| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Brivudine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Brivudine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.206499 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.193446 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.126322 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.107989 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.083575 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0819299 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0807101 |
| PKM | pyruvate kinase, muscle | 0.0797693 |
| FRMD4A | FERM domain containing 4A | 0.07483 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0728838 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0725632 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0703223 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0693865 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0689965 |
| HELZ | helicase with zinc finger | 0.0683068 |
| H3-3B | H3.3 histone B | 0.0682804 |
| DSPP | dentin sialophosphoprotein | 0.068004 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0657077 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0656771 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0651238 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0643451 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0629806 |
| MAP1B | microtubule-associated protein 1B | 0.0625295 |
| INHBA | inhibin, beta A | 0.0595841 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0592083 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0554575 |
| STK24 | serine/threonine kinase 24 | 0.0550778 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0537707 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0528935 |
| KIF5B | kinesin family member 5B | 0.050539 |
| SMYD3 | SET and MYND domain containing 3 | 0.0505376 |
| SRPK2 | SRSF protein kinase 2 | 0.0505234 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0499489 |
| ENO1 | enolase 1, (alpha) | 0.0488823 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0474448 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0459667 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0455982 |
| SMAD3 | SMAD family member 3 | 0.0446765 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0438189 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0429233 |
| SBF2 | SET binding factor 2 | 0.0426506 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0403982 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0384619 |
| RPS12 | ribosomal protein S12 | 0.0378262 |
| JMJD1C | jumonji domain containing 1C | 0.037465 |
| RPL5 | ribosomal protein L5 | 0.0372021 |
| ZNF638 | zinc finger protein 638 | 0.0369249 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0365725 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0362914 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.035313 |
| ACTG1 | actin gamma 1 | 0.0351617 |
| SPAG9 | sperm associated antigen 9 | 0.0349951 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0341685 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0332157 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0328737 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0316851 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0315907 |
| CALU | calumenin | 0.0305704 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0303947 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0296578 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0289347 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0288151 |
| ERBIN | erbb2 interacting protein | 0.0282193 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0271131 |
| GOLGB1 | golgin B1 | 0.0263924 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0262641 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0260341 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.025898 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0250148 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0245605 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0243782 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0235583 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.021963 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0216159 |
| DST | dystonin | 0.021592 |
| RASA3 | RAS p21 protein activator 3 | 0.0214088 |
| OGA | O-GlcNAcase | 0.0195775 |
| RAI14 | retinoic acid induced 14 | 0.0190273 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0188186 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0176897 |
| PGK1 | phosphoglycerate kinase 1 | 0.0164141 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.016308 |
| FNIP1 | folliculin interacting protein 1 | 0.0162039 |
| KRT18 | keratin 18, type I | 0.0160213 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0156901 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0147453 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0142977 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00854996 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00850362 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.00825774 |
| MEF2A | myocyte enhancer factor 2A | 0.00807163 |
| SLK | STE20-like kinase | 0.00756017 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00717023 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00622019 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.00615022 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.00606681 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.00585675 |
| ASPH | aspartate beta-hydroxylase | 0.0057881 |
| RPLP1 | ribosomal protein, large, P1 | 0.00502151 |
| RPS6 | ribosomal protein S6 | 0.00478246 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.138383 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.137571 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.133817 |
| EFNA5 | ephrin-A5 | -0.130681 |
| MYO1E | myosin IE | -0.118722 |
| TMSB10 | thymosin beta 10 | -0.109369 |
| MYOF | myoferlin | -0.105104 |
| YAP1 | Yes-associated protein 1 | -0.0891047 |
| HMGA2 | high mobility group AT-hook 2 | -0.0881412 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0878045 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0872523 |
| PTMA | prothymosin, alpha | -0.0840419 |
| RPL15 | ribosomal protein L15 | -0.0838596 |
| PTK2 | protein tyrosine kinase 2 | -0.0834862 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0809612 |
| FHIT | fragile histidine triad | -0.0776979 |
| ANXA2 | annexin A2 | -0.076694 |
| PRKCA | protein kinase C, alpha | -0.0756184 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0754335 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0728477 |
| LAMB3 | laminin, beta 3 | -0.0721089 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.070407 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0686726 |
| LAMA4 | laminin, alpha 4 | -0.0670065 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0669759 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0660452 |
| VIM | vimentin | -0.0652712 |
| NDRG1 | N-myc downstream regulated 1 | -0.0647222 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.058105 |
| PARD3 | par-3 family cell polarity regulator | -0.0574618 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0565932 |
| SLTM | SAFB-like, transcription modulator | -0.0551964 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0547251 |
| PRELID2 | PRELI domain containing 2 | -0.0529648 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.052394 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0492644 |
| RPL37 | ribosomal protein L37 | -0.0487303 |
| LMO7 | LIM domain 7 | -0.0462088 |
| EGR1 | early growth response 1 | -0.0461955 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0460457 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0459053 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0441214 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0436681 |
| CANX | calnexin | -0.0435417 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0427626 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0396608 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0392186 |
| S100A10 | S100 calcium binding protein A10 | -0.0388913 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0382106 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0369794 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.036873 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0353674 |
| PDE10A | phosphodiesterase 10A | -0.03442 |
| ZNF292 | zinc finger protein 292 | -0.0344068 |
| RPS13 | ribosomal protein S13 | -0.0337037 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0323118 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.032002 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0313482 |
| RAD51B | RAD51 paralog B | -0.0311294 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0302573 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0287815 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0281248 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0263628 |
| GOLGA4 | golgin A4 | -0.0261096 |
| RPL12 | ribosomal protein L12 | -0.0256028 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0250401 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0237776 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0231745 |
| LDHA | lactate dehydrogenase A | -0.0230754 |
| CD44 | CD44 molecule (Indian blood group) | -0.0217975 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0217608 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0213538 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0200875 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0199659 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0195371 |
| RPS19 | ribosomal protein S19 | -0.0180279 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0172735 |
| GPC6 | glypican 6 | -0.0168181 |
| FLNB | filamin B, beta | -0.0166338 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.016544 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0160786 |
| ATXN1 | ataxin 1 | -0.0160433 |
| RPL23 | ribosomal protein L23 | -0.0134607 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0132095 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -0.012574 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0118157 |
| S100A6 | S100 calcium binding protein A6 | -0.01162 |
| RUNX1 | runt-related transcription factor 1 | -0.0107584 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0105991 |
| RPL31 | ribosomal protein L31 | -0.00992316 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.00955627 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.00895654 |
| VCL | vinculin | -0.00780043 |
| EGFR | epidermal growth factor receptor | -0.00741556 |
| RPS8 | ribosomal protein S8 | -0.0061166 |
| EHBP1 | EH domain binding protein 1 | -0.00482721 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.00425568 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0042541 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.00408819 |
| DNPEP | aspartyl aminopeptidase | -0.00380682 |
