| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Brivudine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Brivudine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.286745 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.18844 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.155835 |
| MCL1 | myeloid cell leukemia 1 | 0.144356 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.12016 |
| PM20D1 | peptidase M20 domain containing 1 | 0.10042 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0996863 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0830012 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0767672 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0741842 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0727638 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0718544 |
| EGR1 | early growth response 1 | 0.0670862 |
| CALR | calreticulin | 0.0663261 |
| RPL4 | ribosomal protein L4 | 0.0662867 |
| RPL3 | ribosomal protein L3 | 0.0639493 |
| UBC | ubiquitin C | 0.0608546 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0594746 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0594744 |
| APP | amyloid beta (A4) precursor protein | 0.0577431 |
| BRD2 | bromodomain containing 2 | 0.0572694 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0549872 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0518198 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0485031 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0481229 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0471923 |
| ASPH | aspartate beta-hydroxylase | 0.0469019 |
| IER3 | immediate early response 3 | 0.0460214 |
| RRM2 | ribonucleotide reductase M2 | 0.0445566 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0442394 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0434691 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0425965 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.042014 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0417806 |
| TPM3 | tropomyosin 3 | 0.041021 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0409421 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0408652 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0405764 |
| SPAG9 | sperm associated antigen 9 | 0.0374157 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0373936 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0371222 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0365754 |
| SFTPA2 | surfactant protein A2 | 0.036249 |
| RBM39 | RNA binding motif protein 39 | 0.0362041 |
| VMP1 | vacuole membrane protein 1 | 0.0351297 |
| RPL23 | ribosomal protein L23 | 0.0350387 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0346798 |
| FUS | FUS RNA binding protein | 0.0342237 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.03415 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0326027 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0324651 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0310326 |
| YBX1 | Y box binding protein 1 | 0.0307885 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0305518 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0305036 |
| SDC4 | syndecan 4 | 0.0301344 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0300114 |
| RPN2 | ribophorin II | 0.0294396 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0293562 |
| ENO1 | enolase 1, (alpha) | 0.0286997 |
| EZR | ezrin | 0.0285328 |
| FAM107B | family with sequence similarity 107, member B | 0.0279969 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0278523 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0274437 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0270639 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0267254 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0266459 |
| COPA | coatomer protein complex, subunit alpha | 0.0266003 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0265416 |
| GOLGB1 | golgin B1 | 0.0264499 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0264074 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0263563 |
| PDE10A | phosphodiesterase 10A | 0.0263008 |
| BMP6 | bone morphogenetic protein 6 | 0.0261718 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0261292 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0261051 |
| CCNL1 | cyclin L1 | 0.0261002 |
| MORF4L2 | mortality factor 4 like 2 | 0.0258955 |
| RPS18 | ribosomal protein S18 | 0.0257895 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0252691 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0250383 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0249434 |
| B2M | beta-2-microglobulin | 0.0248017 |
| WWOX | WW domain containing oxidoreductase | 0.0247808 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0246787 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0245371 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0243725 |
| CANX | calnexin | 0.0242725 |
| TPI1 | triosephosphate isomerase 1 | 0.024252 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0241494 |
| RPL13A | ribosomal protein L13a | 0.0241149 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0240541 |
| RPS3 | ribosomal protein S3 | 0.0240414 |
| CALU | calumenin | 0.0239862 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0238272 |
| RPL37 | ribosomal protein L37 | 0.0234128 |
| HBP1 | HMG-box transcription factor 1 | 0.0231542 |
| DENND4A | DENN/MADD domain containing 4A | 0.0231437 |
| NABP1 | nucleic acid binding protein 1 | 0.0231154 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0229987 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.216818 |
| VIM | vimentin | -0.21238 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.201518 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.160398 |
| CMIP | c-Maf inducing protein | -0.124482 |
| IGF2 | insulin-like growth factor 2 | -0.0882297 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.082914 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0630079 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0629744 |
| TMSB10 | thymosin beta 10 | -0.0628188 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0599924 |
| ACTG1 | actin gamma 1 | -0.0571669 |
| PFN1 | profilin 1 | -0.0560934 |
| TPM4 | tropomyosin 4 | -0.053881 |
| BICC1 | BicC family RNA binding protein 1 | -0.0508034 |
| PYGL | phosphorylase, glycogen, liver | -0.0503958 |
| FLNB | filamin B, beta | -0.0491366 |
| ERBIN | erbb2 interacting protein | -0.0484055 |
| HMGA1 | high mobility group AT-hook 1 | -0.0442221 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0437401 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.042312 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0419578 |
| FMNL2 | formin-like 2 | -0.0401884 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0399291 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0392609 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0388798 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0387939 |
| CFDP1 | craniofacial development protein 1 | -0.0387931 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0386818 |
| AK1 | adenylate kinase 1 | -0.0382096 |
| EGFR | epidermal growth factor receptor | -0.0380301 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0379174 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0375628 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0369648 |
| RPL35A | ribosomal protein L35a | -0.0369014 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0367223 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0363967 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0359892 |
| PRR16 | proline rich 16 | -0.0354332 |
| DENND5B | DENN/MADD domain containing 5B | -0.0348565 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0343456 |
| PTMA | prothymosin, alpha | -0.0328927 |
| UTRN | utrophin | -0.0328869 |
| S100A6 | S100 calcium binding protein A6 | -0.0328215 |
| PDE8A | phosphodiesterase 8A | -0.0327209 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0323559 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0320987 |
| ZFHX3 | zinc finger homeobox 3 | -0.0319543 |
| LMNA | lamin A/C | -0.031796 |
| FOXP1 | forkhead box P1 | -0.0317903 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0317775 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0304873 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0303381 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0302908 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0297585 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0297322 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0293362 |
| EHBP1 | EH domain binding protein 1 | -0.0291541 |
| EFNA5 | ephrin-A5 | -0.0290575 |
| NDRG1 | N-myc downstream regulated 1 | -0.0288267 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0287944 |
| RASAL2 | RAS protein activator like 2 | -0.0285611 |
| NEGR1 | neuronal growth regulator 1 | -0.028505 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0284788 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0284695 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0282141 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0277478 |
| HMGA2 | high mobility group AT-hook 2 | -0.0274852 |
| PHF20 | PHD finger protein 20 | -0.0267716 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0267323 |
| CUX1 | cut-like homeobox 1 | -0.0265606 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0265318 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0261878 |
| NEBL | nebulette | -0.0261809 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.025679 |
| TPD52 | tumor protein D52 | -0.0253017 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0250768 |
| PKM | pyruvate kinase, muscle | -0.0247075 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0246881 |
| YY1 | YY1 transcription factor | -0.0244467 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0242834 |
| SNX6 | sorting nexin 6 | -0.0241074 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0239797 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.02356 |
| PRKCE | protein kinase C, epsilon | -0.0235574 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0231712 |
| RNF217 | ring finger protein 217 | -0.0231408 |
| NHSL1 | NHS-like 1 | -0.0230173 |
| NAV3 | neuron navigator 3 | -0.0228888 |
| TMEM131 | transmembrane protein 131 | -0.0227056 |
| PCNX4 | pecanex 4 | -0.02268 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0225798 |
| ASTN2 | astrotactin 2 | -0.0225403 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0224475 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0224444 |
| FRMD6 | FERM domain containing 6 | -0.0223126 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.022121 |
| USP34 | ubiquitin specific peptidase 34 | -0.0221116 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0221107 |
| NRG1 | neuregulin 1 | -0.0220095 |
