Brain Lower Grade Glioma_LGG_TCGA-KT-A74X-01A-11R-A32Q-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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339 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-KT-A74X-01A-11R-A32Q-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD5 abhydrolase domain containing 5
ACAT2 acetyl-CoA acetyltransferase 2
ACOT2 acyl-CoA thioesterase 2
ACP5 acid phosphatase 5, tartrate resistant
ACTR3BP2 ACTR3B pseudogene 2
ADA adenosine deaminase
ADAM21 ADAM metallopeptidase domain 21
ADCK1 aarF domain containing kinase 1
ADGRA1 adhesion G protein-coupled receptor A1
ADGRG3 adhesion G protein-coupled receptor G3
AFAP1L2 actin filament associated protein 1-like 2
AHSG alpha-2-HS-glycoprotein
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
AMT aminomethyltransferase
AMTN amelotin
AMZ1 archaelysin family metallopeptidase 1
ANXA10 annexin A10
ARL14 ADP-ribosylation factor-like 14
ARL4A ADP-ribosylation factor-like 4A
ASCL3 achaete-scute family bHLH transcription factor 3
ASIC1 acid sensing (proton gated) ion channel 1
ATCAY ataxia, cerebellar, Cayman type
ATG3 autophagy related 3
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
BAALC brain and acute leukemia, cytoplasmic
BAALC-AS2 BAALC antisense RNA 2
BARHL1 BarH-like homeobox 1
BCL6B B-cell CLL/lymphoma 6, member B
BEND4 BEN domain containing 4
BLCAP bladder cancer associated protein
BLMH bleomycin hydrolase
BMPER BMP binding endothelial regulator
BTBD17 BTB (POZ) domain containing 17
C10ORF99 chromosome 10 open reading frame 99
C11ORF71 chromosome 11 open reading frame 71
C15ORF59 chromosome 15 open reading frame 59
C18ORF32 chromosome 18 open reading frame 32
C1ORF100 chromosome 1 open reading frame 100
C1ORF106 chromosome 1 open reading frame 106
C1QL2 complement component 1, q subcomponent-like 2
C20ORF196 chromosome 20 open reading frame 196
C22ORF46 chromosome 22 open reading frame 46
C2ORF27A chromosome 2 open reading frame 27A
C2ORF72 chromosome 2 open reading frame 72
CA10 carbonic anhydrase X
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASP14 caspase 14, apoptosis-related cysteine peptidase
CBLN1 cerebellin 1 precursor
CD81 CD81 molecule
CD82 CD82 molecule
CDA cytidine deaminase
CDC42SE1 CDC42 small effector 1
CDHR1 cadherin-related family member 1
CEL carboxyl ester lipase
CENPV centromere protein V
CETP cholesteryl ester transfer protein, plasma
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CIDECP cell death-inducing DFFA-like effector c pseudogene
CLCA2 chloride channel accessory 2
COQ3 coenzyme Q3 methyltransferase
CORO7 coronin 7
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CRCT1 cysteine-rich C-terminal 1
CREB3L1 cAMP responsive element binding protein 3-like 1
CSH2 chorionic somatomammotropin hormone 2
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CST5 cystatin D
CSTA cystatin A (stefin A)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DEFA6 defensin, alpha 6, Paneth cell-specific
DEFB103B defensin, beta 103B
DEFB131 defensin, beta 131
DGCR6 DiGeorge syndrome critical region gene 6
DHCR7 7-dehydrocholesterol reductase
DLK2 delta-like 2 homolog (Drosophila)
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOK4 docking protein 4
DSG3 desmoglein 3
EBP emopamil binding protein (sterol isomerase)
EFHB EF-hand domain family, member B
EI24 etoposide induced 2.4
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
EPN2 epsin 2
EVI5L ecotropic viral integration site 5-like
EXOC3L1 exocyst complex component 3-like 1
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FAM155B family with sequence similarity 155, member B
FAM192A family with sequence similarity 192, member A
FAM219A family with sequence similarity 219, member A
FAM25A family with sequence similarity 25, member A
FAM83A family with sequence similarity 83, member A
FBLL1 fibrillarin-like 1
FBXW4 F-box and WD repeat domain containing 4
FDPS farnesyl diphosphate synthase
FGFBP1 fibroblast growth factor binding protein 1
FGFBP3 fibroblast growth factor binding protein 3
FMR1NB fragile X mental retardation 1 neighbor
FOXF2 forkhead box F2
GAL3ST1 galactose-3-O-sulfotransferase 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GDF11 growth differentiation factor 11
