Brachydactyly Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A bone development disease characterized by short fingers and toes. (Human Disease Ontology, DOID_0050581)
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Genes

646 genes co-occuring with the disease Brachydactyly in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
GDF5 growth differentiation factor 5 3.109
IHH indian hedgehog 2.863
GNAS GNAS complex locus 2.811
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 2.802
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 2.795
HOXD13 homeobox D13 2.608
ADAMTSL2 ADAMTS-like 2 2.605
PDE3A phosphodiesterase 3A, cGMP-inhibited 2.594
BMPR1B bone morphogenetic protein receptor, type IB 2.568
PTHLH parathyroid hormone-like hormone 2.538
PTH parathyroid hormone 2.516
TRPS1 trichorhinophalangeal syndrome I 2.489
PDE4D phosphodiesterase 4D, cAMP-specific 2.447
HDAC4 histone deacetylase 4 2.438
STX16 syntaxin 16 2.43
FBN1 fibrillin 1 2.416
B3GLCT beta 3-glucosyltransferase 2.408
CHSY1 chondroitin sulfate synthase 1 2.395
F8 coagulation factor VIII, procoagulant component 2.382
GHRH growth hormone releasing hormone 2.357
NOG noggin 2.343
ANKRD11 ankyrin repeat domain 11 2.337
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 2.333
BBS1 Bardet-Biedl syndrome 1 2.329
LTBP2 latent transforming growth factor beta binding protein 2 2.306
ACAN aggrecan 2.282
FGFR3 fibroblast growth factor receptor 3 2.273
BBS10 Bardet-Biedl syndrome 10 2.252
PLPPR3 phospholipid phosphatase related 3 2.249
WDR35 WD repeat domain 35 2.239
COL2A1 collagen, type II, alpha 1 2.238
ROR2 receptor tyrosine kinase-like orphan receptor 2 2.233
IFT43 intraflagellar transport 43 2.231
OFD1 oral-facial-digital syndrome 1 2.206
WDR19 WD repeat domain 19 2.201
PTH1R parathyroid hormone 1 receptor 2.179
SOX9 SRY (sex determining region Y)-box 9 2.165
BBS7 Bardet-Biedl syndrome 7 2.159
BBS2 Bardet-Biedl syndrome 2 2.157
BBS12 Bardet-Biedl syndrome 12 2.155
RUNX2 runt-related transcription factor 2 2.155
WNT5A wingless-type MMTV integration site family, member 5A 2.15
SHH sonic hedgehog 2.147
BBS9 Bardet-Biedl syndrome 9 2.143
LTBP3 latent transforming growth factor beta binding protein 3 2.14
EXT1 exostosin glycosyltransferase 1 2.125
BBS5 Bardet-Biedl syndrome 5 2.12
FBN2 fibrillin 2 2.092
IFT122 intraflagellar transport 122 2.082
SLC26A2 solute carrier family 26 (anion exchanger), member 2 2.064
TTC8 tetratricopeptide repeat domain 8 2.063
IFT80 intraflagellar transport 80 2.051
IFT140 intraflagellar transport 140 2.045
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 2.039
RAI1 retinoic acid induced 1 2.038
BBS4 Bardet-Biedl syndrome 4 2.038
SHOX short stature homeobox 2.031
TTC21B tetratricopeptide repeat domain 21B 2.026
GLI3 GLI family zinc finger 3 2.003
PRMT7 protein arginine methyltransferase 7 2.001
NPR2 natriuretic peptide receptor 2 1.989
IFT172 intraflagellar transport 172 1.987
EVC2 Ellis van Creveld syndrome 2 1.967
BMP2 bone morphogenetic protein 2 1.955
TRPV4 transient receptor potential cation channel, subfamily V, member 4 1.942
ACVR1 activin A receptor, type I 1.934
WDPCP WD repeat containing planar cell polarity effector 1.931
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 1.93
MKS1 Meckel syndrome, type 1 1.927
TBRG1 transforming growth factor beta regulator 1 1.915
BMP4 bone morphogenetic protein 4 1.903
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 1.896
HOXA13 homeobox A13 1.894
EPHA4 EPH receptor A4 1.894
BBIP1 BBSome interacting protein 1 1.89
MSX2 msh homeobox 2 1.886
PLPPR4 phospholipid phosphatase related 4 1.885
