Brain Lower Grade Glioma_LGG_TCGA-DU-5870-01A-11R-1708-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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356 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DU-5870-01A-11R-1708-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABHD2 abhydrolase domain containing 2
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACPP acid phosphatase, prostate
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSL6 acyl-CoA synthetase long-chain family member 6
ACSM1 acyl-CoA synthetase medium-chain family member 1
ACSM4 acyl-CoA synthetase medium-chain family member 4
ACTRT1 actin-related protein T1
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADGRG1 adhesion G protein-coupled receptor G1
ADGRV1 adhesion G protein-coupled receptor V1
ADRA1A adrenoceptor alpha 1A
AFAP1 actin filament associated protein 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGR2 anterior gradient 2
AHSG alpha-2-HS-glycoprotein
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALDOC aldolase C, fructose-bisphosphate
ALMS1P Alstrom syndrome 1 pseudogene
AMZ1 archaelysin family metallopeptidase 1
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APCDD1 adenomatosis polyposis coli down-regulated 1
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARPIN actin-related protein 2/3 complex inhibitor
ARRB1 arrestin, beta 1
ASCC3 activating signal cointegrator 1 complex subunit 3
ASTN1 astrotactin 1
ATM ATM serine/threonine kinase
ATP9A ATPase, class II, type 9A
BAALC brain and acute leukemia, cytoplasmic
BID BH3 interacting domain death agonist
C10ORF62 chromosome 10 open reading frame 62
C11ORF1 chromosome 11 open reading frame 1
C11ORF65 chromosome 11 open reading frame 65
C11ORF71 chromosome 11 open reading frame 71
C14ORF159 chromosome 14 open reading frame 159
C15ORF39 chromosome 15 open reading frame 39
C16ORF82 chromosome 16 open reading frame 82
C1ORF95 chromosome 1 open reading frame 95
C2CD3 C2 calcium-dependent domain containing 3
C2ORF72 chromosome 2 open reading frame 72
C3ORF70 chromosome 3 open reading frame 70
C9ORF129 chromosome 9 open reading frame 129
CALN1 calneuron 1
CASKIN2 CASK interacting protein 2
CATSPER2P1 cation channel, sperm associated 2 pseudogene 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC171 coiled-coil domain containing 171
CCDC85C coiled-coil domain containing 85C
CCSER1 coiled-coil serine-rich protein 1
CD300LG CD300 molecule-like family member g
CD38 CD38 molecule
CDC14C cell division cycle 14C
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLCN2 chloride channel, voltage-sensitive 2
CLDN8 claudin 8
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CMTM4 CKLF-like MARVEL transmembrane domain containing 4
COG2 component of oligomeric golgi complex 2
COL18A1-AS1 COL18A1 antisense RNA 1
CPT1A carnitine palmitoyltransferase 1A (liver)
CRISP3 cysteine-rich secretory protein 3
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSNK1G2-AS1 CSNK1G2 antisense RNA 1
CT45A4 cancer/testis antigen family 45, member A4
CTBP1-AS2 CTBP1 antisense RNA 2 (head to head)
CTSO cathepsin O
CYB5D2 cytochrome b5 domain containing 2
DAB2IP DAB2 interacting protein
DAGLA diacylglycerol lipase, alpha
DAO D-amino-acid oxidase
DGKD diacylglycerol kinase, delta 130kDa
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DIRC2 disrupted in renal carcinoma 2
DISC1 disrupted in schizophrenia 1
DKFZP779M0652 uncharacterized DKFZp779M0652
DLAT dihydrolipoamide S-acetyltransferase
DNMBP-AS1 DNMBP antisense RNA 1
DPP8 dipeptidyl-peptidase 8
DPY19L3 dpy-19-like 3 (C. elegans)
DSCR3 Down syndrome critical region 3
EDA2R ectodysplasin A2 receptor
ENDOU endonuclease, polyU-specific
EPAS1 endothelial PAS domain protein 1
F5 coagulation factor V (proaccelerin, labile factor)
FADS2 fatty acid desaturase 2
FAM118B family with sequence similarity 118, member B
FAM167A family with sequence similarity 167, member A
FAM168A family with sequence similarity 168, member A
FAM196B family with sequence similarity 196, member B
FAM218A family with sequence similarity 218, member A
FAM26D family with sequence similarity 26, member D
FAM66C family with sequence similarity 66, member C
FAM90A7P putative protein FAM90A7
FAM92A1P2 family with sequence similarity 92, member A3
FAT1 FAT atypical cadherin 1
FCHSD2 FCH and double SH3 domains 2
FDXACB1 ferredoxin-fold anticodon binding domain containing 1
FGD3 FYVE, RhoGEF and PH domain containing 3
FICD FIC domain containing
FIGLA folliculogenesis specific basic helix-loop-helix
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FRK fyn-related Src family tyrosine kinase
FRMPD1 FERM and PDZ domain containing 1
FZD4 frizzled class receptor 4
G6PC glucose-6-phosphatase, catalytic subunit
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16
