Brain Lower Grade Glioma_LGG_TCGA-FG-A70Z-01A-12R-A33Z-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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416 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-FG-A70Z-01A-12R-A33Z-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCC6P1 ATP-binding cassette, sub-family C, member 6 pseudogene 1 (functional)
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACP2 acid phosphatase 2, lysosomal
ACTL10 actin-like 10
ACTRT1 actin-related protein T1
ACTRT2 actin-related protein T2
ACVRL1 activin A receptor type II-like 1
ADGRG1 adhesion G protein-coupled receptor G1
ADGRL4 adhesion G protein-coupled receptor L4
AGMO alkylglycerol monooxygenase
ANAPC10 anaphase promoting complex subunit 10
ANGPT2 angiopoietin 2
ANKRD35 ankyrin repeat domain 35
ANXA2R annexin A2 receptor
AOX1 aldehyde oxidase 1
APLN apelin
APOC2 apolipoprotein C-II
AQP1 aquaporin 1 (Colton blood group)
ARHGAP27 Rho GTPase activating protein 27
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARID3C AT rich interactive domain 3C (BRIGHT-like)
ARMC10 armadillo repeat containing 10
ATP2A3 ATPase, Ca++ transporting, ubiquitous
AVPR1A arginine vasopressin receptor 1A
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCAS4 breast carcinoma amplified sequence 4
BCL6B B-cell CLL/lymphoma 6, member B
BCYRN1 brain cytoplasmic RNA 1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BPGM 2,3-bisphosphoglycerate mutase
BSND barttin CLCNK-type chloride channel accessory beta subunit
C10ORF91 chromosome 10 open reading frame 91
C12ORF74 chromosome 12 open reading frame 74
C14ORF142 chromosome 14 open reading frame 142
C17ORF50 chromosome 17 open reading frame 50
C17ORF64 chromosome 17 open reading frame 64
C1ORF185 chromosome 1 open reading frame 185
C1ORF53 chromosome 1 open reading frame 53
C21ORF62 chromosome 21 open reading frame 62
C22ORF31 chromosome 22 open reading frame 31
C2ORF82 chromosome 2 open reading frame 82
C3ORF36 chromosome 3 open reading frame 36
C9ORF170 chromosome 9 open reading frame 170
CA3 carbonic anhydrase III
CA5A carbonic anhydrase VA, mitochondrial
CAPN8 calpain 8
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CBWD1 COBW domain containing 1
CD101 CD101 molecule
CD3EAP CD3e molecule, epsilon associated protein
CD82 CD82 molecule
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDCA7L cell division cycle associated 7-like
CDH22 cadherin 22, type 2
CDH5 cadherin 5, type 2 (vascular endothelium)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEACAM20 carcinoembryonic antigen-related cell adhesion molecule 20
CENPM centromere protein M
CETP cholesteryl ester transfer protein, plasma
CFD complement factor D (adipsin)
CFL1P1 cofilin 1 (non-muscle) pseudogene 1
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CIAPIN1 cytokine induced apoptosis inhibitor 1
CLDN5 claudin 5
CLEC11A C-type lectin domain family 11, member A
CLEC14A C-type lectin domain family 14, member A
CLIC3 chloride intracellular channel 3
CLIC5 chloride intracellular channel 5
CMC1 C-x(9)-C motif containing 1
COG8 component of oligomeric golgi complex 8
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COLEC11 collectin sub-family member 11
COTL1 coactosin-like F-actin binding protein 1
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CPTP ceramide-1-phosphate transfer protein
CRCP CGRP receptor component
CRYGD crystallin, gamma D
CRYM-AS1 CRYM antisense RNA 1
CSAG1 chondrosarcoma associated gene 1
CUX1 cut-like homeobox 1
CXORF36 chromosome X open reading frame 36
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCTN2 dynactin 2 (p50)
DEFB1 defensin, beta 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DENND2A DENN/MADD domain containing 2A
DLL4 delta-like 4 (Drosophila)
DMP1 dentin matrix acidic phosphoprotein 1
DMRTA2 DMRT-like family A2
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DPEP1 dipeptidase 1 (renal)
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator
ENG endoglin
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
ERICH4 glutamate-rich 4
ERICH6 glutamate-rich 6
