Breast Cancer_Mammary gland_GSE2528 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2528
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Genes

600 genes differentially expressed during Breast Cancer_Mammary gland_GSE2528 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
BAG2 BCL2-associated athanogene 2 3.82233
SERP1 stress-associated endoplasmic reticulum protein 1 3.68689
RAB18 RAB18, member RAS oncogene family 3.66567
ACSL4 acyl-CoA synthetase long-chain family member 4 3.5411
PTDSS1 phosphatidylserine synthase 1 3.45295
DAP death-associated protein 3.37832
PELI1 pellino E3 ubiquitin protein ligase 1 3.29667
TSPAN8 tetraspanin 8 3.22926
RHOA ras homolog family member A 3.0262
VBP1 von Hippel-Lindau binding protein 1 3.01748
ACTN4 actinin, alpha 4 3.00846
ETV1 ets variant 1 2.92558
ESD esterase D 2.86001
PQLC1 PQ loop repeat containing 1 2.85608
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.85586
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 2.8442
WSB2 WD repeat and SOCS box containing 2 2.78372
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 2.7718
MYDGF myeloid-derived growth factor 2.76402
CD9 CD9 molecule 2.71394
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 2.70156
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 2.63994
CAST calpastatin 2.6348
MRPL44 mitochondrial ribosomal protein L44 2.63125
CLCN4 chloride channel, voltage-sensitive 4 2.57562
EZR ezrin 2.57422
CECR6 cat eye syndrome chromosome region, candidate 6 2.57001
RIC8A RIC8 guanine nucleotide exchange factor A 2.56234
FNDC3A fibronectin type III domain containing 3A 2.51824
VTA1 vesicle (multivesicular body) trafficking 1 2.51651
PERP PERP, TP53 apoptosis effector 2.46298
DSC2 desmocollin 2 2.4599
TBC1D23 TBC1 domain family, member 23 2.43828
UBXN4 UBX domain protein 4 2.43697
PUF60 poly-U binding splicing factor 60KDa 2.42544
PRADC1 protease-associated domain containing 1 2.38968
ZDHHC5 zinc finger, DHHC-type containing 5 2.37129
HAT1 histone acetyltransferase 1 2.3427
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 2.33912
ALDOC aldolase C, fructose-bisphosphate 2.32454
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 2.27631
PRELID1 PRELI domain containing 1 2.27614
SOCS2 suppressor of cytokine signaling 2 2.26537
CLDN7 claudin 7 2.25043
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.24789
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 2.2407
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 2.23209
RCN2 reticulocalbin 2, EF-hand calcium binding domain 2.23154
EFS embryonal Fyn-associated substrate 2.22103
GPN3 GPN-loop GTPase 3 2.21102
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 2.20881
UFC1 ubiquitin-fold modifier conjugating enzyme 1 2.20414
EPCAM epithelial cell adhesion molecule 2.20244
CRELD2 cysteine-rich with EGF-like domains 2 2.19694
XBP1 X-box binding protein 1 2.1953
CHMP3 charged multivesicular body protein 3 2.18149
GOLPH3 golgi phosphoprotein 3 (coat-protein) 2.17365
NDFIP1 Nedd4 family interacting protein 1 2.1395
SRP19 signal recognition particle 19kDa 2.13816
FXYD3 FXYD domain containing ion transport regulator 3 2.1326
IGBP1 immunoglobulin (CD79A) binding protein 1 2.12318
UNC119B unc-119 homolog B (C. elegans) 2.11741
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.11047
PRC1 protein regulator of cytokinesis 1 2.10186
EXOC7 exocyst complex component 7 2.09945
FAM83H family with sequence similarity 83, member H 2.08638
RNASEH2B ribonuclease H2, subunit B 2.05766
TMED7 transmembrane emp24 protein transport domain containing 7 2.04914
DTNB dystrobrevin, beta 2.04041
BIRC5 baculoviral IAP repeat containing 5 2.03109
TUFT1 tuftelin 1 2.0233
F11R F11 receptor 2.0201
HAX1 HCLS1 associated protein X-1 2.01989
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 2.01641
DIAPH3 diaphanous-related formin 3 2.00413
PGK1 phosphoglycerate kinase 1 2.0003
AP2M1 adaptor-related protein complex 2, mu 1 subunit 1.9942
ARL1 ADP-ribosylation factor-like 1 1.97556
TM9SF1 transmembrane 9 superfamily member 1 1.97237
WWC1 WW and C2 domain containing 1 1.97117
ERCC2 excision repair cross-complementation group 2 1.96449
IER2 immediate early response 2 1.95441
MLH1 mutL homolog 1 1.94788
TPD52L1 tumor protein D52-like 1 1.94774
