Brain Lower Grade Glioma_LGG_TCGA-DU-6542-01A-11R-1896-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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333 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DU-6542-01A-11R-1896-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
AFAP1L2 actin filament associated protein 1-like 2
AGO3 argonaute RISC catalytic component 3
AMOTL2 angiomotin like 2
ANAPC7 anaphase promoting complex subunit 7
ANKRD13A ankyrin repeat domain 13A
ANKRD17 ankyrin repeat domain 17
APP amyloid beta (A4) precursor protein
AQP7P1 aquaporin 7 pseudogene 1
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL14 ADP-ribosylation factor-like 14
ASGR2 asialoglycoprotein receptor 2
ASXL3 additional sex combs like transcriptional regulator 3
ATF6B activating transcription factor 6 beta
ATF7IP activating transcription factor 7 interacting protein
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATXN2 ataxin 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C12ORF76 chromosome 12 open reading frame 76
C12ORF77 chromosome 12 open reading frame 77
C17ORF47 chromosome 17 open reading frame 47
C1ORF110 chromosome 1 open reading frame 110
C1QTNF9 C1q and tumor necrosis factor related protein 9
C6ORF10 chromosome 6 open reading frame 10
C8A complement component 8, alpha polypeptide
CABIN1 calcineurin binding protein 1
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CCBL2 cysteine conjugate-beta lyase 2
CCDC144B coiled-coil domain containing 144B (pseudogene)
CDH18 cadherin 18, type 2
CDK8 cyclin-dependent kinase 8
CDV3 CDV3 homolog (mouse)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CELF1 CUGBP, Elav-like family member 1
CHD8 chromodomain helicase DNA binding protein 8
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLCA1 chloride channel accessory 1
CLDN25 claudin 25
COL4A6 collagen, type IV, alpha 6
COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
CORO1C coronin, actin binding protein, 1C
CPNE3 copine III
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CRLF2 cytokine receptor-like factor 2
CTNND1 catenin (cadherin-associated protein), delta 1
CYB5RL cytochrome b5 reductase-like
DCAF16 DDB1 and CUL4 associated factor 16
DDB1 damage-specific DNA binding protein 1, 127kDa
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DEFB119 defensin, beta 119
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37
DIAPH2 diaphanous-related formin 2
DIXDC1 DIX domain containing 1
DUSP19 dual specificity phosphatase 19
DUSP21 dual specificity phosphatase 21
E2F3 E2F transcription factor 3
ERCC6L2 excision repair cross-complementation group 6-like 2
F13B coagulation factor XIII, B polypeptide
FAM120A family with sequence similarity 120A
FAM131C family with sequence similarity 131, member C
FAM13C family with sequence similarity 13, member C
FAM205BP transmembrane protein C9orf144B pseudogene
FAM222A family with sequence similarity 222, member A
FBLN5 fibulin 5
FBXO21 F-box protein 21
FBXW8 F-box and WD repeat domain containing 8
FGF12 fibroblast growth factor 12
FGF23 fibroblast growth factor 23
FOXJ3 forkhead box J3
FOXP2 forkhead box P2
FRG2B FSHD region gene 2 family, member B
FRG2C FSHD region gene 2 family, member C
FRMD5 FERM domain containing 5
GAB1 GRB2-associated binding protein 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GANC glucosidase, alpha; neutral C
GAREM GRB2 associated, regulator of MAPK1
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GDF2 growth differentiation factor 2
GEMIN5 gem (nuclear organelle) associated protein 5
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GJA10 gap junction protein, alpha 10, 62kDa
GLP1R glucagon-like peptide 1 receptor
GMPR2 guanosine monophosphate reductase 2
GUSBP2 glucuronidase, beta pseudogene 2
HCG18 HLA complex group 18 (non-protein coding)
HEATR1 HEAT repeat containing 1
HELZ helicase with zinc finger
HIST1H1T histone cluster 1, H1t
HIST1H2AK histone cluster 1, H2ak
HIST2H2BA histone cluster 2, H2ba (pseudogene)
HIST3H2BB histone cluster 3, H2bb
HIST4H4 histone cluster 4, H4
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HM13 histocompatibility (minor) 13
HMG20A high mobility group 20A
HR hair growth associated
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
ICK intestinal cell (MAK-like) kinase
IFNA1 interferon, alpha 1
IGSF9B immunoglobulin superfamily, member 9B
IL17RA interleukin 17 receptor A
