| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Brimonidine perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Brimonidine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.130361 |
| FOXO1 | forkhead box O1 | 0.110631 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.110073 |
| BCL2L1 | BCL2-like 1 | 0.0934299 |
| MSN | moesin | 0.0774847 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0656437 |
| NDRG1 | N-myc downstream regulated 1 | 0.0644569 |
| EZR | ezrin | 0.0638268 |
| POTEF | POTE ankyrin domain family, member F | 0.062233 |
| IGF2 | insulin-like growth factor 2 | 0.0594997 |
| NRG1 | neuregulin 1 | 0.0582713 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.054003 |
| EFHD2 | EF-hand domain family, member D2 | 0.0532443 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0518557 |
| RIN2 | Ras and Rab interactor 2 | 0.0470315 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0433717 |
| FOSL1 | FOS-like antigen 1 | 0.0407239 |
| CLU | clusterin | 0.0404015 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0399365 |
| TXNIP | thioredoxin interacting protein | 0.0394317 |
| CAPRIN2 | caprin family member 2 | 0.0390296 |
| TNS4 | tensin 4 | 0.0385932 |
| LUZP1 | leucine zipper protein 1 | 0.0379332 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0376083 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0370634 |
| OSMR | oncostatin M receptor | 0.0363111 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0362887 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0354648 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0353381 |
| NEK7 | NIMA-related kinase 7 | 0.0346407 |
| ITGA6 | integrin, alpha 6 | 0.0345056 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0333118 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0327482 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0321848 |
| MCL1 | myeloid cell leukemia 1 | 0.0321586 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0318402 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.031812 |
| B2M | beta-2-microglobulin | 0.0310602 |
| PLAT | plasminogen activator, tissue | 0.0310463 |
| TGM2 | transglutaminase 2 | 0.0309371 |
| FN1 | fibronectin 1 | 0.0304538 |
| CMIP | c-Maf inducing protein | 0.0303814 |
| EPHA2 | EPH receptor A2 | 0.0303648 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0298947 |
| METTL15 | methyltransferase like 15 | 0.0298725 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0295708 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0295463 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0295181 |
| PCDH1 | protocadherin 1 | 0.0293625 |
| MYOF | myoferlin | 0.0289663 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0288252 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.028818 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0287974 |
| LAMA5 | laminin, alpha 5 | 0.0287654 |
| IL6ST | interleukin 6 signal transducer | 0.02875 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.028202 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0281627 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.027626 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0266372 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0262812 |
| EHF | ets homologous factor | 0.0258199 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0258158 |
| PKM | pyruvate kinase, muscle | 0.0257385 |
| CUL4B | cullin 4B | 0.0257331 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0255418 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0253987 |
| YBX3 | Y box binding protein 3 | 0.025382 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0252478 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0251901 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.025035 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0239974 |
| LIMA1 | LIM domain and actin binding 1 | 0.0239148 |
| CD47 | CD47 molecule | 0.0238867 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0237102 |
| KIAA0040 | KIAA0040 | 0.0236604 |
| AXL | AXL receptor tyrosine kinase | 0.0235259 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0234991 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0234686 |
| MYADM | myeloid-associated differentiation marker | 0.0234421 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0234317 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0231459 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0229653 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0229252 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0228459 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0226787 |
| SERINC3 | serine incorporator 3 | 0.0224309 |
| ITGB4 | integrin, beta 4 | 0.0223919 |
| SEPTIN9 | septin 9 | 0.0222379 |
| CDK19 | cyclin-dependent kinase 19 | 0.0221558 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0221321 |
| WDR26 | WD repeat domain 26 | 0.021514 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0215052 |
| DIAPH3 | diaphanous-related formin 3 | 0.021123 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0210518 |
| NLRP1 | NLR family, pyrin domain containing 1 | 0.0208593 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0207145 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0206268 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0205269 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.020285 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0202536 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.147503 |