GAN gigaxonin
GATSL3 GATS protein-like 3
GGTA1P glycoprotein, alpha-galactosyltransferase 1 pseudogene
GLYATL1 glycine-N-acyltransferase-like 1
GLYATL2 glycine-N-acyltransferase-like 2
GMCL1P1 germ cell-less, spermatogenesis associated 1 pseudogene 1
GP2 glycoprotein 2 (zymogen granule membrane)
GPR161 G protein-coupled receptor 161
GPR27 G protein-coupled receptor 27
GPR75 G protein-coupled receptor 75
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRID2 glutamate receptor, ionotropic, delta 2
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRM5 glutamate receptor, metabotropic 5
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HACD3 3-hydroxyacyl-CoA dehydratase 3
HCG4B HLA complex group 4B (non-protein coding)
HKDC1 hexokinase domain containing 1
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
HSFY1P1 heat shock transcription factor, Y-linked 1 pseudogene 1
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFFO2 intermediate filament family orphan 2
IGSF9B immunoglobulin superfamily, member 9B
IL20 interleukin 20
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ITPK1-AS1 ITPK1 antisense RNA 1
JPH2 junctophilin 2
KCNG4 potassium channel, voltage gated modifier subfamily G, member 4
KCNIP2 Kv channel interacting protein 2
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCTD21 potassium channel tetramerization domain containing 21
KIAA1161 KIAA1161
KIF21B kinesin family member 21B
KIF6 kinesin family member 6
KLHL25 kelch-like family member 25
KLK2 kallikrein-related peptidase 2
KLK3 kallikrein-related peptidase 3
KLK4 kallikrein-related peptidase 4
KRT12 keratin 12, type I
LHFPL1 lipoma HMGIC fusion partner-like 1
LHX3 LIM homeobox 3
LINC00052 long intergenic non-protein coding RNA 52
LINC00472 long intergenic non-protein coding RNA 472
LINC00652 long intergenic non-protein coding RNA 652
LOC100128239 uncharacterized LOC100128239
LOC283922 pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
LOC285692 uncharacterized LOC285692
LOC441454 prothymosin, alpha pseudogene
LOC643923 uncharacterized LOC643923
LOC650293 seven transmembrane helix receptor
LOC652276 potassium channel tetramerization domain containing 5 pseudogene
LPL lipoprotein lipase
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MCCD1 mitochondrial coiled-coil domain 1
MCF2 MCF.2 cell line derived transforming sequence
MCUR1 mitochondrial calcium uniporter regulator 1
MFGE8 milk fat globule-EGF factor 8 protein
MFSD11 major facilitator superfamily domain containing 11
MIEF1 mitochondrial elongation factor 1
MMD2 monocyte to macrophage differentiation-associated 2
MON1B MON1 secretory trafficking family member B
MPV17L MPV17 mitochondrial membrane protein-like
MRVI1 murine retrovirus integration site 1 homolog
MSMB microseminoprotein, beta-
MSX2 msh homeobox 2
MTM1 myotubularin 1
MUT methylmalonyl CoA mutase
MYH15 myosin, heavy chain 15
MYO10 myosin X
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAP1L6 nucleosome assembly protein 1-like 6
NAT8 N-acetyltransferase 8 (GCN5-related, putative)
NAV1 neuron navigator 1
NCAM1 neural cell adhesion molecule 1
NCAN neurocan
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NHSL1 NHS-like 1
NNT nicotinamide nucleotide transhydrogenase
NPAT nuclear protein, ataxia-telangiectasia locus
NRG1 neuregulin 1
NRP2 neuropilin 2
NT5C1A 5'-nucleotidase, cytosolic IA
NTM neurotrimin
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NXPE2 neurexophilin and PC-esterase domain family, member 2
OR14A16 olfactory receptor, family 14, subfamily A, member 16
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4
OR2L1P olfactory receptor, family 2, subfamily L, member 1 pseudogene
OR2M1P olfactory receptor, family 2, subfamily M, member 1 pseudogene
OR2M4 olfactory receptor, family 2, subfamily M, member 4
OR2T6 olfactory receptor, family 2, subfamily T, member 6
OR51B5 olfactory receptor, family 51, subfamily B, member 5
OR52D1 olfactory receptor, family 52, subfamily D, member 1
OR52H1 olfactory receptor, family 52, subfamily H, member 1
OR52N2 olfactory receptor, family 52, subfamily N, member 2
OR56B4 olfactory receptor, family 56, subfamily B, member 4
OR6T1 olfactory receptor, family 6, subfamily T, member 1
OSBPL11 oxysterol binding protein-like 11
PANX1 pannexin 1
PARP8 poly (ADP-ribose) polymerase family, member 8
PAX8 paired box 8
PBLD phenazine biosynthesis-like protein domain containing
PCA3 prostate cancer associated 3 (non-protein coding)
PCDHA1 protocadherin alpha 1
PCDHAC1 protocadherin alpha subfamily C, 1
PCDHGA6 protocadherin gamma subfamily A, 6
PCDHGC3 protocadherin gamma subfamily C, 3
PCDHGC4 protocadherin gamma subfamily C, 4
PCSK6 proprotein convertase subtilisin/kexin type 6
PDC phosducin
PDZD2 PDZ domain containing 2
PDZD8 PDZ domain containing 8
