Brain Lower Grade Glioma_LGG_TCGA-DU-7299-01A-21R-2027-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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255 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DU-7299-01A-21R-2027-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABI1 abl-interactor 1
ACE2 angiotensin I converting enzyme 2
ACOT9 acyl-CoA thioesterase 9
ACY3 aminoacylase 3
AGO4 argonaute RISC catalytic component 4
AKAP3 A kinase (PRKA) anchor protein 3
ANKK1 ankyrin repeat and kinase domain containing 1
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ANXA13 annexin A13
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APAF1 apoptotic peptidase activating factor 1
APOO apolipoprotein O
ARHGAP12 Rho GTPase activating protein 12
ARHGAP21 Rho GTPase activating protein 21
ARHGAP42 Rho GTPase activating protein 42
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ATF7IP activating transcription factor 7 interacting protein
ATMIN ATM interactor
ATN1 atrophin 1
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
BAAT bile acid CoA:amino acid N-acyltransferase
BMI1 BMI1 proto-oncogene, polycomb ring finger
C10ORF111 chromosome 10 open reading frame 111
C10ORF12 chromosome 10 open reading frame 12
C12ORF4 chromosome 12 open reading frame 4
C2CD5 C2 calcium-dependent domain containing 5
C3ORF70 chromosome 3 open reading frame 70
CAMK1G calcium/calmodulin-dependent protein kinase IG
CCDC144B coiled-coil domain containing 144B (pseudogene)
CCDC172 coiled-coil domain containing 172
CCDC7 coiled-coil domain containing 7
CCDC88A coiled-coil domain containing 88A
CCDC91 coiled-coil domain containing 91
CD9 CD9 molecule
CDK19 cyclin-dependent kinase 19
CEPT1 choline/ethanolamine phosphotransferase 1
CHD4 chromodomain helicase DNA binding protein 4
CHIA chitinase, acidic
CLEC1B C-type lectin domain family 1, member B
CNTN6 contactin 6
COL9A1 collagen, type IX, alpha 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COPS7A COP9 signalosome subunit 7A
CUL2 cullin 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DEFA4 defensin, alpha 4, corticostatin
DENND5B DENN/MADD domain containing 5B
DGKH diacylglycerol kinase, eta
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DNM1L dynamin 1-like
DPP10 dipeptidyl-peptidase 10 (non-functional)
DRD2 dopamine receptor D2
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
EAF2 ELL associated factor 2
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELAVL4 ELAV like neuron-specific RNA binding protein 4
EP300 E1A binding protein p300
EPC1 enhancer of polycomb homolog 1 (Drosophila)
ERGIC2 ERGIC and golgi 2
ETNK1 ethanolamine kinase 1
EYS eyes shut homolog (Drosophila)
F8 coagulation factor VIII, procoagulant component
F9 coagulation factor IX
FAM63B family with sequence similarity 63, member B
FETUB fetuin B
FKBP4 FK506 binding protein 4, 59kDa
FMO2 flavin containing monooxygenase 2 (non-functional)
FOLH1B folate hydrolase 1B
FOXE1 forkhead box E1
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GJA3 gap junction protein, alpha 3, 46kDa
GLUL glutamate-ammonia ligase
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GOLGA8F golgin A8 family, member F
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR45 G protein-coupled receptor 45
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GRM5 glutamate receptor, metabotropic 5
GSTA2 glutathione S-transferase alpha 2
HIST3H2BB histone cluster 3, H2bb
ING4 inhibitor of growth family, member 4
IPO8 importin 8
ITFG2 integrin alpha FG-GAP repeat containing 2
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNIP1 Kv channel interacting protein 1
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNK6 potassium channel, two pore domain subfamily K, member 6
KIAA0754 KIAA0754
KIAA1551 KIAA1551
KIAA1715 KIAA1715
KIAA2018 KIAA2018
KIF5B kinesin family member 5B
KIR3DP1 killer cell immunoglobulin-like receptor, three domains, pseudogene 1
KLF12 Kruppel-like factor 12
KLHL23 kelch-like family member 23
KLHL42 kelch-like family member 42
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KRAS Kirsten rat sarcoma viral oncogene homolog
KRTAP3-3 keratin associated protein 3-3
LDHB lactate dehydrogenase B
LINC00115 long intergenic non-protein coding RNA 115
LINC00574 long intergenic non-protein coding RNA 574
LINC01548 long intergenic non-protein coding RNA 1548
LOC392196 ubiquitin specific peptidase 17-like family member 2 pseudogene
LRRC37B leucine rich repeat containing 37B
LRRK2 leucine-rich repeat kinase 2
LYRM5 LYR motif containing 5
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK8 mitogen-activated protein kinase 8
MAST2 microtubule associated serine/threonine kinase 2
METTL20 methyltransferase like 20
MLF2 myeloid leukemia factor 2
MORC1 MORC family CW-type zinc finger 1
MRPS35 mitochondrial ribosomal protein S35
MSL3 male-specific lethal 3 homolog (Drosophila)
MT4 metallothionein 4
MTMR10 myotubularin related protein 10