CDC42SE1 CDC42 small effector 1 1.94024
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 1.93248
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.92802
FUBP1 far upstream element (FUSE) binding protein 1 1.92515
TPD52 tumor protein D52 1.92226
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 1.92143
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 1.89981
FOLR1 folate receptor 1 (adult) 1.89903
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.89392
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 1.89354
MED20 mediator complex subunit 20 1.891
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.89094
RHOD ras homolog family member D 1.88816
SERF2 small EDRK-rich factor 2 1.88403
LIMS1 LIM and senescent cell antigen-like domains 1 1.88382
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 1.87907
ZFAND5 zinc finger, AN1-type domain 5 1.87491
PDCD6 programmed cell death 6 1.86948
DLL1 delta-like 1 (Drosophila) 1.8694
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 1.8647
ATPIF1 ATPase inhibitory factor 1 1.8607
PDIA4 protein disulfide isomerase family A, member 4 1.85993
GANAB glucosidase, alpha; neutral AB 1.85709
IER3 immediate early response 3 1.85476
CNPY2 canopy FGF signaling regulator 2 1.84865
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 1.83889
IARS isoleucyl-tRNA synthetase 1.8286
CDC37 cell division cycle 37 1.82682
TBRG1 transforming growth factor beta regulator 1 1.82054
CXXC1 CXXC finger protein 1 1.81899
E2F5 E2F transcription factor 5, p130-binding 1.81674
SRSF9 serine/arginine-rich splicing factor 9 1.81634
PAIP2 poly(A) binding protein interacting protein 2 1.81466
PEX11B peroxisomal biogenesis factor 11 beta 1.80995
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 1.80802
F2RL1 coagulation factor II (thrombin) receptor-like 1 1.79447
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 1.78967
RPA1 replication protein A1, 70kDa 1.78662
SNW1 SNW domain containing 1 1.78486
ARL6 ADP-ribosylation factor-like 6 1.78407
ATXN7L3 ataxin 7-like 3 1.78253
MINPP1 multiple inositol-polyphosphate phosphatase 1 1.77962
ETNK1 ethanolamine kinase 1 1.77869
CLDN1 claudin 1 1.77137
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 1.76614
TM2D3 TM2 domain containing 3 1.75813
COL11A1 collagen, type XI, alpha 1 1.75271
CD81 CD81 molecule 1.74387
SRSF1 serine/arginine-rich splicing factor 1 1.74289
FAM134B family with sequence similarity 134, member B 1.73855
RNF149 ring finger protein 149 1.73535
CENPBD1 CENPB DNA-binding domains containing 1 1.72889
HSPA4 heat shock 70kDa protein 4 1.7286
B9D1 B9 protein domain 1 1.72828
TOM1L1 target of myb1 (chicken)-like 1 1.72614
LIG3 ligase III, DNA, ATP-dependent 1.71626
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 1.71502
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 1.71445
BTD biotinidase 1.71071
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.70919
RAB3IP RAB3A interacting protein 1.70691
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 1.70631
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 1.69281
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 1.67046
C11ORF58 chromosome 11 open reading frame 58 1.6696
AIM1 absent in melanoma 1 1.65789
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 1.6575
ZC3H11A zinc finger CCCH-type containing 11A 1.65562
FEN1 flap structure-specific endonuclease 1 1.65322
PTK2B protein tyrosine kinase 2 beta 1.65061
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 1.65007
SMAGP small cell adhesion glycoprotein 1.64412
EMG1 EMG1 N1-specific pseudouridine methyltransferase 1.64323
CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 1.64241
ARF4 ADP-ribosylation factor 4 1.6409
SAMD10 sterile alpha motif domain containing 10 1.63486
GLO1 glyoxalase I 1.6347
FBXW2 F-box and WD repeat domain containing 2 1.63321
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 1.6242
FRRS1 ferric-chelate reductase 1 1.6214
AMOT angiomotin 1.61911
SNX1 sorting nexin 1 1.61713
POMT1 protein-O-mannosyltransferase 1 1.61094
SPINT1 serine peptidase inhibitor, Kunitz type 1 1.59948
RCC1 regulator of chromosome condensation 1 1.59817
TGS1 trimethylguanosine synthase 1 1.59514
BAK1 BCL2-antagonist/killer 1 1.59438
RHOC ras homolog family member C 1.59155
