Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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376 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADACL3 arylacetamide deacetylase-like 3
AADACL4 arylacetamide deacetylase-like 4
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ABHD17A abhydrolase domain containing 17A
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
ACSM2A acyl-CoA synthetase medium-chain family member 2A
ACSM5 acyl-CoA synthetase medium-chain family member 5
ACSS1 acyl-CoA synthetase short-chain family member 1
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADCK1 aarF domain containing kinase 1
ADCK4 aarF domain containing kinase 4
ADGRB1 adhesion G protein-coupled receptor B1
ADIPOR2 adiponectin receptor 2
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
AGBL3 ATP/GTP binding protein-like 3
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR7L aldo-keto reductase family 7-like (gene/pseudogene)
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANGPT4 angiopoietin 4
ANXA3 annexin A3
AQP8 aquaporin 8
ARHGAP39 Rho GTPase activating protein 39
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARL5C ADP-ribosylation factor-like 5C
ARMC12 armadillo repeat containing 12
ASIC5 acid sensing (proton gated) ion channel family member 5
ASMTL-AS1 ASMTL antisense RNA 1
ASPRV1 aspartic peptidase, retroviral-like 1
ATG4B autophagy related 4B, cysteine peptidase
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
BLM Bloom syndrome, RecQ helicase-like
BMP15 bone morphogenetic protein 15
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BTBD18 BTB (POZ) domain containing 18
C10ORF120 chromosome 10 open reading frame 120
C12ORF54 chromosome 12 open reading frame 54
C17ORF99 chromosome 17 open reading frame 99
C19ORF54 chromosome 19 open reading frame 54
C1ORF61 chromosome 1 open reading frame 61
C20ORF196 chromosome 20 open reading frame 196
C4ORF26 chromosome 4 open reading frame 26
C5ORF38 chromosome 5 open reading frame 38
C6ORF58 chromosome 6 open reading frame 58
C9ORF57 chromosome 9 open reading frame 57
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4
CCBL2 cysteine conjugate-beta lyase 2
CCDC17 coiled-coil domain containing 17
CCDC172 coiled-coil domain containing 172
CCDC27 coiled-coil domain containing 27
CCDC97 coiled-coil domain containing 97
CCNE1 cyclin E1
CD160 CD160 molecule
CD1D CD1d molecule
CD99 CD99 molecule
CDK10 cyclin-dependent kinase 10
CDK3 cyclin-dependent kinase 3
CFHR2 complement factor H-related 2
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CIT citron rho-interacting serine/threonine kinase
CLEC16A C-type lectin domain family 16, member A
CLTCL1 clathrin, heavy chain-like 1
COL23A1 collagen, type XXIII, alpha 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COPS7B COP9 signalosome subunit 7B
COX7B2 cytochrome c oxidase subunit VIIb2
CPA2 carboxypeptidase A2 (pancreatic)
CRIPAK cysteine-rich PAK1 inhibitor
CROCC ciliary rootlet coiled-coil, rootletin
CRYBB3 crystallin, beta B3
CST13P cystatin 13, pseudogene
CST9 cystatin 9 (testatin)
CT55 cancer/testis antigen 55
CTNNBIP1 catenin, beta interacting protein 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
D2HGDH D-2-hydroxyglutarate dehydrogenase
DCAF8L1 DDB1 and CUL4 associated factor 8-like 1
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
DEFB132 defensin, beta 132
DEXI Dexi homolog (mouse)
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DKK4 dickkopf WNT signaling pathway inhibitor 4
DMRTC2 DMRT-like family C2
DNASE1 deoxyribonuclease I
DNMBP-AS1 DNMBP antisense RNA 1
DPPA5 developmental pluripotency associated 5
EBF4 early B-cell factor 4
EGLN2 egl-9 family hypoxia-inducible factor 2
EHD1 EH-domain containing 1
ENOX2 ecto-NOX disulfide-thiol exchanger 2
ENTHD2 ENTH domain containing 2
ERICH6 glutamate-rich 6
