| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Brivudine perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Brivudine_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.210862 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.174305 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.124599 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.101471 |
| TPM3 | tropomyosin 3 | 0.0778936 |
| ENO1 | enolase 1, (alpha) | 0.0745299 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0713663 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0712179 |
| RPS3 | ribosomal protein S3 | 0.0706842 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.068569 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0624339 |
| DST | dystonin | 0.0615396 |
| ACTG1 | actin gamma 1 | 0.0614951 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0614714 |
| UBC | ubiquitin C | 0.0608699 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0576133 |
| RPL3 | ribosomal protein L3 | 0.0562994 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0557955 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0551305 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0549919 |
| GOLGB1 | golgin B1 | 0.0545717 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0509767 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0504854 |
| RPL4 | ribosomal protein L4 | 0.0496419 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0493017 |
| VCL | vinculin | 0.0490075 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0472163 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0470961 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0457946 |
| CALR | calreticulin | 0.04564 |
| INTS6 | integrator complex subunit 6 | 0.0456295 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0420003 |
| BRD2 | bromodomain containing 2 | 0.0418391 |
| CTTN | cortactin | 0.0411746 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0408037 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0407735 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.040633 |
| RPS4X | ribosomal protein S4, X-linked | 0.0401169 |
| SFTPA2 | surfactant protein A2 | 0.0395196 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0393168 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0390941 |
| DSPP | dentin sialophosphoprotein | 0.0386706 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0379932 |
| LDHA | lactate dehydrogenase A | 0.0375344 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0372179 |
| AHNAK | AHNAK nucleoprotein | 0.0362427 |
| RPL37 | ribosomal protein L37 | 0.0361323 |
| RPS8 | ribosomal protein S8 | 0.0349277 |
| SYT1 | synaptotagmin I | 0.0346774 |
| ATF6 | activating transcription factor 6 | 0.0346148 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0343941 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0343212 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0339577 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0337719 |
| CANX | calnexin | 0.0337453 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0334385 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0329066 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0324245 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0320385 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0318307 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0317538 |
| RPS12 | ribosomal protein S12 | 0.0312984 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0310915 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0309151 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0296393 |
| AEBP2 | AE binding protein 2 | 0.0295222 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0293822 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0290346 |
| SET | SET nuclear proto-oncogene | 0.0290023 |
| CALD1 | caldesmon 1 | 0.0289874 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.02893 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0289187 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0288981 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0286623 |
| RPS27A | ribosomal protein S27a | 0.0281357 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0280995 |
| POTEF | POTE ankyrin domain family, member F | 0.0280597 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.027986 |
| H1-0 | H1.0 linker histone | 0.0278498 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0276758 |
| SPAG9 | sperm associated antigen 9 | 0.0275385 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0274137 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.027142 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.027125 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0269871 |
| TPI1 | triosephosphate isomerase 1 | 0.0265974 |
| MCL1 | myeloid cell leukemia 1 | 0.0263474 |
| WWOX | WW domain containing oxidoreductase | 0.0263159 |
| B2M | beta-2-microglobulin | 0.0262063 |
| RPS18 | ribosomal protein S18 | 0.0261359 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | 0.0260889 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0260876 |
| CALU | calumenin | 0.0260499 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0258036 |
| VCP | valosin containing protein | 0.0254717 |
| RRM2 | ribonucleotide reductase M2 | 0.0253755 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0252089 |
| RPS17 | ribosomal protein S17 | 0.0249433 |
| CLTC | clathrin, heavy chain (Hc) | 0.0246817 |
| RPL23 | ribosomal protein L23 | 0.0244968 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0665094 |
| BBX | bobby sox homolog (Drosophila) | -0.0649238 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0593823 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0583639 |
| PFN1 | profilin 1 | -0.057883 |
| PHIP | pleckstrin homology domain interacting protein | -0.0575512 |
| RSF1 | remodeling and spacing factor 1 | -0.0562378 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0538984 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0530981 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0507051 |
| CCNL1 | cyclin L1 | -0.0485915 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0476525 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0464522 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0442641 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0438605 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0414858 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0409442 |
| PHF21A | PHD finger protein 21A | -0.0406249 |
| TMEM165 | transmembrane protein 165 | -0.0395806 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0395732 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0385859 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0385009 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0374813 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0369524 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0367259 |
| RTN4 | reticulon 4 | -0.0358979 |
| KMT5B | lysine methyltransferase 5B | -0.0342642 |
| RPL35A | ribosomal protein L35a | -0.0339497 |
| XPO1 | exportin 1 | -0.0338418 |
| IGF2 | insulin-like growth factor 2 | -0.0337918 |
| ZNF292 | zinc finger protein 292 | -0.033544 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0330598 |
| PCBP2 | poly(rC) binding protein 2 | -0.0326398 |
| RBM25 | RNA binding motif protein 25 | -0.0318275 |
| PHF20 | PHD finger protein 20 | -0.0313142 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0310987 |
| FMNL2 | formin-like 2 | -0.0306437 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0304841 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0301956 |
| USP34 | ubiquitin specific peptidase 34 | -0.0299979 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0298384 |
| RAD51B | RAD51 paralog B | -0.0294349 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0292577 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0289438 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0285896 |
| HMGA1 | high mobility group AT-hook 1 | -0.0285355 |
| ZNF148 | zinc finger protein 148 | -0.0284504 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0281943 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0278338 |
| PTK2 | protein tyrosine kinase 2 | -0.0275899 |
| SETD5 | SET domain containing 5 | -0.0274624 |
| ZNF207 | zinc finger protein 207 | -0.0273856 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0270144 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.026981 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.0268798 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.026855 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0267145 |
| TFG | TRK-fused gene | -0.0267062 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0266804 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0265633 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0263811 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0263064 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0260999 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0260109 |
| PCNX1 | pecanex 1 | -0.0255376 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0255133 |
| TXNRD1 | thioredoxin reductase 1 | -0.0253903 |
| ATXN2 | ataxin 2 | -0.0251876 |
| TNPO3 | transportin 3 | -0.025173 |
| FBXO11 | F-box protein 11 | -0.0251684 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.025077 |
| RBM39 | RNA binding motif protein 39 | -0.0248305 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.024829 |
| GNAS | GNAS complex locus | -0.0246669 |
| TMSB10 | thymosin beta 10 | -0.0246299 |
| OGA | O-GlcNAcase | -0.0244882 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0241566 |
| SBF2 | SET binding factor 2 | -0.0235507 |
| IKBIP | IKBKB interacting protein | -0.0235228 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0232724 |
| TBK1 | TANK-binding kinase 1 | -0.023162 |
| OSMR | oncostatin M receptor | -0.0230647 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0230447 |
| NF1 | neurofibromin 1 | -0.0228937 |
| NEMF | nuclear export mediator factor | -0.0227816 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.022682 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0225151 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0224228 |
| NKTR | natural killer cell triggering receptor | -0.0223923 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0218855 |
| CDK19 | cyclin-dependent kinase 19 | -0.0218598 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0217411 |
| SNX9 | sorting nexin 9 | -0.0216716 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0216591 |
| TLK1 | tousled-like kinase 1 | -0.0214261 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0213548 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0212737 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0212366 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0212027 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0210024 |