GDF9 growth differentiation factor 9
GGTLC1 gamma-glutamyltransferase light chain 1
GPC2 glypican 2
GPR17 G protein-coupled receptor 17
GPX2 glutathione peroxidase 2
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GUCD1 guanylyl cyclase domain containing 1
HDAC8 histone deacetylase 8
HDDC2 HD domain containing 2
HMGB3 high mobility group box 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGN5 high mobility group nucleosome binding domain 5
HMP19 HMP19 protein
HR hair growth associated
IGDCC3 immunoglobulin superfamily, DCC subclass, member 3
INSM2 insulinoma-associated 2
ITPK1 inositol-tetrakisphosphate 1-kinase
IVL involucrin
IWS1 IWS1 homolog (S. cerevisiae)
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNIP1 Kv channel interacting protein 1
KCNIP3 Kv channel interacting protein 3, calsenilin
KCNK2 potassium channel, two pore domain subfamily K, member 2
KIAA1644 KIAA1644
KIF26B kinesin family member 26B
KLHL35 kelch-like family member 35
KLK10 kallikrein-related peptidase 10
KLK12 kallikrein-related peptidase 12
KLK8 kallikrein-related peptidase 8
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KRT1 keratin 1, type II
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT6C keratin 6C, type II
KRTDAP keratinocyte differentiation-associated protein
LAD1 ladinin 1
LAMC2 laminin, gamma 2
LCE1A late cornified envelope 1A
LCE3D late cornified envelope 3D
LCE3E late cornified envelope 3E
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LGALS7 lectin, galactoside-binding, soluble, 7
LHX5 LIM homeobox 5
LIMS2 LIM and senescent cell antigen-like domains 2
LINC00472 long intergenic non-protein coding RNA 472
LINC00597 long intergenic non-protein coding RNA 597
LINGO1 leucine rich repeat and Ig domain containing 1
LOC100272217 uncharacterized LOC100272217
LOC145783 uncharacterized LOC145783
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene
LRRC16B leucine rich repeat containing 16B
LRRC75B leucine rich repeat containing 75B
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LY6D lymphocyte antigen 6 complex, locus D
MAGED4 melanoma antigen family D4
MARCH4 membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
MATN3 matrilin 3
MB myoglobin
MDS2 myelodysplastic syndrome 2 translocation associated
MEGF11 multiple EGF-like-domains 11
METTL21A methyltransferase like 21A
MPHOSPH6 M-phase phosphoprotein 6
MPV17L2 MPV17 mitochondrial membrane protein-like 2
MRFAP1L1 Morf4 family associated protein 1-like 1
MT3 metallothionein 3
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
NAAA N-acylethanolamine acid amidase
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
NEU4 sialidase 4
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
NKG7 natural killer cell granule protein 7
NLGN3 neuroligin 3
NMRK2 nicotinamide riboside kinase 2
NMUR2 neuromedin U receptor 2
NPR2 natriuretic peptide receptor 2
NR0B1 nuclear receptor subfamily 0, group B, member 1
NRADDP neurotrophin receptor associated death domain, pseudogene
NRXN2 neurexin 2
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUP210 nucleoporin 210kDa
NUP35 nucleoporin 35kDa
NUTM2D NUT family member 2D
NXN nucleoredoxin
NXPH1 neurexophilin 1
OMG oligodendrocyte myelin glycoprotein
OR11G2 olfactory receptor, family 11, subfamily G, member 2
OR2G3 olfactory receptor, family 2, subfamily G, member 3
OXSM 3-oxoacyl-ACP synthase, mitochondrial
PANK1 pantothenate kinase 1
PBDC1 polysaccharide biosynthesis domain containing 1
PBLD phenazine biosynthesis-like protein domain containing
PCBP4 poly(rC) binding protein 4
PCDHA1 protocadherin alpha 1
PCDHA11 protocadherin alpha 11
PCDHGB4 protocadherin gamma subfamily B, 4
PEA15 phosphoprotein enriched in astrocytes 15
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PGLYRP4 peptidoglycan recognition protein 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PI3 peptidase inhibitor 3, skin-derived
PISRT1 polled intersex syndrome regulated transcript 1 (non-protein coding RNA)
PLA2G4E phospholipase A2, group IVE
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNPLA3 patatin-like phospholipase domain containing 3
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
PORCN porcupine homolog (Drosophila)
