Brain Lower Grade Glioma_LGG_TCGA-P5-A5EZ-01A-11R-A27Q-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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385 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-P5-A5EZ-01A-11R-A27Q-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADRA2B adrenoceptor alpha 2B
AGFG1 ArfGAP with FG repeats 1
AGK acylglycerol kinase
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C4 aldo-keto reductase family 1, member C4
ALCAM activated leukocyte cell adhesion molecule
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
AMOTL2 angiomotin like 2
ANKRD13A ankyrin repeat domain 13A
ANKRD16 ankyrin repeat domain 16
ANXA8L1 annexin A8-like 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGAP17 Rho GTPase activating protein 17
ARHGAP23 Rho GTPase activating protein 23
ARRDC3 arrestin domain containing 3
ASPA aspartoacylase
ATG4C autophagy related 4C, cysteine peptidase
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCL2L1 BCL2-like 1
BCORP1 BCL6 corepressor pseudogene 1
BEND7 BEN domain containing 7
BICD2 bicaudal D homolog 2 (Drosophila)
BMF Bcl2 modifying factor
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRD7 bromodomain containing 7
C10ORF90 chromosome 10 open reading frame 90
C15ORF43 chromosome 15 open reading frame 43
C21ORF91 chromosome 21 open reading frame 91
C2ORF83 chromosome 2 open reading frame 83
C7ORF13 chromosome 7 open reading frame 13
C8B complement component 8, beta polypeptide
CA14 carbonic anhydrase XIV
CATSPERG catsper channel auxiliary subunit gamma
CC2D1B coiled-coil and C2 domain containing 1B
CCDC125 coiled-coil domain containing 125
CCL25 chemokine (C-C motif) ligand 25
CCL5 chemokine (C-C motif) ligand 5
CCNB3 cyclin B3
CCR2 chemokine (C-C motif) receptor 2
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2
CD200R1L CD200 receptor 1-like
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD8A CD8a molecule
CD8B CD8b molecule
CDC123 cell division cycle 123
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDK19 cyclin-dependent kinase 19
CEP85 centrosomal protein 85kDa
CFAP20 cilia and flagella associated protein 20
CLNK cytokine-dependent hematopoietic cell linker
CMTR2 cap methyltransferase 2
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNTN2 contactin 2 (axonal)
COL11A1 collagen, type XI, alpha 1
CRIPT cysteine-rich PDZ-binding protein
CRLF3 cytokine receptor-like factor 3
CRLS1 cardiolipin synthase 1
CRYBG3 beta-gamma crystallin domain containing 3
CRYGC crystallin, gamma C
CST7 cystatin F (leukocystatin)
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTSW cathepsin W
CXCR3 chemokine (C-X-C motif) receptor 3
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2
DAD1P1 defender against cell death 1 pseudogene 1
DCAF16 DDB1 and CUL4 associated factor 16
DCAF17 DDB1 and CUL4 associated factor 17
DCLRE1C DNA cross-link repair 1C
DCP1A decapping mRNA 1A
DCT dopachrome tautomerase
DEFB118 defensin, beta 118
DENND6A DENN/MADD domain containing 6A
DEPDC7 DEP domain containing 7
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DIXDC1 DIX domain containing 1
DLEU2L deleted in lymphocytic leukemia 2-like
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
DUSP19 dual specificity phosphatase 19
DUSP7 dual specificity phosphatase 7
EOMES eomesodermin
FA2H fatty acid 2-hydroxylase
FAM102A family with sequence similarity 102, member A
FAM107B family with sequence similarity 107, member B
FAM124A family with sequence similarity 124A
FAM127B family with sequence similarity 127, member B
FAM188A family with sequence similarity 188, member A
FAM193A family with sequence similarity 193, member A
FAM208B family with sequence similarity 208, member B