FGD1 FYVE, RhoGEF and PH domain containing 1 1.88
LMBR1 limb development membrane protein 1 1.876
ADAMTSL4 ADAMTS-like 4 1.874
WNT6 wingless-type MMTV integration site family, member 6 1.867
CEP290 centrosomal protein 290kDa 1.866
YY1AP1 YY1 associated protein 1 1.864
PTCH1 patched 1 1.853
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 1.845
IFT52 intraflagellar transport 52 1.844
RSPRY1 ring finger and SPRY domain containing 1 1.84
DNM3 dynamin 3 1.836
NPPC natriuretic peptide C 1.828
GDF6 growth differentiation factor 6 1.822
COL9A2 collagen, type IX, alpha 2 1.821
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 1.818
DVL1 dishevelled segment polarity protein 1 1.816
TGFB1 transforming growth factor, beta 1 1.815
IFT27 intraflagellar transport 27 1.812
SCAPER S-phase cyclin A-associated protein in the ER 1.809
KMT2D lysine (K)-specific methyltransferase 2D 1.801
RORA RAR-related orphan receptor A 1.8
SDCCAG8 serologically defined colon cancer antigen 8 1.791
RAB23 RAB23, member RAS oncogene family 1.789
IGF1 insulin-like growth factor 1 (somatomedin C) 1.787
COL9A1 collagen, type IX, alpha 1 1.783
SMAD9 SMAD family member 9 1.782
BMPR1A bone morphogenetic protein receptor, type IA 1.779
POFUT2 protein O-fucosyltransferase 2 1.774
FGFR2 fibroblast growth factor receptor 2 1.754
POC1A POC1 centriolar protein A 1.753
FZD2 frizzled class receptor 2 1.752
VWF von Willebrand factor 1.751
COMP cartilage oligomeric matrix protein 1.732
NPHP1 nephronophthisis 1 (juvenile) 1.728
ALMS1 Alstrom syndrome protein 1 1.727
DVL3 dishevelled segment polarity protein 3 1.724
KDM6A lysine (K)-specific demethylase 6A 1.722
FGF8 fibroblast growth factor 8 (androgen-induced) 1.719
MATN3 matrilin 3 1.716
TMEM67 transmembrane protein 67 1.716
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 1.71
COG4 component of oligomeric golgi complex 4 1.708
FGFR1 fibroblast growth factor receptor 1 1.706
PRKG2 protein kinase, cGMP-dependent, type II 1.704
LTBP1 latent transforming growth factor beta binding protein 1 1.704
ALG6 ALG6, alpha-1,3-glucosyltransferase 1.701
MANSC4 MANSC domain containing 4 1.7
EXTL3 exostosin-like glycosyltransferase 3 1.698
CEP120 centrosomal protein 120kDa 1.698
WNT9A wingless-type MMTV integration site family, member 9A 1.685
PAX3 paired box 3 1.683
PITX1 paired-like homeodomain 1 1.68
NIPBL Nipped-B homolog (Drosophila) 1.673
ARID1B AT rich interactive domain 1B (SWI1-like) 1.671
GLI1 GLI family zinc finger 1 1.669
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 1.666
INTU inturned planar cell polarity protein 1.663
EHMT1 euchromatic histone-lysine N-methyltransferase 1 1.661
SP7 Sp7 transcription factor 1.661
DLX5 distal-less homeobox 5 1.66
IFT54 intraflagellar transport 54 1.656
VANGL2 VANGL planar cell polarity protein 2 1.655
KIAA0586 KIAA0586 1.653
COL10A1 collagen, type X, alpha 1 1.648
TRIM8 tripartite motif containing 8 1.643
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 1.642
SMAD4 SMAD family member 4 1.635
COL9A3 collagen, type IX, alpha 3 1.632
LZTFL1 leucine zipper transcription factor-like 1 1.632
RAD21 RAD21 homolog (S. pombe) 1.62
ADAMTSL1 ADAMTS-like 1 1.618
BMP7 bone morphogenetic protein 7 1.618
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 1.613
FUZ fuzzy planar cell polarity protein 1.612
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.609
GLI2 GLI family zinc finger 2 1.604
F9 coagulation factor IX 1.603
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.603
NEK1 NIMA-related kinase 1 1.6
ZNF778 zinc finger protein 778 1.6
