Brain Lower Grade Glioma_LGG_TCGA-DU-5855-01A-11R-1708-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
Similar Terms
Downloads & Tools


286 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DU-5855-01A-11R-1708-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ABLIM1 actin binding LIM protein 1
ACAD8 acyl-CoA dehydrogenase family, member 8
ACPP acid phosphatase, prostate
ACTB actin, beta
ACY3 aminoacylase 3
ADAM7 ADAM metallopeptidase domain 7
ADGRG4 adhesion G protein-coupled receptor G4
ADGRG5 adhesion G protein-coupled receptor G5
ADGRG7 adhesion G protein-coupled receptor G7
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ADRA1D adrenoceptor alpha 1D
AIM1L absent in melanoma 1-like
AJAP1 adherens junctions associated protein 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AMOTL1 angiomotin like 1
ANGPT4 angiopoietin 4
ANKRD13A ankyrin repeat domain 13A
ANKRD49 ankyrin repeat domain 49
AQP2 aquaporin 2 (collecting duct)
AR androgen receptor
ARCN1 archain 1
ARHGAP32 Rho GTPase activating protein 32
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase
ATF3 activating transcription factor 3
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
BAHCC1 BAH domain and coiled-coil containing 1
BCAS3 breast carcinoma amplified sequence 3
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BCL9L B-cell CLL/lymphoma 9-like
BTG2 BTG family, member 2
BUD13 BUD13 homolog (S. cerevisiae)
C11ORF52 chromosome 11 open reading frame 52
C15ORF52 chromosome 15 open reading frame 52
CA5A carbonic anhydrase VA, mitochondrial
CAB39L calcium binding protein 39-like
CADM1 cell adhesion molecule 1
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC144B coiled-coil domain containing 144B (pseudogene)
CCDC172 coiled-coil domain containing 172
CCL3 chemokine (C-C motif) ligand 3
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCL8 chemokine (C-C motif) ligand 8
CD69 CD69 molecule
CDC14A cell division cycle 14A
CDK15 cyclin-dependent kinase 15
CDV3 CDV3 homolog (mouse)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEP164 centrosomal protein 164kDa
CFL2 cofilin 2 (muscle)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLDN25 claudin 25
CLDN8 claudin 8
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
CRYAB crystallin, alpha B
CRYGB crystallin, gamma B
CRYGC crystallin, gamma C
CSPG4 chondroitin sulfate proteoglycan 4
CTTNBP2 cortactin binding protein 2
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DISP1 dispatched homolog 1 (Drosophila)
DNASE2B deoxyribonuclease II beta
DSCAML1 Down syndrome cell adhesion molecule like 1
DSPP dentin sialophosphoprotein
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EHF ets homologous factor
ELF1 E74-like factor 1 (ets domain transcription factor)
ENAM enamelin
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXOC6B exocyst complex component 6B
EXOSC6 exosome component 6
FAM106A family with sequence similarity 106, member A
FAM13C family with sequence similarity 13, member C
FAM157A family with sequence similarity 157, member A
FAM214A family with sequence similarity 214, member A
FBXO32 F-box protein 32
FFAR3 free fatty acid receptor 3
FOLR3 folate receptor 3 (gamma)
FSTL3 follistatin-like 3 (secreted glycoprotein)
FXYD6 FXYD domain containing ion transport regulator 6
G6PD glucose-6-phosphate dehydrogenase
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GHRL ghrelin/obestatin prepropeptide
GLB1L2 galactosidase, beta 1-like 2
GLIS1 GLIS family zinc finger 1
GPR132 G protein-coupled receptor 132
GPX3 glutathione peroxidase 3
GSG1L GSG1-like
H2AFV H2A histone family, member V
HINFP histone H4 transcription factor
HLX H2.0-like homeobox
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HYOU1 hypoxia up-regulated 1
IFT46 intraflagellar transport 46
IL19 interleukin 19
IL1B interleukin 1, beta
IL31RA interleukin 31 receptor A
IQGAP2 IQ motif containing GTPase activating protein 2
IRS1 insulin receptor substrate 1
ISX intestine-specific homeobox
ITGA8 integrin, alpha 8
JAK1 Janus kinase 1
JAM3 junctional adhesion molecule 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KLHL21 kelch-like family member 21
KLK2 kallikrein-related peptidase 2
KLK3 kallikrein-related peptidase 3
KLK4 kallikrein-related peptidase 4
KMT2A lysine (K)-specific methyltransferase 2A
KRT32 keratin 32, type I
KRT34 keratin 34, type I
KRTAP4-12 keratin associated protein 4-12
KRTAP4-3 keratin associated protein 4-3
LOC285847 uncharacterized LOC285847
LOC644936 actin, beta pseudogene
LOC728989 phosphodiesterase 4D interacting protein pseudogene
LRRC28 leucine rich repeat containing 28
MAGEA5 melanoma antigen family A5
MAP3K7CL MAP3K7 C-terminal like
MED13L mediator complex subunit 13-like
MEF2A myocyte enhancer factor 2A
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MRGPRD MAS-related GPR, member D
MROH9 maestro heat-like repeat family member 9
MSMB microseminoprotein, beta-
MTCP1 mature T-cell proliferation 1
MYOT myotilin
MYOZ2 myozenin 2
NCAPD3 non-SMC condensin II complex, subunit D3
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFRKB nuclear factor related to kappaB binding protein
NHSL2 NHS-like 2
NLRX1 NLR family member X1
NRCAM neuronal cell adhesion molecule
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae)
