Brain Lower Grade Glioma_LGG_TCGA-HT-7604-01A-11R-2090-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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405 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-HT-7604-01A-11R-2090-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ABI3BP ABI family, member 3 (NESH) binding protein
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
ADAM9 ADAM metallopeptidase domain 9
ADIPOR2 adiponectin receptor 2
AEBP2 AE binding protein 2
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
AHCYL2 adenosylhomocysteinase-like 2
AKAP3 A kinase (PRKA) anchor protein 3
AKAP9 A kinase (PRKA) anchor protein 9
AKR1C4 aldo-keto reductase family 1, member C4
ALCAM activated leukocyte cell adhesion molecule
ANAPC5 anaphase promoting complex subunit 5
ANKRD46 ankyrin repeat domain 46
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ASXL3 additional sex combs like transcriptional regulator 3
ATAD2 ATPase family, AAA domain containing 2
ATF7IP activating transcription factor 7 interacting protein
ATN1 atrophin 1
ATP11A ATPase, class VI, type 11A
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
AZIN1 antizyme inhibitor 1
BARD1 BRCA1 associated RING domain 1
BLID BH3-like motif containing, cell death inducer
BOP1 block of proliferation 1
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BTBD18 BTB (POZ) domain containing 18
C11ORF52 chromosome 11 open reading frame 52
C1ORF94 chromosome 1 open reading frame 94
C20ORF202 chromosome 20 open reading frame 202
C2CD5 C2 calcium-dependent domain containing 5
C2ORF78 chromosome 2 open reading frame 78
C8ORF33 chromosome 8 open reading frame 33
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCDC146 coiled-coil domain containing 146
CCDC15 coiled-coil domain containing 15
CCDC172 coiled-coil domain containing 172
CCDC178 coiled-coil domain containing 178
CCDC73 coiled-coil domain containing 73
CDC16 cell division cycle 16
CDCA3 cell division cycle associated 3
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHD4 chromodomain helicase DNA binding protein 4
CHRAC1 chromatin accessibility complex 1
CLUAP1 clusterin associated protein 1
CNTN3 contactin 3 (plasmacytoma associated)
COPG2 coatomer protein complex, subunit gamma 2
COPS7A COP9 signalosome subunit 7A
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CREBL2 cAMP responsive element binding protein-like 2
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
CTBP2 C-terminal binding protein 2
CUL4A cullin 4A
CXADRP3 coxsackie virus and adenovirus receptor pseudogene 3
CYC1 cytochrome c-1
DACH1 dachshund family transcription factor 1
DCAF13 DDB1 and CUL4 associated factor 13
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDHD2 DDHD domain containing 2
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DERA deoxyribose-phosphate aldolase (putative)
DERL1 derlin 1
DHRS4L1 dehydrogenase/reductase (SDR family) member 4 like 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLX5 distal-less homeobox 5
DLX6 distal-less homeobox 6
DPP10 dipeptidyl-peptidase 10 (non-functional)
DPY19L4 dpy-19-like 4 (C. elegans)
EBAG9 estrogen receptor binding site associated, antigen, 9
EBF1 early B-cell factor 1
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF4B eukaryotic translation initiation factor 4B
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERCC5 excision repair cross-complementation group 5
ERLIN2 ER lipid raft associated 2
ETNK1 ethanolamine kinase 1
EXOC4 exocyst complex component 4
EYS eyes shut homolog (Drosophila)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
FAM133A family with sequence similarity 133, member A
FAM182A family with sequence similarity 182, member A
FAM49B family with sequence similarity 49, member B
FAM84B family with sequence similarity 84, member B
FBXL14 F-box and leucine-rich repeat protein 14
FGF11 fibroblast growth factor 11
