Brain Infarction Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D020520
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Genes

164 genes/proteins associated with the disease Brain Infarction from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
FGF2 fibroblast growth factor 2 (basic) 2.88009
SIRT1 sirtuin 1 2.88009
CYBB cytochrome b-245, beta polypeptide 2.88009
GPR17 G protein-coupled receptor 17 2.88009
PLAT plasminogen activator, tissue 2.88009
BAX BCL2-associated X protein 2.13069
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.05595
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.94738
BCL2 B-cell CLL/lymphoma 2 1.92626
CAT catalase 1.91301
TNF tumor necrosis factor 1.91017
MAPK1 mitogen-activated protein kinase 1 1.88126
JUN jun proto-oncogene 1.81756
IL6 interleukin 6 1.81149
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.78227
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.77743
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.76791
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.7623
MAPK3 mitogen-activated protein kinase 3 1.75162
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.72384
COL1A1 collagen, type I, alpha 1 1.67654
CCL2 chemokine (C-C motif) ligand 2 1.67441
ACTA2 actin, alpha 2, smooth muscle, aorta 1.67137
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.66943
PARP1 poly (ADP-ribose) polymerase 1 1.64101
IFNG interferon, gamma 1.61736
NOS2 nitric oxide synthase 2, inducible 1.60547
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.60314
FOS FBJ murine osteosarcoma viral oncogene homolog 1.59567
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.59241
CXCL8 chemokine (C-X-C motif) ligand 8 1.58374
VEGFA vascular endothelial growth factor A 1.56558
SOD2 superoxide dismutase 2, mitochondrial 1.5555
EGR1 early growth response 1 1.55108
IL1B interleukin 1, beta 1.53407
TP53 tumor protein p53 1.53258
HMOX1 heme oxygenase 1 1.53184
MMP9 matrix metallopeptidase 9 1.51835
GSK3B glycogen synthase kinase 3 beta 1.5123
MMP2 matrix metallopeptidase 2 1.50852
TGFB1 transforming growth factor, beta 1 1.50043
MAPK8 mitogen-activated protein kinase 8 1.49356
FASLG Fas ligand (TNF superfamily, member 6) 1.49019
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.46701
CCND1 cyclin D1 1.46542
BCL2L1 BCL2-like 1 1.46251
F3 coagulation factor III (thromboplastin, tissue factor) 1.46015
IL10 interleukin 10 1.45405
ICAM1 intercellular adhesion molecule 1 1.4449
DIABLO diablo, IAP-binding mitochondrial protein 1.44273
BECN1 beclin 1, autophagy related 1.43591
COL1A2 collagen, type I, alpha 2 1.43239
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.41202
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.39086
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.36161
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.36161
VCAM1 vascular cell adhesion molecule 1 1.35906
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.35676
CFLAR CASP8 and FADD-like apoptosis regulator 1.35647
SOD1 superoxide dismutase 1, soluble 1.35415
CCND3 cyclin D3 1.35127
PECAM1 platelet/endothelial cell adhesion molecule 1 1.34459
PCNA proliferating cell nuclear antigen 1.34111
CXCL10 chemokine (C-X-C motif) ligand 10 1.34082
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.33938
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.33791
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.33612
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.33199
FAS Fas cell surface death receptor 1.3314
CCNA2 cyclin A2 1.32726
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.31837
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.31506
MAPK14 mitogen-activated protein kinase 14 1.31148
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.30117
BDNF brain-derived neurotrophic factor 1.30087
PPARG peroxisome proliferator-activated receptor gamma 1.29875
GFAP glial fibrillary acidic protein 1.29379
GPX1 glutathione peroxidase 1 1.29379
F2 coagulation factor II (thrombin) 1.29103
NOS3 nitric oxide synthase 3 (endothelial cell) 1.29103
IL4 interleukin 4 1.2895
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.2772
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.27689
CASP12 caspase 12 (gene/pseudogene) 1.26669
BIRC5 baculoviral IAP repeat containing 5 1.26483
MAP2K1 mitogen-activated protein kinase kinase 1 1.26267
PTEN phosphatase and tensin homolog 1.25121
GJA1 gap junction protein, alpha 1, 43kDa 1.24496
MCL1 myeloid cell leukemia 1 1.2368
RB1 retinoblastoma 1 1.23424
GSTP1 glutathione S-transferase pi 1 1.23392
BBC3 BCL2 binding component 3 1.22916
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.22821
CYBA cytochrome b-245, alpha polypeptide 1.22758
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.22566
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.22469
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.22242
BIRC2 baculoviral IAP repeat containing 2 1.21887
CD40LG CD40 ligand 1.21337
NFE2L2 nuclear factor, erythroid 2-like 2 1.21304
EDN1 endothelin 1 1.199
CDK2 cyclin-dependent kinase 2 1.18718
E2F1 E2F transcription factor 1 1.1862
EIF4E eukaryotic translation initiation factor 4E 1.18391
ATF3 activating transcription factor 3 1.18293
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.18193
EGFR epidermal growth factor receptor 1.17101
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.169
CDK1 cyclin-dependent kinase 1 1.16302
IL4R interleukin 4 receptor 1.16203
S100A4 S100 calcium binding protein A4 1.14438
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.14302
TIMP1 TIMP metallopeptidase inhibitor 1 1.142
HBA1 hemoglobin, alpha 1 1.13689
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.13586
ATF2 activating transcription factor 2 1.13552
LMNA lamin A/C 1.12737
FSHB follicle stimulating hormone, beta polypeptide 1.12461
TAGLN transgelin 1.11536
H2AFX H2A histone family, member X 1.1122
IL18 interleukin 18 1.1122
IRF9 interferon regulatory factor 9 1.11081
BAD BCL2-associated agonist of cell death 1.11081
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.10977
APOE apolipoprotein E 1.10838
FOXO3 forkhead box O3 1.10769
NPPA natriuretic peptide A 1.10388
CALD1 caldesmon 1 1.10353
PDGFB platelet-derived growth factor beta polypeptide 1.08904
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.08549
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.08372
CDK4 cyclin-dependent kinase 4 1.08055
HSPB1 heat shock 27kDa protein 1 1.07732
IL2 interleukin 2 1.07696
PTK2 protein tyrosine kinase 2 1.0766
POR P450 (cytochrome) oxidoreductase 1.07376
LHB luteinizing hormone beta polypeptide 1.07269
TERT telomerase reverse transcriptase 1.06987
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.06661
MPO myeloperoxidase 1.06625
IGF1 insulin-like growth factor 1 (somatomedin C) 1.06479
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.06008
PRL prolactin 1.05864
DDIT3 DNA-damage-inducible transcript 3 1.05793
COL3A1 collagen, type III, alpha 1 1.05349
DRD2 dopamine receptor D2 1.05274
TXNRD1 thioredoxin reductase 1 1.05237
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.05163
TGFB2 transforming growth factor, beta 2 1.05015
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.04721
FN1 fibronectin 1 1.04538
WT1 Wilms tumor 1 1.04014
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.03456
MAPT microtubule-associated protein tau 1.03009
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.02708
FBXO32 F-box protein 32 1.02447
DES desmin 1.02447
CAV1 caveolin 1, caveolae protein, 22kDa 1.0241
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.01852
MMP3 matrix metallopeptidase 3 1.01701
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.01212
IGFBP4 insulin-like growth factor binding protein 4 1.01174
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.01099
LEP leptin 1.01025