Brain Lower Grade Glioma_LGG_TCGA-FG-A4MW-01A-11R-A26U-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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434 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-FG-A4MW-01A-11R-A26U-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABHD17A abhydrolase domain containing 17A
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
ACTL7A actin-like 7A
ACTN4 actinin, alpha 4
ADAM15 ADAM metallopeptidase domain 15
ADAM33 ADAM metallopeptidase domain 33
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADAT3 adenosine deaminase, tRNA-specific 3
ADCK4 aarF domain containing kinase 4
ADCY10 adenylate cyclase 10 (soluble)
ADGRF2 adhesion G protein-coupled receptor F2
AFAP1L1 actin filament associated protein 1-like 1
AFMID arylformamidase
AGRN agrin
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
AKT1S1 AKT1 substrate 1 (proline-rich)
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH16A1 aldehyde dehydrogenase 16 family, member A1
ALG6 ALG6, alpha-1,3-glucosyltransferase
AP1M1 adaptor-related protein complex 1, mu 1 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
ARGFX arginine-fifty homeobox
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ART1 ADP-ribosyltransferase 1
ASB15 ankyrin repeat and SOCS box containing 15
ATAD3C ATPase family, AAA domain containing 3C
ATG4D autophagy related 4D, cysteine peptidase
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
BAX BCL2-associated X protein
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3
BRAT1 BRCA1-associated ATM activator 1
BSG basigin (Ok blood group)
C19ORF47 chromosome 19 open reading frame 47
C19ORF48 chromosome 19 open reading frame 48
C19ORF52 chromosome 19 open reading frame 52
C19ORF73 chromosome 19 open reading frame 73
C1ORF159 chromosome 1 open reading frame 159
C2ORF66 chromosome 2 open reading frame 66
C8ORF48 chromosome 8 open reading frame 48
CADM4 cell adhesion molecule 4
CAPNS1 calpain, small subunit 1
CBR1 carbonyl reductase 1
CCDC102B coiled-coil domain containing 102B
CCDC152 coiled-coil domain containing 152
CCDC61 coiled-coil domain containing 61
CCNB1 cyclin B1
CCNE1 cyclin E1
CD200R1L CD200 receptor 1-like
CD320 CD320 molecule
CD82 CD82 molecule
CDA cytidine deaminase
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDR2L cerebellar degeneration-related protein 2-like
CENPV centromere protein V
CERCAM cerebral endothelial cell adhesion molecule
CGB8 chorionic gonadotropin, beta polypeptide 8
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLEC18C C-type lectin domain family 18, member C
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
CLPTM1 cleft lip and palate associated transmembrane protein 1
COL16A1 collagen, type XVI, alpha 1
COL20A1 collagen, type XX, alpha 1
COL27A1 collagen, type XXVII, alpha 1
COL5A2 collagen, type V, alpha 2
COL5A3 collagen, type V, alpha 3
COL9A2 collagen, type IX, alpha 2
COL9A3 collagen, type IX, alpha 3
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CPEB2 cytoplasmic polyadenylation element binding protein 2
CPNE4 copine IV
CSNK1G2 casein kinase 1, gamma 2
CTAG1B cancer/testis antigen 1B
CTAG2 cancer/testis antigen 2
CTRB2 chymotrypsinogen B2
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DCAF15 DDB1 and CUL4 associated factor 15
DCAF4L2 DDB1 and CUL4 associated factor 4-like 2
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DEDD2 death effector domain containing 2
DMPK dystrophia myotonica-protein kinase
DMRTA2 DMRT-like family A2
DMRTC2 DMRT-like family C2
DMWD dystrophia myotonica, WD repeat containing
DOCK6 dedicator of cytokinesis 6
DPP4 dipeptidyl-peptidase 4
DSEL dermatan sulfate epimerase-like
EGFR epidermal growth factor receptor
EGLN2 egl-9 family hypoxia-inducible factor 2
EHD2 EH-domain containing 2
EIF3C eukaryotic translation initiation factor 3, subunit C
ELAVL1 ELAV like RNA binding protein 1
ELF5 E74-like factor 5 (ets domain transcription factor)
ELOVL2 ELOVL fatty acid elongase 2
EMC10 ER membrane protein complex subunit 10
EMP3 epithelial membrane protein 3
