Brain Lower Grade Glioma_LGG_TCGA-P5-A737-01A-11R-A32Q-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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380 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-P5-A737-01A-11R-A32Q-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
AGER advanced glycosylation end product-specific receptor
AIRE autoimmune regulator
AMER3 APC membrane recruitment protein 3
AMOTL2 angiomotin like 2
ANK1 ankyrin 1, erythrocytic
ANXA8L1 annexin A8-like 1
AQP6 aquaporin 6, kidney specific
ARL17B ADP-ribosylation factor-like 17B
ARL5C ADP-ribosylation factor-like 5C
ARPIN actin-related protein 2/3 complex inhibitor
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ASAP1-IT1 ASAP1 intronic transcript 1
ASCL3 achaete-scute family bHLH transcription factor 3
ASGR1 asialoglycoprotein receptor 1
ATCAY ataxia, cerebellar, Cayman type
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4
BMPER BMP binding endothelial regulator
BOC BOC cell adhesion associated, oncogene regulated
BPIFB2 BPI fold containing family B, member 2
BRD1 bromodomain containing 1
BRD3 bromodomain containing 3
C11ORF95 chromosome 11 open reading frame 95
C15ORF53 chromosome 15 open reading frame 53
C16ORF82 chromosome 16 open reading frame 82
C17ORF50 chromosome 17 open reading frame 50
C20ORF196 chromosome 20 open reading frame 196
C22ORF46 chromosome 22 open reading frame 46
C5ORF38 chromosome 5 open reading frame 38
C9ORF153 chromosome 9 open reading frame 153
CA8 carbonic anhydrase VIII
CABIN1 calcineurin binding protein 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CASC3 cancer susceptibility candidate 3
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CCAR2 cell cycle and apoptosis regulator 2
CCDC101 coiled-coil domain containing 101
CCDC120 coiled-coil domain containing 120
CCDC185 coiled-coil domain containing 185
CCSER2 coiled-coil serine-rich protein 2
CDH24 cadherin 24, type 2
CDHR1 cadherin-related family member 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CECR2 cat eye syndrome chromosome region, candidate 2
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CEP250 centrosomal protein 250kDa
CHD7 chromodomain helicase DNA binding protein 7
CHERP calcium homeostasis endoplasmic reticulum protein
CHGB chromogranin B
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLDN14 claudin 14
CLEC3A C-type lectin domain family 3, member A
CLLU1 chronic lymphocytic leukemia up-regulated 1
CLRN1-AS1 CLRN1 antisense RNA 1
COX20 COX20 cytochrome c oxidase assembly factor
CPXM1 carboxypeptidase X (M14 family), member 1
CREBBP CREB binding protein
CRLS1 cardiolipin synthase 1
CSNK1E casein kinase 1, epsilon
CST9L cystatin 9-like
CUX1 cut-like homeobox 1
CXADRP2 coxsackie virus and adenovirus receptor pseudogene 2
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP27C1 cytochrome P450, family 27, subfamily C, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DBN1 drebrin 1
DCAF8L1 DDB1 and CUL4 associated factor 8-like 1
DCX doublecortin
DEFB132 defensin, beta 132
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DMRTB1 DMRT-like family B with proline-rich C-terminal, 1
DPPA5 developmental pluripotency associated 5
DPYSL3 dihydropyrimidinase-like 3
DSCR9 Down syndrome critical region 9 (non-protein coding)
ECE2 endothelin converting enzyme 2
EFS embryonal Fyn-associated substrate
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF3C eukaryotic translation initiation factor 3, subunit C
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
EP300 E1A binding protein p300
EXOC3-AS1 EXOC3 antisense RNA 1
F9 coagulation factor IX
FAM107A family with sequence similarity 107, member A
FAM109A family with sequence similarity 109, member A
FAM110B family with sequence similarity 110, member B
