Brain Lower Grade Glioma_LGG_TCGA-DB-A75M-01A-11R-A32Q-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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355 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DB-A75M-01A-11R-A32Q-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADACL4 arylacetamide deacetylase-like 4
AAMP angio-associated, migratory cell protein
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCC6P2 ATP-binding cassette, sub-family C, member 6 pseudogene 2
ABHD6 abhydrolase domain containing 6
ACAA1 acetyl-CoA acyltransferase 1
ACO2 aconitase 2, mitochondrial
ACSF2 acyl-CoA synthetase family member 2
ACSM5 acyl-CoA synthetase medium-chain family member 5
ADCY8 adenylate cyclase 8 (brain)
ADD1 adducin 1 (alpha)
AGAP7P ArfGAP with GTPase domain, ankyrin repeat and PH domain 7, pseudogene
AK8 adenylate kinase 8
AKT1S1 AKT1 substrate 1 (proline-rich)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANKDD1A ankyrin repeat and death domain containing 1A
ANO1 anoctamin 1, calcium activated chloride channel
ANXA10 annexin A10
AQP7P3 aquaporin 7 pseudogene 3
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASMTL acetylserotonin O-methyltransferase-like
ATG2A autophagy related 2A
AXIN2 axin 2
BANP BTG3 associated nuclear protein
BTBD11 BTB (POZ) domain containing 11
C12ORF54 chromosome 12 open reading frame 54
C15ORF52 chromosome 15 open reading frame 52
C17ORF99 chromosome 17 open reading frame 99
C19ORF54 chromosome 19 open reading frame 54
C1ORF94 chromosome 1 open reading frame 94
C5ORF38 chromosome 5 open reading frame 38
C5ORF60 chromosome 5 open reading frame 60
C7ORF61 chromosome 7 open reading frame 61
C7ORF66 chromosome 7 open reading frame 66
C9ORF9 chromosome 9 open reading frame 9
CACNG7 calcium channel, voltage-dependent, gamma subunit 7
CAPN1 calpain 1, (mu/I) large subunit
CCAR2 cell cycle and apoptosis regulator 2
CCDC116 coiled-coil domain containing 116
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CDH26 cadherin 26
CDH7 cadherin 7, type 2
CDK11B cyclin-dependent kinase 11B
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CIART circadian associated repressor of transcription
CIB3 calcium and integrin binding family member 3
CLIP2 CAP-GLY domain containing linker protein 2
CLIP3 CAP-GLY domain containing linker protein 3
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COL6A4P2 collagen, type VI, alpha 4 pseudogene 2
COMT catechol-O-methyltransferase
CSNK1D casein kinase 1, delta
CSNK1G2-AS1 CSNK1G2 antisense RNA 1
CSTL1 cystatin-like 1
CT55 cancer/testis antigen 55
CTSH cathepsin H
CUL4A cullin 4A
CYTH2 cytohesin 2
DARS aspartyl-tRNA synthetase
DBP D site of albumin promoter (albumin D-box) binding protein
DCAKD dephospho-CoA kinase domain containing
DCLK2 doublecortin-like kinase 2
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDB1 damage-specific DNA binding protein 1, 127kDa
DEFA6 defensin, alpha 6, Paneth cell-specific
DHRS4 dehydrogenase/reductase (SDR family) member 4
DMWD dystrophia myotonica, WD repeat containing
DTX4 deltex 4, E3 ubiquitin ligase
DUSP27 dual specificity phosphatase 27 (putative)
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1
EIF3IP1 eukaryotic translation initiation factor 3, subunit I pseudogene 1
EIF5B eukaryotic translation initiation factor 5B
ELAC2 elaC ribonuclease Z 2
ELMO2 engulfment and cell motility 2
ERCC5 excision repair cross-complementation group 5
ETNPPL ethanolamine-phosphate phospho-lyase
EWSR1 EWS RNA-binding protein 1
EZR ezrin
FADS2 fatty acid desaturase 2
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM118A family with sequence similarity 118, member A
FAM167A family with sequence similarity 167, member A
FAM171A1 family with sequence similarity 171, member A1
FAM193A family with sequence similarity 193, member A
FAM25A family with sequence similarity 25, member A
FAM3A family with sequence similarity 3, member A
FAM50A family with sequence similarity 50, member A
FAM83H family with sequence similarity 83, member H
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FBRS fibrosin
FBXO44 F-box protein 44
FGF17 fibroblast growth factor 17
FLJ16779 uncharacterized LOC100192386
FOXK1 forkhead box K1
FSTL5 follistatin-like 5
GABARAPL2 GABA(A) receptor-associated protein-like 2
GALR3 galanin receptor 3
GBP7 guanylate binding protein 7
GBX2 gastrulation brain homeobox 2
GDF7 growth differentiation factor 7
GDPGP1 GDP-D-glucose phosphorylase 1
GINS3 GINS complex subunit 3 (Psf3 homolog)
GJA10 gap junction protein, alpha 10, 62kDa
GLIS1 GLIS family zinc finger 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GOLGA6L5P golgin A6 family-like 5, pseudogene
