| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Brivudine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Brivudine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.237729 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.212807 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.203951 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.179003 |
| PTMA | prothymosin, alpha | 0.140666 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.126494 |
| FTL | ferritin, light polypeptide | 0.105784 |
| CALR | calreticulin | 0.101102 |
| UBC | ubiquitin C | 0.100875 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0963953 |
| ACTG1 | actin gamma 1 | 0.0810279 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0785202 |
| ASPH | aspartate beta-hydroxylase | 0.0733276 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0720081 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0703895 |
| LDHA | lactate dehydrogenase A | 0.0676374 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0663513 |
| ENO1 | enolase 1, (alpha) | 0.0614921 |
| RPS3 | ribosomal protein S3 | 0.059739 |
| POTEF | POTE ankyrin domain family, member F | 0.0582105 |
| GOLGA4 | golgin A4 | 0.0569753 |
| CANX | calnexin | 0.0552414 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0536115 |
| SPAG9 | sperm associated antigen 9 | 0.0529595 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0516348 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.051634 |
| SDC4 | syndecan 4 | 0.0514201 |
| TPM3 | tropomyosin 3 | 0.0513289 |
| FN1 | fibronectin 1 | 0.0497357 |
| MYO6 | myosin VI | 0.0484453 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0478145 |
| CCNL1 | cyclin L1 | 0.0476835 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0462469 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0452279 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0449831 |
| COPA | coatomer protein complex, subunit alpha | 0.0443324 |
| CALU | calumenin | 0.0440225 |
| RBM25 | RNA binding motif protein 25 | 0.0436188 |
| PKM | pyruvate kinase, muscle | 0.0435434 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0434558 |
| YTHDC1 | YTH domain containing 1 | 0.0432343 |
| SMYD3 | SET and MYND domain containing 3 | 0.0431203 |
| TPR | translocated promoter region, nuclear basket protein | 0.0429062 |
| EZR | ezrin | 0.0425105 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0422533 |
| RHOA | ras homolog family member A | 0.0421689 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0418506 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0417432 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0413968 |
| PCBP2 | poly(rC) binding protein 2 | 0.040324 |
| RNF145 | ring finger protein 145 | 0.0402739 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0401607 |
| RPL3 | ribosomal protein L3 | 0.039822 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0393617 |
| MSN | moesin | 0.0383183 |
| FLNB | filamin B, beta | 0.038309 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0381052 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0378022 |
| PGK1 | phosphoglycerate kinase 1 | 0.0371295 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0360996 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0360903 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0352817 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.035232 |
| RACK1 | receptor for activated C kinase 1 | 0.0345035 |
| HMGB2 | high mobility group box 2 | 0.0343174 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0339049 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0337519 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0336072 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0335531 |
| RPL8 | ribosomal protein L8 | 0.0333988 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0333905 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0329341 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0327967 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0327473 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0326837 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0326374 |
| FAM13A | family with sequence similarity 13, member A | 0.031944 |
| AREG | amphiregulin | 0.0318915 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0317968 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0316491 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0311002 |
| VEGFA | vascular endothelial growth factor A | 0.0307878 |
| SRPK2 | SRSF protein kinase 2 | 0.0306783 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0306716 |
| H1-0 | H1.0 linker histone | 0.0306448 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.030596 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0305613 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0305572 |
| MYO10 | myosin X | 0.0303974 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0302062 |
| TMF1 | TATA element modulatory factor 1 | 0.0300765 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0299395 |
| RPS13 | ribosomal protein S13 | 0.0296304 |
| RBM39 | RNA binding motif protein 39 | 0.02958 |
| ERBIN | erbb2 interacting protein | 0.0294252 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0294215 |
| ENAH | enabled homolog (Drosophila) | 0.0293722 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0291142 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0290568 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0290191 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0732393 |