MSX1 msh homeobox 1 1.599
COL1A1 collagen, type I, alpha 1 1.599
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.599
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 1.598
PCNT pericentrin 1.597
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 1.593
SLURP1 secreted LY6/PLAUR domain containing 1 1.592
TMEM11 transmembrane protein 11 1.585
CNTLN centlein, centrosomal protein 1.577
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.569
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 1.566
TBX5 T-box 5 1.564
SRCAP Snf2-related CREBBP activator protein 1.561
SMC1A structural maintenance of chromosomes 1A 1.56
ARHGAP31 Rho GTPase activating protein 31 1.554
CREBBP CREB binding protein 1.553
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.547
TMEM216 transmembrane protein 216 1.544
CTCF CCCTC-binding factor (zinc finger protein) 1.544
TBX6 T-box 6 1.539
TCTN3 tectonic family member 3 1.538
SMO smoothened, frizzled class receptor 1.538
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 1.536
CANT1 calcium activated nucleotidase 1 1.535
EXT2 exostosin glycosyltransferase 2 1.533
IFT74 intraflagellar transport 74 1.527
HOXD12 homeobox D12 1.525
SOX5 SRY (sex determining region Y)-box 5 1.525
NXN nucleoredoxin 1.522
PITX2 paired-like homeodomain 2 1.522
EVX2 even-skipped homeobox 2 1.521
HDAC8 histone deacetylase 8 1.52
IFT81 intraflagellar transport 81 1.519
ARL13B ADP-ribosylation factor-like 13B 1.516
KIF1A kinesin family member 1A 1.512
CERS3 ceramide synthase 3 1.509
FGF4 fibroblast growth factor 4 1.509
CDON cell adhesion associated, oncogene regulated 1.502
WNT3A wingless-type MMTV integration site family, member 3A 1.501
OTX2 orthodenticle homeobox 2 1.5
COL1A2 collagen, type I, alpha 2 1.498
SMC3 structural maintenance of chromosomes 3 1.497
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 1.497
FURIN furin (paired basic amino acid cleaving enzyme) 1.496
LTBP4 latent transforming growth factor beta binding protein 4 1.496
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.492
EVC Ellis van Creveld protein 1.491
SOST sclerostin 1.489
WNT1 wingless-type MMTV integration site family, member 1 1.488
DCAF5 DDB1 and CUL4 associated factor 5 1.486
DOCK6 dedicator of cytokinesis 6 1.486
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 1.483
KIAA0753 KIAA0753 1.483
HDLBP high density lipoprotein binding protein 1.478
FOXC1 forkhead box C1 1.477
FGF3 fibroblast growth factor 3 1.474
LRP5 low density lipoprotein receptor-related protein 5 1.472
KIF7 kinesin family member 7 1.472
PAX6 paired box 6 1.471
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 1.47
ARSL arylsulfatase L 1.47
BGLAP bone gamma-carboxyglutamate (gla) protein 1.469
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 1.468
ALB albumin 1.466
POMC proopiomelanocortin 1.466
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 1.465
INVS inversin 1.465
GPC1 glypican 1 1.465
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.462
CHPF2 chondroitin polymerizing factor 2 1.461
CRIPT cysteine-rich PDZ-binding protein 1.456
FGF9 fibroblast growth factor 9 1.456
DYM dymeclin 1.454
FGF10 fibroblast growth factor 10 1.446
MMP13 matrix metallopeptidase 13 1.445
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 1.445
ALG8 ALG8, alpha-1,3-glucosyltransferase 1.445
REP15 RAB15 effector protein 1.441
RPGRIP1L RPGRIP1-like 1.438
DHH desert hedgehog 1.437
B3GAT3 beta-1,3-glucuronyltransferase 3 1.436
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 1.432
FBN3 fibrillin 3 1.431
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.431