FAM47B family with sequence similarity 47, member B
FAM47C family with sequence similarity 47, member C
FAM60A family with sequence similarity 60, member A
FAM71D family with sequence similarity 71, member D
FASLG Fas ligand (TNF superfamily, member 6)
FASTKD1 FAST kinase domains 1
FBL fibrillarin
FBXO18 F-box protein, helicase, 18
FIBIN fin bud initiation factor homolog (zebrafish)
FITM1 fat storage-inducing transmembrane protein 1
FKBP7 FK506 binding protein 7
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXI3 forkhead box I3
FOXN2 forkhead box N2
FOXQ1 forkhead box Q1
FRK fyn-related Src family tyrosine kinase
FRMD4B FERM domain containing 4B
FXYD4 FXYD domain containing ion transport regulator 4
GAGE10 G antigen 10
GDAP2 ganglioside induced differentiation associated protein 2
GDI2 GDP dissociation inhibitor 2
GIMAP6 GTPase, IMAP family member 6
GJA9 gap junction protein, alpha 9, 59kDa
GLTP glycolipid transfer protein
GML glycosylphosphatidylinositol anchored molecule like
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GOLGA6D golgin A6 family, member D
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
GPR180 G protein-coupled receptor 180
GPR62 G protein-coupled receptor 62
GPX6 glutathione peroxidase 6
GRK4 G protein-coupled receptor kinase 4
GRK7 G protein-coupled receptor kinase 7
GSDMC gasdermin C
GSTM3 glutathione S-transferase mu 3 (brain)
GTPBP4 GTP binding protein 4
GUCA2B guanylate cyclase activator 2B (uroguanylin)
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
GZMK granzyme K (granzyme 3; tryptase II)
HCG4B HLA complex group 4B (non-protein coding)
HDGFL1 hepatoma derived growth factor-like 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2AE histone cluster 1, H2ae
HIST1H2AK histone cluster 1, H2ak
HIST1H2BO histone cluster 1, H2bo
HIST1H3D histone cluster 1, H3d
HIST1H4H histone cluster 1, H4h
HIST1H4I histone cluster 1, H4i
HIST2H2BE histone cluster 2, H2be
HM13 histocompatibility (minor) 13
HMGB4 high mobility group box 4
HMGN4 high mobility group nucleosomal binding domain 4
HOXD1 homeobox D1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA14 heat shock 70kDa protein 14
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
IDI2 isopentenyl-diphosphate delta isomerase 2
IKZF4 IKAROS family zinc finger 4 (Eos)
IL2RB interleukin 2 receptor, beta
ILDR1 immunoglobulin-like domain containing receptor 1
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
INTS9 integrator complex subunit 9
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
JAM3 junctional adhesion molecule 3
JOSD1 Josephin domain containing 1
KCNIP4-IT1 KCNIP4 intronic transcript 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIN Kin17 DNA and RNA binding protein
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KLF13 Kruppel-like factor 13
KLK6 kallikrein-related peptidase 6
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KRT37 keratin 37, type I
KRTAP9-9 keratin associated protein 9-9
LACTB2 lactamase, beta 2
LARP4B La ribonucleoprotein domain family, member 4B
LIN7C lin-7 homolog C (C. elegans)
LINC00028 long intergenic non-protein coding RNA 28
LINC00264 long intergenic non-protein coding RNA 264
LINC00469 long intergenic non-protein coding RNA 469
LINC00589 long intergenic non-protein coding RNA 589
LINS lines homolog (Drosophila)
LOC100271832 uncharacterized LOC100271832
LOC145474 uncharacterized LOC145474
LOC400794 uncharacterized LOC400794
LOC647859 occludin pseudogene
LOC729609 uncharacterized LOC729609
LRIF1 ligand dependent nuclear receptor interacting factor 1
LRRC8D leucine rich repeat containing 8 family, member D
LURAP1L leucine rich adaptor protein 1-like
LYAR Ly1 antibody reactive