FKBP4 FK506 binding protein 4, 59kDa
FNTA farnesyltransferase, CAAX box, alpha
FOXJ2 forkhead box J2
FOXP2 forkhead box P2
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9
GGTA1P glycoprotein, alpha-galactosyltransferase 1 pseudogene
GK2 glycerol kinase 2
GLB1L2 galactosidase, beta 1-like 2
GOLGA7 golgin A7
GPR153 G protein-coupled receptor 153
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRK7 G protein-coupled receptor kinase 7
GRTP1 growth hormone regulated TBC protein 1
GSPT1 G1 to S phase transition 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HAS2-AS1 HAS2 antisense RNA 1
HCFC2 host cell factor C2
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HLTF helicase-like transcription factor
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOOK3 hook microtubule-tethering protein 3
HP1BP3 heterochromatin protein 1, binding protein 3
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL37 interleukin 37
ING4 inhibitor of growth family, member 4
INTS8 integrator complex subunit 8
IPO11 importin 11
IPO5 importin 5
IPO7 importin 7
IPW imprinted in Prader-Willi syndrome (non-protein coding)
ITFG2 integrin alpha FG-GAP repeat containing 2
JRK Jrk homolog (mouse)
KAT6A K(lysine) acetyltransferase 6A
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KDM5A lysine (K)-specific demethylase 5A
KIAA0196 KIAA0196
KIAA1033 KIAA1033
KIAA1429 KIAA1429
KIAA1467 KIAA1467
KIAA1549 KIAA1549
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KLHL13 kelch-like family member 13
KLHL31 kelch-like family member 31
KLHL42 kelch-like family member 42
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRC3 killer cell lectin-like receptor subfamily C, member 3
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2E lysine (K)-specific methyltransferase 2E
LAMP1 lysosomal-associated membrane protein 1
LAPTM4B lysosomal protein transmembrane 4 beta
LDHB lactate dehydrogenase B
LHX3 LIM homeobox 3
LOC374443 C-type lectin domain family 2, member D pseudogene
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPL lipoprotein lipase
LRP12 low density lipoprotein receptor-related protein 12
LRRC14 leucine rich repeat containing 14
LSM1 LSM1, U6 small nuclear RNA associated
LUZP2 leucine zipper protein 2
LYRM5 LYR motif containing 5
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAGOHB mago-nashi homolog B (Drosophila)
MED21 mediator complex subunit 21
MED22 mediator complex subunit 22
METTL12 methyltransferase like 12
MGAT4C MGAT4 family, member C
MKI67 marker of proliferation Ki-67
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MKX mohawk homeobox
MLF2 myeloid leukemia factor 2
MRPL51 mitochondrial ribosomal protein L51
MRPS35 mitochondrial ribosomal protein S35
MSH3 mutS homolog 3
MTDH metadherin
MYO16 myosin XVI
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NALCN sodium leak channel, non selective
NBPF1 neuroblastoma breakpoint family, member 1
NBPF15 neuroblastoma breakpoint family, member 15
NCAPD2 non-SMC condensin I complex, subunit D2
NCOR2 nuclear receptor corepressor 2
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NLGN4X neuroligin 4, X-linked
NME1-NME2 NME1-NME2 readthrough
NOP2 NOP2 nucleolar protein
NOTCH2NL notch 2 N-terminal like
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OR1A2 olfactory receptor, family 1, subfamily A, member 2
OR4M1 olfactory receptor, family 4, subfamily M, member 1
OR4N3P olfactory receptor, family 4, subfamily N, member 3 pseudogene
OSGIN2 oxidative stress induced growth inhibitor family member 2
PABPC1 poly(A) binding protein, cytoplasmic 1
PARP11 poly (ADP-ribose) polymerase family, member 11
PBX1 pre-B-cell leukemia homeobox 1
PCDHB17P protocadherin beta 17 pseudogene
PCID2 PCI domain containing 2
PDZRN4 PDZ domain containing ring finger 4
PEX5 peroxisomal biogenesis factor 5
PHB2 prohibitin 2
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF20L1 PHD finger protein 20-like 1
