Brain Lower Grade Glioma_LGG_TCGA-E1-A7YH-01A-11R-A34F-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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393 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-E1-A7YH-01A-11R-A34F-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABHD6 abhydrolase domain containing 6
ACADVL acyl-CoA dehydrogenase, very long chain
ACRC acidic repeat containing
ACSM1 acyl-CoA synthetase medium-chain family member 1
ACTL7B actin-like 7B
ACTN2 actinin, alpha 2
ADAM32 ADAM metallopeptidase domain 32
ADCY10 adenylate cyclase 10 (soluble)
ADGRF3 adhesion G protein-coupled receptor F3
ADIPOR2 adiponectin receptor 2
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5
AHSA2 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)
AKAP4 A kinase (PRKA) anchor protein 4
AKT1S1 AKT1 substrate 1 (proline-rich)
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
ALOX15B arachidonate 15-lipoxygenase, type B
AMY2A amylase, alpha 2A (pancreatic)
AMY2B amylase, alpha 2B (pancreatic)
ANKRD40 ankyrin repeat domain 40
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANLN anillin, actin binding protein
ARHGAP21 Rho GTPase activating protein 21
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMC12 armadillo repeat containing 12
ASB15 ankyrin repeat and SOCS box containing 15
ASMTL-AS1 ASMTL antisense RNA 1
ATG13 autophagy related 13
ATG16L2 autophagy related 16-like 2 (S. cerevisiae)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
BCL2L15 BCL2-like 15
BCR breakpoint cluster region
BMP8A bone morphogenetic protein 8a
BOC BOC cell adhesion associated, oncogene regulated
BOK BCL2-related ovarian killer
C10ORF128 chromosome 10 open reading frame 128
C11ORF52 chromosome 11 open reading frame 52
C11ORF54 chromosome 11 open reading frame 54
C11ORF94 chromosome 11 open reading frame 94
C12ORF60 chromosome 12 open reading frame 60
C19ORF18 chromosome 19 open reading frame 18
C1ORF116 chromosome 1 open reading frame 116
C1ORF210 chromosome 1 open reading frame 210
C1QTNF8 C1q and tumor necrosis factor related protein 8
C2ORF78 chromosome 2 open reading frame 78
C5ORF60 chromosome 5 open reading frame 60
C6ORF25 chromosome 6 open reading frame 25
C6ORF52 chromosome 6 open reading frame 52
C9ORF43 chromosome 9 open reading frame 43
CAPN7 calpain 7
CBFB core-binding factor, beta subunit
CC2D1B coiled-coil and C2 domain containing 1B
CCDC54 coiled-coil domain containing 54
CCDC63 coiled-coil domain containing 63
CCDC82 coiled-coil domain containing 82
CCDC84 coiled-coil domain containing 84
CCND2 cyclin D2
CD22 CD22 molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDH20 cadherin 20, type 2
CDK19 cyclin-dependent kinase 19
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEP164 centrosomal protein 164kDa
CERCAM cerebral endothelial cell adhesion molecule
CERS3 ceramide synthase 3
CES4A carboxylesterase 4A
CHKA choline kinase alpha
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLDN6 claudin 6
CLDND1 claudin domain containing 1
CLEC16A C-type lectin domain family 16, member A
CLK1 CDC-like kinase 1
CLK4 CDC-like kinase 4
CLMN calmin (calponin-like, transmembrane)
CLTCL1 clathrin, heavy chain-like 1
CMTM2 CKLF-like MARVEL transmembrane domain containing 2
CNN2 calponin 2
CNTN3 contactin 3 (plasmacytoma associated)
COL4A6 collagen, type IV, alpha 6
COX6B2 cytochrome c oxidase subunit VIb polypeptide 2 (testis)
COX8C cytochrome c oxidase subunit VIIIC
CPOX coproporphyrinogen oxidase
CROCC ciliary rootlet coiled-coil, rootletin
CRYGA crystallin, gamma A
CSDC2 cold shock domain containing C2, RNA binding
CSNK1G2-AS1 CSNK1G2 antisense RNA 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CUZD1 CUB and zona pellucida-like domains 1
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DAGLB diacylglycerol lipase, beta