MYO9A myosin IXA
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NALCN sodium leak channel, non selective
NKAIN1 Na+/K+ transporting ATPase interacting 1
NLGN4Y neuroligin 4, Y-linked
NMUR2 neuromedin U receptor 2
NPPA natriuretic peptide A
NRIP2 nuclear receptor interacting protein 2
NRTN neurturin
NTSR1 neurotensin receptor 1 (high affinity)
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10
NXPH1 neurexophilin 1
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OLAH oleoyl-ACP hydrolase
OR1J4 olfactory receptor, family 1, subfamily J, member 4
OR2A14 olfactory receptor, family 2, subfamily A, member 14
OR2A5 olfactory receptor, family 2, subfamily A, member 5
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2
OR2V2 olfactory receptor, family 2, subfamily V, member 2
OR4K5 olfactory receptor, family 4, subfamily K, member 5
PAX1 paired box 1
PCDH20 protocadherin 20
PCDHA11 protocadherin alpha 11
PCDHB16 protocadherin beta 16
PCDHB8 protocadherin beta 8
PCDHGA1 protocadherin gamma subfamily A, 1
PDZRN4 PDZ domain containing ring finger 4
PEG3 paternally expressed 3
PEX5 peroxisomal biogenesis factor 5
PIANP PILR alpha associated neural protein
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G4E phospholipase A2, group IVE
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1
QDPR quinoid dihydropteridine reductase
RAB8B RAB8B, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RBM4B RNA binding motif protein 4B
REPS2 RALBP1 associated Eps domain containing 2
RGAG1 retrotransposon gag domain containing 1
RICTOR RPTOR independent companion of MTOR, complex 2
RNF121 ring finger protein 121
RNF144A ring finger protein 144A
RNF5P1 ring finger protein 5, E3 ubiquitin protein ligase pseudogene 1
SATB1 SATB homeobox 1
SCGB1C1 secretoglobin, family 1C, member 1
SCRT2 scratch family zinc finger 2
SFMBT2 Scm-like with four mbt domains 2
SHISA7 shisa family member 7
SHROOM2 shroom family member 2
SIX1 SIX homeobox 1
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SNRK SNF related kinase
SOX5 SRY (sex determining region Y)-box 5
SPANXC SPANX family, member C
SSTR1 somatostatin receptor 1
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
ST7L suppression of tumorigenicity 7 like
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAG1 stromal antigen 1
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STRAP serine/threonine kinase receptor associated protein
SYN3 synapsin III
SYNE3 spectrin repeat containing, nuclear envelope family member 3
TACC2 transforming, acidic coiled-coil containing protein 2
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TAS2R46 taste receptor, type 2, member 46
TBX15 T-box 15
TCEANC transcription elongation factor A (SII) N-terminal and central domain containing
TECRL trans-2,3-enoyl-CoA reductase-like
TERF2 telomeric repeat binding factor 2
TEX13B testis expressed 13B
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THAP1 THAP domain containing, apoptosis associated protein 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIAM2 T-cell lymphoma invasion and metastasis 2
TIMP4 TIMP metallopeptidase inhibitor 4
TM7SF3 transmembrane 7 superfamily member 3
TMEM27 transmembrane protein 27
TPH1 tryptophan hydroxylase 1
TPI1 triosephosphate isomerase 1
TRAPPC2 trafficking protein particle complex 2
TRIB2 tribbles pseudokinase 2
TRIM62 tripartite motif containing 62
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase
TSPY1 testis specific protein, Y-linked 1
TUBB1 tubulin, beta 1 class VI
TULP3 tubby like protein 3
TXLNG taxilin gamma
UBE4B ubiquitination factor E4B
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
USP24 ubiquitin specific peptidase 24
USP43 ubiquitin specific peptidase 43
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WAC WW domain containing adaptor with coiled-coil
WDR77 WD repeat domain 77
ZBED1 zinc finger, BED-type containing 1
ZEB1 zinc finger E-box binding homeobox 1
ZIM2 zinc finger, imprinted 2
ZNF114 zinc finger protein 114
ZNF233 zinc finger protein 233
ZNF384 zinc finger protein 384
ZNF583 zinc finger protein 583
ZNF697 zinc finger protein 697

low expression

Symbol Name
C15ORF40 chromosome 15 open reading frame 40
COX18 COX18 cytochrome c oxidase assembly factor
EIF4E eukaryotic translation initiation factor 4E
FAM103A1 family with sequence similarity 103, member A1
FAM219B family with sequence similarity 219, member B
FBXO22 F-box protein 22
HELQ helicase, POLQ-like
MESDC2 mesoderm development candidate 2
MORF4L1 mortality factor 4 like 1
MRS2 MRS2 magnesium transporter
PEBP1 phosphatidylethanolamine binding protein 1
PLA2G12A phospholipase A2, group XIIA
RCN2 reticulocalbin 2, EF-hand calcium binding domain
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
TMEM177 transmembrane protein 177
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
WDR61 WD repeat domain 61
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules