Brain Lower Grade Glioma_LGG_TCGA-P5-A72X-01A-11R-A32Q-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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378 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-P5-A72X-01A-11R-A32Q-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABLIM1 actin binding LIM protein 1
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACVRL1 activin A receptor type II-like 1
ADCY2 adenylate cyclase 2 (brain)
ADCY4 adenylate cyclase 4
ADGRA2 adhesion G protein-coupled receptor A2
ADGRF5 adhesion G protein-coupled receptor F5
ADORA2A adenosine A2a receptor
ADORA2A-AS1 ADORA2A antisense RNA 1
AGAP11 ankyrin repeat and GTPase domain Arf GTPase activating protein 11
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALS2CL ALS2 C-terminal like
ANGPTL5 angiopoietin-like 5
ANO2 anoctamin 2, calcium activated chloride channel
ANTXR1 anthrax toxin receptor 1
APOE apolipoprotein E
APOL3 apolipoprotein L, 3
AQP7 aquaporin 7
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARSG arylsulfatase G
ASB18 ankyrin repeat and SOCS box containing 18
ASMTL acetylserotonin O-methyltransferase-like
ASRGL1 asparaginase like 1
ATN1 atrophin 1
ATP10A ATPase, class V, type 10A
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATXN2 ataxin 2
AXIN2 axin 2
BANP BTG3 associated nuclear protein
BRD4 bromodomain containing 4
C11ORF42 chromosome 11 open reading frame 42
C12ORF74 chromosome 12 open reading frame 74
C15ORF53 chromosome 15 open reading frame 53
C1ORF105 chromosome 1 open reading frame 105
C1QTNF7 C1q and tumor necrosis factor related protein 7
C2ORF83 chromosome 2 open reading frame 83
C6ORF201 chromosome 6 open reading frame 201
C9ORF78 chromosome 9 open reading frame 78
CACNG7 calcium channel, voltage-dependent, gamma subunit 7
CALHM2 calcium homeostasis modulator 2
CARD10 caspase recruitment domain family, member 10
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASP10 caspase 10, apoptosis-related cysteine peptidase
CBWD5 COBW domain containing 5
CCDC163P coiled-coil domain containing 163, pseudogene
CCDC69 coiled-coil domain containing 69
CCDC9 coiled-coil domain containing 9
CCM2L cerebral cavernous malformation 2-like
CCNK cyclin K
CD34 CD34 molecule
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK11B cyclin-dependent kinase 11B
CDY2B chromodomain protein, Y-linked, 2B
CEP250 centrosomal protein 250kDa
CGNL1 cingulin-like 1
CIC capicua transcriptional repressor
CIZ1 CDKN1A interacting zinc finger protein 1
CLEC14A C-type lectin domain family 14, member A
CLEC3B C-type lectin domain family 3, member B
CLPTM1 cleft lip and palate associated transmembrane protein 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
CSAG1 chondrosarcoma associated gene 1
CTNND2 catenin (cadherin-associated protein), delta 2
CXORF36 chromosome X open reading frame 36
CYB5R3 cytochrome b5 reductase 3
CYP4Z2P cytochrome P450, family 4, subfamily Z, polypeptide 2, pseudogene
CYYR1 cysteine/tyrosine-rich 1
DBP D site of albumin promoter (albumin D-box) binding protein
DCAKD dephospho-CoA kinase domain containing
DEGS2 delta(4)-desaturase, sphingolipid 2
DKK4 dickkopf WNT signaling pathway inhibitor 4
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
EDN3 endothelin 3
EGFL8 EGF-like-domain, multiple 8
EHD2 EH-domain containing 2
EPAS1 endothelial PAS domain protein 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERICH4 glutamate-rich 4
ESAM endothelial cell adhesion molecule
ESX1 ESX homeobox 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F10 coagulation factor X
FADS2 fatty acid desaturase 2