ESAM endothelial cell adhesion molecule
ETV2 ets variant 2
EXOC3L2 exocyst complex component 3-like 2
F8A1 coagulation factor VIII-associated 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP5P3 fatty acid binding protein 5 pseudogene 3
FABP7 fatty acid binding protein 7, brain
FAM180B family with sequence similarity 180, member B
FAM181A family with sequence similarity 181, member A
FAM181A-AS1 FAM181A antisense RNA 1
FAM3B family with sequence similarity 3, member B
FAM3D family with sequence similarity 3, member D
FAM50B family with sequence similarity 50, member B
FAM58BP cyclin-related protein FAM58B
FAM86B2 family with sequence similarity 86, member B2
FBLN5 fibulin 5
FBN3 fibrillin 3
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FGF19 fibroblast growth factor 19
FGF22 fibroblast growth factor 22
FLT4 fms-related tyrosine kinase 4
FOXL2 forkhead box L2
FOXS1 forkhead box S1
FSCN1 fascin actin-bundling protein 1
FZD4 frizzled class receptor 4
G0S2 G0/G1 switch 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GDE1 glycerophosphodiester phosphodiesterase 1
GDF1 growth differentiation factor 1
GFI1B growth factor independent 1B transcription repressor
GGT3P gamma-glutamyltransferase 3 pseudogene
GLB1L3 galactosidase, beta 1-like 3
GLI1 GLI family zinc finger 1
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GPR1 G protein-coupled receptor 1
GPR4 G protein-coupled receptor 4
GPR55 G protein-coupled receptor 55
GPR68 G protein-coupled receptor 68
GPR89B G protein-coupled receptor 89B
GRAMD4 GRAM domain containing 4
GRAP GRB2-related adaptor protein
GRAPL GRB2-related adaptor protein-like
GSTM1 glutathione S-transferase mu 1
GSTM2P1 glutathione S-transferase mu 2 (muscle) pseudogene 1
GSTTP1 glutathione S-transferase theta pseudogene 1
GUCA1A guanylate cyclase activator 1A (retina)
HBZ hemoglobin, zeta
HCG9 HLA complex group 9 (non-protein coding)
HEBP2 heme binding protein 2
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HMGN2P46 high mobility group nucleosomal binding domain 2 pseudogene 46
HNF1B HNF1 homeobox B
HOXA10 homeobox A10
HOXA7 homeobox A7
HOXC10 homeobox C10
HOXC13 homeobox C13
HP haptoglobin
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
HSPG2 heparan sulfate proteoglycan 2
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IBSP integrin-binding sialoprotein
ICAM2 intercellular adhesion molecule 2
ICMT isoprenylcysteine carboxyl methyltransferase
IKBIP IKBKB interacting protein
INHBB inhibin, beta B
INSL6 insulin-like 6
IRX5 iroquois homeobox 5
ISM2 isthmin 2
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
ITM2C integral membrane protein 2C
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10
KCNG4 potassium channel, voltage gated modifier subfamily G, member 4
KCNIP1 Kv channel interacting protein 1
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCTD14 potassium channel tetramerization domain containing 14
KHDC1 KH homology domain containing 1
KIFC3 kinesin family member C3
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KLHL40 kelch-like family member 40
KLKP1 kallikrein pseudogene 1
KRT10 keratin 10, type I
KRTAP12-3 keratin associated protein 12-3
KRTAP4-11 keratin associated protein 4-11
KRTAP4-8 keratin associated protein 4-8
L1TD1 LINE-1 type transposase domain containing 1
LAMC3 laminin, gamma 3
LASP1 LIM and SH3 protein 1
LCN15 lipocalin 15
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LINC00152 long intergenic non-protein coding RNA 152
LINC00207 long intergenic non-protein coding RNA 207
LINC00589 long intergenic non-protein coding RNA 589
LINC01011 long intergenic non-protein coding RNA 1011
LINC01558 long intergenic non-protein coding RNA 1558
LIPM lipase, family member M
LOC100129935 lectin, galactoside-binding, soluble, 14 pseudogene
LOC284788 uncharacterized LOC284788
LOC391322 D-dopachrome tautomerase-like
LRRC36 leucine rich repeat containing 36
LRRC4B leucine rich repeat containing 4B
LRRC55 leucine rich repeat containing 55
LXN latexin
LY6G6D lymphocyte antigen 6 complex, locus G6D
MAGEA12 melanoma antigen family A12
MAGED1 melanoma antigen family D1
