Brain Lower Grade Glioma_LGG_TCGA-CS-4942-01A-01R-1470-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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348 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-CS-4942-01A-01R-1470-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ABT1 activator of basal transcription 1
ACTRT2 actin-related protein T2
ADCY7 adenylate cyclase 7
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADNP2 ADNP homeobox 2
ADORA2A adenosine A2a receptor
ADORA3 adenosine A3 receptor
AFF2 AF4/FMR2 family, member 2
AGO1 argonaute RISC catalytic component 1
AMBN ameloblastin (enamel matrix protein)
ANGPTL6 angiopoietin-like 6
ANKRD30BL ankyrin repeat domain 30B-like
ANKRD34B ankyrin repeat domain 34B
ANO3 anoctamin 3
ANTXR1 anthrax toxin receptor 1
AOAH acyloxyacyl hydrolase (neutrophil)
APOC1P1 apolipoprotein C-I pseudogene 1
ARHGAP12 Rho GTPase activating protein 12
ARL2BP ADP-ribosylation factor-like 2 binding protein
AXL AXL receptor tyrosine kinase
BTK Bruton agammaglobulinemia tyrosine kinase
BTN3A1 butyrophilin, subfamily 3, member A1
BTN3A2 butyrophilin, subfamily 3, member A2
C10ORF107 chromosome 10 open reading frame 107
C11ORF45 chromosome 11 open reading frame 45
C16ORF54 chromosome 16 open reading frame 54
C19ORF38 chromosome 19 open reading frame 38
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C22ORF42 chromosome 22 open reading frame 42
C7ORF25 chromosome 7 open reading frame 25
C8A complement component 8, alpha polypeptide
CASC3 cancer susceptibility candidate 3
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC97 coiled-coil domain containing 97
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD180 CD180 molecule
CD4 CD4 molecule
CD48 CD48 molecule
CD53 CD53 molecule
CD84 CD84 molecule
CD86 CD86 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDYL chromodomain protein, Y-like
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CEP41 centrosomal protein 41kDa
CLEC9A C-type lectin domain family 9, member A
CLECL1 C-type lectin-like 1
CLIP2 CAP-GLY domain containing linker protein 2
CNGA1 cyclic nucleotide gated channel alpha 1
COCH cochlin
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CSNK1A1L casein kinase 1, alpha 1-like
CTNND2 catenin (cadherin-associated protein), delta 2
CTSO cathepsin O
CTSS cathepsin S
CXCL16 chemokine (C-X-C motif) ligand 16
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAAM2 dishevelled associated activator of morphogenesis 2
DCAF8L2 DDB1 and CUL4 associated factor 8-like 2
DCBLD1 discoidin, CUB and LCCL domain containing 1
DCK deoxycytidine kinase
DCLRE1B DNA cross-link repair 1B
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFB134 defensin, beta 134
DFNA5 deafness, autosomal dominant 5
DGKB diacylglycerol kinase, beta 90kDa
DLL3 delta-like 3 (Drosophila)
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DOCK2 dedicator of cytokinesis 2
DRD2 dopamine receptor D2
DSG4 desmoglein 4
EDARADD EDAR-associated death domain
EDNRB endothelin receptor type B
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF4H eukaryotic translation initiation factor 4H
ELMO1 engulfment and cell motility 1
ENKUR enkurin, TRPC channel interacting protein
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPSTI1 epithelial stromal interaction 1 (breast)
EVI2B ecotropic viral integration site 2B
EXOC2 exocyst complex component 2
EXOC4 exocyst complex component 4
EYA1 EYA transcriptional coactivator and phosphatase 1
FAM105A family with sequence similarity 105, member A
FAM188B family with sequence similarity 188, member B
FAM78A family with sequence similarity 78, member A
FAM92A1P2 family with sequence similarity 92, member A3
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial
FBXO6 F-box protein 6
FCGBP Fc fragment of IgG binding protein
FGL2 fibrinogen-like 2
FLJ44635 TPT1-like protein
FOXK1 forkhead box K1
FUNDC2P2 FUN14 domain containing 2 pseudogene 2
FYB FYN binding protein
GCC1 GRIP and coiled-coil domain containing 1
GIMAP2 GTPase, IMAP family member 2
GML glycosylphosphatidylinositol anchored molecule like
GNL1 guanine nucleotide binding protein-like 1
GOLGA8CP golgin A8 family, member C, pseudogene
GOLGA8EP golgin A8 family, member E, pseudogene
GOLGA8G golgin A8 family, member G
GPR149 G protein-coupled receptor 149
GPR34 G protein-coupled receptor 34
GPR45 G protein-coupled receptor 45
GPR52 G protein-coupled receptor 52
GPR6 G protein-coupled receptor 6