PRAMEF16 PRAME family member 16
PRAMEF8 PRAME family member 8
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PTMA prothymosin, alpha
PTRH2 peptidyl-tRNA hydrolase 2
PURG purine-rich element binding protein G
RAB31 RAB31, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RAET1E retinoic acid early transcript 1E
RASGEF1C RasGEF domain family, member 1C
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RCOR2 REST corepressor 2
RGMB repulsive guidance molecule family member b
RND2 Rho family GTPase 2
RNFT2 ring finger protein, transmembrane 2
RPP40 ribonuclease P/MRP 40kDa subunit
RPTN repetin
RPUSD3 RNA pseudouridylate synthase domain containing 3
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A14 S100 calcium binding protein A14
S100A7 S100 calcium binding protein A7
S100A7A S100 calcium binding protein A7A
SBSN suprabasin
SCARNA9L small Cajal body-specific RNA 9-like
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCP2D1 SCP2 sterol-binding domain containing 1
SEPT8 septin 8
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SEZ6 seizure related 6 homolog (mouse)
SFN stratifin
SIGLEC15 sialic acid binding Ig-like lectin 15
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMOC1 SPARC related modular calcium binding 1
SNX1 sorting nexin 1
SNX22 sorting nexin 22
SPANXA2 SPANX family, member A2
SPANXD SPANX family, member D
SPIN3 spindlin family, member 3
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2A small proline-rich protein 2A
SPRR2B small proline-rich protein 2B
SPRR2D small proline-rich protein 2D
SPRR2E small proline-rich protein 2E
SPRR2G small proline-rich protein 2G
SPRR4 small proline-rich protein 4
SPRY3 sprouty homolog 3 (Drosophila)
SPRYD4 SPRY domain containing 4
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4
SRP19 signal recognition particle 19kDa
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD6 StAR-related lipid transfer (START) domain containing 6
SUCLG1 succinate-CoA ligase, alpha subunit
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TBC1D21 TBC1 domain family, member 21
TCEAL3 transcription elongation factor A (SII)-like 3
TCEAL4 transcription elongation factor A (SII)-like 4
TCEAL5 transcription elongation factor A (SII)-like 5
THTPA thiamine triphosphatase
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast)
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
TM4SF19 transmembrane 4 L six family member 19
TMEM121 transmembrane protein 121
TMEM169 transmembrane protein 169
TMEM251 transmembrane protein 251
TMEM253 transmembrane protein 253
TMEM45B transmembrane protein 45B
TMEM97 transmembrane protein 97
TMSB4Y thymosin beta 4, Y-linked
TNP2 transition protein 2 (during histone to protamine replacement)
TNS4 tensin 4
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
TRAF4 TNF receptor-associated factor 4
TRMT61B tRNA methyltransferase 61B
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1
TTTY18 testis-specific transcript, Y-linked 18 (non-protein coding)
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
USB1 U6 snRNA biogenesis 1
VASH1 vasohibin 1
VLDLR very low density lipoprotein receptor
VPREB1 pre-B lymphocyte 1
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae)
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
WDR89 WD repeat domain 89
WFDC12 WAP four-disulfide core domain 12
WFDC5 WAP four-disulfide core domain 5
WNT7B wingless-type MMTV integration site family, member 7B
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC22 zinc finger, DHHC-type containing 22
ZNF219 zinc finger protein 219
ZNF32 zinc finger protein 32
ZNF385A zinc finger protein 385A

low expression

Symbol Name
CDC16 cell division cycle 16
COPS4 COP9 signalosome subunit 4
CUL4A cullin 4A
FBXL3 F-box and leucine-rich repeat protein 3
HELQ helicase, POLQ-like
IPO5 importin 5
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
MED4 mediator complex subunit 4
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
PAQR7 progestin and adipoQ receptor family member VII
PCID2 PCI domain containing 2
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
SEC24B SEC24 family member B
UBE2D3 ubiquitin-conjugating enzyme E2D 3
WBP4 WW domain binding protein 4
ZNF808 zinc finger protein 808