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DIO1 deiodinase, iodothyronine, type I
DNAH17 dynein, axonemal, heavy chain 17
DOCK5 dedicator of cytokinesis 5
DPRX divergent-paired related homeobox
EED embryonic ectoderm development
EFHD1 EF-hand domain family, member D1
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EPOR erythropoietin receptor
ERMARD ER membrane-associated RNA degradation
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FADS3 fatty acid desaturase 3
FAM19A4 family with sequence similarity 19 (chemokine (C-C motif)-like), member A4
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
FAM209B family with sequence similarity 209, member B
FAM214A family with sequence similarity 214, member A
FAM35A family with sequence similarity 35, member A
FAM35DP family with sequence similarity 35, member A pseudogene
FAM58A family with sequence similarity 58, member A
FAM71E2 family with sequence similarity 71, member E2
FAM71F2 family with sequence similarity 71, member F2
FBXO31 F-box protein 31
FBXW12 F-box and WD repeat domain containing 12
FFAR1 free fatty acid receptor 1
FGF23 fibroblast growth factor 23
FKBP6 FK506 binding protein 6, 36kDa
FLJ41941 uncharacterized LOC100192420
FLJ42393 uncharacterized LOC401105
FMR1NB fragile X mental retardation 1 neighbor
FOXD4 forkhead box D4
FOXD4L5 forkhead box D4-like 5
FOXO4 forkhead box O4
FRG2 FSHD region gene 2
FUT2 fucosyltransferase 2 (secretor status included)
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GAGE10 G antigen 10
GAGE2D G antigen 2D
GCDH glutaryl-CoA dehydrogenase
GEMIN8 gem (nuclear organelle) associated protein 8
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GGNBP2 gametogenetin binding protein 2
GIPR gastric inhibitory polypeptide receptor
GLIS1 GLIS family zinc finger 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNMT glycine N-methyltransferase
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
GPR62 G protein-coupled receptor 62
GPR89B G protein-coupled receptor 89B
GSTA2 glutathione S-transferase alpha 2
GUSBP3 glucuronidase, beta pseudogene 3
GYPA glycophorin A (MNS blood group)
H2AFB1 H2A histone family, member B1
HAPLN2 hyaluronan and proteoglycan link protein 2
HERC2P2 hect domain and RLD 2 pseudogene 2
HERC2P4 hect domain and RLD 2 pseudogene 4
HES4 hes family bHLH transcription factor 4
HGFAC HGF activator
HIGD1C HIG1 hypoxia inducible domain family, member 1C
HIST1H2AB histone cluster 1, H2ab
HIST1H4D histone cluster 1, H4d
HMGB4 high mobility group box 4
HMGN2P46 high mobility group nucleosomal binding domain 2 pseudogene 46
HPX hemopexin
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSP90AB4P heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene
IFNA6 interferon, alpha 6
ILDR1 immunoglobulin-like domain containing receptor 1
IMPG2 interphotoreceptor matrix proteoglycan 2
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
INPP5K inositol polyphosphate-5-phosphatase K
INSR insulin receptor
IP6K3 inositol hexakisphosphate kinase 3
IQCF5 IQ motif containing F5
IZUMO4 IZUMO family member 4
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
KDM6A lysine (K)-specific demethylase 6A
KIF19 kinesin family member 19
KIF1C kinesin family member 1C
KLF15 Kruppel-like factor 15
KLHL17 kelch-like family member 17
KRT74 keratin 74, type II
KRTAP10-12 keratin associated protein 10-12
LAMB4 laminin, beta 4
LEAP2 liver expressed antimicrobial peptide 2
LENG8 leukocyte receptor cluster (LRC) member 8
LINC00174 long intergenic non-protein coding RNA 174
LINC00479 long intergenic non-protein coding RNA 479
LINC00685 long intergenic non-protein coding RNA 685
LINC01554 long intergenic non-protein coding RNA 1554
LIPE lipase, hormone-sensitive
LOC100128573 uncharacterized LOC100128573
LOC100132287 uncharacterized LOC100132287
LOC100133331 uncharacterized LOC100133331
