Brain Lower Grade Glioma_LGG_TCGA-P5-A5F2-01A-11R-A28M-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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438 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-P5-A5F2-01A-11R-A28M-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AADAC arylacetamide deacetylase
ABRA actin binding Rho activating protein
ACKR3 atypical chemokine receptor 3
ACOT13 acyl-CoA thioesterase 13
ACSM6 acyl-CoA synthetase medium-chain family member 6
ACTL7B actin-like 7B
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADCY2 adenylate cyclase 2 (brain)
ADGRF1 adhesion G protein-coupled receptor F1
ADIPOR2 adiponectin receptor 2
ADRB3 adrenoceptor beta 3
AK8 adenylate kinase 8
AKR1C1 aldo-keto reductase family 1, member C1
AMOTL1 angiomotin like 1
ANGPT4 angiopoietin 4
ANXA8 annexin A8
ANXA8L1 annexin A8-like 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGAP10 Rho GTPase activating protein 10
ARL13A ADP-ribosylation factor-like 13A
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASB15 ankyrin repeat and SOCS box containing 15
ASB3 ankyrin repeat and SOCS box containing 3
ASIC5 acid sensing (proton gated) ion channel family member 5
ASPH aspartate beta-hydroxylase
ATG2A autophagy related 2A
ATOH8 atonal homolog 8 (Drosophila)
ATP11AUN ATP11A upstream neighbor
ATP13A4 ATPase type 13A4
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1
AWAT1 acyl-CoA wax alcohol acyltransferase 1
BAIAP2 BAI1-associated protein 2
BBS1 Bardet-Biedl syndrome 1
BBS2 Bardet-Biedl syndrome 2
BBS5 Bardet-Biedl syndrome 5
BCAS3 breast carcinoma amplified sequence 3
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BEND5 BEN domain containing 5
BOC BOC cell adhesion associated, oncogene regulated
BSDC1 BSD domain containing 1
C10ORF99 chromosome 10 open reading frame 99
C12ORF29 chromosome 12 open reading frame 29
C17ORF97 chromosome 17 open reading frame 97
C1ORF198 chromosome 1 open reading frame 198
C1ORF94 chromosome 1 open reading frame 94
C2CD2 C2 calcium-dependent domain containing 2
C2ORF69 chromosome 2 open reading frame 69
C3ORF36 chromosome 3 open reading frame 36
C6ORF62 chromosome 6 open reading frame 62
C9ORF43 chromosome 9 open reading frame 43
CAB39L calcium binding protein 39-like
CALCOCO2 calcium binding and coiled-coil domain 2
CALML4 calmodulin-like 4
CAPN7 calpain 7
CASP14 caspase 14, apoptosis-related cysteine peptidase
CBFB core-binding factor, beta subunit
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CCDC105 coiled-coil domain containing 105
CCDC160 coiled-coil domain containing 160
CCDC181 coiled-coil domain containing 181
CCDC24 coiled-coil domain containing 24
CDC14A cell division cycle 14A
CDC20B cell division cycle 20B
CDH16 cadherin 16, KSP-cadherin
CDH20 cadherin 20, type 2
CDH26 cadherin 26
CDIP1 cell death-inducing p53 target 1
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CEP70 centrosomal protein 70kDa
CFAP70 cilia and flagella associated protein 70
CFHR4 complement factor H-related 4
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLC Charcot-Leyden crystal galectin
CLPSL2 colipase-like 2
CNN2 calponin 2
COQ10A coenzyme Q10 homolog A (S. cerevisiae)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRHR2 corticotropin releasing hormone receptor 2
CRYL1 crystallin, lambda 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CT45A4 cancer/testis antigen family 45, member A4
CTH cystathionine gamma-lyase
CXCL17 chemokine (C-X-C motif) ligand 17
CYB5D1 cytochrome b5 domain containing 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYS1 cystin 1
DBT dihydrolipoamide branched chain transacylase E2
DEFB119 defensin, beta 119
DENND6B DENN/MADD domain containing 6B
DISP1 dispatched homolog 1 (Drosophila)
DNAL4 dynein, axonemal, light chain 4
DNMBP-AS1 DNMBP antisense RNA 1
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
DUSP2 dual specificity phosphatase 2
EAF2 ELL associated factor 2
EBF1 early B-cell factor 1
EFCAB6 EF-hand calcium binding domain 6
EFCAB7 EF-hand calcium binding domain 7
EFNA3 ephrin-A3
EGR3 early growth response 3
EGR4 early growth response 4
EML6 echinoderm microtubule associated protein like 6
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
