| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bosentan (hydrate) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bosentan (hydrate)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLGA4 | golgin A4 | 0.0303716 |
| FAM13A | family with sequence similarity 13, member A | 0.0203294 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0179575 |
| TMF1 | TATA element modulatory factor 1 | 0.0118909 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.011029 |
| HELZ | helicase with zinc finger | 0.0107327 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0105435 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0101368 |
| ZNF292 | zinc finger protein 292 | 0.00982124 |
| CLINT1 | clathrin interactor 1 | 0.00968943 |
| RPL21 | ribosomal protein L21 | 0.00958572 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | 0.009517 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00950903 |
| SRP54 | signal recognition particle 54kDa | 0.0086859 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0083885 |
| SNX13 | sorting nexin 13 | 0.00817963 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.00809763 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00792325 |
| CEP57 | centrosomal protein 57kDa | 0.00783208 |
| RNF145 | ring finger protein 145 | 0.00774008 |
| KCNIP4 | Kv channel interacting protein 4 | 0.00752651 |
| SUCO | SUN domain containing ossification factor | 0.00745826 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.00741107 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.00740328 |
| TMEM39A | transmembrane protein 39A | 0.00714628 |
| PGM3 | phosphoglucomutase 3 | 0.00707885 |
| CCDC186 | coiled-coil domain containing 186 | 0.00707032 |
| UBQLN1 | ubiquilin 1 | 0.00692277 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0068353 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.00667024 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.0065246 |
| NBAS | neuroblastoma amplified sequence | 0.00652021 |
| NUP58 | nucleoporin 58 | 0.00650903 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00643652 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.00637382 |
| ARRDC3 | arrestin domain containing 3 | 0.00635185 |
| COG6 | component of oligomeric golgi complex 6 | 0.00632632 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.00629434 |
| SLK | STE20-like kinase | 0.00623916 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.00621676 |
| CSTB | cystatin B (stefin B) | 0.00618447 |
| SBDS | Shwachman-Bodian-Diamond syndrome | 0.00612888 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.00606664 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.00602333 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.00595411 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.00595215 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.00594947 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | 0.00591517 |
| ALPK1 | alpha-kinase 1 | 0.00583897 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0058127 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00581027 |
| NKTR | natural killer cell triggering receptor | 0.00578156 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.00577761 |
| RAB18 | RAB18, member RAS oncogene family | 0.00577496 |
| RPS7 | ribosomal protein S7 | 0.00572805 |
| WDR48 | WD repeat domain 48 | 0.00572774 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.00572169 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | 0.00562536 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.00560615 |
| PTEN | phosphatase and tensin homolog | 0.00560219 |
| UBXN7 | UBX domain protein 7 | 0.00551978 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00546278 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.00543572 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0054145 |
| AGR3 | anterior gradient 3 | 0.00538733 |
| KLHDC10 | kelch domain containing 10 | 0.00537685 |
| TPR | translocated promoter region, nuclear basket protein | 0.00536828 |
| PNN | pinin, desmosome associated protein | 0.00534222 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00532668 |
| STK17B | serine/threonine kinase 17b | 0.00529656 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.00528667 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00528646 |
| ZCCHC17 | zinc finger, CCHC domain containing 17 | 0.00523784 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.00522535 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.00521401 |
| CFAP36 | cilia and flagella associated protein 36 | 0.00520735 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.00519977 |
| VIRMA | vir like m6A methyltransferase associated | 0.00519594 |
| CCPG1 | cell cycle progression 1 | 0.00519039 |
| CPAP | centrosome assembly and centriole elongation protein | 0.00510399 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 | 0.00508424 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | 0.0050798 |
| THOC1 | THO complex 1 | 0.00507118 |
| MYADM | myeloid-associated differentiation marker | 0.0050652 |
| UBA5 | ubiquitin-like modifier activating enzyme 5 | 0.00504988 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.00504045 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00499331 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.00498043 |
| NUCB2 | nucleobindin 2 | 0.00495954 |
| CREBRF | CREB3 regulatory factor | 0.00495645 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.00494112 |
| POFUT2 | protein O-fucosyltransferase 2 | 0.00492226 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.00490533 |