LOC391322 D-dopachrome tautomerase-like
LOC401127 WD repeat domain 5 pseudogene
LOC541473 FK506 binding protein 6, 36kDa pseudogene
LOC728989 phosphodiesterase 4D interacting protein pseudogene
LRP2 low density lipoprotein receptor-related protein 2
LRRC1 leucine rich repeat containing 1
LRRC19 leucine rich repeat containing 19
LYZL1 lysozyme-like 1
MAGEC3 melanoma antigen family C3
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP7 microtubule-associated protein 7
MBP myelin basic protein
MGC16025 uncharacterized LOC85009
MGC16142 uncharacterized protein MGC16142
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MROH9 maestro heat-like repeat family member 9
MSLNL mesothelin-like
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus)
MTUS1 microtubule associated tumor suppressor 1
MXI1 MAX interactor 1, dimerization protein
MYBPHL myosin binding protein H-like
NADSYN1 NAD synthetase 1
NANOS2 nanos homolog 2 (Drosophila)
NDRG1 N-myc downstream regulated 1
NEK3 NIMA-related kinase 3
NEXN nexilin (F actin binding protein)
NIPAL4 NIPA-like domain containing 4
NKX6-2 NK6 homeobox 2
NT5C2 5'-nucleotidase, cytosolic II
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUP54 nucleoporin 54kDa
NUTM2A NUT family member 2A
NYX nyctalopin
OFD1 oral-facial-digital syndrome 1
OR10A4 olfactory receptor, family 10, subfamily A, member 4
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4
OR2D2 olfactory receptor, family 2, subfamily D, member 2
OR4X2 olfactory receptor, family 4, subfamily X, member 2 (gene/pseudogene)
OR51L1 olfactory receptor, family 51, subfamily L, member 1
OR7A5 olfactory receptor, family 7, subfamily A, member 5
OR8B3 olfactory receptor, family 8, subfamily B, member 3
OR8U1 olfactory receptor, family 8, subfamily U, member 1
OTUD7B OTU deubiquitinase 7B
OXT oxytocin/neurophysin I prepropeptide
PAIP2B poly(A) binding protein interacting protein 2B
PCDHB18P protocadherin beta 18 pseudogene
PCTP phosphatidylcholine transfer protein
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDE8A phosphodiesterase 8A
PDILT protein disulfide isomerase-like, testis expressed
PER1 period circadian clock 1
PFN1P2 profilin 1 pseudogene 2
PHF19 PHD finger protein 19
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase
PI4KAP1 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
PICK1 protein interacting with PRKCA 1
PILRB paired immunoglobin-like type 2 receptor beta
PIWIL4 piwi-like RNA-mediated gene silencing 4
PLAC8L1 PLAC8-like 1
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLIN3 perilipin 3
PLXNB1 plexin B1
PNPLA2 patatin-like phospholipase domain containing 2
PNRC1 proline-rich nuclear receptor coactivator 1
POLN polymerase (DNA directed) nu
POM121L10P POM121 transmembrane nucleoporin-like 10, pseudogene
PP2D1 protein phosphatase 2C-like domain containing 1
PPIEL peptidylprolyl isomerase E-like pseudogene
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPP5C protein phosphatase 5, catalytic subunit
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRAMEF1 PRAME family member 1
PRCD progressive rod-cone degeneration
PRDM9 PR domain containing 9
PROM2 prominin 2
PRR14 proline rich 14
PRR18 proline rich 18
PXDC1 PX domain containing 1
RABGGTB Rab geranylgeranyltransferase, beta subunit
RAD52 RAD52 homolog (S. cerevisiae)
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBM5 RNA binding motif protein 5
REPS1 RALBP1 associated Eps domain containing 1
RGL3 ral guanine nucleotide dissociation stimulator-like 3
RGPD1 RANBP2-like and GRIP domain containing 1
RGS11 regulator of G-protein signaling 11
RNF222 ring finger protein 222
RPA4 replication protein A4, 30kDa
RSRP1 arginine/serine-rich protein 1
S1PR5 sphingosine-1-phosphate receptor 5
SAP30 Sin3A-associated protein, 30kDa
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEPP1 selenoprotein P, plasma, 1
