Breast Cancer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A thoracic cancer that originates in the mammary gland. (Human Disease Ontology, DOID_1612)
External Link https://www.disgenet.org/browser/0/1/0/C1854365
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Genes

67 genes associated with the disease Breast Cancer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADAM11 ADAM metallopeptidase domain 11
ADAM9 ADAM metallopeptidase domain 9
ANXA1 annexin A1
APC adenomatous polyposis coli
APOC3 apolipoprotein C-III
BCL2 B-cell CLL/lymphoma 2
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
CALD1 caldesmon 1
CCL5 chemokine (C-C motif) ligand 5
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHEK2 checkpoint kinase 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CNTN6 contactin 6
COX2
CSF3 colony stimulating factor 3 (granulocyte)
CTNND2 catenin (cadherin-associated protein), delta 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DACH1 dachshund family transcription factor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNER delta/notch-like EGF repeat containing
EDIL3 EGF-like repeats and discoidin I-like domains 3
EDN1 endothelin 1
EGFR epidermal growth factor receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
FGF17 fibroblast growth factor 17
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR4 fibroblast growth factor receptor 4
FHIT fragile histidine triad
HMGA1 high mobility group AT-hook 1
HOXB13 homeobox B13
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL10 interleukin 10
IL17RB interleukin 17 receptor B
IL6R interleukin 6 receptor
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
NCOR2 nuclear receptor corepressor 2
NEU1 sialidase 1 (lysosomal sialidase)
NEURL1 neuralized E3 ubiquitin protein ligase 1
PAWR PRKC, apoptosis, WT1, regulator
PGR progesterone receptor
PGRMC2 progesterone receptor membrane component 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PSAP prosaposin
PSAT1 phosphoserine aminotransferase 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPP1 secreted phosphoprotein 1
TARBP2 TAR (HIV-1) RNA binding protein 2
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TSC22D1 TSC22 domain family, member 1
VTCN1 V-set domain containing T cell activation inhibitor 1
VWF von Willebrand factor
ZNF35 zinc finger protein 35