Brain Lower Grade Glioma_LGG_TCGA-DU-A6S7-01A-21R-A32Q-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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296 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-DU-A6S7-01A-21R-A32Q-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACRBP acrosin binding protein
ADCY7 adenylate cyclase 7
AGAP7P ArfGAP with GTPase domain, ankyrin repeat and PH domain 7, pseudogene
AKAP13 A kinase (PRKA) anchor protein 13
ALOX12 arachidonate 12-lipoxygenase
ANKRD11 ankyrin repeat domain 11
ANKRD13B ankyrin repeat domain 13B
ANKRD20A3 ankyrin repeat domain 20 family, member A3
ANKRD20A8P ankyrin repeat domain 20 family, member A8, pseudogene
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARID1A AT rich interactive domain 1A (SWI-like)
ARRB2 arrestin, beta 2
ASCL3 achaete-scute family bHLH transcription factor 3
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
ATXN7L2 ataxin 7-like 2
BCAN brevican
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
C17ORF78 chromosome 17 open reading frame 78
C17ORF85 chromosome 17 open reading frame 85
C19ORF38 chromosome 19 open reading frame 38
C3ORF30 chromosome 3 open reading frame 30
C8ORF31 chromosome 8 open reading frame 31
C9ORF106 chromosome 9 open reading frame 106
C9ORF152 chromosome 9 open reading frame 152
CACNG7 calcium channel, voltage-dependent, gamma subunit 7
CARD14 caspase recruitment domain family, member 14
CARD18 caspase recruitment domain family, member 18
CATSPERG catsper channel auxiliary subunit gamma
CCAR2 cell cycle and apoptosis regulator 2
CCDC17 coiled-coil domain containing 17
CCDC183 coiled-coil domain containing 183
CCDC57 coiled-coil domain containing 57
CCDC63 coiled-coil domain containing 63
CCDC97 coiled-coil domain containing 97
CD37 CD37 molecule
CDK11A cyclin-dependent kinase 11A
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CLDN25 claudin 25
CLUH clustered mitochondria (cluA/CLU1) homolog
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CPNE1 copine I
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CXCL16 chemokine (C-X-C motif) ligand 16
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DCST1 DC-STAMP domain containing 1
DEFB118 defensin, beta 118
DEFB119 defensin, beta 119
DEFB124 defensin, beta 124
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DPH1 diphthamide biosynthesis 1
DUSP27 dual specificity phosphatase 27 (putative)
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1
ELMO2 engulfment and cell motility 2
ENO3 enolase 3 (beta, muscle)
EPGN epithelial mitogen
EPOR erythropoietin receptor
EWSR1 EWS RNA-binding protein 1
FAM160B2 family with sequence similarity 160, member B2
FAM182B family with sequence similarity 182, member B
FAM193A family with sequence similarity 193, member A
FAM3B family with sequence similarity 3, member B
FAM83H family with sequence similarity 83, member H
FAM95B1 family with sequence similarity 95, member B1
FGD2 FYVE, RhoGEF and PH domain containing 2
FGF17 fibroblast growth factor 17
FGL1 fibrinogen-like 1
FLII flightless I homolog (Drosophila)
FLJ13224 uncharacterized LOC79857
FLJ37453 uncharacterized LOC729614
FOLR2 folate receptor 2 (fetal)
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
FSD2 fibronectin type III and SPRY domain containing 2
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAA glucosidase, alpha; acid
GAGE10 G antigen 10
GIMAP5 GTPase, IMAP family member 5
GLTSCR1 glioma tumor suppressor candidate region gene 1
GLUD2 glutamate dehydrogenase 2
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GOLGA6A golgin A6 family, member A
GOLGA6B golgin A6 family, member B
GOLGA6C golgin A6 family, member C
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP9 glycoprotein IX (platelet)
GPBAR1 G protein-coupled bile acid receptor 1
GPR153 G protein-coupled receptor 153
GRAMD1A GRAM domain containing 1A
GRIK5 glutamate receptor, ionotropic, kainate 5
GSTTP2 glutathione S-transferase theta pseudogene 2