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FABP12 fatty acid binding protein 12
FAM110A family with sequence similarity 110, member A
FAM193B family with sequence similarity 193, member B
FAM213A family with sequence similarity 213, member A
FAM214B family with sequence similarity 214, member B
FAM57B family with sequence similarity 57, member B
FBXO31 F-box protein 31
FBXW12 F-box and WD repeat domain containing 12
FIGLA folliculogenesis specific basic helix-loop-helix
FITM1 fat storage-inducing transmembrane protein 1
FLJ13224 uncharacterized LOC79857
FOXD3 forkhead box D3
FOXD4L3 forkhead box D4-like 3
FTH1P3 ferritin, heavy polypeptide 1 pseudogene 3
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GAGE8 G antigen 8
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GATSL3 GATS protein-like 3
GDF1 growth differentiation factor 1
GGTA1P glycoprotein, alpha-galactosyltransferase 1 pseudogene
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
GPKOW G patch domain and KOW motifs
GPR88 G protein-coupled receptor 88
GPX6 glutathione peroxidase 6
GSTM2 glutathione S-transferase mu 2 (muscle)
H1FNT H1 histone family, member N, testis-specific
H1FX-AS1 H1FX antisense RNA 1
H2BFXP H2B histone family, member X, pseudogene
HAPLN2 hyaluronan and proteoglycan link protein 2
HGFAC HGF activator
HIF3A hypoxia inducible factor 3, alpha subunit
HMGB3P1 high mobility group box 3 pseudogene 1
HMHB1 histocompatibility (minor) HB-1
HMOX2 heme oxygenase 2
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
HRSP12 heat-responsive protein 12
HSFY2 heat shock transcription factor, Y linked 2
HTATSF1 HIV-1 Tat specific factor 1
HTRA1 HtrA serine peptidase 1
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B
IFNA4 interferon, alpha 4
IGSF3 immunoglobulin superfamily, member 3
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
IP6K2 inositol hexakisphosphate kinase 2
ISX intestine-specific homeobox
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KBTBD13 kelch repeat and BTB (POZ) domain containing 13
KIAA2013 KIAA2013
KIF19 kinesin family member 19
KLHDC8B kelch domain containing 8B
KLK12 kallikrein-related peptidase 12
KRT28 keratin 28, type I
KRTAP12-2 keratin associated protein 12-2
KRTAP13-1 keratin associated protein 13-1
KRTAP24-1 keratin associated protein 24-1
KRTAP5-7 keratin associated protein 5-7
LCE4A late cornified envelope 4A
LCNL1 lipocalin-like 1
LEFTY1 left-right determination factor 1
LHB luteinizing hormone beta polypeptide
LINC00029 long intergenic non-protein coding RNA 29
LINC00051 long intergenic non-protein coding RNA 51
LINC00114 long intergenic non-protein coding RNA 114
LINC00161 long intergenic non-protein coding RNA 161
LINC00685 long intergenic non-protein coding RNA 685
LINC00852 long intergenic non-protein coding RNA 852
LMBR1L limb development membrane protein 1-like
LOC100192426 uncharacterized LOC100192426
LOC100271832 uncharacterized LOC100271832
LOC100288778 WAS protein family homolog 1 pseudogene
LOC284788 uncharacterized LOC284788
LOC285074 anaphase promoting complex subunit 1 pseudogene
LOC285593 uncharacterized LOC285593
LOC285847 uncharacterized LOC285847
LOC440461 Rho GTPase activating protein 27 pseudogene
LOC646471 uncharacterized LOC646471
LOC91450 uncharacterized LOC91450
LOXL2 lysyl oxidase-like 2
LPL lipoprotein lipase
LPPR3 lipid phosphate phosphatase-related protein type 3
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
LRRC24 leucine rich repeat containing 24
LRRC27 leucine rich repeat containing 27
LRRC37A3 leucine rich repeat containing 37, member A3
LTB4R leukotriene B4 receptor
LTBP4 latent transforming growth factor beta binding protein 4
LUZP4 leucine zipper protein 4
LY6G5B lymphocyte antigen 6 complex, locus G5B
MAGEA5 melanoma antigen family A5
MAGED1 melanoma antigen family D1
MAGED4 melanoma antigen family D4