MEIS1 Meis homeobox 1
MEOX2 mesenchyme homeobox 2
MFSD2A major facilitator superfamily domain containing 2A
MFSD6L major facilitator superfamily domain containing 6-like
MGST2 microsomal glutathione S-transferase 2
MLN motilin
MMP2 matrix metallopeptidase 2
MMP25 matrix metallopeptidase 25
MMRN2 multimerin 2
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae)
MSLN mesothelin
MSRB1 methionine sulfoxide reductase B1
MT1M metallothionein 1M
MT4 metallothionein 4
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MYCT1 myc target 1
NCALD neurocalcin delta
NCF1C neutrophil cytosolic factor 1C pseudogene
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
NFAM1 NFAT activating protein with ITAM motif 1
NLRP6 NLR family, pyrin domain containing 6
NMNAT3 nicotinamide nucleotide adenylyltransferase 3
NMUR1 neuromedin U receptor 1
NODAL nodal growth differentiation factor
NOTCH4 notch 4
NOTO notochord homeobox
NOX4 NADPH oxidase 4
NQO2 NAD(P)H dehydrogenase, quinone 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRXN2 neurexin 2
OAZ3 ornithine decarboxylase antizyme 3
OR10J3 olfactory receptor, family 10, subfamily J, member 3
OR51E1 olfactory receptor, family 51, subfamily E, member 1
OR56A5 olfactory receptor, family 56, subfamily A, member 5
OTP orthopedia homeobox
P2RX6P purinergic receptor P2X, ligand gated ion channel, 6 pseudogene
PCDH12 protocadherin 12
PCDHA11 protocadherin alpha 11
PCDHB17P protocadherin beta 17 pseudogene
PCDHB4 protocadherin beta 4
PCDHB6 protocadherin beta 6
PCDHB7 protocadherin beta 7
PDGFB platelet-derived growth factor beta polypeptide
PFN3 profilin 3
PGM5 phosphoglucomutase 5
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PLEK2 pleckstrin 2
PLXDC1 plexin domain containing 1
PMEPA1 prostate transmembrane protein, androgen induced 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PNLIPRP2 pancreatic lipase-related protein 2
PNPLA4 patatin-like phospholipase domain containing 4
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POR P450 (cytochrome) oxidoreductase
PPIAL4C peptidylprolyl isomerase A (cyclophilin A)-like 4C
PPIAL4D peptidylprolyl isomerase A (cyclophilin A)-like 4D
PPIAL4G peptidylprolyl isomerase A (cyclophilin A)-like 4G
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C
PPP1R3G protein phosphatase 1, regulatory subunit 3G
PRKCDBP protein kinase C, delta binding protein
PRMT6 protein arginine methyltransferase 6
PRR5 proline rich 5 (renal)
PRR7 proline rich 7 (synaptic)
PRSS38 protease, serine, 38
PRSS54 protease, serine, 54
PTGFRN prostaglandin F2 receptor inhibitor
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PXDC1 PX domain containing 1
RAB34 RAB34, member RAS oncogene family
RADIL Ras association and DIL domains
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
RBAK RB-associated KRAB zinc finger
RBP1 retinol binding protein 1, cellular
RBP2 retinol binding protein 2, cellular
REC114 REC114 meiotic recombination protein
RETN resistin
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RHBG Rh family, B glycoprotein (gene/pseudogene)
RINL Ras and Rab interactor-like
RIT2 Ras-like without CAAX 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF216 ring finger protein 216
RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPL39L ribosomal protein L39-like
RTL1 retrotransposon-like 1
S100A16 S100 calcium binding protein A16
SAG S-antigen; retina and pineal gland (arrestin)
SCARF1 scavenger receptor class F, member 1
SDC3 syndecan 3
SELV selenoprotein V
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFTA1P surfactant associated 1, pseudogene
SH2B2 SH2B adaptor protein 2
SH2D3C SH2 domain containing 3C
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC29A4 solute carrier family 29 (equilibrative nucleoside transporter), member 4
SLC39A3 solute carrier family 39 (zinc transporter), member 3
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMAGP small cell adhesion glycoprotein
SMIM21 small integral membrane protein 21
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNAR-B2 small ILF3/NF90-associated RNA B2