WNT10B wingless-type MMTV integration site family, member 10B 1.43
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 1.43
FLNA filamin A, alpha 1.43
CHRD chordin 1.428
NSD1 nuclear receptor binding SET domain protein 1 1.428
PTDSS1 phosphatidylserine synthase 1 1.423
WNT7A wingless-type MMTV integration site family, member 7A 1.423
SAMD15 sterile alpha motif domain containing 15 1.423
NBAS neuroblastoma amplified sequence 1.422
NEPRO nucleolus and neural progenitor protein 1.421
CEP164 centrosomal protein 164kDa 1.417
TWIST2 twist family bHLH transcription factor 2 1.417
COL11A1 collagen, type XI, alpha 1 1.416
TWIST1 twist family bHLH transcription factor 1 1.416
FOXE3 forkhead box E3 1.413
PRRX1 paired related homeobox 1 1.41
IFT20 intraflagellar transport 20 1.41
JAG1 jagged 1 1.409
HOXD11 homeobox D11 1.408
CC2D2A coiled-coil and C2 domain containing 2A 1.408
FGF18 fibroblast growth factor 18 1.408
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 1.407
EP300 E1A binding protein p300 1.406
BANF1 barrier to autointegration factor 1 1.406
IQCE IQ motif containing E 1.404
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 1.404
CEP41 centrosomal protein 41kDa 1.402
MAGEL2 melanoma antigen family L2 1.402
SMAD6 SMAD family member 6 1.401
FGF16 fibroblast growth factor 16 1.401
ALX4 ALX homeobox 4 1.399
C2CD3 C2 calcium-dependent domain containing 3 1.396
IGFBP3 insulin-like growth factor binding protein 3 1.392
GREM1 gremlin 1, DAN family BMP antagonist 1.391
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 1.391
MCFD2 multiple coagulation factor deficiency 2 1.388
IFT88 intraflagellar transport 88 1.388
SUFU suppressor of fused homolog (Drosophila) 1.387
GREM2 gremlin 2, DAN family BMP antagonist 1.385
SFRP4 secreted frizzled-related protein 4 1.384
ALG12 ALG12, alpha-1,6-mannosyltransferase 1.384
C1ORF105 chromosome 1 open reading frame 105 1.383
UBE3B ubiquitin protein ligase E3B 1.382
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.381
SFRP2 secreted frizzled-related protein 2 1.379
SOX11 SRY (sex determining region Y)-box 11 1.375
SNRPN small nuclear ribonucleoprotein polypeptide N 1.373
FGF17 fibroblast growth factor 17 1.373
ATXN2L ataxin 2-like 1.37
FGF20 fibroblast growth factor 20 1.367
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.366
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.364
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 1.364
PRICKLE1 prickle homolog 1 (Drosophila) 1.362
PAPLN papilin, proteoglycan-like sulfated glycoprotein 1.361
XYLT1 xylosyltransferase I 1.357
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 1.355
FGF22 fibroblast growth factor 22 1.354
EPHA7 EPH receptor A7 1.353
ADAMTSL3 ADAMTS-like 3 1.353
FGF5 fibroblast growth factor 5 1.353
SIM1 single-minded family bHLH transcription factor 1 1.352
FGF6 fibroblast growth factor 6 1.352
LMAN1 lectin, mannose-binding, 1 1.35
CCDC28B coiled-coil domain containing 28B 1.349
CHD7 chromodomain helicase DNA binding protein 7 1.346
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2 1.344
TBX1 T-box 1 1.344
STK25 serine/threonine kinase 25 1.343
TCTN2 tectonic family member 2 1.343
IGF2 insulin-like growth factor 2 1.342
FGF7 fibroblast growth factor 7 1.341
NPHP3 nephronophthisis 3 (adolescent) 1.34
HAND2 heart and neural crest derivatives expressed 2 1.339
INS insulin 1.336
SCLT1 sodium channel and clathrin linker 1 1.336
H3-3B H3.3 histone B 1.336
MBD5 methyl-CpG binding domain protein 5 1.335
H3-4 H3.4 histone, cluster member 1.334
H3C13 H3 clustered histone 13 1.334
H3-5 H3.5 histone 1.334
