Brain Lower Grade Glioma_LGG_TCGA-QH-A6X3-01A-21R-A32Q-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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328 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-QH-A6X3-01A-21R-A32Q-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AARS alanyl-tRNA synthetase
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACTL7A actin-like 7A
ADAMDEC1 ADAM-like, decysin 1
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AFF3 AF4/FMR2 family, member 3
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
AMICA1 adhesion molecule, interacts with CXADR antigen 1
ANKRD46 ankyrin repeat domain 46
APOLD1 apolipoprotein L domain containing 1
AQP7P1 aquaporin 7 pseudogene 1
AQP7P3 aquaporin 7 pseudogene 3
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARID5B AT rich interactive domain 5B (MRF1-like)
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BRWD1 bromodomain and WD repeat domain containing 1
BTG2 BTG family, member 2
C15ORF40 chromosome 15 open reading frame 40
C17ORF104 chromosome 17 open reading frame 104
C2ORF88 chromosome 2 open reading frame 88
C3ORF30 chromosome 3 open reading frame 30
C4ORF17 chromosome 4 open reading frame 17
C4ORF29 chromosome 4 open reading frame 29
C7ORF60 chromosome 7 open reading frame 60
C7ORF72 chromosome 7 open reading frame 72
C9ORF131 chromosome 9 open reading frame 131
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CBWD1 COBW domain containing 1
CBWD5 COBW domain containing 5
CCDC183 coiled-coil domain containing 183
CCDC43 coiled-coil domain containing 43
CCL24 chemokine (C-C motif) ligand 24
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CD163L1 CD163 molecule-like 1
CD209 CD209 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDH17 cadherin 17, LI cadherin (liver-intestine)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CELA2B chymotrypsin-like elastase family, member 2B
CEP83 centrosomal protein 83kDa
CFAP97 cilia and flagella associated protein 97
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CHUK conserved helix-loop-helix ubiquitous kinase
CIART circadian associated repressor of transcription
CLEC10A C-type lectin domain family 10, member A
CLEC7A C-type lectin domain family 7, member A
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNBD2 cyclic nucleotide binding domain containing 2
COPG2 coatomer protein complex, subunit gamma 2
CPB1 carboxypeptidase B1 (tissue)
CPN1 carboxypeptidase N, polypeptide 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1
CXORF56 chromosome X open reading frame 56
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
DEFB134 defensin, beta 134
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLD dihydrolipoamide dehydrogenase
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNASE1L3 deoxyribonuclease I-like 3
DNTT DNA nucleotidylexotransferase
DPH6 diphthamine biosynthesis 6
DTWD2 DTW domain containing 2
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
E2F5 E2F transcription factor 5, p130-binding
EDNRB endothelin receptor type B
EFCAB5 EF-hand calcium binding domain 5
EIF3J eukaryotic translation initiation factor 3, subunit J
EMC2 ER membrane protein complex subunit 2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EVI5 ecotropic viral integration site 5
FAM136BP family with sequence similarity 136, member B, pseudogene
FAM200A family with sequence similarity 200, member A
FAM35A family with sequence similarity 35, member A
FAM35BP family with sequence similarity 35, member A pseudogene
FAM71B family with sequence similarity 71, member B
FCF1 FCF1 rRNA-processing protein
FGL2 fibrinogen-like 2
FIBIN fin bud initiation factor homolog (zebrafish)
FRMD5 FERM domain containing 5
FYTTD1 forty-two-three domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GCFC2 GC-rich sequence DNA-binding factor 2
GCLC glutamate-cysteine ligase, catalytic subunit
GCM2 glial cells missing homolog 2 (Drosophila)
GK2 glycerol kinase 2
GLUD2 glutamate dehydrogenase 2
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GOLGA6B golgin A6 family, member B
GOLGA6L10 golgin A6 family-like 10
GOLGA6L5P golgin A6 family-like 5, pseudogene
GOLGA6L9 golgin A6 family-like 9
GOLIM4 golgi integral membrane protein 4
GRXCR1 glutaredoxin, cysteine rich 1
GSPT1 G1 to S phase transition 1
HCAR2 hydroxycarboxylic acid receptor 2
HCAR3 hydroxycarboxylic acid receptor 3