PIANP PILR alpha associated neural protein
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLEC plectin
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHA5 pleckstrin homology domain containing, family A member 5
POLB polymerase (DNA directed), beta
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POMK protein-O-mannose kinase
POT1 protection of telomeres 1
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRAMEF4 PRAME family member 4
PRH1 proline-rich protein HaeIII subfamily 1
PRKG2 protein kinase, cGMP-dependent, type II
PROSC proline synthetase co-transcribed homolog (bacterial)
PRRX1 paired related homeobox 1
PRTFDC1 phosphoribosyl transferase domain containing 1
PSG3 pregnancy specific beta-1-glycoprotein 3
PTDSS1 phosphatidylserine synthase 1
PTGDR prostaglandin D2 receptor (DP)
PTK2 protein tyrosine kinase 2
PUF60 poly-U binding splicing factor 60KDa
PUS7 pseudouridylate synthase 7 (putative)
PYCRL pyrroline-5-carboxylate reductase-like
RAB23 RAB23, member RAS oncogene family
RAD21 RAD21 homolog (S. pombe)
RAD52 RAD52 homolog (S. cerevisiae)
RASA3 RAS p21 protein activator 3
RDX radixin
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFTN2 raftlin family member 2
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RICTOR RPTOR independent companion of MTOR, complex 2
RIMKLB ribosomal modification protein rimK-like family member B
RIPK4 receptor-interacting serine-threonine kinase 4
RIPPLY1 ripply transcriptional repressor 1
RNF139 ring finger protein 139
RNF170 ring finger protein 170
RNF182 ring finger protein 182
RPL13P5 ribosomal protein L13 pseudogene 5
RPL30 ribosomal protein L30
RPL7L1 ribosomal protein L7-like 1
RPS26P11 ribosomal protein S26 pseudogene 11
SDHAF3 succinate dehydrogenase complex assembly factor 3
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SERBP1 SERPINE1 mRNA binding protein 1
SERHL serine hydrolase-like (pseudogene)
SIDT1 SID1 transmembrane family, member 1
SIX1 SIX homeobox 1
SIX4 SIX homeobox 4
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional)
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLITRK3 SLIT and NTRK-like family, member 3
SMAD1 SMAD family member 1
SMIM19 small integral membrane protein 19
SND1 staphylococcal nuclease and tudor domain containing 1
SNORA14B small nucleolar RNA, H/ACA box 14B
SOX5 SRY (sex determining region Y)-box 5
SPINK1 serine peptidase inhibitor, Kazal type 1
SSR1 signal sequence receptor, alpha
ST7L suppression of tumorigenicity 7 like
STAR steroidogenic acute regulatory protein
STOX1 storkhead box 1
STRAP serine/threonine kinase receptor associated protein
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
SYTL4 synaptotagmin-like 4
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TAGAP T-cell activation RhoGTPase activating protein
TAPT1 transmembrane anterior posterior transformation 1
TAS2R10 taste receptor, type 2, member 10
TAS2R14 taste receptor, type 2, member 14
TAS2R20 taste receptor, type 2, member 20
TAS2R9 taste receptor, type 2, member 9
TATDN1 TatD DNase domain containing 1
TCP11 t-complex 11, testis-specific
TECRL trans-2,3-enoyl-CoA reductase-like
TFDP1 transcription factor Dp-1
THAP1 THAP domain containing, apoptosis associated protein 1
THAP5 THAP domain containing 5
THEM6 thioesterase superfamily member 6
TIGD2 tigger transposable element derived 2
TIGD5 tigger transposable element derived 5
TIGD6 tigger transposable element derived 6
TM2D2 TM2 domain containing 2
TM7SF3 transmembrane 7 superfamily member 3
TMCO3 transmembrane and coiled-coil domains 3
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM106B transmembrane protein 106B
TMEM236 transmembrane protein 236
TMEM65 transmembrane protein 65
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNPO3 transportin 3
TOP1MT topoisomerase (DNA) I, mitochondrial
TPI1 triosephosphate isomerase 1
TPP2 tripeptidyl peptidase II
TRAPPC9 trafficking protein particle complex 9