| CCND1 | cyclin D1 | -0.0383433 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0363803 |
| EFNA5 | ephrin-A5 | -0.0311537 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0297647 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0280662 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0260886 |
| FBXO32 | F-box protein 32 | -0.0260175 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0238012 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0229112 |
| NDRG1 | N-myc downstream regulated 1 | -0.0222736 |
| PLSCR1 | phospholipid scramblase 1 | -0.0205272 |
| RPL35A | ribosomal protein L35a | -0.0204342 |
| NAV2 | neuron navigator 2 | -0.0198701 |
| MX2 | MX dynamin-like GTPase 2 | -0.0197621 |
| CSTB | cystatin B (stefin B) | -0.0196352 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0188402 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.018093 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0180539 |
| OCLN | occludin | -0.0177717 |
| DSG2 | desmoglein 2 | -0.0164964 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0160686 |
| TMSB10 | thymosin beta 10 | -0.015658 |
| LMO7 | LIM domain 7 | -0.0145641 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0143266 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0136411 |
| FBXO34 | F-box protein 34 | -0.0136208 |
| PLAU | plasminogen activator, urokinase | -0.0135778 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0135747 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.012943 |
| CAB39 | calcium binding protein 39 | -0.0127479 |
| HMGA1 | high mobility group AT-hook 1 | -0.0126936 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0125759 |
| LAMB3 | laminin, beta 3 | -0.012299 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0122778 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0120333 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0118881 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.011844 |
| IFI44L | interferon-induced protein 44-like | -0.0111703 |
| MX1 | MX dynamin-like GTPase 1 | -0.0111438 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0111154 |
| ARF1 | ADP-ribosylation factor 1 | -0.0110775 |
| CDCP1 | CUB domain containing protein 1 | -0.0110225 |
| SVIL | supervillin | -0.0109732 |
| VGLL3 | vestigial-like family member 3 | -0.0107582 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0107358 |
| NRP1 | neuropilin 1 | -0.010584 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0105694 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0105254 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0103657 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.010353 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0103139 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0101536 |
| S100A10 | S100 calcium binding protein A10 | -0.0101061 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0100385 |
| LOXL2 | lysyl oxidase-like 2 | -0.00976294 |
| ANTXR2 | anthrax toxin receptor 2 | -0.00967171 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.00964576 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.00957576 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00944612 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00943418 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00940498 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.00939881 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.00932894 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00906925 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.00896886 |
| TTC9 | tetratricopeptide repeat domain 9 | -0.00896276 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | -0.00856954 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.00845216 |
| S100A4 | S100 calcium binding protein A4 | -0.00824037 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.00810615 |
| ITGB8 | integrin, beta 8 | -0.00809008 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00795772 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00791174 |
| RAB1B | RAB1B, member RAS oncogene family | -0.0078887 |
| HLA-B | major histocompatibility complex, class I, B | -0.00777572 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.00771237 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00770675 |
| RAI14 | retinoic acid induced 14 | -0.00769584 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00769141 |
| NSD1 | nuclear receptor binding SET domain protein 1 | -0.00767851 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00756141 |
| HMGA2 | high mobility group AT-hook 2 | -0.00753907 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.00751246 |
| DTNA | dystrobrevin, alpha | -0.00749334 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0074605 |
| TMEM62 | transmembrane protein 62 | -0.00744235 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0072706 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.00722499 |
| RBM47 | RNA binding motif protein 47 | -0.00722257 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.00721057 |
| ATXN10 | ataxin 10 | -0.00716925 |
| CTSS | cathepsin S | -0.0070925 |
| TJP2 | tight junction protein 2 | -0.00705934 |
| TMEM117 | transmembrane protein 117 | -0.00702754 |
| PATJ | PATJ crumbs cell polarity complex component | -0.00701607 |
| TUBB | tubulin, beta class I | -0.00700205 |
| IRF9 | interferon regulatory factor 9 | -0.00698176 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.00698139 |
| ITGB4 | integrin, beta 4 | -0.00691254 |