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IPO4 importin 4
ITGB6 integrin, beta 6
KCNK6 potassium channel, two pore domain subfamily K, member 6
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA0100 KIAA0100
KIAA1462 KIAA1462
KIF21B kinesin family member 21B
KLHL40 kelch-like family member 40
KLHL41 kelch-like family member 41
KLK9 kallikrein-related peptidase 9
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT25 keratin 25, type I
KRTAP1-1 keratin associated protein 1-1
KRTAP10-12 keratin associated protein 10-12
KRTAP4-7 keratin associated protein 4-7
LCE1A late cornified envelope 1A
LCE6A late cornified envelope 6A
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2
LINC00028 long intergenic non-protein coding RNA 28
LINC00051 long intergenic non-protein coding RNA 51
LINC00476 long intergenic non-protein coding RNA 476
LMOD3 leiomodin 3 (fetal)
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
MAGEA8 melanoma antigen family A8
MAGEB16 melanoma antigen family B16
MAML2 mastermind-like 2 (Drosophila)
MAN1A2 mannosidase, alpha, class 1A, member 2
MAP2K6 mitogen-activated protein kinase kinase 6
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MCPH1 microcephalin 1
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
MED13L mediator complex subunit 13-like
MED28 mediator complex subunit 28
METTL13 methyltransferase like 13
MGC2889 uncharacterized protein MGC2889
MIA2 melanoma inhibitory activity 2
MIER1 mesoderm induction early response 1, transcriptional regulator
MLEC malectin
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPHOSPH8 M-phase phosphoprotein 8
MPHOSPH9 M-phase phosphoprotein 9
MRPS27 mitochondrial ribosomal protein S27
NCKAP5 NCK-associated protein 5
NCOR2 nuclear receptor corepressor 2
NCR2 natural cytotoxicity triggering receptor 2
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
NOBOX NOBOX oogenesis homeobox
NOMO1 NODAL modulator 1
NOMO2 NODAL modulator 2
NOTO notochord homeobox
NRAP nebulin-related anchoring protein
NSUN4 NOP2/Sun domain family, member 4
NXPE3 neurexophilin and PC-esterase domain family, member 3
NXPE4 neurexophilin and PC-esterase domain family, member 4
OLFML2B olfactomedin-like 2B
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
OR14C36 olfactory receptor, family 14, subfamily C, member 36
OR1A1 olfactory receptor, family 1, subfamily A, member 1
OR1J4 olfactory receptor, family 1, subfamily J, member 4
OR1K1 olfactory receptor, family 1, subfamily K, member 1
OR2C3 olfactory receptor, family 2, subfamily C, member 3
OR2D2 olfactory receptor, family 2, subfamily D, member 2
OR2T1 olfactory receptor, family 2, subfamily T, member 1
OR2W5 olfactory receptor, family 2, subfamily W, member 5 (gene/pseudogene)
OR3A4P olfactory receptor, family 3, subfamily A, member 4 pseudogene
OR4B1 olfactory receptor, family 4, subfamily B, member 1
OR4D10 olfactory receptor, family 4, subfamily D, member 10
OR4D9 olfactory receptor, family 4, subfamily D, member 9
OR52B6 olfactory receptor, family 52, subfamily B, member 6
OR52M1 olfactory receptor, family 52, subfamily M, member 1
OR5B12 olfactory receptor, family 5, subfamily B, member 12
OR5B3 olfactory receptor, family 5, subfamily B, member 3
OR6B1 olfactory receptor, family 6, subfamily B, member 1
OR6C75 olfactory receptor, family 6, subfamily C, member 75
OR6F1 olfactory receptor, family 6, subfamily F, member 1
OR7A10 olfactory receptor, family 7, subfamily A, member 10
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PABPC1P2 poly(A) binding protein, cytoplasmic 1 pseudogene 2
PADI6 peptidyl arginine deiminase, type VI
PAGE1 P antigen family, member 1 (prostate associated)
PARP8 poly (ADP-ribose) polymerase family, member 8
PCDH17 protocadherin 17
PCDHB18P protocadherin beta 18 pseudogene
PCDHGB4 protocadherin gamma subfamily B, 4
PDCD11 programmed cell death 11
PDGFC platelet derived growth factor C
PDZRN3 PDZ domain containing ring finger 3
PEAK1 pseudopodium-enriched atypical kinase 1
PHF20 PHD finger protein 20
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PLA2G4E phospholipase A2, group IVE
POGLUT1 protein O-glucosyltransferase 1
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPT1 palmitoyl-protein thioesterase 1
PPT2 palmitoyl-protein thioesterase 2
PRDM4 PR domain containing 4
PROS1 protein S (alpha)
PRR21 proline rich 21
PRR27 proline rich 27
PRR30 proline rich 30
PRRC2A proline-rich coiled-coil 2A
