Brain Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description 1: The portion of the vertebrate central nervous system that constitutes the organ of thought and neural coordination, includes all the higher nervous centers receiving stimuli from the sense organs and interpreting and correlating them to formulate the motor impulses, is made up of neurons and supporting and nutritive structures, is enclosed within the skull, and is continuous with the spinal cord through the foramen magnum. Also named encephalon. 2: A nervous center in invertebrates comparable in position and function to the vertebrate brain. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000142)
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Genes

34 genes associated with the trait Brain in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
ST5 suppression of tumorigenicity 5 1.57236
KANSL1 KAT8 regulatory NSL complex subunit 1 1.18308
HMGA2 high mobility group AT-hook 2 0.907793
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 0.880282
SBNO1 strawberry notch homolog 1 (Drosophila) 0.774665
DNAH11 dynein, axonemal, heavy chain 11 0.70655
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.700916
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.673162
EMC1 ER membrane protein complex subunit 1 0.64828
FGF14 fibroblast growth factor 14 0.577207
FRMD6 FERM domain containing 6 0.552134
SHB Src homology 2 domain containing adaptor protein B 0.539181
CADPS2 Ca++-dependent secretion activator 2 0.539181
BOK BCL2-related ovarian killer 0.539181
YAP1 Yes-associated protein 1 0.538962
GLYATL3 glycine-N-acyltransferase-like 3 0.518003
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 0.514313
VLDLR-AS1 VLDLR antisense RNA 1 0.50274
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.50084
CSMD2 CUB and Sushi multiple domains 2 0.50084
THSD7B thrombospondin, type I, domain containing 7B 0.480567
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.463462
KCNIP4 Kv channel interacting protein 4 0.452315
SNTG1 syntrophin, gamma 1 0.449993
WDR70 WD repeat domain 70 0.426262
NTN4 netrin 4 0.413157
SGCZ sarcoglycan, zeta 0.393289
SLIT1 slit homolog 1 (Drosophila) 0.372152
ELMO1 engulfment and cell motility 1 0.365574
CNTN5 contactin 5 0.33862
TNNI3K TNNI3 interacting kinase 0.283715
ULK4 unc-51 like kinase 4 0.17264
PTPRD protein tyrosine phosphatase, receptor type, D 0.168566
DENND4A DENN/MADD domain containing 4A 0.05875