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
NXPE1 neurexophilin and PC-esterase domain family, member 1
NXPE4 neurexophilin and PC-esterase domain family, member 4
OPCML opioid binding protein/cell adhesion molecule-like
OR13D1 olfactory receptor, family 13, subfamily D, member 1
OR2AE1 olfactory receptor, family 2, subfamily AE, member 1
OR2B2 olfactory receptor, family 2, subfamily B, member 2
OR2C3 olfactory receptor, family 2, subfamily C, member 3
OR4F21 olfactory receptor, family 4, subfamily F, member 21
OR4Q3 olfactory receptor, family 4, subfamily Q, member 3
OR4X2 olfactory receptor, family 4, subfamily X, member 2 (gene/pseudogene)
OR52A5 olfactory receptor, family 52, subfamily A, member 5
OR52L1 olfactory receptor, family 52, subfamily L, member 1
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1
OSM oncostatin M
OSR1 odd-skipped related transciption factor 1
OTUD1 OTU deubiquitinase 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PCA3 prostate cancer associated 3 (non-protein coding)
PCDH17 protocadherin 17
PCDHGA10 protocadherin gamma subfamily A, 10
PDE4DIP phosphodiesterase 4D interacting protein
PDE8B phosphodiesterase 8B
PDGFB platelet-derived growth factor beta polypeptide
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIGM phosphatidylinositol glycan anchor biosynthesis, class M
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLD6 phospholipase D family, member 6
PPAP2A phosphatidic acid phosphatase type 2A
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP5C protein phosphatase 5, catalytic subunit
PRAMEF2 PRAME family member 2
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRR16 proline rich 16
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PRUNE2 prune homolog 2 (Drosophila)
PTCH1 patched 1
RGCC regulator of cell cycle
RIC8B RIC8 guanine nucleotide exchange factor B
RIPPLY1 ripply transcriptional repressor 1
RNF214 ring finger protein 214
RNF26 ring finger protein 26
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPS25 ribosomal protein S25
RPUSD4 RNA pseudouridylate synthase domain containing 4
RUNX2 runt-related transcription factor 2
RYR3 ryanodine receptor 3
SAMHD1 SAM domain and HD domain 1
SBK2 SH3 domain binding kinase family, member 2
SELPLG selectin P ligand
SHCBP1L SHC SH2-domain binding protein 1-like
SIK3 SIK family kinase 3
SLC10A7 solute carrier family 10, member 7
SLC22A25 solute carrier family 22, member 25
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC35E2 solute carrier family 35, member E2
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC41A2 solute carrier family 41 (magnesium transporter), member 2
SLC44A4 solute carrier family 44, member 4
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SMCO3 single-pass membrane protein with coiled-coil domains 3
SNHG4 small nucleolar RNA host gene 4
SNX19 sorting nexin 19
SPACA3 sperm acrosome associated 3
SPDEF SAM pointed domain containing ETS transcription factor
SPNS3 spinster homolog 3 (Drosophila)
SPTA1 spectrin, alpha, erythrocytic 1
SPTSSB serine palmitoyltransferase, small subunit B
STAT5B signal transducer and activator of transcription 5B
STIM1 stromal interaction molecule 1
SYNPO2L synaptopodin 2-like
SYPL2 synaptophysin-like 2
TFEB transcription factor EB
THYN1 thymocyte nuclear protein 1
TIMP4 TIMP metallopeptidase inhibitor 4
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TMED4 transmembrane emp24 protein transport domain containing 4
TMEM136 transmembrane protein 136
TMEM218 transmembrane protein 218
TMEM25 transmembrane protein 25
TMOD1 tropomodulin 1
TNS2 tensin 2
TPM1 tropomyosin 1 (alpha)
TRAF1 TNF receptor-associated factor 1
TRAPPC4 trafficking protein particle complex 4
TSC22D2 TSC22 domain family, member 2
TSNAX-DISC1 TSNAX-DISC1 readthrough (NMD candidate)
TSPAN14 tetraspanin 14
TTLL8 tubulin tyrosine ligase-like family member 8
TXNRD1 thioredoxin reductase 1
UBD ubiquitin D
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE4A ubiquitination factor E4A
UMOD uromodulin
UPB1 ureidopropionase, beta
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
URGCP upregulator of cell proliferation
VCAN versican
VPREB1 pre-B lymphocyte 1
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
WBSCR27 Williams Beuren syndrome chromosome region 27
ZBED3 zinc finger, BED-type containing 3
ZBTB44 zinc finger and BTB domain containing 44
ZCCHC5 zinc finger, CCHC domain containing 5
ZNF267 zinc finger protein 267
ZNF747 zinc finger protein 747
ZNF804A zinc finger protein 804A
ZNF827 zinc finger protein 827
ZPBP2 zona pellucida binding protein 2
ZPR1 ZPR1 zinc finger

low expression

Symbol Name
APTX aprataxin
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
COPS7B COP9 signalosome subunit 7B
COPS8 COP9 signalosome subunit 8
CUL3 cullin 3
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EMC8 ER membrane protein complex subunit 8
FARSB phenylalanyl-tRNA synthetase, beta subunit
HDLBP high density lipoprotein binding protein
HINT3 histidine triad nucleotide binding protein 3
HSDL1 hydroxysteroid dehydrogenase like 1
MRPL44 mitochondrial ribosomal protein L44
MRS2 MRS2 magnesium transporter
NPR2 natriuretic peptide receptor 2
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
RAB5A RAB5A, member RAS oncogene family
STK25 serine/threonine kinase 25