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPKOW G patch domain and KOW motifs
GPR153 G protein-coupled receptor 153
GPRC5B G protein-coupled receptor, class C, group 5, member B
GRAMD4 GRAM domain containing 4
GRIK5 glutamate receptor, ionotropic, kainate 5
GRTP1 growth hormone regulated TBC protein 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTM3 glutathione S-transferase mu 3 (brain)
GUCA1B guanylate cyclase activator 1B (retina)
GUCA2A guanylate cyclase activator 2A (guanylin)
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HHLA1 HERV-H LTR-associating 1
HIST1H2BI histone cluster 1, H2bi
HMGN5 high mobility group nucleosome binding domain 5
HNF1A HNF1 homeobox A
HNRNPL heterogeneous nuclear ribonucleoprotein L
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSP90AB4P heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene
HSPA1L heat shock 70kDa protein 1-like
HTATSF1 HIV-1 Tat specific factor 1
IFNA5 interferon, alpha 5
IFT140 intraflagellar transport 140
IGSF1 immunoglobulin superfamily, member 1
IK IK cytokine, down-regulator of HLA II
IRAK1 interleukin-1 receptor-associated kinase 1
ITGB4 integrin, beta 4
IVL involucrin
KCNRG potassium channel regulator
KCTD11 potassium channel tetramerization domain containing 11
KCTD15 potassium channel tetramerization domain containing 15
KIAA1549 KIAA1549
KIAA2013 KIAA2013
KIF7 kinesin family member 7
KLHDC8B kelch domain containing 8B
KLHL25 kelch-like family member 25
KNOP1 lysine-rich nucleolar protein 1
KRTAP24-1 keratin associated protein 24-1
LAMP1 lysosomal-associated membrane protein 1
LCAT lecithin-cholesterol acyltransferase
LCE1B late cornified envelope 1B
LCE6A late cornified envelope 6A
LCN12 lipocalin 12
LCNL1 lipocalin-like 1
LDOC1 leucine zipper, down-regulated in cancer 1
LINC00244 long intergenic non-protein coding RNA 244
LINC00685 long intergenic non-protein coding RNA 685
LIX1 Lix1 homolog (chicken)
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMOD2 leiomodin 2 (cardiac)
LOC145474 uncharacterized LOC145474
LOC728024 chromosome X open reading frame 56 pseudogene
LOC729609 uncharacterized LOC729609
LPL lipoprotein lipase
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
LTBP3 latent transforming growth factor beta binding protein 3
LTBP4 latent transforming growth factor beta binding protein 4
LUZP2 leucine zipper protein 2
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7D1 MAP7 domain containing 1
MARVELD3 MARVEL domain containing 3
MEGF8 multiple EGF-like-domains 8
MIA2 melanoma inhibitory activity 2
MID1IP1 MID1 interacting protein 1
MOGAT3 monoacylglycerol O-acyltransferase 3
MORN1 MORN repeat containing 1
MRFAP1 Morf4 family associated protein 1
MSX1 msh homeobox 1
MTVR2 mouse mammary tumor virus receptor homolog 2
MUM1 melanoma associated antigen (mutated) 1
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
MYLK4 myosin light chain kinase family, member 4
MYO18A myosin XVIIIA
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NELFA negative elongation factor complex member A
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NINJ1 ninjurin 1
NKAIN4 Na+/K+ transporting ATPase interacting 4
NKAP NFKB activating protein
NKX2-8 NK2 homeobox 8
NMB neuromedin B
NPHP4 nephronophthisis 4
NPVF neuropeptide VF precursor
NR2F1 nuclear receptor subfamily 2, group F, member 1
NUMA1 nuclear mitotic apparatus protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
NYNRIN NYN domain and retroviral integrase containing
OARD1 O-acyl-ADP-ribose deacylase 1
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene)
OR51I2 olfactory receptor, family 51, subfamily I, member 2
OR51M1 olfactory receptor, family 51, subfamily M, member 1
OR52A5 olfactory receptor, family 52, subfamily A, member 5
OR8K1 olfactory receptor, family 8, subfamily K, member 1
OTUD5 OTU deubiquitinase 5
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PANX3 pannexin 3
PARD3 par-3 family cell polarity regulator
PCCA propionyl CoA carboxylase, alpha polypeptide
PCDHB6 protocadherin beta 6
PCDHGB7 protocadherin gamma subfamily B, 7
PCIF1 PDX1 C-terminal inhibiting factor 1
PDDC1 Parkinson disease 7 domain containing 1
PEX10 peroxisomal biogenesis factor 10
PEX14 peroxisomal biogenesis factor 14
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKL phosphofructokinase, liver
PGA3 pepsinogen 3, group I (pepsinogen A)
PHGDH phosphoglycerate dehydrogenase
PLEC plectin
PLXNB1 plexin B1
PMM1 phosphomannomutase 1
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
POM121L10P POM121 transmembrane nucleoporin-like 10, pseudogene
POMT1 protein-O-mannosyltransferase 1
POMT2 protein-O-mannosyltransferase 2
PPAN-P2RY11 PPAN-P2RY11 readthrough
PROCA1 protein interacting with cyclin A1
PROM2 prominin 2
