Brain Lower Grade Glioma_LGG_TCGA-P5-A5EW-01A-11R-A27Q-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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235 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-P5-A5EW-01A-11R-A27Q-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADCY2 adenylate cyclase 2 (brain)
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8 (brain)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
AHCYL1 adenosylhomocysteinase-like 1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AMOT angiomotin
AMOTL1 angiomotin like 1
ANGPTL3 angiopoietin-like 3
ARHGAP35 Rho GTPase activating protein 35
ARHGAP5 Rho GTPase activating protein 5
ARID1A AT rich interactive domain 1A (SWI-like)
ASB3 ankyrin repeat and SOCS box containing 3
AUTS2 autism susceptibility candidate 2
AXIN2 axin 2
BMP15 bone morphogenetic protein 15
BMPR1B bone morphogenetic protein receptor, type IB
C14ORF132 chromosome 14 open reading frame 132
C1ORF146 chromosome 1 open reading frame 146
CACHD1 cache domain containing 1
CADM2 cell adhesion molecule 2
CALCRL calcitonin receptor-like
CARD10 caspase recruitment domain family, member 10
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCDC85C coiled-coil domain containing 85C
CCL3 chemokine (C-C motif) ligand 3
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCL4 chemokine (C-C motif) ligand 4
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CD83 CD83 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CH25H cholesterol 25-hydroxylase
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CLDND2 claudin domain containing 2
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNOT6L CCR4-NOT transcription complex, subunit 6-like
COL4A6 collagen, type IV, alpha 6
CPE carboxypeptidase E
CTH cystathionine gamma-lyase
DBT dihydrolipoamide branched chain transacylase E2
DDAH1 dimethylarginine dimethylaminohydrolase 1
DLL1 delta-like 1 (Drosophila)
DNTT DNA nucleotidylexotransferase
DTX4 deltex 4, E3 ubiquitin ligase
EDNRB endothelin receptor type B
EGR2 early growth response 2
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELMO2 engulfment and cell motility 2
ERBB2IP erbb2 interacting protein
ERO1LB ERO1-like beta (S. cerevisiae)
FAM53C family with sequence similarity 53, member C
FAM8A1 family with sequence similarity 8, member A1
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FAT1 FAT atypical cadherin 1
FBXO30 F-box protein 30
FLG filaggrin
FRG2C FSHD region gene 2 family, member C
FSTL5 follistatin-like 5
FUT10 fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GAREM GRB2 associated, regulator of MAPK1
GDNF glial cell derived neurotrophic factor
GK2 glycerol kinase 2
GLUD1 glutamate dehydrogenase 1
GLUD2 glutamate dehydrogenase 2
GP9 glycoprotein IX (platelet)
GPM6A glycoprotein M6A
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
GSTM2 glutathione S-transferase mu 2 (muscle)
GUCA2B guanylate cyclase activator 2B (uroguanylin)
HEATR5A HEAT repeat containing 5A
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H4F histone cluster 1, H4f
HMHB1 histocompatibility (minor) HB-1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL1A interleukin 1, alpha
IL9 interleukin 9
JADE3 jade family PHD finger 3
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCTD20 potassium channel tetramerization domain containing 20
KCTD21 potassium channel tetramerization domain containing 21
KGFLP1 fibroblast growth factor 7 pseudogene
KIAA1549 KIAA1549
KIAA1671 KIAA1671
KIF1B kinesin family member 1B
KLHL5 kelch-like family member 5
KRT33A keratin 33A, type I
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LHX1 LIM homeobox 1
LINC00575 long intergenic non-protein coding RNA 575
LIX1 Lix1 homolog (chicken)
LONRF3 LON peptidase N-terminal domain and ring finger 3
LUZP2 leucine zipper protein 2
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
MBIP MAP3K12 binding inhibitory protein 1
MED12L mediator complex subunit 12-like
MEGF8 multiple EGF-like-domains 8
MYLIP myosin regulatory light chain interacting protein
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NADK2 NAD kinase 2, mitochondrial
NKAPL NFKB activating protein-like
NOTCH2 notch 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRARP NOTCH-regulated ankyrin repeat protein
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NYNRIN NYN domain and retroviral integrase containing
