Brain Lower Grade Glioma_LGG_TCGA-DB-A4XF-01A-11R-A27Q-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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287 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DB-A4XF-01A-11R-A27Q-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADACL4 arylacetamide deacetylase-like 4
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ABI3BP ABI family, member 3 (NESH) binding protein
ACO2 aconitase 2, mitochondrial
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALS2CL ALS2 C-terminal like
ANGPTL3 angiopoietin-like 3
APCDD1 adenomatosis polyposis coli down-regulated 1
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARID5B AT rich interactive domain 5B (MRF1-like)
ARSI arylsulfatase family, member I
ASTN2 astrotactin 2
ATG13 autophagy related 13
BAIAP2 BAI1-associated protein 2
BAIAP3 BAI1-associated protein 3
BARD1 BRCA1 associated RING domain 1
BBS10 Bardet-Biedl syndrome 10
BCL2 B-cell CLL/lymphoma 2
BMPR1B bone morphogenetic protein receptor, type IB
BTBD11 BTB (POZ) domain containing 11
C15ORF52 chromosome 15 open reading frame 52
C17ORF80 chromosome 17 open reading frame 80
C1ORF198 chromosome 1 open reading frame 198
C4A complement component 4A (Rodgers blood group)
C8ORF4 chromosome 8 open reading frame 4
CAB39L calcium binding protein 39-like
CADPS Ca++-dependent secretion activator
CASZ1 castor zinc finger 1
CATSPER4 cation channel, sperm associated 4
CAV1 caveolin 1, caveolae protein, 22kDa
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCDC105 coiled-coil domain containing 105
CCDC136 coiled-coil domain containing 136
CCDC47 coiled-coil domain containing 47
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CDSN corneodesmosin
CENPC centromere protein C
CEP120 centrosomal protein 120kDa
CEP70 centrosomal protein 70kDa
CERS6 ceramide synthase 6
CHSY3 chondroitin sulfate synthase 3
CLSTN2 calsyntenin 2
CLTC clathrin, heavy chain (Hc)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRYAB crystallin, alpha B
CST9 cystatin 9 (testatin)
CST9L cystatin 9-like
DAAM1 dishevelled associated activator of morphogenesis 1
DCLK1 doublecortin-like kinase 1
DCT dopachrome tautomerase
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DEFB132 defensin, beta 132
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNER delta/notch-like EGF repeat containing
EDN1 endothelin 1
EDN3 endothelin 3
EDNRA endothelin receptor type A
EEA1 early endosome antigen 1
EGF epidermal growth factor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELF1 E74-like factor 1 (ets domain transcription factor)
EPHA4 EPH receptor A4
FAM122B family with sequence similarity 122B
FAM169A family with sequence similarity 169, member A
FAM212B family with sequence similarity 212, member B
FASTKD5 FAST kinase domains 5
FBXO31 F-box protein 31
FBXO32 F-box protein 32
FHL1 four and a half LIM domains 1
FILIP1L filamin A interacting protein 1-like
FLJ41941 uncharacterized LOC100192420
FNIP1 folliculin interacting protein 1
FNIP2 folliculin interacting protein 2
FOLR3 folate receptor 3 (gamma)
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FRMD5 FERM domain containing 5
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAL3ST2 galactose-3-O-sulfotransferase 2
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15
GFRA2 GDNF family receptor alpha 2
GJA3 gap junction protein, alpha 3, 46kDa
GLIS3 GLIS family zinc finger 3
GOLIM4 golgi integral membrane protein 4
GPC6 glypican 6
GTSF1L gametocyte specific factor 1-like
GUSBP2 glucuronidase, beta pseudogene 2
H3F3B H3 histone, family 3B (H3.3B)
H3F3C H3 histone, family 3C
HEATR5A HEAT repeat containing 5A
HELQ helicase, POLQ-like
HRH1 histamine receptor H1
HYPM huntingtin interacting protein M
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFNA8 interferon, alpha 8
IKZF2 IKAROS family zinc finger 2 (Helios)
IPO9 importin 9
IRF6 interferon regulatory factor 6
JADE1 jade family PHD finger 1
JAK1 Janus kinase 1
KANSL3 KAT8 regulatory NSL complex subunit 3
KATNAL1 katanin p60 subunit A-like 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCTD9 potassium channel tetramerization domain containing 9
KIAA0355 KIAA0355
KRT32 keratin 32, type I
LCE1E late cornified envelope 1E
LENEP lens epithelial protein
LHB luteinizing hormone beta polypeptide
LINC00596 long intergenic non-protein coding RNA 596
LOC100128076 protein tyrosine phosphatase pseudogene
LOC100134868 uncharacterized LOC100134868
LOC340074 uncharacterized LOC340074
LOC494141 solute carrier family 25, member 51 pseudogene
LOC643923 uncharacterized LOC643923
LOC647859 occludin pseudogene
LOC728024 chromosome X open reading frame 56 pseudogene
LOC90246 uncharacterized LOC90246
LRRC2 leucine rich repeat containing 2
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
LRRIQ3 leucine-rich repeats and IQ motif containing 3
LYRM2 LYR motif containing 2
LYST lysosomal trafficking regulator
MAP10 microtubule-associated protein 10
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MFSD11 major facilitator superfamily domain containing 11
MKL1 megakaryoblastic leukemia (translocation) 1
MKL2 MKL/myocardin-like 2
MKX mohawk homeobox
MREG melanoregulin
MROH2B maestro heat-like repeat family member 2B
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTMR11 myotubularin related protein 11
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NRP2 neuropilin 2
NSG1 neuron specific gene family member 1
NT5DC3 5'-nucleotidase domain containing 3
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
NUDT9P1 nudix (nucleoside diphosphate linked moiety X)-type motif 9 pseudogene 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR2M1P olfactory receptor, family 2, subfamily M, member 1 pseudogene
OR2T33 olfactory receptor, family 2, subfamily T, member 33
OR2V2 olfactory receptor, family 2, subfamily V, member 2
OR52N5 olfactory receptor, family 52, subfamily N, member 5
OR8B3 olfactory receptor, family 8, subfamily B, member 3
OSBPL11 oxysterol binding protein-like 11
OSBPL9 oxysterol binding protein-like 9
OXCT1 3-oxoacid CoA transferase 1
OXSR1 oxidative stress responsive 1
PAQR3 progestin and adipoQ receptor family member III
PCDHA13 protocadherin alpha 13
PCDHB5 protocadherin beta 5
PCDHGA10 protocadherin gamma subfamily A, 10
PCGF5 polycomb group ring finger 5
PDE8B phosphodiesterase 8B
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PNPLA8 patatin-like phospholipase domain containing 8
PPAP2A phosphatidic acid phosphatase type 2A
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRMT9 protein arginine methyltransferase 9
PROS1 protein S (alpha)
PRR16 proline rich 16
PRUNE2 prune homolog 2 (Drosophila)
PTGDR prostaglandin D2 receptor (DP)
PTPDC1 protein tyrosine phosphatase domain containing 1
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PXYLP1 2-phosphoxylose phosphatase 1
RAB4A RAB4A, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBMXL1 RNA binding motif protein, X-linked-like 1
RBMXL3 RNA binding motif protein, X-linked-like 3
RIC8B RIC8 guanine nucleotide exchange factor B
RNFT1 ring finger protein, transmembrane 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPTOR regulatory associated protein of MTOR, complex 1
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SAXO2 stabilizer of axonemal microtubules 2
SDPR serum deprivation response
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SENP7 SUMO1/sentrin specific peptidase 7
SEPN1 selenoprotein N, 1
SEPT9 septin 9
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SH3RF1 SH3 domain containing ring finger 1
SIPA1L2 signal-induced proliferation-associated 1 like 2
SKA2 spindle and kinetochore associated complex subunit 2
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC26A11 solute carrier family 26 (anion exchanger), member 11
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMC5 structural maintenance of chromosomes 5
SMCO3 single-pass membrane protein with coiled-coil domains 3
SMG8 SMG8 nonsense mediated mRNA decay factor
SNIP1 Smad nuclear interacting protein 1
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SORBS1 sorbin and SH3 domain containing 1
SPATA12 spermatogenesis associated 12
SPIRE1 spire-type actin nucleation factor 1
SPTSSB serine palmitoyltransferase, small subunit B
STK17B serine/threonine kinase 17b
SUGT1P1 SUGT1 pseudogene 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBCK TBC1 domain containing kinase
TC2N tandem C2 domains, nuclear
TEX36 testis expressed 36
TGFB2 transforming growth factor, beta 2
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TKTL1 transketolase-like 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLK2 tousled-like kinase 2
TMEM100 transmembrane protein 100
TMEM164 transmembrane protein 164
TMEM184C transmembrane protein 184C
TMEM47 transmembrane protein 47
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOB2 transducer of ERBB2, 2
TPRX1 tetra-peptide repeat homeobox 1
TRIM9 tripartite motif containing 9
TTC33 tetratricopeptide repeat domain 33
TTLL5 tubulin tyrosine ligase-like family member 5
UBA2 ubiquitin-like modifier activating enzyme 2
UGCG UDP-glucose ceramide glucosyltransferase
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP26 ubiquitin specific peptidase 26
VEZF1 vascular endothelial zinc finger 1
VN1R10P vomeronasal 1 receptor 10 pseudogene
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
WBP4 WW domain binding protein 4
WBSCR17 Williams-Beuren syndrome chromosome region 17
WDR88 WD repeat domain 88
WLS wntless Wnt ligand secretion mediator
XIST X inactive specific transcript (non-protein coding)
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBED3 zinc finger, BED-type containing 3
ZBTB1 zinc finger and BTB domain containing 1
ZBTB16 zinc finger and BTB domain containing 16
ZBTB5 zinc finger and BTB domain containing 5
ZBTB6 zinc finger and BTB domain containing 6
ZDHHC15 zinc finger, DHHC-type containing 15
ZFYVE1 zinc finger, FYVE domain containing 1
ZIK1 zinc finger protein interacting with K protein 1
ZMYM5 zinc finger, MYM-type 5
ZNF134 zinc finger protein 134
ZNF223 zinc finger protein 223
ZNF267 zinc finger protein 267
ZNF382 zinc finger protein 382
ZNF441 zinc finger protein 441
ZNF548 zinc finger protein 548
ZNF551 zinc finger protein 551
ZNF665 zinc finger protein 665
ZNF701 zinc finger protein 701
ZNF813 zinc finger protein 813
ZNF836 zinc finger protein 836
ZNF845 zinc finger protein 845

low expression

Symbol Name
ANGEL2 angel homolog 2 (Drosophila)
ASB8 ankyrin repeat and SOCS box containing 8
GCSH glycine cleavage system protein H (aminomethyl carrier)
IPW imprinted in Prader-Willi syndrome (non-protein coding)
LTV1 LTV1 ribosome biogenesis factor
MCRS1 microspherule protein 1
MRPL18 mitochondrial ribosomal protein L18
NDN necdin, melanoma antigen (MAGE) family member
PDCD2 programmed cell death 2
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PWARSN Prader Willi/Angelman region RNA, SNRPN neighbor
ZDHHC16 zinc finger, DHHC-type containing 16