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERF Ets2 repressor factor
ETV2 ets variant 2
EVPLL envoplakin-like
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM109B family with sequence similarity 109, member B
FAM3C family with sequence similarity 3, member C
FAM46B family with sequence similarity 46, member B
FAM73B family with sequence similarity 73, member B
FBN3 fibrillin 3
FBXO17 F-box protein 17
FHL3 four and a half LIM domains 3
FIBIN fin bud initiation factor homolog (zebrafish)
FIZ1 FLT3-interacting zinc finger 1
FKBP5 FK506 binding protein 5
FREM2 FRAS1 related extracellular matrix protein 2
FSCN1 fascin actin-bundling protein 1
FUCA2 fucosidase, alpha-L- 2, plasma
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAS1 growth arrest-specific 1
GCAT glycine C-acetyltransferase
GFI1B growth factor independent 1B transcription repressor
GIPC1 GIPC PDZ domain containing family, member 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRB10 growth factor receptor-bound protein 10
GRB14 growth factor receptor-bound protein 14
GRWD1 glutamate-rich WD repeat containing 1
HCG9 HLA complex group 9 (non-protein coding)
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HHATL hedgehog acyltransferase-like
HILS1 histone linker H1 domain, spermatid-specific 1, pseudogene
HIST1H4K histone cluster 1, H4k
HIST1H4L histone cluster 1, H4l
HMG20B high mobility group 20B
HOMER3 homer scaffolding protein 3
HOXC10 homeobox C10
HSP90AB4P heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
HYAL2 hyaluronoglucosaminidase 2
IFNE interferon, epsilon
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL1RAP interleukin 1 receptor accessory protein
ILVBL ilvB (bacterial acetolactate synthase)-like
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INAFM1 InaF-motif containing 1
ING2 inhibitor of growth family, member 2
INTS1 integrator complex subunit 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
ISOC2 isochorismatase domain containing 2
ITGA10 integrin, alpha 10
ITPKC inositol-trisphosphate 3-kinase C
IZUMO2 IZUMO family member 2
JOSD2 Josephin domain containing 2
KAZN kazrin, periplakin interacting protein
KCNIP4-IT1 KCNIP4 intronic transcript 1
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KIAA0226L KIAA0226-like
KIF19 kinesin family member 19
KPTN kaptin (actin binding protein)
KRBA1 KRAB-A domain containing 1
KRT73 keratin 73, type II
KRTAP5-11 keratin associated protein 5-11
LAMB3 laminin, beta 3
LEF1 lymphoid enhancer-binding factor 1
LIG1 ligase I, DNA, ATP-dependent
LIPE lipase, hormone-sensitive
LMF2 lipase maturation factor 2
LOC200726 hCG1657980
LOC341056 SUMO1 activating enzyme subunit 1 pseudogene
LOC644936 actin, beta pseudogene
LONP1 lon peptidase 1, mitochondrial
LRP3 low density lipoprotein receptor-related protein 3
LRRC17 leucine rich repeat containing 17
LRRC4B leucine rich repeat containing 4B
LRRN2 leucine rich repeat neuronal 2
LTBP4 latent transforming growth factor beta binding protein 4
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MBD3 methyl-CpG binding domain protein 3
MCF2L MCF.2 cell line derived transforming sequence-like
MDM4 MDM4, p53 regulator
MED16 mediator complex subunit 16
MED25 mediator complex subunit 25
MEX3D mex-3 RNA binding family member D
MFSD10 major facilitator superfamily domain containing 10
MFSD2A major facilitator superfamily domain containing 2A
MIER2 mesoderm induction early response 1, family member 2
MIR155HG MIR155 host gene
MKNK2 MAP kinase interacting serine/threonine kinase 2
MMP2 matrix metallopeptidase 2
MOGAT1 monoacylglycerol O-acyltransferase 1
MOGAT2 monoacylglycerol O-acyltransferase 2
MPV17L2 MPV17 mitochondrial membrane protein-like 2
MRPL34 mitochondrial ribosomal protein L34
MRPS12 mitochondrial ribosomal protein S12
MYBPC3 myosin binding protein C, cardiac
MYO9B myosin IXB
NCAN neurocan
NCLN nicalin
NCMAP noncompact myelin associated protein
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NIPSNAP3A nipsnap homolog 3A (C. elegans)
NKX2-5 NK2 homeobox 5
NLRP13 NLR family, pyrin domain containing 13
NPY2R neuropeptide Y receptor Y2
NT5E 5'-nucleotidase, ecto (CD73)