PEA15 phosphoprotein enriched in astrocytes 15
PEAK1 pseudopodium-enriched atypical kinase 1
PIGR polymeric immunoglobulin receptor
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PIKFYVE phosphoinositide kinase, FYVE finger containing
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLET1 placenta expressed transcript 1
PLXNA4 plexin A4
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRELP proline/arginine-rich end leucine-rich repeat protein
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PRR23A proline rich 23A
PRR5-ARHGAP8 PRR5-ARHGAP8 readthrough
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPRA protein tyrosine phosphatase, receptor type, A
PWAR5 Prader Willi/Angelman region RNA 5
PYGB phosphorylase, glycogen; brain
R3HDML R3H domain containing-like
RAB31 RAB31, member RAS oncogene family
RASA3 RAS p21 protein activator 3
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
REG4 regenerating islet-derived family, member 4
RFPL1 ret finger protein-like 1
RHBDL3 rhomboid, veinlet-like 3 (Drosophila)
RNF113B ring finger protein 113B
RNF121 ring finger protein 121
RNF215 ring finger protein 215
ROPN1 rhophilin associated tail protein 1
RSF1 remodeling and spacing factor 1
RSPH6A radial spoke head 6 homolog A (Chlamydomonas)
SASH1 SAM and SH3 domain containing 1
SCD5 stearoyl-CoA desaturase 5
SCGB1C1 secretoglobin, family 1C, member 1
SCN3B sodium channel, voltage gated, type III beta subunit
SCTR secretin receptor
SEC63 SEC63 homolog (S. cerevisiae)
SELL selectin L
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
SETD7 SET domain containing (lysine methyltransferase) 7
SF3A1 splicing factor 3a, subunit 1, 120kDa
SFXN5 sideroflexin 5
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SHISA6 shisa family member 6
SHISA9 shisa family member 9
SIDT2 SID1 transmembrane family, member 2
SLC18B1 solute carrier family 18, subfamily B, member 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC35G6 solute carrier family 35, member G6
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2
SLC38A1 solute carrier family 38, member 1
SLC39A9 solute carrier family 39, member 9
SLC44A4 solute carrier family 44, member 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLIT1 slit homolog 1 (Drosophila)
SNORA2A small nucleolar RNA, H/ACA box 2A
SNX19 sorting nexin 19
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPO11 SPO11 meiotic protein covalently bound to DSB
SPRY3 sprouty homolog 3 (Drosophila)
SRSF8 serine/arginine-rich splicing factor 8
SSTR2 somatostatin receptor 2
SULF2 sulfatase 2
SUPT20HL2 suppressor of Ty 20 homolog (S. cerevisiae)-like 2
SUSD5 sushi domain containing 5
SYT11 synaptotagmin XI
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TAS2R3 taste receptor, type 2, member 3
TAS2R7 taste receptor, type 2, member 7
TBC1D10A TBC1 domain family, member 10A
TBC1D5 TBC1 domain family, member 5
TBCEL tubulin folding cofactor E-like
TBX10 T-box 10
TECTA tectorin alpha
TET3 tet methylcytosine dioxygenase 3
TGM4 transglutaminase 4
THSD4 thrombospondin, type I, domain containing 4
TIGIT T cell immunoreceptor with Ig and ITIM domains
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLX1NB TLX1 neighbor
TM4SF19 transmembrane 4 L six family member 19
TMEM135 transmembrane protein 135
TMEM200C transmembrane protein 200C
TMEM8B transmembrane protein 8B
TMEM95 transmembrane protein 95
TMPRSS11F transmembrane protease, serine 11F
TRAK1 trafficking protein, kinesin binding 1
TRIM14 tripartite motif containing 14
TRIM67 tripartite motif containing 67
TRIM9 tripartite motif containing 9
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TSPAN1 tetraspanin 1
TTC39B tetratricopeptide repeat domain 39B
TUB tubby bipartite transcription factor
TUBB1 tubulin, beta 1 class VI
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
VEPH1 ventricular zone expressed PH domain-containing 1
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
VWA5A von Willebrand factor A domain containing 5A
WDFY3-AS2 WDFY3 antisense RNA 2
WDR88 WD repeat domain 88
WWC1 WW and C2 domain containing 1
XKR3 XK, Kell blood group complex subunit-related family, member 3
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZC3H12C zinc finger CCCH-type containing 12C
ZMAT3 zinc finger, matrin-type 3
ZNF597 zinc finger protein 597
ZNF648 zinc finger protein 648
ZNF676 zinc finger protein 676
ZNF705D zinc finger protein 705D
ZNF710 zinc finger protein 710
ZNF843 zinc finger protein 843

low expression

Symbol Name
C18ORF21 chromosome 18 open reading frame 21
IER3IP1 immediate early response 3 interacting protein 1
MAST2 microtubule associated serine/threonine kinase 2
MBD1 methyl-CpG binding domain protein 1
PYGO2 pygopus family PHD finger 2
SMAD2 SMAD family member 2
TMX3 thioredoxin-related transmembrane protein 3