| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Brivudine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Brivudine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.11184 |
| NAV2 | neuron navigator 2 | 0.108052 |
| EFNA5 | ephrin-A5 | 0.0911371 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0718924 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0703076 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0665781 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0652498 |
| VEGFA | vascular endothelial growth factor A | 0.0629192 |
| PRELID2 | PRELI domain containing 2 | 0.0627068 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0604443 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.059633 |
| ANGPTL4 | angiopoietin-like 4 | 0.0512007 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0471283 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0464279 |
| FAM20C | family with sequence similarity 20, member C | 0.0452033 |
| ENO1 | enolase 1, (alpha) | 0.045172 |
| ASPH | aspartate beta-hydroxylase | 0.0430931 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0427826 |
| RAD51B | RAD51 paralog B | 0.0424919 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0388111 |
| EGFR | epidermal growth factor receptor | 0.0375714 |
| LRRC49 | leucine rich repeat containing 49 | 0.036777 |
| INTS6 | integrator complex subunit 6 | 0.0367438 |
| SMAD3 | SMAD family member 3 | 0.034917 |
| RPL4 | ribosomal protein L4 | 0.0342852 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0342783 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0339134 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.033497 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0333918 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0330966 |
| GPC6 | glypican 6 | 0.0328963 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0328916 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0325764 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0320771 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0314202 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0305319 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0304269 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0303547 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0302803 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0301699 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0297552 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0288555 |
| RPL3 | ribosomal protein L3 | 0.0287307 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0282714 |
| LDHA | lactate dehydrogenase A | 0.0281819 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0278475 |
| MCL1 | myeloid cell leukemia 1 | 0.0276308 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0273087 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0269978 |
| HDAC9 | histone deacetylase 9 | 0.0268366 |
| ZNF638 | zinc finger protein 638 | 0.0265798 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0265243 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.026498 |
| RARB | retinoic acid receptor, beta | 0.02647 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0263893 |
| RUNX1 | runt-related transcription factor 1 | 0.0257093 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0256599 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0253138 |
| MYOF | myoferlin | 0.0247645 |
| KIAA1217 | KIAA1217 | 0.0247523 |
| RPL37 | ribosomal protein L37 | 0.0244967 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0244392 |
| RPS12 | ribosomal protein S12 | 0.0244131 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0243893 |
| ECE1 | endothelin converting enzyme 1 | 0.0242817 |
| RPS3 | ribosomal protein S3 | 0.0240659 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0240634 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0240408 |
| CANX | calnexin | 0.0239838 |
| ATXN1 | ataxin 1 | 0.0239331 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0239137 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0238396 |
| CDCP1 | CUB domain containing protein 1 | 0.0235014 |
| RPS17 | ribosomal protein S17 | 0.0234426 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0233988 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0232688 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0232494 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0231501 |
| LOXL2 | lysyl oxidase-like 2 | 0.0230967 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0230475 |
| CEP250 | centrosomal protein 250kDa | 0.022928 |
| SEPTIN9 | septin 9 | 0.0228319 |
| UBC | ubiquitin C | 0.0226853 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.022368 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0218438 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0215878 |
| FRMD4A | FERM domain containing 4A | 0.0206309 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0204142 |
| SQSTM1 | sequestosome 1 | 0.0202125 |
| BPTF | bromodomain PHD finger transcription factor | 0.0201767 |
| NBAS | neuroblastoma amplified sequence | 0.019714 |
| RPS8 | ribosomal protein S8 | 0.0194291 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0193615 |
| GOLGB1 | golgin B1 | 0.0191421 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0189404 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0189248 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0187372 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0186595 |
| RPL23 | ribosomal protein L23 | 0.0185701 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0183347 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.210294 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.127952 |
| GLCCI1 | glucocorticoid induced 1 | -0.119277 |
| TMSB10 | thymosin beta 10 | -0.102723 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0911865 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0776619 |
| FTL | ferritin, light polypeptide | -0.0762653 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0728869 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0693539 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0666159 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0633758 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0631182 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.062051 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0599337 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0586553 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0570623 |
| HMGA2 | high mobility group AT-hook 2 | -0.0565334 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0548208 |
| OXSR1 | oxidative stress responsive 1 | -0.0539776 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0521516 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0512544 |
| NRG1 | neuregulin 1 | -0.0510666 |
| SYT1 | synaptotagmin I | -0.0507686 |
| MEF2A | myocyte enhancer factor 2A | -0.0487817 |
| PRR16 | proline rich 16 | -0.0486911 |
| PTMA | prothymosin, alpha | -0.0474639 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0462224 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0451742 |
| STC1 | stanniocalcin 1 | -0.0435346 |
| MAP1B | microtubule-associated protein 1B | -0.0434433 |
| RAI14 | retinoic acid induced 14 | -0.0424026 |
| VRK2 | vaccinia related kinase 2 | -0.0419641 |
| PARD3 | par-3 family cell polarity regulator | -0.0419479 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0417227 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0415704 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0412378 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0396443 |
| LOX | lysyl oxidase | -0.039572 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0389426 |
| S100A6 | S100 calcium binding protein A6 | -0.0387859 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0387337 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0379764 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0366941 |
| NTN4 | netrin 4 | -0.0366726 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0364787 |
| RNF24 | ring finger protein 24 | -0.0363548 |
| JMJD1C | jumonji domain containing 1C | -0.0362419 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0359628 |
| SYAP1 | synapse associated protein 1 | -0.0359368 |
| NRP1 | neuropilin 1 | -0.0357345 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0353819 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.034984 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0347304 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0344155 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0344097 |
| SETD5 | SET domain containing 5 | -0.0341037 |
| RBM39 | RNA binding motif protein 39 | -0.0340137 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0337229 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0334001 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0332989 |
| USP3 | ubiquitin specific peptidase 3 | -0.0329685 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0328843 |
| VIM | vimentin | -0.0328402 |
| OSMR | oncostatin M receptor | -0.0327231 |
| RIOK3 | RIO kinase 3 | -0.0325542 |
| CCDC88A | coiled-coil domain containing 88A | -0.0324404 |
| SPAG9 | sperm associated antigen 9 | -0.0321183 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0320108 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0318956 |
| CLMP | CXADR-like membrane protein | -0.0318429 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0314127 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0312011 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0308178 |
| FBN1 | fibrillin 1 | -0.0306148 |
| PRRX1 | paired related homeobox 1 | -0.0300412 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0296414 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0295903 |
| TMEM131 | transmembrane protein 131 | -0.0295256 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0294659 |
| CDK14 | cyclin-dependent kinase 14 | -0.0293273 |
| MECOM | MDS1 and EVI1 complex locus | -0.0291866 |
| SNX9 | sorting nexin 9 | -0.0288305 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0283789 |
| MTSS1 | metastasis suppressor 1 | -0.0278836 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0275852 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0274905 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0272804 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0268775 |
| NAV3 | neuron navigator 3 | -0.0268024 |
| RASAL2 | RAS protein activator like 2 | -0.0266864 |
| FBXO11 | F-box protein 11 | -0.0265843 |
| BMERB1 | bMERB domain containing 1 | -0.0264105 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.026402 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0263743 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0263183 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0262124 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0261871 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0259233 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0258463 |
| PFN1 | profilin 1 | -0.0257711 |