EP400NL EP400 N-terminal like
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ERC2-IT1 ERC2 intronic transcript 1
ETFDH electron-transferring-flavoprotein dehydrogenase
ETNPPL ethanolamine-phosphate phospho-lyase
EVPLL envoplakin-like
F5 coagulation factor V (proaccelerin, labile factor)
FADS3 fatty acid desaturase 3
FAM110A family with sequence similarity 110, member A
FAM138B family with sequence similarity 138, member B
FAM153A family with sequence similarity 153, member A
FAM161A family with sequence similarity 161, member A
FAM169A family with sequence similarity 169, member A
FAM171B family with sequence similarity 171, member B
FAM65B family with sequence similarity 65, member B
FAM71C family with sequence similarity 71, member C
FAM8A1 family with sequence similarity 8, member A1
FAP fibroblast activation protein, alpha
FBXO32 F-box protein 32
FBXO42 F-box protein 42
FEZF2 FEZ family zinc finger 2
FMNL3 formin-like 3
FMO5 flavin containing monooxygenase 5
FRG2B FSHD region gene 2 family, member B
FTO fat mass and obesity associated
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GBX2 gastrulation brain homeobox 2
GDF2 growth differentiation factor 2
GEMIN8 gem (nuclear organelle) associated protein 8
GLP2R glucagon-like peptide 2 receptor
GLUL glutamate-ammonia ligase
GMNN geminin, DNA replication inhibitor
GOLGA2P3Y golgin A2 pseudogene 3, Y-linked
GPC4 glypican 4
GPR3 G protein-coupled receptor 3
GPR68 G protein-coupled receptor 68
GREB1L growth regulation by estrogen in breast cancer-like
GRHL1 grainyhead-like 1 (Drosophila)
GRHL2 grainyhead-like 2 (Drosophila)
GRTP1 growth hormone regulated TBC protein 1
GTSF1L gametocyte specific factor 1-like
GYS2 glycogen synthase 2 (liver)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BC histone cluster 1, H2bc
HIST1H2BE histone cluster 1, H2be
HIST1H3D histone cluster 1, H3d
HIST2H2BE histone cluster 2, H2be
HIST2H3D histone cluster 2, H3d
HIST2H4A histone cluster 2, H4a
HIST3H3 histone cluster 3, H3
HMOX2 heme oxygenase 2
HNMT histamine N-methyltransferase
HOMEZ homeobox and leucine zipper encoding
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
HVCN1 hydrogen voltage gated channel 1
IFNA6 interferon, alpha 6
IFT88 intraflagellar transport 88
IGSF22 immunoglobulin superfamily, member 22
IGSF3 immunoglobulin superfamily, member 3
IL17D interleukin 17D
ILK integrin-linked kinase
INTS10 integrator complex subunit 10
IPW imprinted in Prader-Willi syndrome (non-protein coding)
IQSEC2 IQ motif and Sec7 domain 2
IRX3 iroquois homeobox 3
JADE1 jade family PHD finger 1
JUP junction plakoglobin
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCTD13 potassium channel tetramerization domain containing 13
KCTD4 potassium channel tetramerization domain containing 4
KCTD6 potassium channel tetramerization domain containing 6
KDM3A lysine (K)-specific demethylase 3A
KGFLP1 fibroblast growth factor 7 pseudogene
KIAA1407 KIAA1407
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KLF15 Kruppel-like factor 15
KLHL21 kelch-like family member 21
KLHL3 kelch-like family member 3
KLHL40 kelch-like family member 40
KLHL41 kelch-like family member 41
KRT19 keratin 19, type I
KRT23 keratin 23, type I
KRT7 keratin 7, type II
KRT77 keratin 77, type II
KRTAP10-11 keratin associated protein 10-11
KRTAP10-3 keratin associated protein 10-3
KRTAP3-3 keratin associated protein 3-3
KRTAP4-1 keratin associated protein 4-1
LDHD lactate dehydrogenase D
LDOC1 leucine zipper, down-regulated in cancer 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LIFR leukemia inhibitory factor receptor alpha
LIM2 lens intrinsic membrane protein 2, 19kDa
LINC00161 long intergenic non-protein coding RNA 161
LINC00244 long intergenic non-protein coding RNA 244
LINC00521 long intergenic non-protein coding RNA 521
LMLN leishmanolysin-like (metallopeptidase M8 family)
LMNTD1 lamin tail domain containing 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LOC100128076 protein tyrosine phosphatase pseudogene
LOC100130238 uncharacterized LOC100130238
LOC283731 uncharacterized LOC283731
LOC284379 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 pseudogene
LOC401127 WD repeat domain 5 pseudogene
LOC646214 p21 protein (Cdc42/Rac)-activated kinase 2 pseudogene