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 1.59001
CYB561 cytochrome b561 1.58615
CHMP2B charged multivesicular body protein 2B 1.58594
NR2C1 nuclear receptor subfamily 2, group C, member 1 1.57915
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 1.5788
RAB14 RAB14, member RAS oncogene family 1.57547
SLC22A18 solute carrier family 22, member 18 1.57509
TMPO thymopoietin 1.57444
ZFYVE19 zinc finger, FYVE domain containing 19 1.56874
AASS aminoadipate-semialdehyde synthase 1.56141
RNF167 ring finger protein 167 1.55976
LITAF lipopolysaccharide-induced TNF factor 1.55923
MBTD1 mbt domain containing 1 1.55818
COPS6 COP9 signalosome subunit 6 1.55674
LBP lipopolysaccharide binding protein 1.54946
CINP cyclin-dependent kinase 2 interacting protein 1.54625
C6ORF62 chromosome 6 open reading frame 62 1.54081
ERO1L ERO1-like (S. cerevisiae) 1.53981
TAPBP TAP binding protein (tapasin) 1.53862
CAPN9 calpain 9 1.53715
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.52998
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.52846
C9ORF3 chromosome 9 open reading frame 3 1.52666
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 1.51734
SMYD5 SMYD family member 5 1.51628
CDK8 cyclin-dependent kinase 8 1.51431
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 1.51306
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.51261
TRIM11 tripartite motif containing 11 1.51159
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 1.50924
RABEP1 rabaptin, RAB GTPase binding effector protein 1 1.50918
WBP5 WW domain binding protein 5 1.50818
STXBP2 syntaxin binding protein 2 1.50732
ETV4 ets variant 4 1.50687
ACOT8 acyl-CoA thioesterase 8 1.49997
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 1.49501
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.49372
SPRYD4 SPRY domain containing 4 1.49354
CLDN3 claudin 3 1.49346
EML5 echinoderm microtubule associated protein like 5 1.48934
CCND1 cyclin D1 1.48906
ZFYVE16 zinc finger, FYVE domain containing 16 1.48832
ANKH ANKH inorganic pyrophosphate transport regulator 1.48117
HN1 hematological and neurological expressed 1 1.47711
GLOD4 glyoxalase domain containing 4 1.47644
CDC25C cell division cycle 25C 1.47564
METTL8 methyltransferase like 8 1.47494
JKAMP JNK1/MAPK8-associated membrane protein 1.46892
RSU1 Ras suppressor protein 1 1.4637
SND1 staphylococcal nuclease and tudor domain containing 1 1.46112
NTAN1 N-terminal asparagine amidase 1.45832
PKM pyruvate kinase, muscle 1.45801
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 1.45286
INPPL1 inositol polyphosphate phosphatase-like 1 1.45281
NPNT nephronectin 1.4511
CNOT4 CCR4-NOT transcription complex, subunit 4 1.45101
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 1.44826
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 1.44755
CTNND1 catenin (cadherin-associated protein), delta 1 1.44288
DHODH dihydroorotate dehydrogenase (quinone) 1.44249
HDLBP high density lipoprotein binding protein 1.44036
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.43786
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 1.43443
ZNF878 zinc finger protein 878 1.43264
GNA13 guanine nucleotide binding protein (G protein), alpha 13 1.43013
FAM96A family with sequence similarity 96, member A 1.42994
TMX1 thioredoxin-related transmembrane protein 1 1.4285
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.42731
STX7 syntaxin 7 1.4269
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 1.42545
TTC3 tetratricopeptide repeat domain 3 1.42489
TFCP2 transcription factor CP2 1.42462
TRIB3 tribbles pseudokinase 3 1.42406
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 1.42323
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.42167
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase 1.41924
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 1.41747
FAM114A2 family with sequence similarity 114, member A2 1.41587
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 1.4156
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.4112
PLD3 phospholipase D family, member 3 1.40753
BABAM1 BRISC and BRCA1 A complex member 1 1.40521
OCIAD1 OCIA domain containing 1 1.40354
PTGR1 prostaglandin reductase 1 1.39813
SEC62 SEC62 homolog (S. cerevisiae) 1.39547
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 1.3932