MAGED4B melanoma antigen family D4B
MAVS mitochondrial antiviral signaling protein
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCCD1 mitochondrial coiled-coil domain 1
MCTS2P malignant T cell amplified sequence 2, pseudogene
MIA2 melanoma inhibitory activity 2
MIIP migration and invasion inhibitory protein
MME membrane metallo-endopeptidase
MROH9 maestro heat-like repeat family member 9
MT1IP metallothionein 1I, pseudogene
MTFR1L mitochondrial fission regulator 1-like
MTMR14 myotubularin related protein 14
MTVR2 mouse mammary tumor virus receptor homolog 2
MXD4 MAX dimerization protein 4
MYOM2 myomesin 2
N4BP2L1 NEDD4 binding protein 2-like 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NEK3 NIMA-related kinase 3
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NOP56 NOP56 ribonucleoprotein
NPFF neuropeptide FF-amide peptide precursor
NPIPB3 nuclear pore complex interacting protein family, member B3
NPVF neuropeptide VF precursor
NXF4 nuclear RNA export factor 4 pseudogene
NYNRIN NYN domain and retroviral integrase containing
OR10G4 olfactory receptor, family 10, subfamily G, member 4
OR10K1 olfactory receptor, family 10, subfamily K, member 1
OR11H4 olfactory receptor, family 11, subfamily H, member 4
OR13C4 olfactory receptor, family 13, subfamily C, member 4
OR13F1 olfactory receptor, family 13, subfamily F, member 1
OR13J1 olfactory receptor, family 13, subfamily J, member 1
OR1A1 olfactory receptor, family 1, subfamily A, member 1
OR1D4 olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene)
OR1J2 olfactory receptor, family 1, subfamily J, member 2
OR1L6 olfactory receptor, family 1, subfamily L, member 6
OR1N1 olfactory receptor, family 1, subfamily N, member 1
OR2AK2 olfactory receptor, family 2, subfamily AK, member 2
OR2D2 olfactory receptor, family 2, subfamily D, member 2
OR2T5 olfactory receptor, family 2, subfamily T, member 5
OR2W1 olfactory receptor, family 2, subfamily W, member 1
OR4K2 olfactory receptor, family 4, subfamily K, member 2
OR51I2 olfactory receptor, family 51, subfamily I, member 2
OR51T1 olfactory receptor, family 51, subfamily T, member 1
OR52E2 olfactory receptor, family 52, subfamily E, member 2
OR52L1 olfactory receptor, family 52, subfamily L, member 1
OR5A1 olfactory receptor, family 5, subfamily A, member 1
OR6V1 olfactory receptor, family 6, subfamily V, member 1
OR8H2 olfactory receptor, family 8, subfamily H, member 2
OR8H3 olfactory receptor, family 8, subfamily H, member 3
OR9Q2 olfactory receptor, family 9, subfamily Q, member 2
OSGEP O-sialoglycoprotein endopeptidase
OTOP1 otopetrin 1
OVGP1 oviductal glycoprotein 1, 120kDa
OXSM 3-oxoacyl-ACP synthase, mitochondrial
PANK2 pantothenate kinase 2
PAPL iron/zinc purple acid phosphatase-like protein
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAX4 paired box 4
PDE8B phosphodiesterase 8B
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POM121L10P POM121 transmembrane nucleoporin-like 10, pseudogene
PPAN-P2RY11 PPAN-P2RY11 readthrough
PPIAL4D peptidylprolyl isomerase A (cyclophilin A)-like 4D
PPT2 palmitoyl-protein thioesterase 2
PRAMEF14 PRAME family member 14
PRAMEF8 PRAME family member 8
PRB2 proline-rich protein BstNI subfamily 2
PRG1 p53-responsive gene 1
PRKX protein kinase, X-linked
PRODH proline dehydrogenase (oxidase) 1
PRR5 proline rich 5 (renal)
PRX periaxin
PSG6 pregnancy specific beta-1-glycoprotein 6
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PSPN persephin
QARS glutaminyl-tRNA synthetase
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB19 RAB19, member RAS oncogene family
RAET1L retinoic acid early transcript 1L
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBMXL2 RNA binding motif protein, X-linked-like 2
REP15 RAB15 effector protein
REPS1 RALBP1 associated Eps domain containing 1
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene
RGS21 regulator of G-protein signaling 21
RHBDL3 rhomboid, veinlet-like 3 (Drosophila)
RHOXF1 Rhox homeobox family, member 1
RNF151 ring finger protein 151
RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing)
RPL13AP17 ribosomal protein L13a pseudogene 17
RPL22 ribosomal protein L22
RPL23AP32 ribosomal protein L23a pseudogene 32
RPSAP9 ribosomal protein SA pseudogene 9
SAFB2 scaffold attachment factor B2
SAMD13 sterile alpha motif domain containing 13
SCARNA12 small Cajal body-specific RNA 12
SCARNA9L small Cajal body-specific RNA 9-like
SCGB1C1 secretoglobin, family 1C, member 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13
SLC22A14 solute carrier family 22, member 14
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A38 solute carrier family 25, member 38
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC35E4 solute carrier family 35, member E4
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2
SLC39A11 solute carrier family 39, member 11
SLC51A solute carrier family 51, alpha subunit
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9C1 solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
SLITRK4 SLIT and NTRK-like family, member 4
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMOX spermine oxidase
SNHG3 small nucleolar RNA host gene 3
SNORA11D small nucleolar RNA, H/ACA box 11D
SNORA25 small nucleolar RNA, H/ACA box 25
SNORA29 small nucleolar RNA, H/ACA box 29
SNORA37 small nucleolar RNA, H/ACA box 37
SNORA45A small nucleolar RNA, H/ACA box 45A
SNORA59B small nucleolar RNA, H/ACA box 59B
SNORA61 small nucleolar RNA, H/ACA box 61
SNORA75 small nucleolar RNA, H/ACA box 75
SNX22 sorting nexin 22
SOX12 SRY (sex determining region Y)-box 12
SPACA7 sperm acrosome associated 7
SPATA16 spermatogenesis associated 16
SPEG SPEG complex locus
SPRR4 small proline-rich protein 4
SSUH2 ssu-2 homolog (C. elegans)
STK19 serine/threonine kinase 19
TAAR2 trace amine associated receptor 2
TAAR5 trace amine associated receptor 5
TAS2R50 taste receptor, type 2, member 50
TAS2R8 taste receptor, type 2, member 8
TBC1D3 TBC1 domain family, member 3
TBC1D3B TBC1 domain family, member 3B
TBC1D3C TBC1 domain family, member 3C
TBPL2 TATA box binding protein like 2
TGM6 transglutaminase 6
TMC6 transmembrane channel-like 6
TMCO2 transmembrane and coiled-coil domains 2
TMEM52 transmembrane protein 52
TMEM88B transmembrane protein 88B
TMEM89 transmembrane protein 89
TMEM91 transmembrane protein 91
TMEM95 transmembrane protein 95
TMPRSS12 transmembrane (C-terminal) protease, serine 12
TOP3B topoisomerase (DNA) III beta
TPCN1 two pore segment channel 1
TPGS1 tubulin polyglutamylase complex subunit 1
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
TRAPPC12 trafficking protein particle complex 12
TRIM40 tripartite motif containing 40
TRIM50 tripartite motif containing 50
TRIM53AP tripartite motif containing 53A, pseudogene
TRNP1 TMF1-regulated nuclear protein 1
TSPYL2 TSPY-like 2
TTTY14 testis-specific transcript, Y-linked 14 (non-protein coding)
UBE2DNL ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene)
UBOX5 U-box domain containing 5
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
VWCE von Willebrand factor C and EGF domains
WDR6 WD repeat domain 6
WFDC3 WAP four-disulfide core domain 3
WFDC8 WAP four-disulfide core domain 8
WISP2 WNT1 inducible signaling pathway protein 2
WISP3 WNT1 inducible signaling pathway protein 3
ZGLP1 zinc finger, GATA-like protein 1
ZNF343 zinc finger protein 343
ZNF652 zinc finger protein 652
ZNF771 zinc finger protein 771
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2

low expression

Symbol Name
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
FOXRED2 FAD-dependent oxidoreductase domain containing 2
MIEF1 mitochondrial elongation factor 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6