FAM110D family with sequence similarity 110, member D
FAM124B family with sequence similarity 124B
FAM171A1 family with sequence similarity 171, member A1
FAM65A family with sequence similarity 65, member A
FANCD2OS FANCD2 opposite strand
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FBXW4 F-box and WD repeat domain containing 4
FGD5 FYVE, RhoGEF and PH domain containing 5
FGD6 FYVE, RhoGEF and PH domain containing 6
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLNB filamin B, beta
FLT1 fms-related tyrosine kinase 1
FOXC1 forkhead box C1
FOXF2 forkhead box F2
FOXL2 forkhead box L2
FOXL2NB FOXL2 neighbor
FOXO4 forkhead box O4
FOXQ1 forkhead box Q1
FOXS1 forkhead box S1
FSCN2 fascin actin-bundling protein 2, retinal
GAB2 GRB2-associated binding protein 2
GAGE12J G antigen 12J
GAL3ST2 galactose-3-O-sulfotransferase 2
GATA2 GATA binding protein 2
GCM2 glial cells missing homolog 2 (Drosophila)
GDF10 growth differentiation factor 10
GDF2 growth differentiation factor 2
GIMAP1 GTPase, IMAP family member 1
GIMAP5 GTPase, IMAP family member 5
GIMAP6 GTPase, IMAP family member 6
GIMAP7 GTPase, IMAP family member 7
GIMAP8 GTPase, IMAP family member 8
GJB4 gap junction protein, beta 4, 30.3kDa
GJB5 gap junction protein, beta 5, 31.1kDa
GK2 glycerol kinase 2
GOLGA8IP golgin A8 family, member I, pseudogene
GOLIM4 golgi integral membrane protein 4
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
GPER1 G protein-coupled estrogen receptor 1
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GSDMC gasdermin C
GTF2A1L general transcription factor IIA, 1-like
GUSBP2 glucuronidase, beta pseudogene 2
HEG1 heart development protein with EGF-like domains 1
HERC2P2 hect domain and RLD 2 pseudogene 2
HIC1 hypermethylated in cancer 1
HIGD1B HIG1 hypoxia inducible domain family, member 1B
HMGN5 high mobility group nucleosome binding domain 5
HPSE2 heparanase 2 (inactive)
HRC histidine rich calcium binding protein
HRH4 histamine receptor H4
HSPA12B heat shock 70kD protein 12B
HTATSF1 HIV-1 Tat specific factor 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
HYAL1 hyaluronoglucosaminidase 1
IGSF1 immunoglobulin superfamily, member 1
IL12A interleukin 12A
INSL6 insulin-like 6
ITGA10 integrin, alpha 10
ITGA6 integrin, alpha 6
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
ITM2A integral membrane protein 2A
ITSN1 intersectin 1 (SH3 domain protein)
JAG2 jagged 2
KANK2 KN motif and ankyrin repeat domains 2
KANK3 KN motif and ankyrin repeat domains 3
KCNK16 potassium channel, two pore domain subfamily K, member 16
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2
KIAA1462 KIAA1462
KIF1C kinesin family member 1C
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1
KRT39 keratin 39, type I
KRTAP10-11 keratin associated protein 10-11
LAMA3 laminin, alpha 3
LEF1 lymphoid enhancer-binding factor 1
LEPR leptin receptor
LIMCH1 LIM and calponin homology domains 1
LINC00264 long intergenic non-protein coding RNA 264
LINC00469 long intergenic non-protein coding RNA 469
LOC100134368 uncharacterized LOC100134368
LOC100190986 uncharacterized LOC100190986
LOC100272216 uncharacterized LOC100272216
LOC145474 uncharacterized LOC145474
LOC285627 uncharacterized LOC285627
LOC388692 uncharacterized LOC388692
LOC644669 ankyrin repeat domain 30B pseudogene
LONRF3 LON peptidase N-terminal domain and ring finger 3
LSR lipolysis stimulated lipoprotein receptor
LY6K lymphocyte antigen 6 complex, locus K
MAP4 microtubule-associated protein 4
MARK4 MAP/microtubule affinity-regulating kinase 4
MARVELD2 MARVEL domain containing 2