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 1.38691
RAB11A RAB11A, member RAS oncogene family 1.38538
ANKRD49 ankyrin repeat domain 49 1.37997
DCPS decapping enzyme, scavenger 1.37975
RPL7L1 ribosomal protein L7-like 1 1.37208
SEC11C SEC11 homolog C (S. cerevisiae) 1.37208
PDLIM1 PDZ and LIM domain 1 1.36938
CDK1 cyclin-dependent kinase 1 1.36871
PDCD2L programmed cell death 2-like 1.3673
KIAA1524 KIAA1524 1.36659
MTPN myotrophin 1.36196
DSG2 desmoglein 2 1.36191
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 1.36125
MAP3K3 mitogen-activated protein kinase kinase kinase 3 1.3589
RXRA retinoid X receptor, alpha 1.35885
MPG N-methylpurine-DNA glycosylase 1.35733
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 1.35672
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 1.35585
CNN3 calponin 3, acidic 1.35311
C1ORF174 chromosome 1 open reading frame 174 1.35251
EMID1 EMI domain containing 1 1.35196
MYO6 myosin VI 1.34899
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.34776
TRIM37 tripartite motif containing 37 1.34571
CTBP2 C-terminal binding protein 2 1.34564
ANXA4 annexin A4 1.33913
COL9A1 collagen, type IX, alpha 1 1.33841
RAB10 RAB10, member RAS oncogene family 1.33819
EMC3 ER membrane protein complex subunit 3 1.33814
CSNK1D casein kinase 1, delta 1.33786
BIK BCL2-interacting killer (apoptosis-inducing) 1.33749
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 1.33595
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 1.33194
MAT2B methionine adenosyltransferase II, beta 1.32955
MOB1B MOB kinase activator 1B 1.32721
IRF2BP1 interferon regulatory factor 2 binding protein 1 1.32386
ZFP62 ZFP62 zinc finger protein 1.32339
ANKRD17 ankyrin repeat domain 17 1.31904
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.3183
PRKCD protein kinase C, delta 1.31545
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1.31283
DHRSX dehydrogenase/reductase (SDR family) X-linked 1.31219

decreased expression

Symbol Name Standardized Value
MOCS2 molybdenum cofactor synthesis 2 -3.85823
CCND3 cyclin D3 -3.7111
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 -3.66095
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -3.57048
DDT D-dopachrome tautomerase -3.53199
PNPLA2 patatin-like phospholipase domain containing 2 -3.52004
GSTZ1 glutathione S-transferase zeta 1 -3.50695
CRAT carnitine O-acetyltransferase -3.49294
ZWINT ZW10 interacting kinetochore protein -3.4028
CDO1 cysteine dioxygenase type 1 -3.22086
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) -3.2009
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) -3.07272
ADIPOR2 adiponectin receptor 2 -2.98851
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase -2.9871
PGM1 phosphoglucomutase 1 -2.98524
MYO1C myosin IC -2.98182
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -2.9596
ELOVL6 ELOVL fatty acid elongase 6 -2.9167
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) -2.89804
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -2.865
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.78888
RAMP2 receptor (G protein-coupled) activity modifying protein 2 -2.77471
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -2.7704
RNF181 ring finger protein 181 -2.74114
CSDE1 cold shock domain containing E1, RNA-binding -2.73509
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -2.69881
CES1 carboxylesterase 1 -2.66163
RASA3 RAS p21 protein activator 3 -2.6531
NOS3 nitric oxide synthase 3 (endothelial cell) -2.62837
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -2.59928
GSN gelsolin -2.58465
SOX18 SRY (sex determining region Y)-box 18 -2.57117
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -2.57015
LPL lipoprotein lipase -2.56761
LAMP1 lysosomal-associated membrane protein 1 -2.51077
GREM2 gremlin 2, DAN family BMP antagonist -2.50499
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa -2.47523
MRPS17 mitochondrial ribosomal protein S17 -2.45676
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -2.45253
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -2.41276
VEGFB vascular endothelial growth factor B -2.41272
G6PD glucose-6-phosphate dehydrogenase -2.39546
KCTD20 potassium channel tetramerization domain containing 20 -2.39236
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -2.36808