NOXRED1 NADP-dependent oxidoreductase domain containing 1 1.332
FMR1 fragile X mental retardation 1 1.33
H3C12 H3 clustered histone 12 1.329
MECP2 methyl CpG binding protein 2 1.328
TMEM231 transmembrane protein 231 1.32
KIF3A kinesin family member 3A 1.319
SRY sex determining region Y 1.318
DNAH8 dynein, axonemal, heavy chain 8 1.317
ALG11 ALG11, alpha-1,2-mannosyltransferase 1.311
KAT6B K(lysine) acetyltransferase 6B 1.311
PGM3 phosphoglucomutase 3 1.31
CCP110 centriolar coiled coil protein 110kDa 1.307
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 1.306
RYK receptor-like tyrosine kinase 1.306
AHI1 Abelson helper integration site 1 1.303
ZFP57 ZFP57 zinc finger protein 1.301
TNXB tenascin XB 1.301
HDAC9 histone deacetylase 9 1.299
YIPF2 Yip1 domain family, member 2 1.297
DPF2 D4, zinc and double PHD fingers family 2 1.293
SYNJ2BP-COX16 SYNJ2BP-COX16 readthrough 1.289
HSPG2 heparan sulfate proteoglycan 2 1.289
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 1.288
SPATA1 spermatogenesis associated 1 1.288
SIX3 SIX homeobox 3 1.288
HHIP hedgehog interacting protein 1.288
DLX2 distal-less homeobox 2 1.287
DSPP dentin sialophosphoprotein 1.287
WNT4 wingless-type MMTV integration site family, member 4 1.287
NKX3-2 NK3 homeobox 2 1.286
NPHP4 nephronophthisis 4 1.285
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 1.284
TCF12 transcription factor 12 1.283
RTTN rotatin 1.281
FBXW4 F-box and WD repeat domain containing 4 1.28
PRICKLE4 prickle homolog 4 (Drosophila) 1.279
CHPF chondroitin polymerizing factor 1.279
TMEM53 transmembrane protein 53 1.277
LMNA lamin A/C 1.275
OBSL1 obscurin-like 1 1.275
GPC6 glypican 6 1.272
PHEX phosphate regulating endopeptidase homolog, X-linked 1.27
PRICKLE3 prickle homolog 3 (Drosophila) 1.27
IQCB1 IQ motif containing B1 1.269
SOX2 SRY (sex determining region Y)-box 2 1.268
MATN1 matrilin 1, cartilage matrix protein 1.267
PAPPA2 pappalysin 2 1.267
FAM20B family with sequence similarity 20, member B 1.266
LRP6 low density lipoprotein receptor-related protein 6 1.265
TRIP11 thyroid hormone receptor interactor 11 1.264
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 1.264
KREMEN2 kringle containing transmembrane protein 2 1.261
LNPK lunapark, ER junction formation factor 1.261
COL11A2 collagen, type XI, alpha 2 1.258
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.257
BMP3 bone morphogenetic protein 3 1.257
LYSMD4 LysM, putative peptidoglycan-binding, domain containing 4 1.256
LHX4 LIM homeobox 4 1.254
VANGL1 VANGL planar cell polarity protein 1 1.254
WNT16 wingless-type MMTV integration site family, member 16 1.248
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.244
SOX6 SRY (sex determining region Y)-box 6 1.243
SMAD5 SMAD family member 5 1.242
EFNB1 ephrin-B1 1.242
TGFBR1 transforming growth factor, beta receptor 1 1.241
DVL2 dishevelled segment polarity protein 2 1.24
DPCD deleted in primary ciliary dyskinesia homolog (mouse) 1.237
ACTB actin, beta 1.236
KMT2A lysine (K)-specific methyltransferase 2A 1.234
HOXA11 homeobox A11 1.233
DONSON downstream neighbor of SON 1.232
CEP57 centrosomal protein 57kDa 1.232
FRZB frizzled-related protein 1.232
DLX6 distal-less homeobox 6 1.23
NDN necdin, melanoma antigen (MAGE) family member 1.23
FGF13 fibroblast growth factor 13 1.229
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase 1.227
GHRHR growth hormone releasing hormone receptor 1.226
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 1.226
TGFB2 transforming growth factor, beta 2 1.225
AXIN2 axin 2 1.224
CEP19 centrosomal protein 19kDa 1.223