SEPT12 septin 12
SEPT4 septin 4
SESN1 sestrin 1
SFR1 SWI5-dependent recombination repair 1
SGK1 serum/glucocorticoid regulated kinase 1
SGK3 serum/glucocorticoid regulated kinase family, member 3
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
SLC39A11 solute carrier family 39, member 11
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMAD7 SMAD family member 7
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMCO1 single-pass membrane protein with coiled-coil domains 1
SNAR-B2 small ILF3/NF90-associated RNA B2
SNORA10 small nucleolar RNA, H/ACA box 10
SNORA11 small nucleolar RNA, H/ACA box 11
SNORA11E small nucleolar RNA, H/ACA box 11E
SNORA13 small nucleolar RNA, H/ACA box 13
SNORA24 small nucleolar RNA, H/ACA box 24
SNORA25 small nucleolar RNA, H/ACA box 25
SNORA38B small nucleolar RNA, H/ACA box 38B
SNORA40 small nucleolar RNA, H/ACA box 40
SNORA45A small nucleolar RNA, H/ACA box 45A
SNORA52 small nucleolar RNA, H/ACA box 52
SNORA61 small nucleolar RNA, H/ACA box 61
SNORA72 small nucleolar RNA, H/ACA box 72
SNORA76C small nucleolar RNA, H/ACA box 76C
SNORA81 small nucleolar RNA, H/ACA box 81
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SPACA5 sperm acrosome associated 5
SPEM1 spermatid maturation 1
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SRPK3 SRSF protein kinase 3
SRSF5 serine/arginine-rich splicing factor 5
SSUH2 ssu-2 homolog (C. elegans)
STK17B serine/threonine kinase 17b
STK31 serine/threonine kinase 31
STPG2 sperm-tail PG-rich repeat containing 2
SUN2 Sad1 and UNC84 domain containing 2
SWT1 SWT1 RNA endoribonuclease homolog (S. cerevisiae)
TBATA thymus, brain and testes associated
TBC1D17 TBC1 domain family, member 17
TBC1D29 TBC1 domain family, member 29
TBC1D3 TBC1 domain family, member 3
TBX19 T-box 19
TBX2 T-box 2
TCEANC transcription elongation factor A (SII) N-terminal and central domain containing
TDRD12 tudor domain containing 12
TDRD6 tudor domain containing 6
TEX43 testis expressed 43
TFDP3 transcription factor Dp family, member 3
TFEB transcription factor EB
THOC1 THO complex 1
TJAP1 tight junction associated protein 1 (peripheral)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLR9 toll-like receptor 9
TMC6 transmembrane channel-like 6
TMCO2 transmembrane and coiled-coil domains 2
TMEM144 transmembrane protein 144
TMEM63A transmembrane protein 63A
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TP53INP2 tumor protein p53 inducible nuclear protein 2
TPCN2 two pore segment channel 2
TRA2A transformer 2 alpha homolog (Drosophila)
TRAF1 TNF receptor-associated factor 1
TRIM66 tripartite motif containing 66
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TSPYL2 TSPY-like 2
TUBE1 tubulin, epsilon 1
UBAP2 ubiquitin associated protein 2
UGT2B11 UDP glucuronosyltransferase 2 family, polypeptide B11
UNKL unkempt family zinc finger-like
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
VCAN versican
WASH5P WAS protein family homolog 5 pseudogene
WDR20 WD repeat domain 20
WDR45 WD repeat domain 45
XAGE5 X antigen family, member 5
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YPEL3 yippee-like 3 (Drosophila)
ZNF137P zinc finger protein 137, pseudogene
ZNF189 zinc finger protein 189
ZNF211 zinc finger protein 211
ZNF222 zinc finger protein 222
ZNF233 zinc finger protein 233
ZNF404 zinc finger protein 404
ZNF418 zinc finger protein 418
ZNF419 zinc finger protein 419
ZNF547 zinc finger protein 547
ZNF564 zinc finger protein 564
ZNF577 zinc finger protein 577
ZNF596 zinc finger protein 596
ZNF615 zinc finger protein 615
ZNF652 zinc finger protein 652
ZNF763 zinc finger protein 763
ZP3 zona pellucida glycoprotein 3 (sperm receptor)

low expression

Symbol Name
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PWP1 PWP1 homolog (S. cerevisiae)
UBE2N ubiquitin-conjugating enzyme E2N