| MTSS1 | metastasis suppressor 1 | -0.139359 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.115077 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102719 |
| SLC35F3 | solute carrier family 35, member F3 | -0.101693 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0930045 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0918179 |
| INTS6 | integrator complex subunit 6 | -0.0904696 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0818049 |
| RPS8 | ribosomal protein S8 | -0.0811935 |
| PTMA | prothymosin, alpha | -0.0750659 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0662866 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0616648 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0605948 |
| RAI14 | retinoic acid induced 14 | -0.0595005 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0592856 |
| NAV2 | neuron navigator 2 | -0.0581609 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0551709 |
| RPS6 | ribosomal protein S6 | -0.0544466 |
| SULF2 | sulfatase 2 | -0.0543501 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0536429 |
| TMSB4X | thymosin beta 4, X-linked | -0.05291 |
| SQSTM1 | sequestosome 1 | -0.0522775 |
| LMO7 | LIM domain 7 | -0.0522016 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0514489 |
| S100A10 | S100 calcium binding protein A10 | -0.0506133 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0502494 |
| RPL34 | ribosomal protein L34 | -0.0497634 |
| STC1 | stanniocalcin 1 | -0.0490983 |
| ANXA1 | annexin A1 | -0.0490804 |
| AHNAK | AHNAK nucleoprotein | -0.0485236 |
| RPL35A | ribosomal protein L35a | -0.0482155 |
| TMSB10 | thymosin beta 10 | -0.0473359 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0472531 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0469349 |
| RPL12 | ribosomal protein L12 | -0.0468794 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0458334 |
| RPL23 | ribosomal protein L23 | -0.0455776 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0444256 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0443138 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0443019 |
| RPLP1 | ribosomal protein, large, P1 | -0.0436435 |
| RPS25 | ribosomal protein S25 | -0.0431008 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0414269 |
| RPS3 | ribosomal protein S3 | -0.0405298 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0401153 |
| RPL11 | ribosomal protein L11 | -0.0391471 |
| RPS24 | ribosomal protein S24 | -0.0390397 |
| RPL37 | ribosomal protein L37 | -0.0382201 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0379112 |
| RPS13 | ribosomal protein S13 | -0.0377606 |
| PTK2 | protein tyrosine kinase 2 | -0.0376331 |
| RPL19 | ribosomal protein L19 | -0.0371683 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0368135 |
| RPS19 | ribosomal protein S19 | -0.0361391 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0357161 |
| HMGA2 | high mobility group AT-hook 2 | -0.0347942 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.033969 |
| RPL26 | ribosomal protein L26 | -0.0334742 |
| RPS27A | ribosomal protein S27a | -0.0333667 |
| RPL37A | ribosomal protein L37a | -0.0333543 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0332831 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0332225 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0325583 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0324458 |
| RPS21 | ribosomal protein S21 | -0.032186 |
| LAMC2 | laminin, gamma 2 | -0.0321604 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0320575 |
| PRSS23 | protease, serine, 23 | -0.0319379 |
| RPL13A | ribosomal protein L13a | -0.0314705 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0312599 |
| PALLD | palladin, cytoskeletal associated protein | -0.0310899 |
| RPL31 | ribosomal protein L31 | -0.0310836 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.030786 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0306262 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0305096 |
| RPL8 | ribosomal protein L8 | -0.0300999 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0295919 |
| ASPH | aspartate beta-hydroxylase | -0.0295625 |
| RACK1 | receptor for activated C kinase 1 | -0.0293191 |
| RPS29 | ribosomal protein S29 | -0.0287838 |
| RPL5 | ribosomal protein L5 | -0.0286478 |
| RPL30 | ribosomal protein L30 | -0.0283277 |
| GNAS | GNAS complex locus | -0.0282403 |
| RPLP0 | ribosomal protein, large, P0 | -0.0282056 |
| ARF1 | ADP-ribosylation factor 1 | -0.0278756 |
| CSTB | cystatin B (stefin B) | -0.0271021 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0270198 |
| CANX | calnexin | -0.0265162 |
| RPS27 | ribosomal protein S27 | -0.0264695 |
| FTL | ferritin, light polypeptide | -0.0264485 |
| RPL7A | ribosomal protein L7a | -0.026253 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0258639 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0258278 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0255351 |
| RPL32 | ribosomal protein L32 | -0.0254452 |
| RPS16 | ribosomal protein S16 | -0.0249324 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0248876 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0247575 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0246277 |
