Brain Lower Grade Glioma_LGG_TCGA-S9-A7R4-01A-12R-A34R-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Brain Lower Grade Glioma_LGG (The Cancer Genome Atlas)
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306 genes with high or low expression in Brain Lower Grade Glioma_LGG_TCGA-S9-A7R4-01A-12R-A34R-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABLIM3 actin binding LIM protein family, member 3
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACSL5 acyl-CoA synthetase long-chain family member 5
ACVR1 activin A receptor, type I
ACVRL1 activin A receptor type II-like 1
ADAT2 adenosine deaminase, tRNA-specific 2
ADCY4 adenylate cyclase 4
ADGRA2 adhesion G protein-coupled receptor A2
ADGRF5 adhesion G protein-coupled receptor F5
ADGRL4 adhesion G protein-coupled receptor L4
AGAP11 ankyrin repeat and GTPase domain Arf GTPase activating protein 11
AGFG1 ArfGAP with FG repeats 1
ALPL alkaline phosphatase, liver/bone/kidney
ANGPTL3 angiopoietin-like 3
APOLD1 apolipoprotein L domain containing 1
AQP7 aquaporin 7
ARHGAP27 Rho GTPase activating protein 27
ART1 ADP-ribosyltransferase 1
ATAD2B ATPase family, AAA domain containing 2B
ATP10A ATPase, class V, type 10A
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BOLL boule-like RNA-binding protein
BRD7P3 bromodomain containing 7 pseudogene 3
C1ORF68 chromosome 1 open reading frame 68
C1QTNF7 C1q and tumor necrosis factor related protein 7
C7ORF66 chromosome 7 open reading frame 66
C7ORF71 chromosome 7 open reading frame 71
CADM2 cell adhesion molecule 2
CAPNS2 calpain, small subunit 2
CASP12 caspase 12 (gene/pseudogene)
CASS4 Cas scaffolding protein family member 4
CC2D2B coiled-coil and C2 domain containing 2B
CCL3 chemokine (C-C motif) ligand 3
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCL4 chemokine (C-C motif) ligand 4
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCM2L cerebral cavernous malformation 2-like
CD2AP CD2-associated protein
CD34 CD34 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CH25H cholesterol 25-hydroxylase
CLDN25 claudin 25
CLDN5 claudin 5
CLEC14A C-type lectin domain family 14, member A
CLEC1A C-type lectin domain family 1, member A
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CMTM8 CKLF-like MARVEL transmembrane domain containing 8
CNOT6L CCR4-NOT transcription complex, subunit 6-like
COBLL1 cordon-bleu WH2 repeat protein-like 1
COLEC10 collectin sub-family member 10 (C-type lectin)
CXORF21 chromosome X open reading frame 21
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYSLTR2 cysteinyl leukotriene receptor 2
CYYR1 cysteine/tyrosine-rich 1
DDR2 discoidin domain receptor tyrosine kinase 2
DEFB109P1B defensin, beta 109, pseudogene 1B
DENND2C DENN/MADD domain containing 2C
DPH6 diphthamine biosynthesis 6
DPPA5 developmental pluripotency associated 5
EDN1 endothelin 1
EDN3 endothelin 3
EGFL8 EGF-like-domain, multiple 8
ELOVL7 ELOVL fatty acid elongase 7
EMCN endomucin
ENG endoglin
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPAS1 endothelial PAS domain protein 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESYT2 extended synaptotagmin-like protein 2
FAM160B1 family with sequence similarity 160, member B1
FAM228A family with sequence similarity 228, member A
FCAR Fc fragment of IgA receptor
FGD5 FYVE, RhoGEF and PH domain containing 5
FGD6 FYVE, RhoGEF and PH domain containing 6
FHL5 four and a half LIM domains 5
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT1 fms-related tyrosine kinase 1
FOXL2NB FOXL2 neighbor
FRY furry homolog (Drosophila)
FZD4 frizzled class receptor 4
GAB2 GRB2-associated binding protein 2
GLIS1 GLIS family zinc finger 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GOLGA6D golgin A6 family, member D
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
GTPBP2 GTP binding protein 2
GUSBP1 glucuronidase, beta pseudogene 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HES4 hes family bHLH transcription factor 4
HOOK3 hook microtubule-tethering protein 3