TRIM32 tripartite motif containing 32 1.222
FGF23 fibroblast growth factor 23 1.219
WDR20 WD repeat domain 20 1.219
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 1.218
CUL7 cullin 7 1.213
CUL4B cullin 4B 1.213
PAEP progestagen-associated endometrial protein 1.211
RABIF RAB interacting factor 1.208
HOXD10 homeobox D10 1.201
MEST mesoderm specific transcript 1.198
CRTAP cartilage associated protein 1.195
NOTCH2 notch 2 1.194
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.193
MEF2C myocyte enhancer factor 2C 1.193
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 1.193
ELN elastin 1.191
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 1.187
MC4R melanocortin 4 receptor 1.187
BMP1 bone morphogenetic protein 1 1.186
BGN biglycan 1.185
MFAP2 microfibrillar-associated protein 2 1.185
PLEKHD1 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 1.185
MEGF8 multiple EGF-like-domains 8 1.185
SF3B4 splicing factor 3b, subunit 4, 49kDa 1.184
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.183
EGF epidermal growth factor 1.182
WNT11 wingless-type MMTV integration site family, member 11 1.181
LEMD3 LEM domain containing 3 1.179
FAM111A family with sequence similarity 111, member A 1.179
PRICKLE2 prickle homolog 2 (Drosophila) 1.177
F3 coagulation factor III (thromboplastin, tissue factor) 1.175
DCN decorin 1.173
PAX9 paired box 9 1.172
SMAD3 SMAD family member 3 1.172
FGF2 fibroblast growth factor 2 (basic) 1.171
ALPL alkaline phosphatase, liver/bone/kidney 1.171
CCDC126 coiled-coil domain containing 126 1.17
EXTL1 exostosin-like glycosyltransferase 1 1.169
WNT3 wingless-type MMTV integration site family, member 3 1.169
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 1.167
TBX4 T-box 4 1.165
SALL1 spalt-like transcription factor 1 1.164
H2BC21 H2B clustered histone 21 1.164
PIGW phosphatidylinositol glycan anchor biosynthesis, class W 1.164
SMAD2 SMAD family member 2 1.163
CASR calcium-sensing receptor 1.163
GDF2 growth differentiation factor 2 1.162
DLX1 distal-less homeobox 1 1.157
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.155
TCTN1 tectonic family member 1 1.155
BHLHA9 basic helix-loop-helix family, member a9 1.154
CTSK cathepsin K 1.154
F10 coagulation factor X 1.153
PGAP2 post-GPI attachment to proteins 2 1.153
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 1.152
FBLN1 fibulin 1 1.149
TBL1X transducin (beta)-like 1X-linked 1.149
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22 1.149
ACVR2A activin A receptor, type IIA 1.149
TRAPPC2 trafficking protein particle complex 2 1.147
HDAC1 histone deacetylase 1 1.146
WNT10A wingless-type MMTV integration site family, member 10A 1.146
BICRA BRD4 interacting chromatin remodeling complex associated protein 1.144
PGAP3 post-GPI attachment to proteins 3 1.144
TBC1D24 TBC1 domain family, member 24 1.144
CCDC8 coiled-coil domain containing 8 1.141
RSPH3 radial spoke 3 homolog (Chlamydomonas) 1.14
CREB1 cAMP responsive element binding protein 1 1.139
KANSL1 KAT8 regulatory NSL complex subunit 1 1.139
IFT57 intraflagellar transport 57 1.138
REN renin 1.137
AXIN1 axin 1 1.134
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16 1.132
SOS1 son of sevenless homolog 1 (Drosophila) 1.131
GATA4 GATA binding protein 4 1.131
CALML6 calmodulin-like 6 1.131
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 1.129
TBX3 T-box 3 1.129
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 1.128
TGDS TDP-glucose 4,6-dehydratase 1.127
THSD4 thrombospondin, type I, domain containing 4 1.126
PHF6 PHD finger protein 6 1.125
RAB8A RAB8A, member RAS oncogene family 1.123