MAGEC3 melanoma antigen family C3
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MARS2 methionyl-tRNA synthetase 2, mitochondrial
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MGC16142 uncharacterized protein MGC16142
MGC72080 MGC72080 pseudogene
MIXL1 Mix paired-like homeobox
MRGPRX4 MAS-related GPR, member X4
MTFR1 mitochondrial fission regulator 1
MTMR2 myotubularin related protein 2
MTPAP mitochondrial poly(A) polymerase
MVB12B multivesicular body subunit 12B
MYO1D myosin ID
N4BP1 NEDD4 binding protein 1
NIP7 NIP7, nucleolar pre-rRNA processing protein
NIPAL4 NIPA-like domain containing 4
NKAIN1 Na+/K+ transporting ATPase interacting 1
NKX2-8 NK2 homeobox 8
NOL4L nucleolar protein 4-like
NOL8 nucleolar protein 8
NOMO1 NODAL modulator 1
NOP14 NOP14 nucleolar protein
NPVF neuropeptide VF precursor
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NSUN6 NOP2/Sun domain family, member 6
OR13C8 olfactory receptor, family 13, subfamily C, member 8
OR4K15 olfactory receptor, family 4, subfamily K, member 15
OR4M1 olfactory receptor, family 4, subfamily M, member 1
OR4N2 olfactory receptor, family 4, subfamily N, member 2
OR52D1 olfactory receptor, family 52, subfamily D, member 1
OR5V1 olfactory receptor, family 5, subfamily V, member 1
OR6A2 olfactory receptor, family 6, subfamily A, member 2
OXSR1 oxidative stress responsive 1
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARD6G par-6 family cell polarity regulator gamma
PCBP1 poly(rC) binding protein 1
PDC phosducin
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PELI1 pellino E3 ubiquitin protein ligase 1
PHF8 PHD finger protein 8
PHYH phytanoyl-CoA 2-hydroxylase
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PITRM1 pitrilysin metallopeptidase 1
PKD2L2 polycystic kidney disease 2-like 2
PKP4 plakophilin 4
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PM20D1 peptidase M20 domain containing 1
POC5 POC5 centriolar protein
PODN podocan
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPAP2C phosphatidic acid phosphatase type 2C
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP1R21 protein phosphatase 1, regulatory subunit 21
PRAMEF10 PRAME family member 10
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PRPF18 pre-mRNA processing factor 18
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PSG4 pregnancy specific beta-1-glycoprotein 4
PTCHD3 patched domain containing 3
PTMA prothymosin, alpha
PTPRH protein tyrosine phosphatase, receptor type, H
PUS10 pseudouridylate synthase 10
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAB19 RAB19, member RAS oncogene family
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RBM17 RNA binding motif protein 17
RBMXL3 RNA binding motif protein, X-linked-like 3
RCC1 regulator of chromosome condensation 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGL4 ral guanine nucleotide dissociation stimulator-like 4
RHD Rh blood group, D antigen
RHOBTB1 Rho-related BTB domain containing 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPIA ribose 5-phosphate isomerase A
RRP1B ribosomal RNA processing 1B
RSU1 Ras suppressor protein 1
RTP3 receptor (chemosensory) transporter protein 3
RYBP RING1 and YY1 binding protein
S1PR5 sphingosine-1-phosphate receptor 5
SASS6 spindle assembly 6 homolog (C. elegans)
SCARNA20 small Cajal body-specific RNA 20
SCLY selenocysteine lyase
SCN3A sodium channel, voltage gated, type III alpha subunit
SCP2 sterol carrier protein 2
SDHAF3 succinate dehydrogenase complex assembly factor 3
SHROOM4 shroom family member 4
SIX4 SIX homeobox 4
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC45A3 solute carrier family 45, member 3
SLITRK6 SLIT and NTRK-like family, member 6