TRDN triadin
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TRPS1 trichorhinophalangeal syndrome I
TSG1 tumor suppressor TSG1
TSHR thyroid stimulating hormone receptor
TUBGCP3 tubulin, gamma complex associated protein 3
UBA2 ubiquitin-like modifier activating enzyme 2
UBE3A ubiquitin protein ligase E3A
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UHRF1BP1L UHRF1 binding protein 1-like
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
UQCRB ubiquinol-cytochrome c reductase binding protein
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UTP23 UTP23, small subunit (SSU) processome component, homolog (yeast)
VDAC3 voltage-dependent anion channel 3
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WBP11 WW domain binding protein 11
WDYHV1 WDYHV motif containing 1
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WNK1 WNK lysine deficient protein kinase 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
ZBED1 zinc finger, BED-type containing 1
ZBTB1 zinc finger and BTB domain containing 1
ZBTB2 zinc finger and BTB domain containing 2
ZBTB32 zinc finger and BTB domain containing 32
ZBTB6 zinc finger and BTB domain containing 6
ZC3H12C zinc finger CCCH-type containing 12C
ZFHX4 zinc finger homeobox 4
ZFP41 ZFP41 zinc finger protein
ZFPM2 zinc finger protein, FOG family member 2
ZHX1 zinc fingers and homeoboxes 1
ZHX2 zinc fingers and homeoboxes 2
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF114 zinc finger protein 114
ZNF146 zinc finger protein 146
ZNF16 zinc finger protein 16
ZNF250 zinc finger protein 250
ZNF251 zinc finger protein 251
ZNF252P zinc finger protein 252, pseudogene
ZNF34 zinc finger protein 34
ZNF384 zinc finger protein 384
ZNF544 zinc finger protein 544
ZNF559 zinc finger protein 559
ZNF611 zinc finger protein 611
ZNF623 zinc finger protein 623
ZNF664 zinc finger protein 664
ZNF696 zinc finger protein 696
ZNF7 zinc finger protein 7
ZNF707 zinc finger protein 707
ZNF770 zinc finger protein 770
ZNF772 zinc finger protein 772
ZNF788 zinc finger family member 788
ZNF804A zinc finger protein 804A
ZNF813 zinc finger protein 813

low expression

Symbol Name
ACOT2 acyl-CoA thioesterase 2
ANAPC7 anaphase promoting complex subunit 7
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
ATXN2 ataxin 2
BBS5 Bardet-Biedl syndrome 5
BRAP BRCA1 associated protein
C12ORF76 chromosome 12 open reading frame 76
C8ORF44 chromosome 8 open reading frame 44
COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FBXO45 F-box protein 45
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
KIAA0226 KIAA0226
LOC728613 programmed cell death 6 pseudogene
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
NOL7 nucleolar protein 7, 27kDa
PIGX phosphatidylinositol glycan anchor biosynthesis, class X
PLBD2 phospholipase B domain containing 2
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PRDM4 PR domain containing 4
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PWP1 PWP1 homolog (S. cerevisiae)
RAB35 RAB35, member RAS oncogene family
RBM19 RNA binding motif protein 19
RITA1 RBPJ interacting and tubulin associated 1
RNF10 ring finger protein 10
SART3 squamous cell carcinoma antigen recognized by T cells 3
SDHAF4 succinate dehydrogenase complex assembly factor 4
SENP5 SUMO1/sentrin specific peptidase 5
SIRT5 sirtuin 5
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
SPPL3 signal peptide peptidase like 3
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
TMEM14B transmembrane protein 14B
TNPO2 transportin 2
TRAFD1 TRAF-type zinc finger domain containing 1
UBE3B ubiquitin protein ligase E3B
UBL4A ubiquitin-like 4A
USP30 ubiquitin specific peptidase 30
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
WDR53 WD repeat domain 53
WSB2 WD repeat and SOCS box containing 2
ZNF490 zinc finger protein 490
ZNF512 zinc finger protein 512
ZSCAN12 zinc finger and SCAN domain containing 12