HEATR5A HEAT repeat containing 5A
HEMGN hemogen
HES1 hes family bHLH transcription factor 1
HNRNPR heterogeneous nuclear ribonucleoprotein R
HSFY2 heat shock transcription factor, Y linked 2
HSPA9 heat shock 70kDa protein 9 (mortalin)
IARS isoleucyl-tRNA synthetase
IFRD1 interferon-related developmental regulator 1
IGFBP1 insulin-like growth factor binding protein 1
IL20RB interleukin 20 receptor beta
IL33 interleukin 33
INSL6 insulin-like 6
ITGB7 integrin, beta 7
IVNS1ABP influenza virus NS1A binding protein
JADE1 jade family PHD finger 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM7A lysine (K)-specific demethylase 7A
KGFLP2 keratinocyte growth factor-like protein 2
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA1549 KIAA1549
KITLG KIT ligand
KLF9 Kruppel-like factor 9
KLHDC1 kelch domain containing 1
LARP1B La ribonucleoprotein domain family, member 1B
LARS leucyl-tRNA synthetase
LENEP lens epithelial protein
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LIMCH1 LIM and calponin homology domains 1
LINC00029 long intergenic non-protein coding RNA 29
LINC00161 long intergenic non-protein coding RNA 161
LINC00474 long intergenic non-protein coding RNA 474
LINC00593 long intergenic non-protein coding RNA 593
LINC01553 long intergenic non-protein coding RNA 1553
LOC100134868 uncharacterized LOC100134868
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2
LRRC70 leucine rich repeat containing 70
LUC7L2 LUC7-like 2 (S. cerevisiae)
LUZP6 leucine zipper protein 6
LYPLAL1 lysophospholipase-like 1
LYZ lysozyme
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAPK6 mitogen-activated protein kinase 6
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MARCH5 membrane-associated ring finger (C3HC4) 5
MAT2A methionine adenosyltransferase II, alpha
MCL1 myeloid cell leukemia 1
METTL2B methyltransferase like 2B
MIER3 mesoderm induction early response 1, family member 3
MOB4 MOB family member 4, phocein
MPEG1 macrophage expressed 1
MRC1 mannose receptor, C type 1
MRPL19 mitochondrial ribosomal protein L19
MRPL39 mitochondrial ribosomal protein L39
MRPL42P5 mitochondrial ribosomal protein L42 pseudogene 5
MTAP methylthioadenosine phosphorylase
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYEF2 myelin expression factor 2
NADK2 NAD kinase 2, mitochondrial
NAE1 NEDD8 activating enzyme E1 subunit 1
NBN nibrin
NBPF14 neuroblastoma breakpoint family, member 14
NBPF15 neuroblastoma breakpoint family, member 15
NCK1 NCK adaptor protein 1
NCKAP1 NCK-associated protein 1
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
NIN ninein (GSK3B interacting protein)
NOM1 nucleolar protein with MIF4G domain 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NSRP1 nuclear speckle splicing regulatory protein 1
NT5DC3 5'-nucleotidase domain containing 3
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
OR1I1 olfactory receptor, family 1, subfamily I, member 1
OR1N2 olfactory receptor, family 1, subfamily N, member 2
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4
OR4S1 olfactory receptor, family 4, subfamily S, member 1
OR52D1 olfactory receptor, family 52, subfamily D, member 1
OR52I2 olfactory receptor, family 52, subfamily I, member 2
OSBPL11 oxysterol binding protein-like 11
OSGIN2 oxidative stress induced growth inhibitor family member 2
OTUD6B OTU domain containing 6B
OTULIN OTU deubiquitinase with linear linkage specificity
OXNAD1 oxidoreductase NAD-binding domain containing 1
PARD3B par-3 family cell polarity regulator beta
PCDHB17P protocadherin beta 17 pseudogene
PCGF6 polycomb group ring finger 6
PDCD2L programmed cell death 2-like
PDCD7 programmed cell death 7
PDE8A phosphodiesterase 8A
PER3 period circadian clock 3
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHF10 PHD finger protein 10
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLRG1 pleiotropic regulator 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PMPCB peptidase (mitochondrial processing) beta
PNPLA8 patatin-like phospholipase domain containing 8
POT1 protection of telomeres 1
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPP1R3E protein phosphatase 1, regulatory subunit 3E
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKD1 protein kinase D1
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRMT9 protein arginine methyltransferase 9
PRO0628 uncharacterized LOC29053