SMAD2 SMAD family member 2
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMC6 structural maintenance of chromosomes 6
SMIM21 small integral membrane protein 21
SMR3A submaxillary gland androgen regulated protein 3A
SNORA4 small nucleolar RNA, H/ACA box 4
SNX15 sorting nexin 15
SNX29P2 sorting nexin 29 pseudogene 2
SOX4 SRY (sex determining region Y)-box 4
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPOPL speckle-type POZ protein-like
SQLE squalene epoxidase
ST18 suppression of tumorigenicity 18, zinc finger
STK38 serine/threonine kinase 38
STK4 serine/threonine kinase 4
STXBP3 syntaxin binding protein 3
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TARP TCR gamma alternate reading frame protein
TDGF1 teratocarcinoma-derived growth factor 1
TDGF1P3 teratocarcinoma-derived growth factor 1 pseudogene 3
TESK2 testis-specific kinase 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFEB transcription factor EB
TGDS TDP-glucose 4,6-dehydratase
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THOC5 THO complex 5
TJAP1 tight junction associated protein 1 (peripheral)
TLR9 toll-like receptor 9
TMC7 transmembrane channel-like 7
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM123 transmembrane protein 123
TMEM128 transmembrane protein 128
TMEM33 transmembrane protein 33
TMEM39B transmembrane protein 39B
TMEM57 transmembrane protein 57
TMEM64 transmembrane protein 64
TNS3 tensin 3
TOPAZ1 testis and ovary specific PAZ domain containing 1
TOX3 TOX high mobility group box family member 3
TPTEP1 transmembrane phosphatase with tensin homology pseudogene 1
TRIM59 tripartite motif containing 59
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRMT6 tRNA methyltransferase 6
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TSEN15 TSEN15 tRNA splicing endonuclease subunit
TSPYL6 TSPY-like 6
TTTY10 testis-specific transcript, Y-linked 10 (non-protein coding)
TTTY15 testis-specific transcript, Y-linked 15 (non-protein coding)
TXLNGY taxilin gamma pseudogene, Y-linked
UBASH3A ubiquitin associated and SH3 domain containing A
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGDH UDP-glucose 6-dehydrogenase
UNC93A unc-93 homolog A (C. elegans)
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP6NL USP6 N-terminal like
WDTC1 WD and tetratricopeptide repeats 1
WFDC6 WAP four-disulfide core domain 6
WNT5A wingless-type MMTV integration site family, member 5A
XCL2 chemokine (C motif) ligand 2
XRCC6BP1 XRCC6 binding protein 1
YPEL2 yippee-like 2 (Drosophila)
ZAN zonadhesin (gene/pseudogene)
ZBTB49 zinc finger and BTB domain containing 49
ZDHHC9 zinc finger, DHHC-type containing 9
ZFP69B ZFP69 zinc finger protein B
ZMYM6 zinc finger, MYM-type 6
ZNF182 zinc finger protein 182
ZNF197 zinc finger protein 197
ZNF208 zinc finger protein 208
ZNF257 zinc finger protein 257
ZNF267 zinc finger protein 267
ZNF35 zinc finger protein 35
ZNF382 zinc finger protein 382
ZNF431 zinc finger protein 431
ZNF461 zinc finger protein 461
ZNF506 zinc finger protein 506
ZNF507 zinc finger protein 507
ZNF529 zinc finger protein 529
ZNF560 zinc finger protein 560
ZNF565 zinc finger protein 565
ZNF566 zinc finger protein 566
ZNF567 zinc finger protein 567
ZNF569 zinc finger protein 569
ZNF683 zinc finger protein 683
ZNF684 zinc finger protein 684
ZNF764 zinc finger protein 764
ZNF793 zinc finger protein 793
ZNF799 zinc finger protein 799
ZNF804A zinc finger protein 804A
ZNF98 zinc finger protein 98

low expression

Symbol Name
CSNK1D casein kinase 1, delta
GMPR2 guanosine monophosphate reductase 2
MPPE1 metallophosphoesterase 1
OCIAD1 OCIA domain containing 1
RWDD2A RWD domain containing 2A
SNX14 sorting nexin 14
ZCCHC18 zinc finger, CCHC domain containing 18