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 -2.36044
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -2.35862
CSF1R colony stimulating factor 1 receptor -2.35795
PTRF polymerase I and transcript release factor -2.35464
DERL1 derlin 1 -2.34323
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -2.32744
SUCLG1 succinate-CoA ligase, alpha subunit -2.32269
PROCR protein C receptor, endothelial -2.32141
ISCA2 iron-sulfur cluster assembly 2 -2.30008
NRP1 neuropilin 1 -2.29701
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -2.25646
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -2.24697
IVD isovaleryl-CoA dehydrogenase -2.23949
CS citrate synthase -2.23801
GIMAP4 GTPase, IMAP family member 4 -2.22329
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -2.17718
GYG1 glycogenin 1 -2.15766
DPP8 dipeptidyl-peptidase 8 -2.15003
GAS1 growth arrest-specific 1 -2.14512
ZNF467 zinc finger protein 467 -2.14317
TEK TEK tyrosine kinase, endothelial -2.13625
COMT catechol-O-methyltransferase -2.1332
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) -2.11778
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 -2.11519
LRRC58 leucine rich repeat containing 58 -2.11105
FLII flightless I homolog (Drosophila) -2.10865
EPHX2 epoxide hydrolase 2, cytoplasmic -2.10032
HADH hydroxyacyl-CoA dehydrogenase -2.09851
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.09821
PTPN9 protein tyrosine phosphatase, non-receptor type 9 -2.09752
ACO2 aconitase 2, mitochondrial -2.08358
ALAD aminolevulinate dehydratase -2.08184
PLIN4 perilipin 4 -2.06788
OSBPL11 oxysterol binding protein-like 11 -2.06352
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein -2.05683
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -2.04928
FBXO45 F-box protein 45 -2.04865
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -2.04684
NPC2 Niemann-Pick disease, type C2 -2.0462
DLD dihydrolipoamide dehydrogenase -2.04258
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -2.0391
TP63 tumor protein p63 -2.03713
KLF10 Kruppel-like factor 10 -2.03428
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -2.0337
TMEM43 transmembrane protein 43 -2.01946
FAP fibroblast activation protein, alpha -2.01236
TYSND1 trypsin domain containing 1 -2.01193
LMO2 LIM domain only 2 (rhombotin-like 1) -2.01159
LTBP4 latent transforming growth factor beta binding protein 4 -2.01152
C16ORF74 chromosome 16 open reading frame 74 -2.0046
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) -1.99757
C6ORF89 chromosome 6 open reading frame 89 -1.99662
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -1.99658
HSPA9 heat shock 70kDa protein 9 (mortalin) -1.99577
PTPRB protein tyrosine phosphatase, receptor type, B -1.9895
MCAM melanoma cell adhesion molecule -1.98882
PGAM2 phosphoglycerate mutase 2 (muscle) -1.98826
TCF4 transcription factor 4 -1.9844
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -1.97707
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -1.97681
PHKA2 phosphorylase kinase, alpha 2 (liver) -1.97468
PSME4 proteasome (prosome, macropain) activator subunit 4 -1.97448
TMEM245 transmembrane protein 245 -1.95343
EBF3 early B-cell factor 3 -1.93464
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) -1.93197
FMO1 flavin containing monooxygenase 1 -1.92935
QKI QKI, KH domain containing, RNA binding -1.92327
NNMT nicotinamide N-methyltransferase -1.92123
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 -1.91943
PRNP prion protein -1.91481
AK2 adenylate kinase 2 -1.91032
IL1R1 interleukin 1 receptor, type I -1.87753
RRAGC Ras-related GTP binding C -1.87183
ENG endoglin -1.87021
PXMP2 peroxisomal membrane protein 2, 22kDa -1.86132
PEX6 peroxisomal biogenesis factor 6 -1.85886
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -1.85538
LSM1 LSM1, U6 small nuclear RNA associated -1.85455
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 -1.84213
VAMP5 vesicle-associated membrane protein 5 -1.84178
ENPEP glutamyl aminopeptidase (aminopeptidase A) -1.83072
ENO3 enolase 3 (beta, muscle) -1.80281
SNCG synuclein, gamma (breast cancer-specific protein 1) -1.79809
TALDO1 transaldolase 1 -1.79741
CCDC101 coiled-coil domain containing 101 -1.79735
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -1.7952