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HRC histidine rich calcium binding protein
HSPA12B heat shock 70kD protein 12B
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HYAL2 hyaluronoglucosaminidase 2
HYAL4 hyaluronoglucosaminidase 4
IGF2BP2-AS1 IGF2BP2 antisense RNA 1
INSL6 insulin-like 6
IRAK3 interleukin-1 receptor-associated kinase 3
ITGA1 integrin, alpha 1
ITGA10 integrin, alpha 10
ITGA11 integrin, alpha 11
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
ITM2A integral membrane protein 2A
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein
IYD iodotyrosine deiodinase
JMJD1C jumonji domain containing 1C
KCNK16 potassium channel, two pore domain subfamily K, member 16
KDM4E lysine (K)-specific demethylase 4E
KDR kinase insert domain receptor
KIAA1462 KIAA1462
KLF2 Kruppel-like factor 2
KLK9 kallikrein-related peptidase 9
KRT25 keratin 25, type I
KRT39 keratin 39, type I
KRT76 keratin 76, type II
KRTAP10-7 keratin associated protein 10-7
LAMA3 laminin, alpha 3
LCORL ligand dependent nuclear receptor corepressor-like
LEPR leptin receptor
LINC00235 long intergenic non-protein coding RNA 235
LMOD3 leiomodin 3 (fetal)
LOC100129055 cyclin Y-like 1 pseudogene
LOC285074 anaphase promoting complex subunit 1 pseudogene
LOC400927 TPTE and PTEN homologous inositol lipid phosphatase pseudogene
LOC440461 Rho GTPase activating protein 27 pseudogene
LOC646762 uncharacterized LOC646762
LOC90784 uncharacterized LOC90784
LRRC36 leucine rich repeat containing 36
LRRC70 leucine rich repeat containing 70
LRRC8C leucine rich repeat containing 8 family, member C
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAGEA12 melanoma antigen family A12
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
MBD3L5 methyl-CpG binding domain protein 3-like 5
MEP1B meprin A, beta
MMRN2 multimerin 2
MROH9 maestro heat-like repeat family member 9
MTMR9LP myotubularin related protein 9-like, pseudogene
MYCT1 myc target 1
MYO1B myosin IB
N4BP2L2 NEDD4 binding protein 2-like 2
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NET1 neuroepithelial cell transforming 1
NKX6-3 NK6 homeobox 3
NLRP1 NLR family, pyrin domain containing 1
NLRP14 NLR family, pyrin domain containing 14
NLRP3 NLR family, pyrin domain containing 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NOSTRIN nitric oxide synthase trafficking
NOTCH3 notch 3
NOTCH4 notch 4
OCLM oculomedin
OCLN occludin
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR3A4P olfactory receptor, family 3, subfamily A, member 4 pseudogene
OR4D1 olfactory receptor, family 4, subfamily D, member 1
OR4F15 olfactory receptor, family 4, subfamily F, member 15
OR4X2 olfactory receptor, family 4, subfamily X, member 2 (gene/pseudogene)
OR52N1 olfactory receptor, family 52, subfamily N, member 1
OR52N5 olfactory receptor, family 52, subfamily N, member 5
OR56A3 olfactory receptor, family 56, subfamily A, member 3
OR6C70 olfactory receptor, family 6, subfamily C, member 70
OR6F1 olfactory receptor, family 6, subfamily F, member 1
OR6X1 olfactory receptor, family 6, subfamily X, member 1
OR8H1 olfactory receptor, family 8, subfamily H, member 1
OTUD1 OTU deubiquitinase 1
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PANX3 pannexin 3
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAX4 paired box 4
PCDHB3 protocadherin beta 3
PCDHGB6 protocadherin gamma subfamily B, 6
PDE5A phosphodiesterase 5A, cGMP-specific
PDGFC platelet derived growth factor C
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PEAR1 platelet endothelial aggregation receptor 1
PIAS3 protein inhibitor of activated STAT, 3
PKDREJ polycystin (PKD) family receptor for egg jelly
PLA2G12B phospholipase A2, group XIIB
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PODXL podocalyxin-like
PRAMEF4 PRAME family member 4
PRDM1 PR domain containing 1, with ZNF domain
PRG1 p53-responsive gene 1
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKCH protein kinase C, eta
PRKG2 protein kinase, cGMP-dependent, type II
PRR5-ARHGAP8 PRR5-ARHGAP8 readthrough
PSG6 pregnancy specific beta-1-glycoprotein 6
