Breast Adenocarcinoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A breast carcinoma that originates in the milk ducts and/or lobules (glandular tissue) of the breast. (Human Disease Ontology, DOID_3458)
External Link https://www.disgenet.org/browser/0/1/0/C0858252
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Genes

211 genes associated with the disease Breast Adenocarcinoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACTB actin, beta
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AGR2 anterior gradient 2
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALB albumin
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANXA5 annexin A5
AR androgen receptor
ARID1A AT rich interactive domain 1A (SWI-like)
ARID1B AT rich interactive domain 1B (SWI1-like)
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BECN1 beclin 1, autophagy related
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTC betacellulin
BTK Bruton agammaglobulinemia tyrosine kinase
CA8 carbonic anhydrase VIII
CADM1 cell adhesion molecule 1
CANX calnexin
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD68 CD68 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHEK2 checkpoint kinase 2
COX2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSRP1 cysteine and glycine-rich protein 1
CTSB cathepsin B
CXCL10 chemokine (C-X-C motif) ligand 10
CXCR3 chemokine (C-X-C motif) receptor 3
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDT D-dopachrome tautomerase
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
DHFR dihydrofolate reductase
DNLZ DNL-type zinc finger
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ELK1 ELK1, member of ETS oncogene family
EP300 E1A binding protein p300
EPCAM epithelial cell adhesion molecule
EPHA2 EPH receptor A2
EPHA3 EPH receptor A3
EPHB6 EPH receptor B6
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
FDXR ferredoxin reductase
FGF3 fibroblast growth factor 3
FGF4 fibroblast growth factor 4
FGFR1 fibroblast growth factor receptor 1
FLT1 fms-related tyrosine kinase 1
FMNL1 formin-like 1
FNBP1L formin binding protein 1-like
FOXA1 forkhead box A1
FST follistatin
G6PD glucose-6-phosphate dehydrogenase
GABARAPL1 GABA(A) receptor-associated protein like 1
GATA3 GATA binding protein 3
GCLC glutamate-cysteine ligase, catalytic subunit
GH1 growth hormone 1
GJA1 gap junction protein, alpha 1, 43kDa
GPX1 glutathione peroxidase 1
GRAP2 GRB2-related adaptor protein 2
H2AX H2A.X variant histone
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK2 hexokinase 2
HMGA2 high mobility group AT-hook 2
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPB1 heat shock 27kDa protein 1
IBSP integrin-binding sialoprotein
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IPO9 importin 9
IRF9 interferon regulatory factor 9
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KAT5 K(lysine) acetyltransferase 5
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KDM8 lysine (K)-specific demethylase 8
KDR kinase insert domain receptor
KLF4 Kruppel-like factor 4 (gut)
KLK3 kallikrein-related peptidase 3
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
LGALS1 lectin, galactoside-binding, soluble, 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LYNX1 Ly6/neurotoxin 1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MCL1 myeloid cell leukemia 1
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MELK maternal embryonic leucine zipper kinase
MFGE8 milk fat globule-EGF factor 8 protein
MINDY3 MINDY lysine 48 deubiquitinase 3
MME membrane metallo-endopeptidase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MSTN myostatin
MTA1 metastasis associated 1
MUC1 mucin 1, cell surface associated
MXI1 MAX interactor 1, dimerization protein
MZB1 marginal zone B and B1 cell-specific protein
NCOR1 nuclear receptor corepressor 1
NDRG1 N-myc downstream regulated 1
NFE2L2 nuclear factor, erythroid 2-like 2
NONO non-POU domain containing, octamer-binding
NOTCH1 notch 1
NOTCH2 notch 2
NPEPPS aminopeptidase puromycin sensitive
NQO1 NAD(P)H dehydrogenase, quinone 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NUCLEOLIN nucleolin multifunctional protein
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OPRM1 opioid receptor, mu 1
PAEP progestagen-associated endometrial protein
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PALB2 partner and localizer of BRCA2
PBRM1 polybromo 1
PCNA proliferating cell nuclear antigen
PDLIM4 PDZ and LIM domain 4
PDLIM7 PDZ and LIM domain 7 (enigma)
PDPK1 3-phosphoinositide dependent protein kinase 1
PGRMC1 progesterone receptor membrane component 1
PGRMC2 progesterone receptor membrane component 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLAG1 pleiomorphic adenoma gene 1
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POU1F1 POU class 1 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PRL prolactin
PROS1 protein S (alpha)
PSAT1 phosphoserine aminotransferase 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PXN paxillin
RAG1 recombination activating gene 1
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RB1 retinoblastoma 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SEPP1 selenoprotein P, plasma, 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC12A9 solute carrier family 12, member 9
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBL1X transducin (beta)-like 1X-linked
TBL1Y transducin (beta)-like 1, Y-linked
TBX3 T-box 3
TFF1 trefoil factor 1
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TJP1 tight junction protein 1
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TXNIP thioredoxin interacting protein
UGCG UDP-glucose ceramide glucosyltransferase
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WASF3 WAS protein family, member 3
WISP2 WNT1 inducible signaling pathway protein 2
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase