Brain Lower Grade Glioma_LGG_TCGA-HW-7490-01A-11R-2027-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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301 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-HW-7490-01A-11R-2027-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AARS alanyl-tRNA synthetase
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACAT1 acetyl-CoA acetyltransferase 1
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
ADAR adenosine deaminase, RNA-specific
ADGRF5 adhesion G protein-coupled receptor F5
AIM2 absent in melanoma 2
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AKAP1 A kinase (PRKA) anchor protein 1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
APOLD1 apolipoprotein L domain containing 1
AQP7P1 aquaporin 7 pseudogene 1
AQP7P3 aquaporin 7 pseudogene 3
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASB17 ankyrin repeat and SOCS box containing 17
ASPH aspartate beta-hydroxylase
AZI2 5-azacytidine induced 2
B2M beta-2-microglobulin
BBS1 Bardet-Biedl syndrome 1
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BIRC2 baculoviral IAP repeat containing 2
BTF3L4 basic transcription factor 3-like 4
C11ORF1 chromosome 11 open reading frame 1
C11ORF52 chromosome 11 open reading frame 52
C11ORF57 chromosome 11 open reading frame 57
C17ORF98 chromosome 17 open reading frame 98
C1ORF100 chromosome 1 open reading frame 100
C1ORF43 chromosome 1 open reading frame 43
C1QTNF7 C1q and tumor necrosis factor related protein 7
C20ORF202 chromosome 20 open reading frame 202
CARS cysteinyl-tRNA synthetase
CASP12 caspase 12 (gene/pseudogene)
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC86 coiled-coil domain containing 86
CCL19 chemokine (C-C motif) ligand 19
CCPG1 cell cycle progression 1
CHPT1 choline phosphotransferase 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLEC14A C-type lectin domain family 14, member A
CLEC1A C-type lectin domain family 1, member A
CLEC3B C-type lectin domain family 3, member B
CLIC2 chloride intracellular channel 2
CNBP CCHC-type zinc finger, nucleic acid binding protein
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae)
COLCA1 colorectal cancer associated 1
COLCA2 colorectal cancer associated 2
CRBN cereblon
CRY2 cryptochrome circadian clock 2
CSRP2 cysteine and glycine-rich protein 2
CT45A1 cancer/testis antigen family 45, member A1
CT45A2 cancer/testis antigen family 45, member A2
CT45A3 cancer/testis antigen family 45, member A3
CTSG cathepsin G
CWC15 CWC15 spliceosome-associated protein
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DHRS7C dehydrogenase/reductase (SDR family) member 7C
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DLAT dihydrolipoamide S-acetyltransferase
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DPF2 D4, zinc and double PHD fingers family 2
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EI24 etoposide induced 2.4
EIF3J eukaryotic translation initiation factor 3, subunit J
ELOVL7 ELOVL fatty acid elongase 7
ENOPH1 enolase-phosphatase 1
EPGN epithelial mitogen
FAM124B family with sequence similarity 124B
FAM27C family with sequence similarity 27, member C
FBXO6 F-box protein 6
FIBIN fin bud initiation factor homolog (zebrafish)
FLJ41941 uncharacterized LOC100192420
FTH1 ferritin, heavy polypeptide 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GIMAP5 GTPase, IMAP family member 5
GLO1 glyoxalase I
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNPDA2 glucosamine-6-phosphate deaminase 2
GPR151 G protein-coupled receptor 151
GPX3 glutathione peroxidase 3
GSTTP1 glutathione S-transferase theta pseudogene 1
HADH hydroxyacyl-CoA dehydrogenase
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HUS1B HUS1 checkpoint homolog b (S. pombe)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFITM1 interferon induced transmembrane protein 1
IGFBP1 insulin-like growth factor binding protein 1
INTS5 integrator complex subunit 5
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
JADE1 jade family PHD finger 1
KARS lysyl-tRNA synthetase
KAT5 K(lysine) acetyltransferase 5
KCMF1 potassium channel modulatory factor 1
KDSR 3-ketodihydrosphingosine reductase
KLF9 Kruppel-like factor 9
KRTAP4-9 keratin associated protein 4-9
L2HGDH L-2-hydroxyglutarate dehydrogenase
LACTB2 lactamase, beta 2
LARS leucyl-tRNA synthetase
LENEP lens epithelial protein
LEPR leptin receptor
LIMCH1 LIM and calponin homology domains 1
LIN52 lin-52 DREAM MuvB core complex component
LYPD5 LY6/PLAUR domain containing 5
LYRM5 LYR motif containing 5
MANEAL mannosidase, endo-alpha-like
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MBIP MAP3K12 binding inhibitory protein 1
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
METTL5 methyltransferase like 5
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type
MRPL1 mitochondrial ribosomal protein L1
MRPL49 mitochondrial ribosomal protein L49
MRPS18B mitochondrial ribosomal protein S18B
MRPS18C mitochondrial ribosomal protein S18C
MRPS22 mitochondrial ribosomal protein S22
MT4 metallothionein 4
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTM1 myotubularin 1
MTO1 mitochondrial tRNA translation optimization 1
MYCT1 myc target 1
NARS asparaginyl-tRNA synthetase
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative)
NLRX1 NLR family member X1
NMB neuromedin B
NPAT nuclear protein, ataxia-telangiectasia locus
NPC1L1 NPC1-like 1
NPHP3-AS1 NPHP3 antisense RNA 1
NPVF neuropeptide VF precursor
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OPN5 opsin 5
OR4D2 olfactory receptor, family 4, subfamily D, member 2
OR52I1 olfactory receptor, family 52, subfamily I, member 1
ORC3 origin recognition complex, subunit 3
OSBPL11 oxysterol binding protein-like 11
OSBPL9 oxysterol binding protein-like 9
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PANX3 pannexin 3
PAQR3 progestin and adipoQ receptor family member III
PARP9 poly (ADP-ribose) polymerase family, member 9
PCCA propionyl CoA carboxylase, alpha polypeptide
PCTP phosphatidylcholine transfer protein
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDE8B phosphodiesterase 8B
PDHX pyruvate dehydrogenase complex, component X
PEAK1 pseudopodium-enriched atypical kinase 1
PEX13 peroxisomal biogenesis factor 13
PEX19 peroxisomal biogenesis factor 19
PHOX2A paired-like homeobox 2a
PLA1A phospholipase A1 member A
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
POM121L2 POM121 transmembrane nucleoporin-like 2
POU1F1 POU class 1 homeobox 1
POU2F3 POU class 2 homeobox 3
PPA2 pyrophosphatase (inorganic) 2
PPARD peroxisome proliferator-activated receptor delta
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRDX3 peroxiredoxin 3
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PRMT5 protein arginine methyltransferase 5
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
RAB6C RAB6C, member RAS oncogene family
RABGGTB Rab geranylgeranyltransferase, beta subunit
RAG2 recombination activating gene 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RGAG1 retrotransposon gag domain containing 1
RNF182 ring finger protein 182
RPL23P8 ribosomal protein L23 pseudogene 8
RPS4Y2 ribosomal protein S4, Y-linked 2
RRAGD Ras-related GTP binding D
RSAD1 radical S-adenosyl methionine domain containing 1
RTP4 receptor (chemosensory) transporter protein 4
RUNDC3B RUN domain containing 3B
SARS seryl-tRNA synthetase
SCAND2P SCAN domain containing 2 pseudogene
SCARNA9L small Cajal body-specific RNA 9-like
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SDPR serum deprivation response
SELK selenoprotein K
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEPT2 septin 2
SF3B2 splicing factor 3b, subunit 2, 145kDa
SFTPA2 surfactant protein A2
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
SNX15 sorting nexin 15
SNX19 sorting nexin 19
SNX31 sorting nexin 31
SNX5 sorting nexin 5
SORCS1 sortilin-related VPS10 domain containing receptor 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SPIRE1 spire-type actin nucleation factor 1
SQSTM1 sequestosome 1
SSX6 synovial sarcoma, X breakpoint 6 (pseudogene)
STAT1 signal transducer and activator of transcription 1, 91kDa
STIP1 stress-induced phosphoprotein 1
STOX1 storkhead box 1
STX5 syntaxin 5
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SV2C synaptic vesicle glycoprotein 2C
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TARP TCR gamma alternate reading frame protein
TAS1R2 taste receptor, type 1, member 2
TBC1D21 TBC1 domain family, member 21
TCEA1 transcription elongation factor A (SII), 1
TCP11 t-complex 11, testis-specific
TENM4 teneurin transmembrane protein 4
TEX13B testis expressed 13B
TFDP3 transcription factor Dp family, member 3
TGM2 transglutaminase 2
TGM6 transglutaminase 6
TIGD2 tigger transposable element derived 2
TIGD7 tigger transposable element derived 7
TMEM123 transmembrane protein 123
TMEM126A transmembrane protein 126A
TMEM126B transmembrane protein 126B
TMEM135 transmembrane protein 135
TMEM164 transmembrane protein 164
TMEM179B transmembrane protein 179B
TMEM223 transmembrane protein 223
TMLHE trimethyllysine hydroxylase, epsilon
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOB2 transducer of ERBB2, 2
TREML4 triggering receptor expressed on myeloid cells-like 4
TRIM64 tripartite motif containing 64
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRPT1 tRNA phosphotransferase 1
TSC22D1 TSC22 domain family, member 1
TUBAL3 tubulin, alpha-like 3
UBA2 ubiquitin-like modifier activating enzyme 2
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
ULBP1 UL16 binding protein 1
UPP2 uridine phosphorylase 2
USP28 ubiquitin specific peptidase 28
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
UTRN utrophin
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
XIRP2 xin actin binding repeat containing 2
XPOT exportin, tRNA
YARS tyrosyl-tRNA synthetase
YIPF7 Yip1 domain family, member 7
ZBTB7C zinc finger and BTB domain containing 7C
ZFAT zinc finger and AT hook domain containing
ZNF181 zinc finger protein 181
ZNF330 zinc finger protein 330
ZNF610 zinc finger protein 610
ZNF684 zinc finger protein 684
ZNF766 zinc finger protein 766
ZNF826P zinc finger protein 826, pseudogene
ZPR1 ZPR1 zinc finger
ZW10 zw10 kinetochore protein

low expression

Symbol Name
LGTN ligatin
MCM3AP minichromosome maintenance complex component 3 associated protein
PCNT pericentrin
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
SCAF4 SR-related CTD-associated factor 4
THUMPD2 THUMP domain containing 2
TRAPPC10 trafficking protein particle complex 10
USP16 ubiquitin specific peptidase 16