NUCB1 nucleobindin 1
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19
NUTM1 NUT midline carcinoma, family member 1
NXPE4 neurexophilin and PC-esterase domain family, member 4
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OR11A1 olfactory receptor, family 11, subfamily A, member 1
OR1L1 olfactory receptor, family 1, subfamily L, member 1
OR1L3 olfactory receptor, family 1, subfamily L, member 3
OR4D6 olfactory receptor, family 4, subfamily D, member 6
OR52I2 olfactory receptor, family 52, subfamily I, member 2
OR52N2 olfactory receptor, family 52, subfamily N, member 2
OR5C1 olfactory receptor, family 5, subfamily C, member 1
PADI1 peptidyl arginine deiminase, type I
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARVB parvin, beta
PAX4 paired box 4
PBK PDZ binding kinase
PCDHA10 protocadherin alpha 10
PCDHB7 protocadherin beta 7
PDILT protein disulfide isomerase-like, testis expressed
PEPD peptidase D
PER4 period circadian clock 3 pseudogene
PGAM2 phosphoglycerate mutase 2 (muscle)
PGPEP1 pyroglutamyl-peptidase I
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PLLP plasmolipin
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PNKP polynucleotide kinase 3'-phosphatase
POC1A POC1 centriolar protein A
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLR1D polymerase (RNA) I polypeptide D, 16kDa
POLRMT polymerase (RNA) mitochondrial (DNA directed)
POTEG POTE ankyrin domain family, member G
POU4F1 POU class 4 homeobox 1
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPP1R12C protein phosphatase 1, regulatory subunit 12C
PPP1R15B protein phosphatase 1, regulatory subunit 15B
PPP5C protein phosphatase 5, catalytic subunit
PRICKLE3 prickle homolog 3 (Drosophila)
PRMT1 protein arginine methyltransferase 1
PRODH2 proline dehydrogenase (oxidase) 2
PROP1 PROP paired-like homeobox 1
PRPF31 pre-mRNA processing factor 31
PRSS48 protease, serine, 48
PSG4 pregnancy specific beta-1-glycoprotein 4
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PTPRH protein tyrosine phosphatase, receptor type, H
PTTG1 pituitary tumor-transforming 1
PUSL1 pseudouridylate synthase-like 1
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
PYY2 peptide YY, 2 (pseudogene)
QPCTL glutaminyl-peptide cyclotransferase-like
RAB4B RAB4B, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RAET1E retinoic acid early transcript 1E
RBM42 RNA binding motif protein 42
RP1 retinitis pigmentosa 1 (autosomal dominant)
RPS26P11 ribosomal protein S26 pseudogene 11
RUVBL2 RuvB-like AAA ATPase 2
S100A3 S100 calcium binding protein A3
SAE1 SUMO1 activating enzyme subunit 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEPW1 selenoprotein W, 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIRT2 sirtuin 2
SLC12A9 solute carrier family 12, member 9
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC39A3 solute carrier family 39 (zinc transporter), member 3
SLC7A5P2 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMG9 SMG9 nonsense mediated mRNA decay factor
SMIM21 small integral membrane protein 21
SMYD1 SET and MYND domain containing 1
SNAI2 snail family zinc finger 2
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNORA5C small nucleolar RNA, H/ACA box 5C
SOD3 superoxide dismutase 3, extracellular
SPACA4 sperm acrosome associated 4
SPINK9 serine peptidase inhibitor, Kazal type 9
SPPL2B signal peptide peptidase like 2B
SPRY4 sprouty homolog 4 (Drosophila)
STRN4 striatin, calmodulin binding protein 4
SYCN syncollin
TAAR6 trace amine associated receptor 6
TBATA thymus, brain and testes associated
TBCB tubulin folding cofactor B
TBX1 T-box 1
TBX2 T-box 2
TCF23 transcription factor 23
TGFB3 transforming growth factor, beta 3
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TMC6 transmembrane channel-like 6
TMEM133 transmembrane protein 133
TMEM140 transmembrane protein 140
TMEM147 transmembrane protein 147
TMEM161A transmembrane protein 161A
TMEM178A transmembrane protein 178A
TMEM201 transmembrane protein 201
TMEM204 transmembrane protein 204
TMEM205 transmembrane protein 205
TMEM211 transmembrane protein 211