PRRX1 paired related homeobox 1
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PWP1 PWP1 homolog (S. cerevisiae)
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RBM19 RNA binding motif protein 19
RBP3 retinol binding protein 3, interstitial
RCC2 regulator of chromosome condensation 2
REG4 regenerating islet-derived family, member 4
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS1 regulator of G-protein signaling 1
RIC8B RIC8 guanine nucleotide exchange factor B
RNF10 ring finger protein 10
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RPA4 replication protein A4, 30kDa
RPAP2 RNA polymerase II associated protein 2
RPL7L1 ribosomal protein L7-like 1
RSC1A1 regulatory solute carrier protein, family 1, member 1
RSPRY1 ring finger and SPRY domain containing 1
RTP2 receptor (chemosensory) transporter protein 2
RTTN rotatin
SART3 squamous cell carcinoma antigen recognized by T cells 3
SBNO1 strawberry notch homolog 1 (Drosophila)
SCN3A sodium channel, voltage gated, type III alpha subunit
SCYL2 SCY1-like 2 (S. cerevisiae)
SERINC5 serine incorporator 5
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
SH3BP1 SH3-domain binding protein 1
SH3D19 SH3 domain containing 19
SH3RF1 SH3 domain containing ring finger 1
SIRT2 sirtuin 2
SIRT4 sirtuin 4
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLITRK6 SLIT and NTRK-like family, member 6
SMAD3 SMAD family member 3
SNHG4 small nucleolar RNA host gene 4
SNORD116-20 small nucleolar RNA, C/D box 116-20
SOGA1 suppressor of glucose, autophagy associated 1
SPDYE6 speedy/RINGO cell cycle regulator family member E6
SPPL3 signal peptide peptidase like 3
SPTSSB serine palmitoyltransferase, small subunit B
STK4 serine/threonine kinase 4
STON1-GTF2A1L STON1-GTF2A1L readthrough
STPG2 sperm-tail PG-rich repeat containing 2
STRADB STE20-related kinase adaptor beta
SZT2 seizure threshold 2 homolog (mouse)
TAC1 tachykinin, precursor 1
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAS2R9 taste receptor, type 2, member 9
TCF12 transcription factor 12
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TGM6 transglutaminase 6
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM4SF4 transmembrane 4 L six family member 4
TMEM241 transmembrane protein 241
TMEM263 transmembrane protein 263
TMEM57 transmembrane protein 57
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOR1AIP2 torsin A interacting protein 2
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM58 tripartite motif containing 58
TRUB2 TruB pseudouridine (psi) synthase family member 2
TYW5 tRNA-yW synthesizing protein 5
UBE4B ubiquitination factor E4B
UBFD1 ubiquitin family domain containing 1
UNC119B unc-119 homolog B (C. elegans)
USP24 ubiquitin specific peptidase 24
USP30 ubiquitin specific peptidase 30
USP35 ubiquitin specific peptidase 35
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
UTS2B urotensin 2B
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WIF1 WNT inhibitory factor 1
ZAN zonadhesin (gene/pseudogene)
ZBTB20 zinc finger and BTB domain containing 20
ZFP91 ZFP91 zinc finger protein
ZNF318 zinc finger protein 318
ZNF426 zinc finger protein 426
ZNF469 zinc finger protein 469
ZNF488 zinc finger protein 488
ZNF560 zinc finger protein 560
ZNF568 zinc finger protein 568
ZNF570 zinc finger protein 570
ZNF573 zinc finger protein 573
ZNF585A zinc finger protein 585A
ZNF605 zinc finger protein 605
ZNF804A zinc finger protein 804A
ZNF827 zinc finger protein 827
ZNF829 zinc finger protein 829
ZNF883 zinc finger protein 883
ZSCAN12 zinc finger and SCAN domain containing 12
ZSCAN12P1 zinc finger and SCAN domain containing 12 pseudogene 1
ZSCAN20 zinc finger and SCAN domain containing 20

low expression

Symbol Name
AKIRIN2 akirin 2
ATG5 autophagy related 5
CCNC cyclin C
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
ECHDC1 ethylmalonyl-CoA decarboxylase 1
FAM229B family with sequence similarity 229, member B
HINT3 histidine triad nucleotide binding protein 3
HMGN3 high mobility group nucleosomal binding domain 3
MRPL18 mitochondrial ribosomal protein L18
ORC3 origin recognition complex, subunit 3
RAP2C RAP2C, member of RAS oncogene family
REPS1 RALBP1 associated Eps domain containing 1
RNF146 ring finger protein 146
SCCPDH saccharopine dehydrogenase (putative)
SNX3 sorting nexin 3
TBP TATA box binding protein
TCP1 t-complex 1
ZUFSP zinc finger with UFM1-specific peptidase domain