FAM181B family with sequence similarity 181, member B
FETUB fetuin B
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ13224 uncharacterized LOC79857
FOXI2 forkhead box I2
FOXO4 forkhead box O4
FXYD6 FXYD domain containing ion transport regulator 6
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GCSH glycine cleavage system protein H (aminomethyl carrier)
GDF11 growth differentiation factor 11
GFRAL GDNF family receptor alpha like
GHRH growth hormone releasing hormone
GJD2 gap junction protein, delta 2, 36kDa
GLIS1 GLIS family zinc finger 1
GLTPD2 glycolipid transfer protein domain containing 2
GMEB2 glucocorticoid modulatory element binding protein 2
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR148 G protein-coupled receptor 148
GPR179 G protein-coupled receptor 179
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GRID2IP glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
GRIK2 glutamate receptor, ionotropic, kainate 2
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
GTPBP1 GTP binding protein 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HAR1B highly accelerated region 1B (non-protein coding)
HDAC4 histone deacetylase 4
HIC2 hypermethylated in cancer 2
HIPK2 homeodomain interacting protein kinase 2
HIRA histone cell cycle regulator
HIRIP3 HIRA interacting protein 3
HMGN5 high mobility group nucleosome binding domain 5
HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HRK harakiri, BCL2 interacting protein
HRNR hornerin
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IDNK idnK, gluconokinase homolog (E. coli)
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1
INSM2 insulinoma-associated 2
IRF2BPL interferon regulatory factor 2 binding protein-like
IRX2 iroquois homeobox 2
JPH4 junctophilin 4
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIF1C kinesin family member 1C
KIF21B kinesin family member 21B
KIF3B kinesin family member 3B
KLF1 Kruppel-like factor 1 (erythroid)
KRT37 keratin 37, type I
KRT74 keratin 74, type II
LCAT lecithin-cholesterol acyltransferase
LDOC1L leucine zipper, down-regulated in cancer 1-like
LHFPL4 lipoma HMGIC fusion partner-like 4
LHX5 LIM homeobox 5
LINC01550 long intergenic non-protein coding RNA 1550
LOC100133985 uncharacterized LOC100133985
LOC100268168 uncharacterized LOC100268168
LOC154449 uncharacterized LOC154449
LOC283332 uncharacterized LOC283332
LOC441454 prothymosin, alpha pseudogene
LOC652276 potassium channel tetramerization domain containing 5 pseudogene
LOC729609 uncharacterized LOC729609
LOR loricrin
LPPR1 lipid phosphate phosphatase-related protein type 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
LRIT2 leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
LRRC37A leucine rich repeat containing 37A
LRRC37A2 leucine rich repeat containing 37, member A2
LRRC74A leucine rich repeat containing 74A
MAGEF1 melanoma antigen family F1
MAP4 microtubule-associated protein 4
MARC1 mitochondrial amidoxime reducing component 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MAX MYC associated factor X
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1
MEX3A mex-3 RNA binding family member A
MEX3B mex-3 RNA binding family member B
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MMP27 matrix metallopeptidase 27
MN1 meningioma (disrupted in balanced translocation) 1
MORC2 MORC family CW-type zinc finger 2
MTSS1L metastasis suppressor 1-like
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
MYO18A myosin XVIIIA
MYOM1 myomesin 1
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NANOG Nanog homeobox
NAP1L1 nucleosome assembly protein 1-like 1
NCAM1 neural cell adhesion molecule 1
NCL nucleolin
NCOA5 nuclear receptor coactivator 5
NCOR2 nuclear receptor corepressor 2
NF2 neurofibromin 2 (merlin)