MUSK muscle, skeletal, receptor tyrosine kinase 1.122
FLNB filamin B, beta 1.122
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.122
ALG3 ALG3, alpha-1,3- mannosyltransferase 1.122
HDAC6 histone deacetylase 6 1.121
PLEK2 pleckstrin 2 1.121
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.12
KLHL42 kelch-like family member 42 1.12
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 1.119
CEP83 centrosomal protein 83kDa 1.118
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 1.117
CALML4 calmodulin-like 4 1.117
CALML3 calmodulin-like 3 1.115
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 1.114
CALML5 calmodulin-like 5 1.114
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 1.113
CENPL centromere protein L 1.113
PLEK pleckstrin 1.112
BMP5 bone morphogenetic protein 5 1.11
BMP6 bone morphogenetic protein 6 1.11
CEP152 centrosomal protein 152kDa 1.11
LBX1 ladybird homeobox 1 1.109
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 1.108
IGFALS insulin-like growth factor binding protein, acid labile subunit 1.108
MAGEB16 melanoma antigen family B16 1.107
IGF1R insulin-like growth factor 1 receptor 1.106
SLC10A7 solute carrier family 10, member 7 1.106
WNK4 WNK lysine deficient protein kinase 4 1.106
GALNS galactosamine (N-acetyl)-6-sulfatase 1.106
MBOAT1 membrane bound O-acyltransferase domain containing 1 1.106
FN1 fibronectin 1 1.105
STPG2 sperm-tail PG-rich repeat containing 2 1.105
ACVR2B activin A receptor, type IIB 1.105
ZCCHC9 zinc finger, CCHC domain containing 9 1.104
PPOX protoporphyrinogen oxidase 1.104
IFT46 intraflagellar transport 46 1.103
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 1.103
GAS1 growth arrest-specific 1 1.102
CDC42 cell division cycle 42 1.102
TGFB3 transforming growth factor, beta 3 1.099
RBM27 RNA binding motif protein 27 1.099
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.096
TUBGCP5 tubulin, gamma complex associated protein 5 1.096
CEP63 centrosomal protein 63kDa 1.093
SCX scleraxis basic helix-loop-helix transcription factor 1.093
PLAGL1 pleiomorphic adenoma gene-like 1 1.092
CPA6 carboxypeptidase A6 1.092
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.091
GH1 growth hormone 1 1.091
DLK1 delta-like 1 homolog (Drosophila) 1.091
GCM2 glial cells missing homolog 2 (Drosophila) 1.088
MRTFA myocardin related transcription factor A 1.088
FZD5 frizzled class receptor 5 1.086
PHF21A PHD finger protein 21A 1.086
IFT22 intraflagellar transport 22 1.086
SOX3 SRY (sex determining region Y)-box 3 1.086
GRB10 growth factor receptor-bound protein 10 1.085
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.085
GLB1 galactosidase, beta 1 1.084
CAPN10 calpain 10 1.084
LHX9 LIM homeobox 9 1.083
IBSP integrin-binding sialoprotein 1.083
KAT6A K(lysine) acetyltransferase 6A 1.081
EFTUD2 elongation factor Tu GTP binding domain containing 2 1.08
RHOA ras homolog family member A 1.079
HOXD1 homeobox D1 1.079
CFAP410 cilia and flagella associated protein 410 1.073
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 1.072
OSR2 odd-skipped related transciption factor 2 1.071
GPR35 G protein-coupled receptor 35 1.071
HDAC2 histone deacetylase 2 1.07
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.069
BMPER BMP binding endothelial regulator 1.065
HNRNPR heterogeneous nuclear ribonucleoprotein R 1.064
DEAF1 DEAF1 transcription factor 1.063
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 1.063
HNF4A hepatocyte nuclear factor 4, alpha 1.062
PPP1R12C protein phosphatase 1, regulatory subunit 12C 1.061
IPO8 importin 8 1.06