LRP1 low density lipoprotein receptor-related protein 1 -1.79062
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -1.78997
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -1.78721
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -1.78543
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -1.77954
MRPL38 mitochondrial ribosomal protein L38 -1.77659
CHPT1 choline phosphotransferase 1 -1.77146
GPX3 glutathione peroxidase 3 -1.76674
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -1.76264
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase -1.75935
GPAM glycerol-3-phosphate acyltransferase, mitochondrial -1.75275
FABP4 fatty acid binding protein 4, adipocyte -1.74495
ACAA1 acetyl-CoA acyltransferase 1 -1.74262
EXTL3 exostosin-like glycosyltransferase 3 -1.74144
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -1.73936
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -1.73617
PNKP polynucleotide kinase 3'-phosphatase -1.73417
IGFBP6 insulin-like growth factor binding protein 6 -1.73196
HSPA14 heat shock 70kDa protein 14 -1.72473
RNASE4 ribonuclease, RNase A family, 4 -1.71949
TNIP1 TNFAIP3 interacting protein 1 -1.71563
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -1.71505
PDHB pyruvate dehydrogenase (lipoamide) beta -1.71434
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit -1.70242
STK10 serine/threonine kinase 10 -1.68493
ACLY ATP citrate lyase -1.67614
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -1.67069
ECE1 endothelin converting enzyme 1 -1.66291
UBAP1 ubiquitin associated protein 1 -1.66034
RXRG retinoid X receptor, gamma -1.6601
COX17 COX17 cytochrome c oxidase copper chaperone -1.65933
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -1.65529
MRPL16 mitochondrial ribosomal protein L16 -1.64714
BROX BRO1 domain and CAAX motif containing -1.64008
HTRA1 HtrA serine peptidase 1 -1.63499
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -1.63364
MRPL4 mitochondrial ribosomal protein L4 -1.63267
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -1.63253
RBP4 retinol binding protein 4, plasma -1.63241
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -1.62914
CEL carboxyl ester lipase -1.62847
TXNRD2 thioredoxin reductase 2 -1.60574
TMEM205 transmembrane protein 205 -1.60381
PNKD paroxysmal nonkinesigenic dyskinesia -1.59887
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -1.5988
KRT17 keratin 17, type I -1.59795
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -1.59793
C9ORF72 chromosome 9 open reading frame 72 -1.59009
CA3 carbonic anhydrase III -1.58852
GBE1 glucan (1,4-alpha-), branching enzyme 1 -1.56307
PID1 phosphotyrosine interaction domain containing 1 -1.55228
DGUOK deoxyguanosine kinase -1.55019
TNNI2 troponin I type 2 (skeletal, fast) -1.54841
ANXA5 annexin A5 -1.54586
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) -1.54064
FBXW4 F-box and WD repeat domain containing 4 -1.5367
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -1.52738
SHFM1 split hand/foot malformation (ectrodactyly) type 1 -1.52655
UBE2B ubiquitin-conjugating enzyme E2B -1.52429
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 -1.5239
TIMP3 TIMP metallopeptidase inhibitor 3 -1.52014
JCHAIN joining chain of multimeric IgA and IgM -1.51929
SVIL supervillin -1.51699
TPST1 tyrosylprotein sulfotransferase 1 -1.51525
MUT methylmalonyl CoA mutase -1.50194
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -1.49983
ECI1 enoyl-CoA delta isomerase 1 -1.49969
ACVR2A activin A receptor, type IIA -1.4996
GRK5 G protein-coupled receptor kinase 5 -1.49721
RAD23B RAD23 homolog B (S. cerevisiae) -1.49536
MAST3 microtubule associated serine/threonine kinase 3 -1.49519
NET1 neuroepithelial cell transforming 1 -1.48926
TWIST1 twist family bHLH transcription factor 1 -1.48859
MAT2A methionine adenosyltransferase II, alpha -1.48689
NCBP1 nuclear cap binding protein subunit 1, 80kDa -1.486
COL13A1 collagen, type XIII, alpha 1 -1.48556
ALAS1 5'-aminolevulinate synthase 1 -1.48346
KCTD17 potassium channel tetramerization domain containing 17 -1.48106
PMP22 peripheral myelin protein 22 -1.47337
VCAM1 vascular cell adhesion molecule 1 -1.4681
FAM107B family with sequence similarity 107, member B -1.46603
UNC119 unc-119 homolog (C. elegans) -1.4629