NFIB nuclear factor I/B
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NFYB nuclear transcription factor Y, beta
NKD1 naked cuticle homolog 1 (Drosophila)
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOMO1 NODAL modulator 1
NOMO2 NODAL modulator 2
NOTCH1 notch 1
NOX3 NADPH oxidase 3
NSRP1 nuclear speckle splicing regulatory protein 1
NSUN5 NOP2/Sun domain family, member 5
NTNG2 netrin G2
NUTM2D NUT family member 2D
OR4M1 olfactory receptor, family 4, subfamily M, member 1
OR4N4 olfactory receptor, family 4, subfamily N, member 4
OR4Q3 olfactory receptor, family 4, subfamily Q, member 3
OR52B6 olfactory receptor, family 52, subfamily B, member 6
PARD3B par-3 family cell polarity regulator beta
PATE1 prostate and testis expressed 1
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCBP3 poly(rC) binding protein 3
PCDHA11 protocadherin alpha 11
PCDHA7 protocadherin alpha 7
PCDHB15 protocadherin beta 15
PCDHB3 protocadherin beta 3
PCDHB4 protocadherin beta 4
PCDHB8 protocadherin beta 8
PCDHGA1 protocadherin gamma subfamily A, 1
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDCL phosducin-like
PDZRN4 PDZ domain containing ring finger 4
PEA15 phosphoprotein enriched in astrocytes 15
PELP1 proline, glutamate and leucine rich protein 1
PEX26 peroxisomal biogenesis factor 26
PHF2 PHD finger protein 2
PHF21B PHD finger protein 21B
PHLDA1 pleckstrin homology-like domain, family A, member 1
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLK5 polo-like kinase 5
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POM121L4P POM121 transmembrane nucleoporin-like 4 pseudogene
PPAN-P2RY11 PPAN-P2RY11 readthrough
PRO0628 uncharacterized LOC29053
PRR22 proline rich 22
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTGR2 prostaglandin reductase 2
PTMS parathymosin
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PURA purine-rich element binding protein A
RAB19 RAB19, member RAS oncogene family
RASGEF1C RasGEF domain family, member 1C
RBM4B RNA binding motif protein 4B
RBMXL3 RNA binding motif protein, X-linked-like 3
RGMB repulsive guidance molecule family member b
RGR retinal G protein coupled receptor
RNF165 ring finger protein 165
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL13AP17 ribosomal protein L13a pseudogene 17
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPTN repetin
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAMD1 sterile alpha motif domain containing 1
SAMD5 sterile alpha motif domain containing 5
SAMD7 sterile alpha motif domain containing 7
SCARNA9L small Cajal body-specific RNA 9-like
SCGB3A1 secretoglobin, family 3A, member 1
SCRT2 scratch family zinc finger 2
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEPT3 septin 3
SETD1A SET domain containing 1A
SETD1B SET domain containing 1B
SEZ6L seizure related 6 homolog (mouse)-like
SF1 splicing factor 1
SF3A2 splicing factor 3a, subunit 2, 66kDa
SHF Src homology 2 domain containing F
SLC22A20 solute carrier family 22, member 20
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC36A3 solute carrier family 36, member 3
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMG6 SMG6 nonsense mediated mRNA decay factor
SMIM21 small integral membrane protein 21
SMOC1 SPARC related modular calcium binding 1
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SNORA11D small nucleolar RNA, H/ACA box 11D
SNORA71C small nucleolar RNA, H/ACA box 71C
SNORD116-4 small nucleolar RNA, C/D box 116-4
SNX15 sorting nexin 15
SOBP sine oculis binding protein homolog (Drosophila)
SOGA3 SOGA family member 3
SORBS3 sorbin and SH3 domain containing 3
SOX12 SRY (sex determining region Y)-box 12
SOX15 SRY (sex determining region Y)-box 15
SOX21 SRY (sex determining region Y)-box 21
SOX4 SRY (sex determining region Y)-box 4