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PRSS42 protease, serine, 42
PRSS54 protease, serine, 54
PSD4 pleckstrin and Sec7 domain containing 4
PTH1R parathyroid hormone 1 receptor
PTK6 protein tyrosine kinase 6
PTPRF protein tyrosine phosphatase, receptor type, F
RAB5C RAB5C, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RANBP3 RAN binding protein 3
RBM17 RNA binding motif protein 17
RGS12 regulator of G-protein signaling 12
RGS9 regulator of G-protein signaling 9
RHBDD3 rhomboid domain containing 3
RNASE8 ribonuclease, RNase A family, 8
RNF183 ring finger protein 183
RSPO3 R-spondin 3
RXRA retinoid X receptor, alpha
RYR1 ryanodine receptor 1 (skeletal)
SAFB2 scaffold attachment factor B2
SALL2 spalt-like transcription factor 2
SAMD11 sterile alpha motif domain containing 11
SCRIB scribbled planar cell polarity protein
SEC1P secretory blood group 1, pseudogene
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SFRP2 secreted frizzled-related protein 2
SH2D3A SH2 domain containing 3A
SH3BGR SH3 domain binding glutamate-rich protein
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIPA1L2 signal-induced proliferation-associated 1 like 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A26 solute carrier family 25 (S-adenosylmethionine carrier), member 26
SLC25A47 solute carrier family 25, member 47
SLC35E4 solute carrier family 35, member E4
SLC36A3 solute carrier family 36, member 3
SLC39A11 solute carrier family 39, member 11
SLC39A5 solute carrier family 39 (zinc transporter), member 5
SLC44A2 solute carrier family 44 (choline transporter), member 2
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMAD6 SMAD family member 6
SMCP sperm mitochondria-associated cysteine-rich protein
SMG6 SMG6 nonsense mediated mRNA decay factor
SNX18 sorting nexin 18
SORBS3 sorbin and SH3 domain containing 3
SP2 Sp2 transcription factor
SPANXC SPANX family, member C
SPEG SPEG complex locus
SPRR4 small proline-rich protein 4
SRRM5 serine/arginine repetitive matrix 5
SRSF4 serine/arginine-rich splicing factor 4
ST5 suppression of tumorigenicity 5
STX18 syntaxin 18
SUOX sulfite oxidase
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SYMPK symplekin
TAAR5 trace amine associated receptor 5
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TAGAP T-cell activation RhoGTPase activating protein
TBC1D17 TBC1 domain family, member 17
TBX10 T-box 10
TCEAL2 transcription elongation factor A (SII)-like 2
TCEAL3 transcription elongation factor A (SII)-like 3
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCP10L t-complex 10-like
TDH L-threonine dehydrogenase (pseudogene)
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
TFDP1 transcription factor Dp-1
TFE3 transcription factor binding to IGHM enhancer 3
TIAM1 T-cell lymphoma invasion and metastasis 1
TJP2 tight junction protein 2
TLE3 transducin-like enhancer of split 3
TMCO3 transmembrane and coiled-coil domains 3
TMEM211 transmembrane protein 211
TMEM95 transmembrane protein 95
TNIP1 TNFAIP3 interacting protein 1
TNK1 tyrosine kinase, non-receptor, 1
TNKS1BP1 tankyrase 1 binding protein 1, 182kDa
TOB2 transducer of ERBB2, 2
TPI1P3 triosephosphate isomerase 1 pseudogene 3
TPTEP1 transmembrane phosphatase with tensin homology pseudogene 1
TRAPPC12 trafficking protein particle complex 12
TRDN triadin
TRIM50 tripartite motif containing 50
TSPAN10 tetraspanin 10
TSSK3 testis-specific serine kinase 3
TTYH1 tweety family member 1
U2AF2 U2 small nuclear RNA auxiliary factor 2
UBAP1 ubiquitin associated protein 1
UBIAD1 UbiA prenyltransferase domain containing 1
UBQLN3 ubiquilin 3
UGT2B11 UDP glucuronosyltransferase 2 family, polypeptide B11
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USF2 upstream transcription factor 2, c-fos interacting
USH1C Usher syndrome 1C (autosomal recessive, severe)
VANGL2 VANGL planar cell polarity protein 2
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
WNK2 WNK lysine deficient protein kinase 2
WNT9B wingless-type MMTV integration site family, member 9B
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZBTB45 zinc finger and BTB domain containing 45
ZC3H18 zinc finger CCCH-type containing 18
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC18 zinc finger, CCHC domain containing 18
ZDHHC3 zinc finger, DHHC-type containing 3
ZIM3 zinc finger, imprinted 3
ZNF213 zinc finger protein 213
ZNF296 zinc finger protein 296
ZNF438 zinc finger protein 438
ZNF444 zinc finger protein 444
ZNF826P zinc finger protein 826, pseudogene
ZSCAN18 zinc finger and SCAN domain containing 18

low expression

Symbol Name
BTBD1 BTB (POZ) domain containing 1
FBXO48 F-box protein 48
GID4 GID complex subunit 4
TMEM182 transmembrane protein 182