LOC646471 uncharacterized LOC646471
LOC728989 phosphodiesterase 4D interacting protein pseudogene
LRIF1 ligand dependent nuclear receptor interacting factor 1
LYPD3 LY6/PLAUR domain containing 3
LYSMD2 LysM, putative peptidoglycan-binding, domain containing 2
MAGEA9B melanoma antigen family A9B
MAGEC3 melanoma antigen family C3
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAOA monoamine oxidase A
MAPK4 mitogen-activated protein kinase 4
MBIP MAP3K12 binding inhibitory protein 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
MDM1 Mdm1 nuclear protein homolog (mouse)
MED31 mediator complex subunit 31
MEGF9 multiple EGF-like-domains 9
MERTK MER proto-oncogene, tyrosine kinase
METTL7A methyltransferase like 7A
MMP28 matrix metallopeptidase 28
MNT MAX network transcriptional repressor
MOGAT1 monoacylglycerol O-acyltransferase 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MST1L macrophage stimulating 1-like
MXI1 MAX interactor 1, dimerization protein
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYH13 myosin, heavy chain 13, skeletal muscle
MYOM2 myomesin 2
N6AMT2 N-6 adenine-specific DNA methyltransferase 2 (putative)
NAP1L6 nucleosome assembly protein 1-like 6
NCKIPSD NCK interacting protein with SH3 domain
NCOA1 nuclear receptor coactivator 1
NFE2L1 nuclear factor, erythroid 2-like 1
NPHP3 nephronophthisis 3 (adolescent)
NPTX2 neuronal pentraxin II
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NT5C2 5'-nucleotidase, cytosolic II
NT5DC3 5'-nucleotidase domain containing 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OR10AD1 olfactory receptor, family 10, subfamily AD, member 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR1J2 olfactory receptor, family 1, subfamily J, member 2
OR1J4 olfactory receptor, family 1, subfamily J, member 4
OR1L3 olfactory receptor, family 1, subfamily L, member 3
OR1L4 olfactory receptor, family 1, subfamily L, member 4
OR1Q1 olfactory receptor, family 1, subfamily Q, member 1
OR2AK2 olfactory receptor, family 2, subfamily AK, member 2
OR2M1P olfactory receptor, family 2, subfamily M, member 1 pseudogene
OR2T10 olfactory receptor, family 2, subfamily T, member 10
OR2T6 olfactory receptor, family 2, subfamily T, member 6
OR4F29 olfactory receptor, family 4, subfamily F, member 29
OR6T1 olfactory receptor, family 6, subfamily T, member 1
OR7C1 olfactory receptor, family 7, subfamily C, member 1
OR8K1 olfactory receptor, family 8, subfamily K, member 1
OR9A4 olfactory receptor, family 9, subfamily A, member 4
OTOL1 otolin 1
OTUD3 OTU deubiquitinase 3
OXTR oxytocin receptor
PADI3 peptidyl arginine deiminase, type III
PAM peptidylglycine alpha-amidating monooxygenase
PAPLN papilin, proteoglycan-like sulfated glycoprotein
PAQR8 progestin and adipoQ receptor family member VIII
PARD3 par-3 family cell polarity regulator
PCTP phosphatidylcholine transfer protein
PDE4DIP phosphodiesterase 4D interacting protein
PDE8B phosphodiesterase 8B
PDILT protein disulfide isomerase-like, testis expressed
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PHACTR3 phosphatase and actin regulator 3
PHF19 PHD finger protein 19
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like
PI4KAP2 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
PIGX phosphatidylinositol glycan anchor biosynthesis, class X
PLA2G2F phospholipase A2, group IIF
PLEKHA7 pleckstrin homology domain containing, family A member 7
PNPLA8 patatin-like phospholipase domain containing 8
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POM121L2 POM121 transmembrane nucleoporin-like 2
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A
PPARA peroxisome proliferator-activated receptor alpha
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRG1 p53-responsive gene 1
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKX protein kinase, X-linked
PRODH2 proline dehydrogenase (oxidase) 2
PSG2 pregnancy specific beta-1-glycoprotein 2
PTCH2 patched 2
PTTG2 pituitary tumor-transforming 2
PUS10 pseudouridylate synthase 10
PVRL4 poliovirus receptor-related 4
PWARSN Prader Willi/Angelman region RNA, SNRPN neighbor
RAB10 RAB10, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RANBP3L RAN binding protein 3-like