SNORA16B small nucleolar RNA, H/ACA box 16B
SNORA18 small nucleolar RNA, H/ACA box 18
SNORA28 small nucleolar RNA, H/ACA box 28
SNORA36A small nucleolar RNA, H/ACA box 36A
SNORA55 small nucleolar RNA, H/ACA box 55
SNORA61 small nucleolar RNA, H/ACA box 61
SOCS1 suppressor of cytokine signaling 1
SOX18 SRY (sex determining region Y)-box 18
SOX30 SRY (sex determining region Y)-box 30
SP6 Sp6 transcription factor
SPANXB1 SPANX family, member B1
SPC24 SPC24, NDC80 kinetochore complex component
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPINK8 serine peptidase inhibitor, Kazal type 8 (putative)
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4
SRPRB signal recognition particle receptor, B subunit
SSX5 synovial sarcoma, X breakpoint 5
ST20-AS1 ST20 antisense RNA 1
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STEAP3 STEAP family member 3, metalloreductase
SUSD2 sushi domain containing 2
SYCE1L synaptonemal complex central element protein 1-like
SYNGR4 synaptogyrin 4
TAC1 tachykinin, precursor 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TAS1R1 taste receptor, type 1, member 1
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBX5 T-box 5
TCF15 transcription factor 15 (basic helix-loop-helix)
TGM6 transglutaminase 6
TLCD1 TLC domain containing 1
TM4SF18 transmembrane 4 L six family member 18
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM132A transmembrane protein 132A
TMEM159 transmembrane protein 159
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
TMEM200A transmembrane protein 200A
TMEM204 transmembrane protein 204
TMEM255B transmembrane protein 255B
TMEM51 transmembrane protein 51
TMEM61 transmembrane protein 61
TMEM82 transmembrane protein 82
TMSB4XP8 thymosin beta 4, X-linked pseudogene 8
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TREML3P triggering receptor expressed on myeloid cells-like 3, pseudogene
TRNP1 TMF1-regulated nuclear protein 1
TSPAN13 tetraspanin 13
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TTC36 tetratricopeptide repeat domain 36
TTC38 tetratricopeptide repeat domain 38
TTYH3 tweety family member 3
TWIST1 twist family bHLH transcription factor 1
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
UCK1 uridine-cytidine kinase 1
UFSP1 UFM1-specific peptidase 1 (non-functional)
USB1 U6 snRNA biogenesis 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VGLL2 vestigial-like family member 2
VPREB1 pre-B lymphocyte 1
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VWF von Willebrand factor
WFDC1 WAP four-disulfide core domain 1
WFDC2 WAP four-disulfide core domain 2
WIPI2 WD repeat domain, phosphoinositide interacting 2
WNT16 wingless-type MMTV integration site family, member 16
WNT7A wingless-type MMTV integration site family, member 7A
WSCD1 WSC domain containing 1
WT1 Wilms tumor 1
WT1-AS WT1 antisense RNA
XAGE1E X antigen family, member 1E
XKR8 XK, Kell blood group complex subunit-related family, member 8
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
XRCC6BP1 XRCC6 binding protein 1
YDJC YdjC homolog (bacterial)
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZIC1 Zic family member 1
ZNF503 zinc finger protein 503
ZNF880 zinc finger protein 880
ZP1 zona pellucida glycoprotein 1 (sperm receptor)
ZP3 zona pellucida glycoprotein 3 (sperm receptor)

low expression

Symbol Name
ATAD1 ATPase family, AAA domain containing 1
CHD8 chromodomain helicase DNA binding protein 8
GMPR2 guanosine monophosphate reductase 2
LARS leucyl-tRNA synthetase
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MRPS31 mitochondrial ribosomal protein S31
N4BP2L2 NEDD4 binding protein 2-like 2
NSUN3 NOP2/Sun domain family, member 3
R3HCC1L R3H domain and coiled-coil containing 1-like
R3HDM2 R3H domain containing 2
RNF170 ring finger protein 170
STRN3 striatin, calmodulin binding protein 3
TOX4 TOX high mobility group box family member 4
TRAM1L1 translocation associated membrane protein 1-like 1
TUBGCP3 tubulin, gamma complex associated protein 3
USP21 ubiquitin specific peptidase 21
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
WBP4 WW domain binding protein 4