| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Brivudine perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Brivudine_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.176983 |
| EGFR | epidermal growth factor receptor | 0.17491 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0909277 |
| CANX | calnexin | 0.05242 |
| PTMA | prothymosin, alpha | 0.0503162 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0492667 |
| INTS6 | integrator complex subunit 6 | 0.0463846 |
| LMO7 | LIM domain 7 | 0.0459794 |
| ASPH | aspartate beta-hydroxylase | 0.0450565 |
| ENO1 | enolase 1, (alpha) | 0.0441863 |
| FAM13A | family with sequence similarity 13, member A | 0.04137 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0397774 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0396705 |
| DSCAM | Down syndrome cell adhesion molecule | 0.037637 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0370415 |
| UBC | ubiquitin C | 0.0369619 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0345584 |
| HDLBP | high density lipoprotein binding protein | 0.0330531 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0321345 |
| TOP1 | topoisomerase (DNA) I | 0.031854 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0316017 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0312089 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0309232 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0306826 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0306288 |
| AHNAK | AHNAK nucleoprotein | 0.0303979 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0302598 |
| OGA | O-GlcNAcase | 0.030149 |
| H1-0 | H1.0 linker histone | 0.029956 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0299504 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0295377 |
| HYOU1 | hypoxia up-regulated 1 | 0.0293429 |
| RPS3 | ribosomal protein S3 | 0.029065 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0285553 |
| SPAG9 | sperm associated antigen 9 | 0.0279741 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0276692 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0271782 |
| HOMER1 | homer scaffolding protein 1 | 0.0270587 |
| ARRDC3 | arrestin domain containing 3 | 0.0265191 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0265098 |
| PAPOLA | poly(A) polymerase alpha | 0.0264666 |
| GOLGB1 | golgin B1 | 0.026454 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0263902 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0263817 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0263431 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0261226 |
| MYOF | myoferlin | 0.0256926 |
| ENSA | endosulfine alpha | 0.0254183 |
| SMAD3 | SMAD family member 3 | 0.0254048 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0253437 |
| CALR | calreticulin | 0.0252007 |
| PYGL | phosphorylase, glycogen, liver | 0.0250942 |
| SLTM | SAFB-like, transcription modulator | 0.0250221 |
| ANO6 | anoctamin 6 | 0.0247219 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0246005 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0242104 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0235023 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0233505 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0230368 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0228548 |
| HELZ | helicase with zinc finger | 0.0227935 |
| DSPP | dentin sialophosphoprotein | 0.0224008 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0223614 |
| UVRAG | UV radiation resistance associated | 0.0221636 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0221606 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0220954 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0217225 |
| HBP1 | HMG-box transcription factor 1 | 0.0216033 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0213855 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0213792 |
| MORF4L2 | mortality factor 4 like 2 | 0.0209944 |
| RPL4 | ribosomal protein L4 | 0.020465 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0204649 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0204022 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0202854 |
| DTNA | dystrobrevin, alpha | 0.0202512 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0199836 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0198815 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0198244 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0197678 |
| RBM39 | RNA binding motif protein 39 | 0.0197354 |
| SP100 | SP100 nuclear antigen | 0.0195174 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0194628 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0193496 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0191832 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0190854 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0190318 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0189656 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0189566 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0187755 |
| NPTN | neuroplastin | 0.0186013 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0182238 |
| SEC24A | SEC24 family member A | 0.0181236 |
| ABLIM1 | actin binding LIM protein 1 | 0.017795 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0177913 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0177243 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0176488 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0175614 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0172475 |
| ATXN1 | ataxin 1 | 0.0171711 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.159123 |
| TXNRD1 | thioredoxin reductase 1 | -0.131317 |
| TMSB10 | thymosin beta 10 | -0.100573 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0945601 |
| MT2A | metallothionein 2A | -0.0906537 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.088045 |
| OSMR | oncostatin M receptor | -0.0688988 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0605765 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0581395 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0576539 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0562062 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0497577 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.048644 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0474678 |
| CST3 | cystatin C | -0.046031 |
| LAMA4 | laminin, alpha 4 | -0.0447395 |
| FTL | ferritin, light polypeptide | -0.0399274 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0357867 |
| EGR1 | early growth response 1 | -0.0357496 |
| NDRG1 | N-myc downstream regulated 1 | -0.0317615 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.031274 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0312167 |
| AREG | amphiregulin | -0.0304033 |
| LAMC2 | laminin, gamma 2 | -0.0280782 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0273064 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0257298 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0253003 |
| ACTG1 | actin gamma 1 | -0.0251193 |
| CAV2 | caveolin 2 | -0.0250315 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0248305 |
| SCEL | sciellin | -0.0248191 |
| CCNL1 | cyclin L1 | -0.0245481 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.024324 |
| RPL35A | ribosomal protein L35a | -0.0238096 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0237045 |
| S100A11 | S100 calcium binding protein A11 | -0.0229554 |
| KRT7 | keratin 7, type II | -0.0220969 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0207474 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0207404 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0204834 |
| RTN4 | reticulon 4 | -0.0201782 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0199383 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0194445 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0193551 |
| TJP1 | tight junction protein 1 | -0.0192882 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0192643 |
| S100A9 | S100 calcium binding protein A9 | -0.0188264 |
| EFNA5 | ephrin-A5 | -0.0187945 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0186177 |
| PRDX1 | peroxiredoxin 1 | -0.0181155 |
| POTEF | POTE ankyrin domain family, member F | -0.0177572 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0169161 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0169043 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0166429 |
| SYAP1 | synapse associated protein 1 | -0.0164552 |
| VCL | vinculin | -0.0157532 |
| NPC1 | Niemann-Pick disease, type C1 | -0.015643 |
| MT1X | metallothionein 1X | -0.0155901 |
| CCND1 | cyclin D1 | -0.0154371 |
| PFN1 | profilin 1 | -0.0152316 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0149645 |
| HMGA1 | high mobility group AT-hook 1 | -0.0146073 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0145852 |
| KRT18 | keratin 18, type I | -0.0144564 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0144225 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0144191 |
| MYO1D | myosin ID | -0.0143963 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0143947 |
| RNF149 | ring finger protein 149 | -0.0143231 |
| B2M | beta-2-microglobulin | -0.0142832 |
| RPL11 | ribosomal protein L11 | -0.014249 |
| RPS21 | ribosomal protein S21 | -0.0136975 |
| KRT19 | keratin 19, type I | -0.0135465 |
| CHML | choroideremia-like (Rab escort protein 2) | -0.0132997 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0129875 |
| NABP1 | nucleic acid binding protein 1 | -0.012964 |
| MKI67 | marker of proliferation Ki-67 | -0.0128858 |
| TPM4 | tropomyosin 4 | -0.0127715 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.01274 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0127273 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0124806 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0123499 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0122911 |
| XDH | xanthine dehydrogenase | -0.0122909 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0122256 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0121952 |
| MAGEA4 | melanoma antigen family A4 | -0.0121838 |
| STC1 | stanniocalcin 1 | -0.0120479 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0119803 |
| KIFC3 | kinesin family member C3 | -0.0119735 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0119492 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0118962 |
| PKM | pyruvate kinase, muscle | -0.0118822 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0117459 |
| FOSL1 | FOS-like antigen 1 | -0.0115429 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0115297 |
| NTN4 | netrin 4 | -0.0113972 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0113725 |
| RPS19 | ribosomal protein S19 | -0.0112173 |
| KRT8 | keratin 8, type II | -0.0111692 |