GPR65 G protein-coupled receptor 65
GPR88 G protein-coupled receptor 88
GPRIN3 GPRIN family member 3
GPSM3 G-protein signaling modulator 3
GSDMA gasdermin A
GSDMC gasdermin C
GUCY2F guanylate cyclase 2F, retinal
HAVCR2 hepatitis A virus cellular receptor 2
HCG18 HLA complex group 18 (non-protein coding)
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HECA headcase homolog (Drosophila)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HLA-A major histocompatibility complex, class I, A
HLA-C major histocompatibility complex, class I, C
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-E major histocompatibility complex, class I, E
HMGN4 high mobility group nucleosomal binding domain 4
HNMT histamine N-methyltransferase
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HOXD8 homeobox D8
HRH4 histamine receptor H4
HSP90AB2P heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
HSP90B3P heat shock protein 90kDa beta (Grp94), member 3, pseudogene
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene)
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGBP1P1 immunoglobulin (CD79A) binding protein 1 pseudogene 1
IGFBPL1 insulin-like growth factor binding protein-like 1
IL12RB1 interleukin 12 receptor, beta 1
IRF9 interferon regulatory factor 9
ISPD isoprenoid synthase domain containing
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KHDC1 KH homology domain containing 1
KIAA1147 KIAA1147
KLHL24 kelch-like family member 24
KLHL5 kelch-like family member 5
KPRP keratinocyte proline-rich protein
KRTAP5-5 keratin associated protein 5-5
LGALS9 lectin, galactoside-binding, soluble, 9
LHFPL1 lipoma HMGIC fusion partner-like 1
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LIPA lipase A, lysosomal acid, cholesterol esterase
LOC100128164 four and a half LIM domains 1 pseudogene
LOC100130331 POTE ankyrin domain family, member F pseudogene
LOC154449 uncharacterized LOC154449
LOC284441 actin-related protein 2 pseudogene
LOC402644 peptidylprolyl isomerase A (cyclophilin A) pseudogene
LOC646999 akirin 1 pseudogene
LPAR5 lysophosphatidic acid receptor 5
LPCAT2 lysophosphatidylcholine acyltransferase 2
LRRC10B leucine rich repeat containing 10B
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LRRIQ3 leucine-rich repeats and IQ motif containing 3
LY86 lymphocyte antigen 86
LYN LYN proto-oncogene, Src family tyrosine kinase
LYPD6 LY6/PLAUR domain containing 6
MED29 mediator complex subunit 29
MESTIT1 MEST intronic transcript 1, antisense RNA
MORC1 MORC family CW-type zinc finger 1
MORF4 mortality factor 4 (pseudogene)
MYLK4 myosin light chain kinase family, member 4
NAGA N-acetylgalactosaminidase, alpha-
NAPSB napsin B aspartic peptidase, pseudogene
NCKAP1L NCK-associated protein 1-like
NECAP2 NECAP endocytosis associated 2
NLRC4 NLR family, CARD domain containing 4
NPPB natriuretic peptide B
NQO2 NAD(P)H dehydrogenase, quinone 2
NUBPL nucleotide binding protein-like
NUDCD3 NudC domain containing 3
NXPH1 neurexophilin 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR10Q1 olfactory receptor, family 10, subfamily Q, member 1
OR13C9 olfactory receptor, family 13, subfamily C, member 9
OR1E2 olfactory receptor, family 1, subfamily E, member 2
OR2L13 olfactory receptor, family 2, subfamily L, member 13
OR2L2 olfactory receptor, family 2, subfamily L, member 2
OR2L8 olfactory receptor, family 2, subfamily L, member 8 (gene/pseudogene)
OR52A4P olfactory receptor, family 52, subfamily A, member 4, pseudogene
OR52D1 olfactory receptor, family 52, subfamily D, member 1
OR52E2 olfactory receptor, family 52, subfamily E, member 2
OR5B3 olfactory receptor, family 5, subfamily B, member 3
OR6X1 olfactory receptor, family 6, subfamily X, member 1
OR7D2 olfactory receptor, family 7, subfamily D, member 2
P2RY8 purinergic receptor P2Y, G-protein coupled, 8
PA2G4P4 proliferation-associated 2G4 pseudogene 4
PABPC1P2 poly(A) binding protein, cytoplasmic 1 pseudogene 2
PANX3 pannexin 3
PATL2 protein associated with topoisomerase II homolog 2 (yeast)
PAX8 paired box 8
PCDHA9 protocadherin alpha 9
PDE10A phosphodiesterase 10A
PENK proenkephalin
PGPEP1L pyroglutamyl-peptidase I-like
PIGR polymeric immunoglobulin receptor
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLD4 phospholipase D family, member 4
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
POTEE POTE ankyrin domain family, member E
POTEF POTE ankyrin domain family, member F
POTEM POTE ankyrin domain family, member M