TMEM259 transmembrane protein 259
TMPRSS11B transmembrane protease, serine 11B
TMTC4 transmembrane and tetratricopeptide repeat containing 4
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TNN tenascin N
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TP73-AS1 TP73 antisense RNA 1
TRIB2 tribbles pseudokinase 2
TRIM10 tripartite motif containing 10
TRIM28 tripartite motif containing 28
TROAP trophinin associated protein
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSEN34 TSEN34 tRNA splicing endonuclease subunit
TUBA1C tubulin, alpha 1c
TYK2 tyrosine kinase 2
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBE2S ubiquitin-conjugating enzyme E2S
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
WDR62 WD repeat domain 62
WNK4 WNK lysine deficient protein kinase 4
YDJC YdjC homolog (bacterial)
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZDHHC14 zinc finger, DHHC-type containing 14
ZFAT-AS1 ZFAT antisense RNA 1
ZFP57 ZFP57 zinc finger protein
ZNF155 zinc finger protein 155
ZNF416 zinc finger protein 416
ZNF480 zinc finger protein 480
ZNF524 zinc finger protein 524
ZNF530 zinc finger protein 530
ZNF544 zinc finger protein 544
ZNF598 zinc finger protein 598
ZNF615 zinc finger protein 615
ZNF628 zinc finger protein 628
ZNF71 zinc finger protein 71
ZNF784 zinc finger protein 784
ZNF83 zinc finger protein 83

low expression

Symbol Name
ADAL adenosine deaminase-like
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ASB7 ankyrin repeat and SOCS box containing 7
BAHD1 bromo adjacent homology domain containing 1
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
C15ORF57 chromosome 15 open reading frame 57
CCDC120 coiled-coil domain containing 120
CCDC127 coiled-coil domain containing 127
CCDC7 coiled-coil domain containing 7
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
DET1 de-etiolated homolog 1 (Arabidopsis)
EID1 EP300 interacting inhibitor of differentiation 1
EMC4 ER membrane protein complex subunit 4
FAM103A1 family with sequence similarity 103, member A1
FAM219B family with sequence similarity 219, member B
FAM45A family with sequence similarity 45, member A
FASTKD3 FAST kinase domains 3
FLJ10038 uncharacterized protein FLJ10038
GDPGP1 GDP-D-glucose phosphorylase 1
HMG20A high mobility group 20A
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
ICE1 interactor of little elongation complex ELL subunit 1
ICE2 interactor of little elongation complex ELL subunit 2
LCMT2 leucine carboxyl methyltransferase 2
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LINS lines homolog (Drosophila)
MEIS2 Meis homeobox 2
METTL25 methyltransferase like 25
MFAP1 microfibrillar-associated protein 1
MORF4 mortality factor 4 (pseudogene)
MORF4L1 mortality factor 4 like 1
MPI mannose phosphate isomerase
NDNL2 necdin-like 2
NME6 NME/NM23 nucleoside diphosphate kinase 6
NOLC1 nucleolar and coiled-body phosphoprotein 1
PACRGL PARK2 co-regulated-like
PDCD6 programmed cell death 6
PDCD7 programmed cell death 7
RAB11A RAB11A, member RAS oncogene family
RNF111 ring finger protein 111
RPP30 ribonuclease P/MRP 30kDa subunit
RRAGA Ras-related GTP binding A
RSL24D1 ribosomal L24 domain containing 1
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
SAR1A secretion associated, Ras related GTPase 1A
SENP8 SUMO/sentrin specific peptidase family member 8
SIN3A SIN3 transcription regulator family member A
SLTM SAFB-like, transcription modulator
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPATA5L1 spermatogenesis associated 5-like 1
TM2D3 TM2 domain containing 3
TRIQK triple QxxK/R motif containing
TUBGCP5 tubulin, gamma complex associated protein 5
UBE3A ubiquitin protein ligase E3A
UBR1 ubiquitin protein ligase E3 component n-recognin 1
VPS33B vacuolar protein sorting 33 homolog B (yeast)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VWA9 von Willebrand factor A domain containing 9
WAC WW domain containing adaptor with coiled-coil
WAPAL wings apart-like homolog (Drosophila)
ZNF280B zinc finger protein 280B
ZNF280D zinc finger protein 280D
ZNF770 zinc finger protein 770
ZSCAN29 zinc finger and SCAN domain containing 29