GUSBP3 glucuronidase, beta pseudogene 3
HCFC1 host cell factor C1
HDGF hepatoma-derived growth factor
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HIC2 hypermethylated in cancer 2
HMGN5 high mobility group nucleosome binding domain 5
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HPSE heparanase
IFT140 intraflagellar transport 140
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
INPPL1 inositol polyphosphate phosphatase-like 1
IZUMO1 izumo sperm-egg fusion 1
JADE1 jade family PHD finger 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCTD11 potassium channel tetramerization domain containing 11
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KHSRP KH-type splicing regulatory protein
KLHL25 kelch-like family member 25
KLHL33 kelch-like family member 33
KLHL6 kelch-like family member 6
LHX1 LIM homeobox 1
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LINC00028 long intergenic non-protein coding RNA 28
LINC00235 long intergenic non-protein coding RNA 235
LINC00593 long intergenic non-protein coding RNA 593
LIPA lipase A, lysosomal acid, cholesterol esterase
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC100272216 uncharacterized LOC100272216
LOC284009 uncharacterized LOC284009
LOC440040 glutamate receptor, metabotropic 5 pseudogene
LOC613037 nuclear pore complex interacting protein pseudogene
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRC1 leucine rich repeat containing 1
LRRC39 leucine rich repeat containing 39
LUZP2 leucine zipper protein 2
MAMDC2 MAM domain containing 2
MAPT microtubule-associated protein tau
MED24 mediator complex subunit 24
MERTK MER proto-oncogene, tyrosine kinase
MEX3A mex-3 RNA binding family member A
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
MOCS3 molybdenum cofactor synthesis 3
MS4A7 membrane-spanning 4-domains, subfamily A, member 7
MSLN mesothelin
MYBBP1A MYB binding protein (P160) 1a
MYO1A myosin IA
MYO7A myosin VIIA
MYOZ2 myozenin 2
NBPF15 neuroblastoma breakpoint family, member 15
NCKAP5 NCK-associated protein 5
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NKD1 naked cuticle homolog 1 (Drosophila)
NLGN2 neuroligin 2
NME1-NME2 NME1-NME2 readthrough
NRBP2 nuclear receptor binding protein 2
NUTM2A NUT family member 2A
NUTM2D NUT family member 2D
OCM2 oncomodulin 2
OR3A4P olfactory receptor, family 3, subfamily A, member 4 pseudogene
OR5B3 olfactory receptor, family 5, subfamily B, member 3
OR5T1 olfactory receptor, family 5, subfamily T, member 1
OR7D4 olfactory receptor, family 7, subfamily D, member 4
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PAGE4 P antigen family, member 4 (prostate associated)
PCDHGA5 protocadherin gamma subfamily A, 5
PCDHGB6 protocadherin gamma subfamily B, 6
PCTP phosphatidylcholine transfer protein
PDGFC platelet derived growth factor C
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDZRN3 PDZ domain containing ring finger 3
PHLDB3 pleckstrin homology-like domain, family B, member 3
PI4KAP1 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
PLA2G12B phospholipase A2, group XIIB
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PMCHL2 pro-melanin-concentrating hormone-like 2, pseudogene
POLM polymerase (DNA directed), mu
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POU5F1 POU class 5 homeobox 1
PRAMEF8 PRAME family member 8
PRCC papillary renal cell carcinoma (translocation-associated)
PRDM14 PR domain containing 14
PRDM15 PR domain containing 15
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRPF38B pre-mRNA processing factor 38B
PRR12 proline rich 12
PRR30 proline rich 30
PSG6 pregnancy specific beta-1-glycoprotein 6
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASGRP4 RAS guanyl releasing protein 4
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGL3 ral guanine nucleotide dissociation stimulator-like 3
RNF222 ring finger protein 222
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SAMD13 sterile alpha motif domain containing 13