MED12 mediator complex subunit 12
MEGF8 multiple EGF-like-domains 8
MFN2 mitofusin 2
MINK1 misshapen-like kinase 1
MKX mohawk homeobox
MLNR motilin receptor
MMRN2 multimerin 2
MROH7 maestro heat-like repeat family member 7
MSI1 musashi RNA-binding protein 1
MT1IP metallothionein 1I, pseudogene
MTSS1L metastasis suppressor 1-like
MUSTN1 musculoskeletal, embryonic nuclear protein 1
MYCT1 myc target 1
MYLK2 myosin light chain kinase 2
MYO1C myosin IC
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NET1 neuroepithelial cell transforming 1
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NLRP1 NLR family, pyrin domain containing 1
NLRP13 NLR family, pyrin domain containing 13
NOS3 nitric oxide synthase 3 (endothelial cell)
NOSTRIN nitric oxide synthase trafficking
NOTCH3 notch 3
NPR1 natriuretic peptide receptor 1
NPY4R neuropeptide Y receptor Y4
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRAP nebulin-related anchoring protein
NT5C1A 5'-nucleotidase, cytosolic IA
NXF2B nuclear RNA export factor 2B
OCLN occludin
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene)
OR1J1 olfactory receptor, family 1, subfamily J, member 1
OR2A2 olfactory receptor, family 2, subfamily A, member 2
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4
OR4N5 olfactory receptor, family 4, subfamily N, member 5
OR52A5 olfactory receptor, family 52, subfamily A, member 5
OR52B4 olfactory receptor, family 52, subfamily B, member 4 (gene/pseudogene)
OR52D1 olfactory receptor, family 52, subfamily D, member 1
OR52I2 olfactory receptor, family 52, subfamily I, member 2
OR52L1 olfactory receptor, family 52, subfamily L, member 1
OR6A2 olfactory receptor, family 6, subfamily A, member 2
OR8S1 olfactory receptor, family 8, subfamily S, member 1
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PALMD palmdelphin
PAX6 paired box 6
PC pyruvate carboxylase
PCDHGA12 protocadherin gamma subfamily A, 12
PEAR1 platelet endothelial aggregation receptor 1
PEBP4 phosphatidylethanolamine-binding protein 4
PER3 period circadian clock 3
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGM5 phosphoglucomutase 5
PHF2 PHD finger protein 2
PINK1 PTEN induced putative kinase 1
PKN3 protein kinase N3
PLXNB1 plexin B1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMCHL2 pro-melanin-concentrating hormone-like 2, pseudogene
PODXL podocalyxin-like
POM121L2 POM121 transmembrane nucleoporin-like 2
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP1R26 protein phosphatase 1, regulatory subunit 26
PPP1R2P1 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 1
PRKCH protein kinase C, eta
PRKD2 protein kinase D2
PROSER2 proline and serine rich 2
PRR12 proline rich 12
PRR5-ARHGAP8 PRR5-ARHGAP8 readthrough
PRRC2A proline-rich coiled-coil 2A
PSG3 pregnancy specific beta-1-glycoprotein 3
PTX4 pentraxin 4, long
RAB19 RAB19, member RAS oncogene family
RAET1E retinoic acid early transcript 1E
RASIP1 Ras interacting protein 1
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RBM17 RNA binding motif protein 17
RBM20 RNA binding motif protein 20
RBMS2 RNA binding motif, single stranded interacting protein 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RET ret proto-oncogene
RFPL4B ret finger protein-like 4B
RGMA repulsive guidance molecule family member a
RGS5 regulator of G-protein signaling 5
RILPL1 Rab interacting lysosomal protein-like 1
RNF39 ring finger protein 39
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RP1 retinitis pigmentosa 1 (autosomal dominant)
RRAD Ras-related associated with diabetes
RTP3 receptor (chemosensory) transporter protein 3
RYR1 ryanodine receptor 1 (skeletal)
SAMD4B sterile alpha motif domain containing 4B
SCARF1 scavenger receptor class F, member 1
SCGB1C1 secretoglobin, family 1C, member 1
SDHAP2 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SFTA1P surfactant associated 1, pseudogene
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
SGPP2 sphingosine-1-phosphate phosphatase 2
SH3BP2 SH3-domain binding protein 2
SHE Src homology 2 domain containing E
SIX5 SIX homeobox 5
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13
SLC23A3 solute carrier family 23, member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC35G6 solute carrier family 35, member G6
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMAD6 SMAD family member 6
SNORD116-4 small nucleolar RNA, C/D box 116-4
SORBS3 sorbin and SH3 domain containing 3
SOX17 SRY (sex determining region Y)-box 17
SOX18 SRY (sex determining region Y)-box 18
SOX7 SRY (sex determining region Y)-box 7
SPTBN1 spectrin, beta, non-erythrocytic 1
SRSF4 serine/arginine-rich splicing factor 4
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
STON2 stonin 2
SUFU suppressor of fused homolog (Drosophila)
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SYNM synemin, intermediate filament protein
SYPL2 synaptophysin-like 2
SYT15 synaptotagmin XV
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TAOK2 TAO kinase 2
TARP TCR gamma alternate reading frame protein
TBC1D3H TBC1 domain family, member 3H
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TCEAL2 transcription elongation factor A (SII)-like 2
TCF21 transcription factor 21
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCP10L t-complex 10-like
TDRD10 tudor domain containing 10
TEK TEK tyrosine kinase, endothelial
TEX38 testis expressed 38
TFE3 transcription factor binding to IGHM enhancer 3
TG thyroglobulin
TGM2 transglutaminase 2
THRSP thyroid hormone responsive
THSD1 thrombospondin, type I, domain containing 1
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMCO2 transmembrane and coiled-coil domains 2
TMOD3 tropomodulin 3 (ubiquitous)
TMPRSS11B transmembrane protease, serine 11B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNS1 tensin 1
TNS2 tensin 2
TPRX1 tetra-peptide repeat homeobox 1
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TRIL TLR4 interactor with leucine-rich repeats
TRIM8 tripartite motif containing 8
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TTN titin
TTTY10 testis-specific transcript, Y-linked 10 (non-protein coding)
TUBAL3 tubulin, alpha-like 3
USF2 upstream transcription factor 2, c-fos interacting
USHBP1 Usher syndrome 1C binding protein 1
UTRN utrophin
VWA2 von Willebrand factor A domain containing 2
WASF3 WAS protein family, member 3
WFDC8 WAP four-disulfide core domain 8
WNK2 WNK lysine deficient protein kinase 2
WTIP Wilms tumor 1 interacting protein
WWC2-AS2 WWC2 antisense RNA 2
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XYLT2 xylosyltransferase II
ZBTB46 zinc finger and BTB domain containing 46
ZDHHC8 zinc finger, DHHC-type containing 8
ZFP36L1 ZFP36 ring finger protein-like 1
ZIC2 Zic family member 2
ZIC3 Zic family member 3
ZIC5 Zic family member 5
ZMYND11 zinc finger, MYND-type containing 11
ZNF154 zinc finger protein 154
ZNF366 zinc finger protein 366
ZNF438 zinc finger protein 438
ZNF575 zinc finger protein 575
ZNF592 zinc finger protein 592
ZNF835 zinc finger protein 835

low expression

Symbol Name
LCLAT1 lysocardiolipin acyltransferase 1
NUDCD2 NudC domain containing 2
ORC4 origin recognition complex, subunit 4
RBM45 RNA binding motif protein 45