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PRSS37 protease, serine, 37
PRSS41 protease, serine, 41
PSAT1 phosphoserine aminotransferase 1
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTGR2 prostaglandin reductase 2
PUS7 pseudouridylate synthase 7 (putative)
QKI QKI, KH domain containing, RNA binding
RAB12 RAB12, member RAS oncogene family
RBM28 RNA binding motif protein 28
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RET ret proto-oncogene
RFXAP regulatory factor X-associated protein
RINT1 RAD50 interactor 1
RIPPLY1 ripply transcriptional repressor 1
RNF182 ring finger protein 182
RNF39 ring finger protein 39
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
RPE65 retinal pigment epithelium-specific protein 65kDa
RPS15AP10 ribosomal protein S15a pseudogene 10
RRAGD Ras-related GTP binding D
SAMD13 sterile alpha motif domain containing 13
SCARNA9 small Cajal body-specific RNA 9
SCARNA9L small Cajal body-specific RNA 9-like
SCGB2B2 secretoglobin, family 2B, member 2
SCN7A sodium channel, voltage gated, type VII alpha subunit
SDHAF4 succinate dehydrogenase complex assembly factor 4
SDPR serum deprivation response
SENP6 SUMO1/sentrin specific peptidase 6
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC16A9 solute carrier family 16, member 9
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
SNORA25 small nucleolar RNA, H/ACA box 25
SNORA40 small nucleolar RNA, H/ACA box 40
SNORA8 small nucleolar RNA, H/ACA box 8
SNX31 sorting nexin 31
SPATA16 spermatogenesis associated 16
SPICE1 spindle and centriole associated protein 1
SPIRE1 spire-type actin nucleation factor 1
SRBD1 S1 RNA binding domain 1
STARD7 StAR-related lipid transfer (START) domain containing 7
STK17B serine/threonine kinase 17b
STRADB STE20-related kinase adaptor beta
TAAR8 trace amine associated receptor 8
TADA2A transcriptional adaptor 2A
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D15 TBC1 domain family, member 15
TCEA1 transcription elongation factor A (SII), 1
TDRP testis development related protein
THAP5 THAP domain containing 5
THOC2 THO complex 2
TIGD2 tigger transposable element derived 2
TIGD7 tigger transposable element derived 7
TLDC2 TBC/LysM-associated domain containing 2
TMEM100 transmembrane protein 100
TMEM128 transmembrane protein 128
TMEM64 transmembrane protein 64
TMEM65 transmembrane protein 65
TOB2 transducer of ERBB2, 2
TRAPPC13 trafficking protein particle complex 13
TRIM33 tripartite motif containing 33
TRIM40 tripartite motif containing 40
TRIM66 tripartite motif containing 66
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TSC22D1 TSC22 domain family, member 1
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPY1 testis specific protein, Y-linked 1
TTTY15 testis-specific transcript, Y-linked 15 (non-protein coding)
TUBE1 tubulin, epsilon 1
TYW5 tRNA-yW synthesizing protein 5
UBA2 ubiquitin-like modifier activating enzyme 2
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP50 ubiquitin specific peptidase 50
UTRN utrophin
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WASF3 WAS protein family, member 3
WASL Wiskott-Aldrich syndrome-like
WBP4 WW domain binding protein 4
WDR35 WD repeat domain 35
WEE2 WEE1 homolog 2 (S. pombe)
XPOT exportin, tRNA
ZAR1L zygote arrest 1-like
ZIC3 Zic family member 3
ZIC4 Zic family member 4
ZMYM5 zinc finger, MYM-type 5
ZNF146 zinc finger protein 146
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF330 zinc finger protein 330
ZNF33A zinc finger protein 33A
ZNF543 zinc finger protein 543
ZNF548 zinc finger protein 548
ZNF655 zinc finger protein 655
ZNF720 zinc finger protein 720
ZNF721 zinc finger protein 721
ZNF770 zinc finger protein 770
ZNF773 zinc finger protein 773
ZNF804A zinc finger protein 804A
ZNHIT6 zinc finger, HIT-type containing 6
ZSCAN25 zinc finger and SCAN domain containing 25
ZSCAN29 zinc finger and SCAN domain containing 29

low expression

Symbol Name
COPS7B COP9 signalosome subunit 7B
DIS3L2 DIS3 like 3'-5' exoribonuclease 2
EIF4E2 eukaryotic translation initiation factor 4E family member 2
HDLBP high density lipoprotein binding protein
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
NEK9 NIMA-related kinase 9
PTPMT1 protein tyrosine phosphatase, mitochondrial 1
STK25 serine/threonine kinase 25
THAP4 THAP domain containing 4
TMCO6 transmembrane and coiled-coil domains 6
UBE2F ubiquitin-conjugating enzyme E2F (putative)