| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bosentan (hydrate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bosentan (hydrate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.14977 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.097406 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0780964 |
| CDH13 | cadherin 13 | 0.0723943 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0644265 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0613412 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0569343 |
| NAV2 | neuron navigator 2 | 0.0531266 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0498074 |
| PGK1 | phosphoglycerate kinase 1 | 0.0487387 |
| CANX | calnexin | 0.0444072 |
| KRT18 | keratin 18, type I | 0.0431235 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0416949 |
| ENO1 | enolase 1, (alpha) | 0.0405818 |
| ASPH | aspartate beta-hydroxylase | 0.0396237 |
| FRMD5 | FERM domain containing 5 | 0.0350297 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0346699 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0322011 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.031703 |
| PTMA | prothymosin, alpha | 0.0311332 |
| LDHA | lactate dehydrogenase A | 0.0311204 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0308855 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0306795 |
| RPS3 | ribosomal protein S3 | 0.030482 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0295879 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.028141 |
| AFDN | afadin, adherens junction formation factor | 0.0258764 |
| OGA | O-GlcNAcase | 0.0258413 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0250809 |
| TFRC | transferrin receptor | 0.0250383 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0244023 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0243299 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0242922 |
| KIZ | kizuna centrosomal protein | 0.0240968 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0235167 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0234482 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0231264 |
| AHNAK | AHNAK nucleoprotein | 0.0230082 |
| CDK6 | cyclin-dependent kinase 6 | 0.0224081 |
| SERINC1 | serine incorporator 1 | 0.0221542 |
| PRRC2C | proline-rich coiled-coil 2C | 0.022012 |
| FMNL2 | formin-like 2 | 0.0218714 |
| TMF1 | TATA element modulatory factor 1 | 0.0213402 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0211308 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0209905 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0209813 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0209739 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0205107 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.01994 |
| TES | testin LIM domain protein | 0.0198768 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0197293 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0197211 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0196984 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0196547 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0192517 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0189516 |
| INSIG2 | insulin induced gene 2 | 0.0186996 |
| TRIM56 | tripartite motif containing 56 | 0.0184127 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0177422 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | 0.0175287 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.01749 |
| ANKRD36 | ankyrin repeat domain 36 | 0.01748 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0173674 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0172081 |
| TMSB4X | thymosin beta 4, X-linked | 0.0166321 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0166219 |
| EPCAM | epithelial cell adhesion molecule | 0.0165905 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0161987 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0160208 |
| SPAG9 | sperm associated antigen 9 | 0.0158395 |
| TMEM163 | transmembrane protein 163 | 0.0158355 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0158327 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0157427 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0156165 |
| KCNIP4 | Kv channel interacting protein 4 | 0.0156102 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0154874 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0154029 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0149634 |
| CALR | calreticulin | 0.0149141 |
| CDHR3 | cadherin-related family member 3 | 0.0147724 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0146898 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0146795 |
| NONO | non-POU domain containing, octamer-binding | 0.014661 |
| PRELID2 | PRELI domain containing 2 | 0.0142681 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0142254 |
| STX16 | syntaxin 16 | 0.0142065 |
| RANBP2 | RAN binding protein 2 | 0.0141774 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0141204 |
| RPS27A | ribosomal protein S27a | 0.0140921 |
| MYOF | myoferlin | 0.0140783 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0140135 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0138165 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0137757 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0136464 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0135821 |
| HELZ | helicase with zinc finger | 0.0135685 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0135148 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0134534 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0133339 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0133255 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.31888 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.171588 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.130158 |
| TNS3 | tensin 3 | -0.120466 |
| EGR1 | early growth response 1 | -0.0963885 |
| ACTN4 | actinin, alpha 4 | -0.0896913 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0884789 |
| EZR | ezrin | -0.0870764 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.083182 |
| RUNX1 | runt-related transcription factor 1 | -0.0806269 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0752216 |
| ACTG1 | actin gamma 1 | -0.07217 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0664894 |
| HDAC4 | histone deacetylase 4 | -0.0659147 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0646196 |
| HMGA1 | high mobility group AT-hook 1 | -0.0634258 |
| EFNB2 | ephrin-B2 | -0.0606621 |
| AOPEP | aminopeptidase O (putative) | -0.0589047 |
| BCL2L1 | BCL2-like 1 | -0.0586092 |
| PKM | pyruvate kinase, muscle | -0.0582158 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0577815 |
| ANXA2 | annexin A2 | -0.0570564 |
| RPS6 | ribosomal protein S6 | -0.0549345 |
| RPL35A | ribosomal protein L35a | -0.0533749 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0528379 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0522801 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0498769 |
| ATXN1 | ataxin 1 | -0.0497512 |
| PCBP2 | poly(rC) binding protein 2 | -0.0494236 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0489904 |
| PROX1 | prospero homeobox 1 | -0.0483554 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0483444 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0461238 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0434566 |
| LMO7 | LIM domain 7 | -0.0431645 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0421016 |
| ABHD2 | abhydrolase domain containing 2 | -0.041896 |
| POTEF | POTE ankyrin domain family, member F | -0.0418618 |
| SVIL | supervillin | -0.0417644 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.041438 |
| RNF43 | ring finger protein 43 | -0.0411297 |
| MED13 | mediator complex subunit 13 | -0.0411087 |
| RPLP1 | ribosomal protein, large, P1 | -0.0407836 |
| BMP5 | bone morphogenetic protein 5 | -0.0407752 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.0405482 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0398698 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -0.0391583 |
| ZNRF3 | zinc and ring finger 3 | -0.0391083 |
| PFN1 | profilin 1 | -0.0389256 |
| VCL | vinculin | -0.0388566 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0385238 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0382891 |
| OXR1 | oxidation resistance 1 | -0.0382302 |
| TNS4 | tensin 4 | -0.0380543 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0376824 |
| JMJD1C | jumonji domain containing 1C | -0.0368267 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0366613 |
| BRD2 | bromodomain containing 2 | -0.0363569 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0362234 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.035491 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0351438 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0351188 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0344721 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0340518 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0339956 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | -0.0330235 |
| RPL28 | ribosomal protein L28 | -0.0328781 |
| ETNK1 | ethanolamine kinase 1 | -0.0321736 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0317703 |
| YBX1 | Y box binding protein 1 | -0.0317326 |
| FOXP1 | forkhead box P1 | -0.0316869 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0314583 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0314358 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0312293 |
| RTN4 | reticulon 4 | -0.0309929 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0298429 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.029791 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0296593 |
| FLNA | filamin A, alpha | -0.0296436 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -0.0295443 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0295429 |
| ETV5 | ets variant 5 | -0.0294985 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0294812 |
| IRS2 | insulin receptor substrate 2 | -0.0292161 |
| CLTC | clathrin, heavy chain (Hc) | -0.0291247 |
| CENPF | centromere protein F, 350/400kDa | -0.0290123 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0285457 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.0280883 |
| ECT2 | epithelial cell transforming 2 | -0.0279213 |
| FOSL1 | FOS-like antigen 1 | -0.0275221 |
| RPS8 | ribosomal protein S8 | -0.0273911 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0271746 |
| WASF2 | WAS protein family, member 2 | -0.0270984 |
| LRP6 | low density lipoprotein receptor-related protein 6 | -0.0269471 |
| EPHA2 | EPH receptor A2 | -0.0267573 |
| RAB22A | RAB22A, member RAS oncogene family | -0.026583 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0265787 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.0261921 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0255076 |
| CMIP | c-Maf inducing protein | -0.0254294 |