PPIAL4E peptidylprolyl isomerase A (cyclophilin A)-like 4E
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP1R2P1 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 1
PPT1 palmitoyl-protein thioesterase 1
PPY2P pancreatic polypeptide 2, pseudogene
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PRR34 proline rich 34
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTAFR platelet-activating factor receptor
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RASD2 RASD family, member 2
RASL10B RAS-like, family 10, member B
RCSD1 RCSD domain containing 1
REC114 REC114 meiotic recombination protein
RET ret proto-oncogene
RGS14 regulator of G-protein signaling 14
RGS18 regulator of G-protein signaling 18
RGS19 regulator of G-protein signaling 19
RHCE Rh blood group, CcEe antigens
RNF216 ring finger protein 216
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
RPL19P12 ribosomal protein L19 pseudogene 12
RPS26P11 ribosomal protein S26 pseudogene 11
RRAGD Ras-related GTP binding D
RSG1 REM2 and RAB-like small GTPase 1
RXRG retinoid X receptor, gamma
SAMD9 sterile alpha motif domain containing 9
SBF1P1 SET binding factor 1 pseudogene 1
SCGB1C1 secretoglobin, family 1C, member 1
SCIMP SLP adaptor and CSK interacting membrane protein
SCIN scinderin
SCN4B sodium channel, voltage gated, type IV beta subunit
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFT2D2 SFT2 domain containing 2
SGPL1 sphingosine-1-phosphate lyase 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SLA Src-like-adaptor
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SLC7A6OS solute carrier family 7, member 6 opposite strand
SLFN11 schlafen family member 11
SLITRK6 SLIT and NTRK-like family, member 6
SOAT1 sterol O-acyltransferase 1
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPDYE4 speedy/RINGO cell cycle regulator family member E4
SSR1 signal sequence receptor, alpha
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAP1 signal transducing adaptor family member 1
STAT1 signal transducer and activator of transcription 1, 91kDa
SYNDIG1L synapse differentiation inducing 1-like
SYT6 synaptotagmin VI
SYT9 synaptotagmin IX
TAS2R38 taste receptor, type 2, member 38
TCTE1 t-complex-associated-testis-expressed 1
TDRD7 tudor domain containing 7
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TMC1 transmembrane channel-like 1
TMEM156 transmembrane protein 156
TMEM170B transmembrane protein 170B
TMEM176B transmembrane protein 176B
TMEM41A transmembrane protein 41A
TMEM52B transmembrane protein 52B
TMEM86A transmembrane protein 86A
TMPRSS6 transmembrane protease, serine 6
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TPK1 thiamin pyrophosphokinase 1
TRIL TLR4 interactor with leucine-rich repeats
TRIM25 tripartite motif containing 25
TRIM42 tripartite motif containing 42
TRIM64 tripartite motif containing 64
TSPAN33 tetraspanin 33
TTC30B tetratricopeptide repeat domain 30B
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UBD ubiquitin D
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
ULBP1 UL16 binding protein 1
UPP2 uridine phosphorylase 2
UTS2B urotensin 2B
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
WBP11P1 WW domain binding protein 11 pseudogene 1
WBSCR27 Williams Beuren syndrome chromosome region 27
WDR81 WD repeat domain 81
WDR87 WD repeat domain 87
ZDHHC4 zinc finger, DHHC-type containing 4
ZFAND4 zinc finger, AN1-type domain 4
ZFP82 ZFP82 zinc finger protein
ZIC4 Zic family member 4
ZNF260 zinc finger protein 260
ZNF420 zinc finger protein 420
ZNF503-AS2 ZNF503 antisense RNA 2
ZNF568 zinc finger protein 568
ZNF780A zinc finger protein 780A
ZNF790 zinc finger protein 790
ZNF792 zinc finger protein 792
ZNF853 zinc finger protein 853
ZNF90 zinc finger protein 90
ZSCAN23 zinc finger and SCAN domain containing 23

low expression

Symbol Name
ATG14 autophagy related 14
ATXN3 ataxin 3
BAG5 BCL2-associated athanogene 5
CLK2 CDC-like kinase 2
CREBZF CREB/ATF bZIP transcription factor
EP400NL EP400 N-terminal like
FKBP3 FK506 binding protein 3, 25kDa
KIAA0907 KIAA0907
KLHDC2 kelch domain containing 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MED6 mediator complex subunit 6
NXF1 nuclear RNA export factor 1
PRPF39 pre-mRNA processing factor 39
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
RBM39 RNA binding motif protein 39
REV1 REV1, polymerase (DNA directed)
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)