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 1.06
TGM1 transglutaminase 1 1.059
ARL6 ADP-ribosylation factor-like 6 1.059
SATB2 SATB homeobox 2 1.056
KIF22 kinesin family member 22 1.055
RAE1 ribonucleic acid export 1 1.055
NALCN sodium leak channel, non selective 1.055
UBE3A ubiquitin protein ligase E3A 1.054
NRXN1 neurexin 1 1.054
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 1.053
KIF26B kinesin family member 26B 1.053
NOTCH1 notch 1 1.052
PKD1 polycystic kidney disease 1 (autosomal dominant) 1.051
RPGR retinitis pigmentosa GTPase regulator 1.05
TMEM165 transmembrane protein 165 1.05
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.049
HDAC5 histone deacetylase 5 1.049
NEK9 NIMA-related kinase 9 1.047
LGALS4 lectin, galactoside-binding, soluble, 4 1.047
WNT8A wingless-type MMTV integration site family, member 8A 1.047
KIF24 kinesin family member 24 1.045
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 1.042
HDAC3 histone deacetylase 3 1.041
ZIC2 Zic family member 2 1.04
EN1 engrailed homeobox 1 1.039
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 1.038
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 1.038
TRAPPC2L trafficking protein particle complex 2-like 1.037
SNX13 sorting nexin 13 1.037
LHX1 LIM homeobox 1 1.036
EXTL2 exostosin-like glycosyltransferase 2 1.036
DLL4 delta-like 4 (Drosophila) 1.035
CTCFL CCCTC-binding factor (zinc finger protein)-like 1.034
MEF2A myocyte enhancer factor 2A 1.033
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.033
GJA1 gap junction protein, alpha 1, 43kDa 1.032
MKRN3 makorin ring finger protein 3 1.032
TP53 tumor protein p53 1.031
NIPAL4 NIPA-like domain containing 4 1.03
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 1.03
COL5A1 collagen, type V, alpha 1 1.03
LMX1B LIM homeobox transcription factor 1, beta 1.029
RHO rhodopsin 1.029
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.027
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.026
TMEM107 transmembrane protein 107 1.026
ZNF699 zinc finger protein 699 1.025
DMRTB1 DMRT-like family B with proline-rich C-terminal, 1 1.024
POU5F1 POU class 5 homeobox 1 1.024
ACTL6A actin-like 6A 1.024
BDNF brain-derived neurotrophic factor 1.023
KDM5C lysine (K)-specific demethylase 5C 1.023
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 1.023
JUN jun proto-oncogene 1.022
PITX3 paired-like homeodomain 3 1.022
SGSH N-sulfoglucosamine sulfohydrolase 1.022
LBR lamin B receptor 1.02
EXOSC2 exosome component 2 1.02
ZBED3 zinc finger, BED-type containing 3 1.019
PKD2 polycystic kidney disease 2 (autosomal dominant) 1.019
MIA3 melanoma inhibitory activity family, member 3 1.018
D2HGDH D-2-hydroxyglutarate dehydrogenase 1.018
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 1.014
WNT5B wingless-type MMTV integration site family, member 5B 1.014
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 1.013
DAAM1 dishevelled associated activator of morphogenesis 1 1.013
AP2M1 adaptor-related protein complex 2, mu 1 subunit 1.013
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 1.012
HDAC11 histone deacetylase 11 1.01
PORCN porcupine homolog (Drosophila) 1.01
PIGO phosphatidylinositol glycan anchor biosynthesis, class O 1.007
JAG2 jagged 2 1.006
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 1.006
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 1.006
ZIC1 Zic family member 1 1.006
H2AC20 H2A clustered histone 20 1.004
H2AC18 H2A clustered histone 18 1.002
PRPF31 pre-mRNA processing factor 31 1.002
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 1.002
COL3A1 collagen, type III, alpha 1 1.0