| ZMYM6 | zinc finger, MYM-type 6 | 0.00489876 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.00489775 |
| MINDY3 | MINDY lysine 48 deubiquitinase 3 | 0.00489138 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.00488545 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.00488282 |
| GPATCH11 | G patch domain containing 11 | 0.00483696 |
| ZNF654 | zinc finger protein 654 | 0.00483098 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | -0.389891 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.191455 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.15833 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.120619 |
| TMSB10 | thymosin beta 10 | -0.11663 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.102832 |
| LMO7 | LIM domain 7 | -0.0988844 |
| EMP1 | epithelial membrane protein 1 | -0.0965105 |
| ANXA2 | annexin A2 | -0.0935044 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0882809 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0853952 |
| AHNAK | AHNAK nucleoprotein | -0.0832075 |
| ACTN4 | actinin, alpha 4 | -0.0814167 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0808553 |
| PTMA | prothymosin, alpha | -0.0807077 |
| FLNB | filamin B, beta | -0.0728933 |
| CALR | calreticulin | -0.0724503 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0720549 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0709119 |
| KRT8 | keratin 8, type II | -0.0672656 |
| TMC5 | transmembrane channel-like 5 | -0.0626936 |
| EZR | ezrin | -0.0600822 |
| UBC | ubiquitin C | -0.0578467 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0574951 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0564528 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0564438 |
| B2M | beta-2-microglobulin | -0.0556065 |
| BCL2L1 | BCL2-like 1 | -0.0549127 |
| H1-0 | H1.0 linker histone | -0.0541952 |
| FAT1 | FAT atypical cadherin 1 | -0.0505369 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.049909 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0490154 |
| RNF213 | ring finger protein 213 | -0.0486711 |
| NPSR1 | neuropeptide S receptor 1 | -0.0484055 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0477064 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0474868 |
| SEPTIN9 | septin 9 | -0.046204 |
| PKM | pyruvate kinase, muscle | -0.0455353 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0444082 |
| ASPH | aspartate beta-hydroxylase | -0.0439381 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.04347 |
| ITGA6 | integrin, alpha 6 | -0.042719 |
| EPCAM | epithelial cell adhesion molecule | -0.0426172 |
| RPS27A | ribosomal protein S27a | -0.0425838 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0408919 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.040574 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0393873 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0388872 |
| RUNX1 | runt-related transcription factor 1 | -0.0388249 |
| MCU | mitochondrial calcium uniporter | -0.0384169 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0374967 |
| MYOF | myoferlin | -0.037393 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.036423 |
| CMIP | c-Maf inducing protein | -0.0362875 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0361416 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0360236 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0359334 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0355625 |
| RPL23 | ribosomal protein L23 | -0.0353392 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0348368 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0347184 |
| EHBP1 | EH domain binding protein 1 | -0.0343953 |
| PGK1 | phosphoglycerate kinase 1 | -0.0342909 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0342372 |
| KRT18 | keratin 18, type I | -0.0339606 |
| MYO1E | myosin IE | -0.0338943 |
| RPS3 | ribosomal protein S3 | -0.0338027 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0336046 |
| CTBP2 | C-terminal binding protein 2 | -0.0335132 |
| AHR | aryl hydrocarbon receptor | -0.0334021 |
| VMP1 | vacuole membrane protein 1 | -0.033028 |
| S100A10 | S100 calcium binding protein A10 | -0.0328848 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0328746 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.032723 |
| PRKCA | protein kinase C, alpha | -0.0326642 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0326463 |
| HLA-E | major histocompatibility complex, class I, E | -0.0324797 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0323555 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0318033 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0315721 |
| GNAS | GNAS complex locus | -0.031536 |
| CANX | calnexin | -0.0306031 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.030459 |
| ACTG1 | actin gamma 1 | -0.0302764 |
| ENO1 | enolase 1, (alpha) | -0.03009 |
| PLEC | plectin | -0.0297798 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0296979 |
| CUX1 | cut-like homeobox 1 | -0.0295974 |
| HLA-A | major histocompatibility complex, class I, A | -0.029589 |
| CD2AP | CD2-associated protein | -0.0295093 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0293759 |
| ITGB4 | integrin, beta 4 | -0.029366 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0292483 |
| VCL | vinculin | -0.0292304 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0292286 |
| TPM4 | tropomyosin 4 | -0.0290204 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.028821 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0287014 |
| KRT7 | keratin 7, type II | -0.0286323 |
| FBXO11 | F-box protein 11 | -0.0285794 |