PTCD3 pentatricopeptide repeat domain 3
PXT1 peroxisomal, testis specific 1
RABGGTB Rab geranylgeranyltransferase, beta subunit
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RBM20 RNA binding motif protein 20
RBMS2 RNA binding motif, single stranded interacting protein 2
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RHOBTB1 Rho-related BTB domain containing 1
RNF39 ring finger protein 39
RNPC3 RNA-binding region (RNP1, RRM) containing 3
RP1 retinitis pigmentosa 1 (autosomal dominant)
RUNDC3B RUN domain containing 3B
SAA3P serum amyloid A3 pseudogene
SCARF1 scavenger receptor class F, member 1
SCGB1C1 secretoglobin, family 1C, member 1
SDPR serum deprivation response
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEPT7P9 septin 7 pseudogene 9
SFTPA2 surfactant protein A2
SGK1 serum/glucocorticoid regulated kinase 1
SHE Src homology 2 domain containing E
SIX4 SIX homeobox 4
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC35D3 solute carrier family 35, member D3
SLC38A11 solute carrier family 38, member 11
SLC39A10 solute carrier family 39 (zinc transporter), member 10
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A5P2 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLFN5 schlafen family member 5
SLIT3 slit homolog 3 (Drosophila)
SMAD6 SMAD family member 6
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SNORA21 small nucleolar RNA, H/ACA box 21
SNORA25 small nucleolar RNA, H/ACA box 25
SNORA31 small nucleolar RNA, H/ACA box 31
SNORA40 small nucleolar RNA, H/ACA box 40
SNORA71A small nucleolar RNA, H/ACA box 71A
SNORA8 small nucleolar RNA, H/ACA box 8
SNORD115-7 small nucleolar RNA, C/D box 115-7
SOX17 SRY (sex determining region Y)-box 17
SPACA1 sperm acrosome associated 1
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STARD8 StAR-related lipid transfer (START) domain containing 8
STRN3 striatin, calmodulin binding protein 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYNJ2BP synaptojanin 2 binding protein
TAL1 T-cell acute lymphocytic leukemia 1
TARP TCR gamma alternate reading frame protein
TAS1R2 taste receptor, type 1, member 2
TBC1D4 TBC1 domain family, member 4
TBX18 T-box 18
TDRD10 tudor domain containing 10
TEK TEK tyrosine kinase, endothelial
TEX36 testis expressed 36
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TM4SF18 transmembrane 4 L six family member 18
TMC4 transmembrane channel-like 4
TMEM204 transmembrane protein 204
TMEM213 transmembrane protein 213
TMEM236 transmembrane protein 236
TMPRSS11B transmembrane protease, serine 11B
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNNI3K TNNI3 interacting kinase
TOPAZ1 testis and ovary specific PAZ domain containing 1
TRAPPC3L trafficking protein particle complex 3-like
TRIB3 tribbles pseudokinase 3
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TSNAX-DISC1 TSNAX-DISC1 readthrough (NMD candidate)
TTC36 tetratricopeptide repeat domain 36
TTTY4C testis-specific transcript, Y-linked 4C (non-protein coding)
TUBAL3 tubulin, alpha-like 3
UBE2Q2P1 ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 1
UBL4B ubiquitin-like 4B
USP17L6P ubiquitin specific peptidase 17-like family member 6, pseudogene
USP53 ubiquitin specific peptidase 53
UTRN utrophin
VWA2 von Willebrand factor A domain containing 2
WDFY1 WD repeat and FYVE domain containing 1
WDR88 WD repeat domain 88
ZFP62 ZFP62 zinc finger protein
ZNF189 zinc finger protein 189
ZNF224 zinc finger protein 224
ZNF284 zinc finger protein 284
ZNF366 zinc finger protein 366
ZNF460 zinc finger protein 460
ZNF543 zinc finger protein 543
ZNF551 zinc finger protein 551
ZNF587 zinc finger protein 587
ZNF749 zinc finger protein 749
ZNF77 zinc finger protein 77
ZNF772 zinc finger protein 772
ZNF804A zinc finger protein 804A
ZNF836 zinc finger protein 836
ZSCAN5B zinc finger and SCAN domain containing 5B

low expression

Symbol Name
ARFIP2 ADP-ribosylation factor interacting protein 2
RIC8A RIC8 guanine nucleotide exchange factor A
SLC25A38 solute carrier family 25, member 38