family zinc finger 3 | -0.0177353 |
| RPL36 | ribosomal protein L36 | -0.0177111 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0176624 |
| GOLGB1 | golgin B1 | -0.0175808 |
| WASF1 | WAS protein family, member 1 | -0.0175394 |
