| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Brivudine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Brivudine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.180442 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.076602 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0673817 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0591881 |
| ANXA1 | annexin A1 | 0.0591732 |
| CALR | calreticulin | 0.0568145 |
| HSPA8 | heat shock 70kDa protein 8 | 0.04771 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.041243 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0405561 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.040029 |
| DST | dystonin | 0.0385275 |
| UBC | ubiquitin C | 0.0384519 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0370731 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0365293 |
| TPM3 | tropomyosin 3 | 0.0344298 |
| RRM2 | ribonucleotide reductase M2 | 0.033843 |
| CANX | calnexin | 0.0329385 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0320088 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0317272 |
| RPL3 | ribosomal protein L3 | 0.0316615 |
| ENO1 | enolase 1, (alpha) | 0.030179 |
| ASPH | aspartate beta-hydroxylase | 0.0294669 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.028989 |
| LDHA | lactate dehydrogenase A | 0.0289834 |
| PEG10 | paternally expressed 10 | 0.0287372 |
| AHNAK | AHNAK nucleoprotein | 0.0286632 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0282903 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.027963 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0264695 |
| INTS6 | integrator complex subunit 6 | 0.0263968 |
| HDAC9 | histone deacetylase 9 | 0.0258052 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0251898 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0242565 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0239284 |
| RPL4 | ribosomal protein L4 | 0.0238089 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0236001 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0233807 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0232901 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0228377 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.022185 |
| GOLGB1 | golgin B1 | 0.0221378 |
| DSPP | dentin sialophosphoprotein | 0.0216547 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.021651 |
| SET | SET nuclear proto-oncogene | 0.0212468 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0207056 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0205451 |
| BRD2 | bromodomain containing 2 | 0.0202842 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0201865 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0197786 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0196586 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0194842 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0191396 |
| WWOX | WW domain containing oxidoreductase | 0.0186483 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0185996 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.018457 |
| TPI1 | triosephosphate isomerase 1 | 0.018126 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0177656 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0176996 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0175974 |
| YAP1 | Yes-associated protein 1 | 0.0174845 |
| CTTN | cortactin | 0.0172558 |
| ADIPOR2 | adiponectin receptor 2 | 0.0172118 |
| H1-0 | H1.0 linker histone | 0.0171605 |
| FNIP1 | folliculin interacting protein 1 | 0.0168969 |
| TENM3 | teneurin transmembrane protein 3 | 0.0166392 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0165455 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0164789 |
| DENND5A | DENN/MADD domain containing 5A | 0.0164145 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0162423 |
| NRDC | nardilysin convertase | 0.0160846 |
| RPS3 | ribosomal protein S3 | 0.016011 |
| RPL14 | ribosomal protein L14 | 0.0159641 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0159242 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0158451 |
| NRXN3 | neurexin 3 | 0.0158045 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0157775 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.01565 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0155115 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0154721 |
| PCDH9 | protocadherin 9 | 0.0153531 |
| RTN3 | reticulon 3 | 0.0153321 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0153268 |
| USP53 | ubiquitin specific peptidase 53 | 0.01508 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0150446 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0149435 |
| AUTS2 | autism susceptibility candidate 2 | 0.0148452 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0147931 |
| RAB1A | RAB1A, member RAS oncogene family | 0.014674 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0145879 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0145719 |
| SPAG9 | sperm associated antigen 9 | 0.0143331 |
| OGA | O-GlcNAcase | 0.0140995 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0140605 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0139479 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0137552 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0137384 |
| AXIN2 | axin 2 | 0.0137172 |