SCAF4 SR-related CTD-associated factor 4
SCRIB scribbled planar cell polarity protein
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SETD5 SET domain containing 5
SFXN2 sideroflexin 2
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SGSM2 small G protein signaling modulator 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SHPK sedoheptulokinase
SIGLEC11 sialic acid binding Ig-like lectin 11
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SIGLEC14 sialic acid binding Ig-like lectin 14
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC26A11 solute carrier family 26 (anion exchanger), member 11
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC35G5 solute carrier family 35, member G5
SLC35G6 solute carrier family 35, member G6
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SMG5 SMG5 nonsense mediated mRNA decay factor
SMIM21 small integral membrane protein 21
SMTNL1 smoothelin-like 1
SNORA40 small nucleolar RNA, H/ACA box 40
SNORA45A small nucleolar RNA, H/ACA box 45A
SNORA78 small nucleolar RNA, H/ACA box 78
SNORA80E small nucleolar RNA, H/ACA box 80E
SORBS3 sorbin and SH3 domain containing 3
SOX2 SRY (sex determining region Y)-box 2
SOX3 SRY (sex determining region Y)-box 3
SP2 Sp2 transcription factor
SPATC1 spermatogenesis and centriole associated 1
SPIN4 spindlin family, member 4
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRRM1 serine/arginine repetitive matrix 1
SRRM5 serine/arginine repetitive matrix 5
SRSF4 serine/arginine-rich splicing factor 4
SSPO SCO-spondin
STAT5B signal transducer and activator of transcription 5B
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1
SUMO1P1 SUMO1 pseudogene 1
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D3 TBC1 domain family, member 3
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCP11 t-complex 11, testis-specific
TDRP testis development related protein
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
TMC8 transmembrane channel-like 8
TMIGD2 transmembrane and immunoglobulin domain containing 2
TMPRSS11BNL TMPRSS11B N-terminal like, pseudogene
TMPRSS13 transmembrane protease, serine 13
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNIP2 TNFAIP3 interacting protein 2
TNK1 tyrosine kinase, non-receptor, 1
TPRX1 tetra-peptide repeat homeobox 1
TRIM50 tripartite motif containing 50
TRIM64 tripartite motif containing 64
TRIOBP TRIO and F-actin binding protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSNAX-DISC1 TSNAX-DISC1 readthrough (NMD candidate)
TSPAN14 tetraspanin 14
TSSK3 testis-specific serine kinase 3
TTC24 tetratricopeptide repeat domain 24
TTYH1 tweety family member 1
UBQLN4 ubiquilin 4
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UNC5CL unc-5 homolog C (C. elegans)-like
VIPR2 vasoactive intestinal peptide receptor 2
WDR81 WD repeat domain 81
XKR6 XK, Kell blood group complex subunit-related family, member 6
XYLT2 xylosyltransferase II
ZC3H4 zinc finger CCCH-type containing 4
ZDHHC19 zinc finger, DHHC-type containing 19
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZNF192P1 zinc finger protein 192 pseudogene 1
ZNF213 zinc finger protein 213
ZNF324B zinc finger protein 324B
ZNF337 zinc finger protein 337
ZNF512B zinc finger protein 512B
ZNF543 zinc finger protein 543
ZNF595 zinc finger protein 595
ZNF696 zinc finger protein 696
ZNF70 zinc finger protein 70
ZNF705D zinc finger protein 705D
ZNF707 zinc finger protein 707
ZNF710 zinc finger protein 710
ZNF835 zinc finger protein 835
ZSCAN5B zinc finger and SCAN domain containing 5B
ZSWIM5 zinc finger, SWIM-type containing 5
ZSWIM8 zinc finger, SWIM-type containing 8

low expression

Symbol Name
ASNSD1 asparagine synthetase domain containing 1
COPS8 COP9 signalosome subunit 8
FASTKD2 FAST kinase domains 2
MED7 mediator complex subunit 7
MRPS10 mitochondrial ribosomal protein S10
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
TXNDC9 thioredoxin domain containing 9