SP2 Sp2 transcription factor
SPACA4 sperm acrosome associated 4
SPDYE7P speedy/RINGO cell cycle regulator family member E7, pseudogene
SPHKAP SPHK1 interactor, AKAP domain containing
SPIN3 spindlin family, member 3
SPRR2G small proline-rich protein 2G
SRCAP Snf2-related CREBBP activator protein
SREBF2 sterol regulatory element binding transcription factor 2
SSTR1 somatostatin receptor 1
SYCE1 synaptonemal complex central element protein 1
SYNE2 spectrin repeat containing, nuclear envelope 2
SYNE3 spectrin repeat containing, nuclear envelope family member 3
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TAL2 T-cell acute lymphocytic leukemia 2
TAS2R19 taste receptor, type 2, member 19
TAS2R31 taste receptor, type 2, member 31
TAS2R40 taste receptor, type 2, member 40
TCEAL1 transcription elongation factor A (SII)-like 1
TCEAL2 transcription elongation factor A (SII)-like 2
TCEAL3 transcription elongation factor A (SII)-like 3
TCEAL4 transcription elongation factor A (SII)-like 4
TCEAL5 transcription elongation factor A (SII)-like 5
TCF20 transcription factor 20 (AR1)
TEDDM1 transmembrane epididymal protein 1
TEX35 testis expressed 35
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM108 transmembrane protein 108
TMEM179 transmembrane protein 179
TMPRSS11B transmembrane protease, serine 11B
TNRC6B trinucleotide repeat containing 6B
TOX thymocyte selection-associated high mobility group box
TOX2 TOX high mobility group box family member 2
TRIM41 tripartite motif containing 41
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPM5 transient receptor potential cation channel, subfamily M, member 5
TSGA13 testis specific, 13
TSPAN32 tetraspanin 32
TSPY26P testis specific protein, Y-linked 26, pseudogene
TSSK4 testis-specific serine kinase 4
TTLL12 tubulin tyrosine ligase-like family member 12
UBQLN4 ubiquilin 4
UBTF upstream binding transcription factor, RNA polymerase I
USP17L2 ubiquitin specific peptidase 17-like family member 2
VGLL1 vestigial-like family member 1
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
WFDC10B WAP four-disulfide core domain 10B
WISP3 WNT1 inducible signaling pathway protein 3
WNT3 wingless-type MMTV integration site family, member 3
WNT7B wingless-type MMTV integration site family, member 7B
WNT9A wingless-type MMTV integration site family, member 9A
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XKR7 XK, Kell blood group complex subunit-related family, member 7
YLPM1 YLP motif containing 1
ZAN zonadhesin (gene/pseudogene)
ZC3H7B zinc finger CCCH-type containing 7B
ZDHHC22 zinc finger, DHHC-type containing 22
ZEB2 zinc finger E-box binding homeobox 2
ZFR2 zinc finger RNA binding protein 2
ZKSCAN7 zinc finger with KRAB and SCAN domains 7
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF213 zinc finger protein 213
ZNF454 zinc finger protein 454
ZNF513 zinc finger protein 513
ZNF534 zinc finger protein 534
ZNF646 zinc finger protein 646
ZNF70 zinc finger protein 70
ZNF74 zinc finger protein 74
ZSCAN10 zinc finger and SCAN domain containing 10
ZSCAN2 zinc finger and SCAN domain containing 2
ZSCAN5B zinc finger and SCAN domain containing 5B

low expression

Symbol Name
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
CDC16 cell division cycle 16
COPS4 COP9 signalosome subunit 4
ESD esterase D
FAM127B family with sequence similarity 127, member B
INTS12 integrator complex subunit 12
IPO5 importin 5
KPNA3 karyopherin alpha 3 (importin alpha 4)
MED4 mediator complex subunit 4
MICU2 mitochondrial calcium uptake 2
MIPEP mitochondrial intermediate peptidase
PCID2 PCI domain containing 2
SPG20 spastic paraplegia 20 (Troyer syndrome)
TGDS TDP-glucose 4,6-dehydratase
UBAC2 UBA domain containing 2
WBP4 WW domain binding protein 4
ZMYM5 zinc finger, MYM-type 5