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RFC5 replication factor C (activator 1) 5, 36.5kDa
RGCC regulator of cell cycle
RGS12 regulator of G-protein signaling 12
RHD Rh blood group, D antigen
RHOB ras homolog family member B
RHOBTB3 Rho-related BTB domain containing 3
RIPPLY1 ripply transcriptional repressor 1
RNF183 ring finger protein 183
RNPC3 RNA-binding region (RNP1, RRM) containing 3
RPTN repetin
RSG1 REM2 and RAB-like small GTPase 1
RTN4RL1 reticulon 4 receptor-like 1
RTN4RL2 reticulon 4 receptor-like 2
RUNX1-IT1 RUNX1 intronic transcript 1
RXRA retinoid X receptor, alpha
S100P S100 calcium binding protein P
SAFB2 scaffold attachment factor B2
SELL selectin L
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SERTAD1 SERTA domain containing 1
SGK3 serum/glucocorticoid regulated kinase family, member 3
SGMS1 sphingomyelin synthase 1
SHCBP1L SHC SH2-domain binding protein 1-like
SLC10A5 solute carrier family 10, member 5
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC25A42 solute carrier family 25, member 42
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC45A1 solute carrier family 45, member 1
SMAD3 SMAD family member 3
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMIM21 small integral membrane protein 21
SMS spermine synthase
SNORD115-7 small nucleolar RNA, C/D box 115-7
SNORD116-28 small nucleolar RNA, C/D box 116-28
SPERT spermatid associated
SPHAR S-phase response (cyclin related)
SPRR1A small proline-rich protein 1A
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STAB2 stabilin 2
STARD13 StAR-related lipid transfer (START) domain containing 13
STIM1 stromal interaction molecule 1
STK17B serine/threonine kinase 17b
STOX1 storkhead box 1
STX16 syntaxin 16
SUN2 Sad1 and UNC84 domain containing 2
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
SYBU syntabulin (syntaxin-interacting)
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TAOK2 TAO kinase 2
TAS2R1 taste receptor, type 2, member 1
TAS2R14 taste receptor, type 2, member 14
TBC1D29 TBC1 domain family, member 29
TBX2 T-box 2
TDRD5 tudor domain containing 5
TEX30 testis expressed 30
TFDP3 transcription factor Dp family, member 3
THEMIS thymocyte selection associated
THRA thyroid hormone receptor, alpha
TMEM100 transmembrane protein 100
TMEM133 transmembrane protein 133
TMEM233 transmembrane protein 233
TMEM59L transmembrane protein 59-like
TNRC6A trinucleotide repeat containing 6A
TNS4 tensin 4
TOB1 transducer of ERBB2, 1
TOP1P2 topoisomerase (DNA) I pseudogene 2
TPM1 tropomyosin 1 (alpha)
TSC22D1 TSC22 domain family, member 1
TSC22D3 TSC22 domain family, member 3
TSPYL2 TSPY-like 2
TYW5 tRNA-yW synthesizing protein 5
UBE2B ubiquitin-conjugating enzyme E2B
UCA1 urothelial cancer associated 1 (non-protein coding)
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UOX urate oxidase, pseudogene
USP40 ubiquitin specific peptidase 40
USP54 ubiquitin specific peptidase 54
VANGL2 VANGL planar cell polarity protein 2
VGLL1 vestigial-like family member 1
WDR11 WD repeat domain 11
WDR35 WD repeat domain 35
WDR87 WD repeat domain 87
WNT1 wingless-type MMTV integration site family, member 1
WNT3 wingless-type MMTV integration site family, member 3
WNT9B wingless-type MMTV integration site family, member 9B
XAGE1E X antigen family, member 1E
ZIC2 Zic family member 2
ZIC5 Zic family member 5
ZMAT1 zinc finger, matrin-type 1
ZMYND8 zinc finger, MYND-type containing 8
ZNF192P1 zinc finger protein 192 pseudogene 1
ZNF540 zinc finger protein 540
ZNF697 zinc finger protein 697
ZNRF3 zinc and ring finger 3

low expression

Symbol Name
AKIRIN2 akirin 2
ATG5 autophagy related 5
BAG5 BCL2-associated athanogene 5
COX19 COX19 cytochrome c oxidase assembly factor
ECHDC1 ethylmalonyl-CoA decarboxylase 1
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
LTV1 LTV1 ribosome biogenesis factor
MAP3K7 mitogen-activated protein kinase kinase kinase 7
PDCD2 programmed cell death 2
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RARS2 arginyl-tRNA synthetase 2, mitochondrial
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
SNW1 SNW domain containing 1
SNX14 sorting nexin 14
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
ZNF410 zinc finger protein 410
ZSCAN12 zinc finger and SCAN domain containing 12