| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bosentan (hydrate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bosentan (hydrate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.153801 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.113996 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.104642 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.104304 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.103619 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0925784 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0874509 |
| CANX | calnexin | 0.0746634 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0743635 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0719018 |
| FAM13A | family with sequence similarity 13, member A | 0.0718203 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0589319 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0558271 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0501482 |
| ZNF292 | zinc finger protein 292 | 0.0441561 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0441458 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0416734 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0407403 |
| RNF145 | ring finger protein 145 | 0.0404356 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0392851 |
| PGK1 | phosphoglycerate kinase 1 | 0.0383634 |
| PTMA | prothymosin, alpha | 0.0378163 |
| ENO1 | enolase 1, (alpha) | 0.0377565 |
| CADM1 | cell adhesion molecule 1 | 0.0361079 |
| WDR45B | WD repeat domain 45B | 0.0356027 |
| NEK7 | NIMA-related kinase 7 | 0.0348868 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0347549 |
| PRELID2 | PRELI domain containing 2 | 0.0347187 |
| INSIG2 | insulin induced gene 2 | 0.0345807 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.033411 |
| HELZ | helicase with zinc finger | 0.0332673 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0329148 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.03288 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0319911 |
| GOLGA4 | golgin A4 | 0.0315223 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0314657 |
| CD109 | CD109 molecule | 0.0306944 |
| PLIN2 | perilipin 2 | 0.0305191 |
| TMSB4X | thymosin beta 4, X-linked | 0.0303382 |
| SPAG9 | sperm associated antigen 9 | 0.0299816 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0295966 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0295765 |
| AFDN | afadin, adherens junction formation factor | 0.0294681 |
| QKI | QKI, KH domain containing, RNA binding | 0.0284729 |
| NUP58 | nucleoporin 58 | 0.0284087 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0281094 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0278937 |
| OGA | O-GlcNAcase | 0.0274735 |
| RBM39 | RNA binding motif protein 39 | 0.0274595 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0273404 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.027118 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0268868 |
| YME1L1 | YME1-like 1 ATPase | 0.0265113 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0263743 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0263052 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0257793 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0256909 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0254619 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0247565 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0243171 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0242922 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0240389 |
| SEPTIN7 | septin 7 | 0.0239917 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0237976 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0237592 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0237509 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0237271 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0235301 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0233793 |
| SUCO | SUN domain containing ossification factor | 0.0231693 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0231004 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0230752 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0229115 |
| RLF | rearranged L-myc fusion | 0.0228788 |
| FMNL2 | formin-like 2 | 0.0226409 |
| WDR43 | WD repeat domain 43 | 0.0225921 |
| S100A6 | S100 calcium binding protein A6 | 0.0225295 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0225143 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0224903 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0223893 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0223764 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0222493 |
| TPD52 | tumor protein D52 | 0.0222126 |
| STC2 | stanniocalcin 2 | 0.0221747 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0220981 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0218665 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0218092 |
| NOP58 | NOP58 ribonucleoprotein | 0.0217931 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0217111 |
| PTK2 | protein tyrosine kinase 2 | 0.020933 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0205173 |
| RIOK3 | RIO kinase 3 | 0.0204313 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0204212 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0203559 |
| CLINT1 | clathrin interactor 1 | 0.0202875 |
| B2M | beta-2-microglobulin | 0.020243 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0201747 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0198787 |
| RPL23 | ribosomal protein L23 | 0.0196807 |
| XPO1 | exportin 1 | 0.0196581 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.309589 |
| EXT1 | exostosin glycosyltransferase 1 | -0.193162 |
| VCL | vinculin | -0.123622 |
| NRP1 | neuropilin 1 | -0.122437 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.118739 |
| FN1 | fibronectin 1 | -0.106967 |
| GLIS3 | GLIS family zinc finger 3 | -0.104974 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0963706 |
| OSMR | oncostatin M receptor | -0.0913557 |
| TMEM156 | transmembrane protein 156 | -0.0811553 |
| NTN4 | netrin 4 | -0.0802445 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.077257 |
| HMGA2 | high mobility group AT-hook 2 | -0.0679484 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0600698 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0576219 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0572015 |
| RAB31 | RAB31, member RAS oncogene family | -0.0571103 |
| KSR1 | kinase suppressor of ras 1 | -0.0567173 |
| NRG1 | neuregulin 1 | -0.0564691 |
| SYT1 | synaptotagmin I | -0.0540154 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0536625 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.051839 |
| SMAD3 | SMAD family member 3 | -0.0514312 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0507293 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0499915 |
| CD44 | CD44 molecule (Indian blood group) | -0.0489253 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0481431 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0466844 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0465288 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0464551 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0461457 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0450151 |
| PALLD | palladin, cytoskeletal associated protein | -0.044936 |
| EGR1 | early growth response 1 | -0.0444078 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0435617 |
| FHL2 | four and a half LIM domains 2 | -0.0431009 |
| RUNX2 | runt-related transcription factor 2 | -0.0422764 |
| MT2A | metallothionein 2A | -0.0413447 |
| SEPTIN9 | septin 9 | -0.0407206 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0405699 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0403991 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.040022 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0392346 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0392145 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0388365 |
| ETV6 | ets variant 6 | -0.0374541 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0373867 |
| ITGA1 | integrin, alpha 1 | -0.0364598 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.035517 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0355167 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0353138 |
| MAP1B | microtubule-associated protein 1B | -0.0347504 |
| SMOX | spermine oxidase | -0.0341746 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0341669 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0340801 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0338966 |
| SVIL | supervillin | -0.0338317 |
| FOXP1 | forkhead box P1 | -0.0336447 |
| AOPEP | aminopeptidase O (putative) | -0.0325603 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0318546 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.031152 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0309475 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0308635 |
| GLCCI1 | glucocorticoid induced 1 | -0.030784 |
| VMP1 | vacuole membrane protein 1 | -0.0304277 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0304208 |
| ZNF644 | zinc finger protein 644 | -0.0303865 |
| NDRG1 | N-myc downstream regulated 1 | -0.0300386 |
| FAM20C | family with sequence similarity 20, member C | -0.0299737 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0299651 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0297528 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0296334 |
| VEGFA | vascular endothelial growth factor A | -0.0295467 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.028904 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0288491 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0286137 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0283954 |
| FAF2 | Fas associated factor family member 2 | -0.0281857 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0279385 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0277845 |
| ACTN1 | actinin, alpha 1 | -0.0275652 |
| CAB39 | calcium binding protein 39 | -0.0275098 |
| WDR1 | WD repeat domain 1 | -0.0273534 |
| COPA | coatomer protein complex, subunit alpha | -0.0273 |
| RNF213 | ring finger protein 213 | -0.0272865 |
| FTL | ferritin, light polypeptide | -0.0272787 |
| GPATCH2L | G patch domain containing 2-like | -0.0271734 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0269482 |
| NAV1 | neuron navigator 1 | -0.0268582 |
| FAM3C | family with sequence similarity 3, member C | -0.0264774 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0263018 |
| RAB10 | RAB10, member RAS oncogene family | -0.0262186 |
| TOP1 | topoisomerase (DNA) I | -0.0261451 |
| TGFB1 | transforming growth factor, beta 1 | -0.0261375 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0259393 |
| DUSP5 | dual specificity phosphatase 5 | -0.0259385 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0259294 |
| THBS1 | thrombospondin 1 | -0.025927 |
| EPN2 | epsin 2 | -0.0258932 |
| FOSL2 | FOS-like antigen 2 | -0.0258574 |