| RPL37 | ribosomal protein L37 | 0.0135977 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.013517 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0134181 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.14396 |
| TMSB10 | thymosin beta 10 | -0.115091 |
| AREG | amphiregulin | -0.0627117 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0547039 |
| RPL35A | ribosomal protein L35a | -0.0531237 |
| NLGN1 | neuroligin 1 | -0.0498991 |
| PFN1 | profilin 1 | -0.0442186 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0378126 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0365808 |
| NHSL1 | NHS-like 1 | -0.0359939 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0348798 |
| KPNB1 | karyopherin (importin) beta 1 | -0.032944 |
| RPS21 | ribosomal protein S21 | -0.0325029 |
| HMGA1 | high mobility group AT-hook 1 | -0.0320319 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0307912 |
| RASAL2 | RAS protein activator like 2 | -0.0298705 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0285369 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0275933 |
| EGR1 | early growth response 1 | -0.0274121 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0270507 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0267403 |
| PCDH7 | protocadherin 7 | -0.0258124 |
| RPL11 | ribosomal protein L11 | -0.0247679 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0239017 |
| RPL36 | ribosomal protein L36 | -0.0234305 |
| FTL | ferritin, light polypeptide | -0.023236 |
| RPS6 | ribosomal protein S6 | -0.0230694 |
| RPS19 | ribosomal protein S19 | -0.0229172 |
| CCN2 | cellular communication network factor 2 | -0.022036 |
| RPLP1 | ribosomal protein, large, P1 | -0.0209723 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0207015 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0205493 |
| RPS16 | ribosomal protein S16 | -0.0205432 |
| EDN1 | endothelin 1 | -0.0205051 |
| PCBP2 | poly(rC) binding protein 2 | -0.0188431 |
| RPLP2 | ribosomal protein, large, P2 | -0.0183807 |
| YBX3 | Y box binding protein 3 | -0.0181787 |
| WDR43 | WD repeat domain 43 | -0.0181209 |
| KIF18B | kinesin family member 18B | -0.0180195 |
| RPS23 | ribosomal protein S23 | -0.0167225 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0165777 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0165689 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0165258 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0163683 |
| CBX3 | chromobox homolog 3 | -0.0159187 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0158342 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.015792 |
| EDARADD | EDAR-associated death domain | -0.0154156 |
| RPL28 | ribosomal protein L28 | -0.015286 |
| TMEM123 | transmembrane protein 123 | -0.0150041 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0146331 |
| GCG | glucagon | -0.0145732 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0140177 |
| PRR11 | proline rich 11 | -0.0140109 |
| RBM25 | RNA binding motif protein 25 | -0.0138802 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0138171 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0137465 |
| RPS26 | ribosomal protein S26 | -0.0136653 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0133752 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.013073 |
| ZNF804A | zinc finger protein 804A | -0.013047 |
| RPS14 | ribosomal protein S14 | -0.0128437 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0127183 |
| RPL23 | ribosomal protein L23 | -0.0126667 |
| RPL34 | ribosomal protein L34 | -0.0126278 |
| RPL8 | ribosomal protein L8 | -0.0126128 |
| RPL32 | ribosomal protein L32 | -0.0125341 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0125018 |
| RPL9 | ribosomal protein L9 | -0.0124997 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0123934 |
| S100A9 | S100 calcium binding protein A9 | -0.0123508 |
| RPL38 | ribosomal protein L38 | -0.0122513 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0120878 |
| CENPF | centromere protein F, 350/400kDa | -0.0120805 |
| RPL37A | ribosomal protein L37a | -0.0120805 |
| FAM3C | family with sequence similarity 3, member C | -0.0119188 |
| NAV3 | neuron navigator 3 | -0.0118754 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.011698 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0114659 |
| RPL36A | ribosomal protein L36a | -0.01134 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0113363 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.011234 |
| RPLP0 | ribosomal protein, large, P0 | -0.0112326 |
| RPL19 | ribosomal protein L19 | -0.0112267 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0112136 |
| HMGB1 | high mobility group box 1 | -0.0111025 |
| RPS15 | ribosomal protein S15 | -0.011083 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0109588 |
| JMJD1C | jumonji domain containing 1C | -0.0109112 |
| BTG3 | BTG family, member 3 | -0.0108977 |
| S100A6 | S100 calcium binding protein A6 | -0.0108481 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0108479 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0108404 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0107443 |
| TMEM41B | transmembrane protein 41B | -0.0106983 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0106364 |
| CDK17 | cyclin-dependent kinase 17 | -0.010591 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0104399 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0103982 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0102726 |