OR51G2 olfactory receptor, family 51, subfamily G, member 2
OR52A4P olfactory receptor, family 52, subfamily A, member 4, pseudogene
OR52E2 olfactory receptor, family 52, subfamily E, member 2
OR5AC2 olfactory receptor, family 5, subfamily AC, member 2
OSGIN2 oxidative stress induced growth inhibitor family member 2
OTUD1 OTU deubiquitinase 1
PARD3B par-3 family cell polarity regulator beta
PCDH10 protocadherin 10
PCDHA4 protocadherin alpha 4
PCDHB16 protocadherin beta 16
PCDHB5 protocadherin beta 5
PDLIM5 PDZ and LIM domain 5
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLSCR4 phospholipid scramblase 4
POM121L2 POM121 transmembrane nucleoporin-like 2
PPAP2B phosphatidic acid phosphatase type 2B
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PRKG2 protein kinase, cGMP-dependent, type II
PRODH proline dehydrogenase (oxidase) 1
PRPF38A pre-mRNA processing factor 38A
PRR5L proline rich 5 like
PRTG protogenin
PTPN21 protein tyrosine phosphatase, non-receptor type 21
QKI QKI, KH domain containing, RNA binding
RANBP3L RAN binding protein 3-like
RASA4 RAS p21 protein activator 4
RBM12 RNA binding motif protein 12
RBMXL1 RNA binding motif protein, X-linked-like 1
REC114 REC114 meiotic recombination protein
RFTN2 raftlin family member 2
RHOBTB3 Rho-related BTB domain containing 3
RICTOR RPTOR independent companion of MTOR, complex 2
RIPK2 receptor-interacting serine-threonine kinase 2
RNF141 ring finger protein 141
RNF180 ring finger protein 180
RNF182 ring finger protein 182
RNF39 ring finger protein 39
RNF5P1 ring finger protein 5, E3 ubiquitin protein ligase pseudogene 1
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL3L ribosomal protein L3-like
RSG1 REM2 and RAB-like small GTPase 1
RSPO3 R-spondin 3
RYR1 ryanodine receptor 1 (skeletal)
S1PR1 sphingosine-1-phosphate receptor 1
SALL2 spalt-like transcription factor 2
SCARNA15 small Cajal body-specific RNA 15
SCGB1C1 secretoglobin, family 1C, member 1
SCN7A sodium channel, voltage gated, type VII alpha subunit
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SFRP2 secreted frizzled-related protein 2
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SMAD5 SMAD family member 5
SNORA11D small nucleolar RNA, H/ACA box 11D
SNX18 sorting nexin 18
SNX2 sorting nexin 2
SOCS6 suppressor of cytokine signaling 6
SOX21 SRY (sex determining region Y)-box 21
SPEN spen family transcriptional repressor
SPIRE1 spire-type actin nucleation factor 1
SRR serine racemase
STON1 stonin 1
STON2 stonin 2
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4
SYTL4 synaptotagmin-like 4
TAAR5 trace amine associated receptor 5
TAS2R8 taste receptor, type 2, member 8
TIAM1 T-cell lymphoma invasion and metastasis 1
TMEM170A transmembrane protein 170A
TMEM47 transmembrane protein 47
TNF tumor necrosis factor
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNIK TRAF2 and NCK interacting kinase
TNS3 tensin 3
TRIM53AP tripartite motif containing 53A, pseudogene
TSPO2 translocator protein 2
USP50 ubiquitin specific peptidase 50
WFDC11 WAP four-disulfide core domain 11
WIPF2 WAS/WASL interacting protein family, member 2
YLPM1 YLP motif containing 1
ZDHHC2 zinc finger, DHHC-type containing 2
ZFX zinc finger protein, X-linked
ZIC3 Zic family member 3
ZNF134 zinc finger protein 134
ZNF275 zinc finger protein 275
ZNF319 zinc finger protein 319
ZNF542P zinc finger protein 542, pseudogene
ZNF592 zinc finger protein 592
ZNF609 zinc finger protein 609
ZNF614 zinc finger protein 614
ZNF615 zinc finger protein 615
ZNF649 zinc finger protein 649
ZNF770 zinc finger protein 770
ZNF772 zinc finger protein 772
ZNF780A zinc finger protein 780A

low expression

Symbol Name
APMAP adipocyte plasma membrane associated protein
COPS7B COP9 signalosome subunit 7B
COPS8 COP9 signalosome subunit 8
CSRP2BP CSRP2 binding protein
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
DUSP28 dual specificity phosphatase 28
EIF4E2 eukaryotic translation initiation factor 4E family member 2
ERICH1 glutamate-rich 1
MKKS McKusick-Kaufman syndrome
MRS2 MRS2 magnesium transporter
MTERF4 mitochondrial transcription termination factor 4
NCL nucleolin
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
RWDD2B RWD domain containing 2B
SNRPB2 small nuclear ribonucleoprotein polypeptide B
STK25 serine/threonine kinase 25
ZNF133 zinc finger protein 133