PCID2 PCI domain containing 2 -1.45999
DHRS7 dehydrogenase/reductase (SDR family) member 7 -1.45931
DYM dymeclin -1.45484
TKT transketolase -1.44999
BLCAP bladder cancer associated protein -1.44602
GHR growth hormone receptor -1.44503
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 -1.44498
COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae) -1.43847
PHYH phytanoyl-CoA 2-hydroxylase -1.43382
ANAPC5 anaphase promoting complex subunit 5 -1.43113
GTF2A1 general transcription factor IIA, 1, 19/37kDa -1.42008
COL6A1 collagen, type VI, alpha 1 -1.41337
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) -1.41233
INTS4 integrator complex subunit 4 -1.41119
KANK3 KN motif and ankyrin repeat domains 3 -1.40841
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -1.40476
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) -1.40413
DPYSL3 dihydropyrimidinase-like 3 -1.3957
ECH1 enoyl CoA hydratase 1, peroxisomal -1.39529
CDCA7 cell division cycle associated 7 -1.39319
ACAA2 acetyl-CoA acyltransferase 2 -1.39217
RSPO1 R-spondin 1 -1.3914
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -1.39025
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -1.38771
FSCN1 fascin actin-bundling protein 1 -1.38419
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa -1.38312
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -1.3829
PSEN2 presenilin 2 -1.38212
FST follistatin -1.37768
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -1.37767
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -1.37135
NPR3 natriuretic peptide receptor 3 -1.36438
NCKAP1 NCK-associated protein 1 -1.35895
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -1.35768
VWF von Willebrand factor -1.35544
NAV2 neuron navigator 2 -1.35208
POR P450 (cytochrome) oxidoreductase -1.34964
GJA3 gap junction protein, alpha 3, 46kDa -1.34459
MGLL monoglyceride lipase -1.34348
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -1.34307
RFX2 regulatory factor X, 2 (influences HLA class II expression) -1.34261
PTPRM protein tyrosine phosphatase, receptor type, M -1.33976
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -1.33573
COPS8 COP9 signalosome subunit 8 -1.3356
TRAK1 trafficking protein, kinesin binding 1 -1.33079
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -1.3288
PTOV1 prostate tumor overexpressed 1 -1.32877
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -1.3193
FASN fatty acid synthase -1.31123
NID1 nidogen 1 -1.31118
PRPS1 phosphoribosyl pyrophosphate synthetase 1 -1.3085
THRSP thyroid hormone responsive -1.30637
LAMA2 laminin, alpha 2 -1.30229
CDH5 cadherin 5, type 2 (vascular endothelium) -1.30063
NAP1L1 nucleosome assembly protein 1-like 1 -1.29978
TTC7B tetratricopeptide repeat domain 7B -1.29966
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -1.2994
C11ORF42 chromosome 11 open reading frame 42 -1.2979
CDAN1 codanin 1 -1.29578
STRN4 striatin, calmodulin binding protein 4 -1.29396
MYLK myosin light chain kinase -1.29193
ACSL1 acyl-CoA synthetase long-chain family member 1 -1.2904
CCDC12 coiled-coil domain containing 12 -1.28864
SOWAHC sosondowah ankyrin repeat domain family member C -1.28507
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) -1.28488
FZD4 frizzled class receptor 4 -1.28263
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -1.2825
STX4 syntaxin 4 -1.2781
CD34 CD34 molecule -1.27804
STAB1 stabilin 1 -1.27711
RNF19B ring finger protein 19B -1.27487
TMEM134 transmembrane protein 134 -1.2723
UQCRB ubiquinol-cytochrome c reductase binding protein -1.26911
PAK1IP1 PAK1 interacting protein 1 -1.26695
ELMOD3 ELMO/CED-12 domain containing 3 -1.2658
MAPK14 mitogen-activated protein kinase 14 -1.26253
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle -1.26054
FHL1 four and a half LIM domains 1 -1.26002
C8ORF33 chromosome 8 open reading frame 33 -1.25008
CFH complement factor H -1.24569
OGN osteoglycin -1.24479
APIP APAF1 interacting protein -1.24263
ANKFY1 ankyrin repeat and FYVE domain containing 1 -1.24255
CD47 CD47 molecule -1.24093
EIF3D eukaryotic translation initiation factor 3, subunit D -1.24066
COL18A1 collagen, type XVIII, alpha 1 -1.23904
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 -1.23879
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -1.2372
Funding