| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Brivudine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Brivudine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0815371 |
| PEG10 | paternally expressed 10 | 0.0685977 |
| HDAC9 | histone deacetylase 9 | 0.0607491 |
| CALR | calreticulin | 0.0593461 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.057898 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0561366 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0499765 |
| NTM | neurotrimin | 0.0496991 |
| B2M | beta-2-microglobulin | 0.0468913 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.046828 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0456222 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0448498 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0448072 |
| H1-0 | H1.0 linker histone | 0.0447072 |
| ZNF638 | zinc finger protein 638 | 0.0419678 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0409089 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0353003 |
| MYO10 | myosin X | 0.0346142 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0343711 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0337926 |
| RPN2 | ribophorin II | 0.0332194 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0330058 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0325224 |
| MAGT1 | magnesium transporter 1 | 0.0322772 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0321874 |
| PHIP | pleckstrin homology domain interacting protein | 0.0312521 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0307889 |
| RPS8 | ribosomal protein S8 | 0.0304848 |
| FBXO11 | F-box protein 11 | 0.03034 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0302581 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0300828 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0300658 |
| EGFR | epidermal growth factor receptor | 0.0297903 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0295888 |
| FUS | FUS RNA binding protein | 0.028665 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0285587 |
| USP25 | ubiquitin specific peptidase 25 | 0.0285236 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0282718 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0282523 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0279209 |
| CCDC88A | coiled-coil domain containing 88A | 0.0275427 |
| RPL28 | ribosomal protein L28 | 0.0273449 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.026712 |
| RREB1 | ras responsive element binding protein 1 | 0.0259912 |
| POU3F2 | POU class 3 homeobox 2 | 0.0259067 |
| URI1 | URI1, prefoldin-like chaperone | 0.0258446 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0257702 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0256273 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0255966 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.0255848 |
| FMNL2 | formin-like 2 | 0.0255098 |
| DENND4A | DENN/MADD domain containing 4A | 0.0254789 |
| MED13L | mediator complex subunit 13-like | 0.0253264 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0251665 |
| USP32 | ubiquitin specific peptidase 32 | 0.0251415 |
| ASPH | aspartate beta-hydroxylase | 0.0251227 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0250999 |
| RPL13A | ribosomal protein L13a | 0.0250852 |
| MTF2 | metal response element binding transcription factor 2 | 0.0249979 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0249492 |
| PRTG | protogenin | 0.0248907 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0248735 |
| SSH2 | slingshot protein phosphatase 2 | 0.0246888 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0245299 |
| TPR | translocated promoter region, nuclear basket protein | 0.0245113 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0244969 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0244216 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0244047 |
| FAT1 | FAT atypical cadherin 1 | 0.0243816 |
| PHF14 | PHD finger protein 14 | 0.0243257 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0242602 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0242417 |
| RPL37 | ribosomal protein L37 | 0.0242075 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0240253 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0240201 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0239594 |
| FBL | fibrillarin | 0.0239522 |
| BBX | bobby sox homolog (Drosophila) | 0.0239496 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0238087 |
| EFNA5 | ephrin-A5 | 0.0234625 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0233685 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0232717 |
| BRDT | bromodomain, testis-specific | 0.0232243 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0232225 |
| EZR | ezrin | 0.023139 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0230533 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.023012 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0227394 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0226751 |
| OXR1 | oxidation resistance 1 | 0.0226355 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0225964 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0225893 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0224627 |
| SIK3 | SIK family kinase 3 | 0.0224621 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 | 0.0223426 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0222166 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | 0.0222164 |
| DSPP | dentin sialophosphoprotein | 0.0221536 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0220891 |
| RASAL2 | RAS protein activator like 2 | 0.0220857 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.125255 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0912786 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0886184 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0879511 |
| COL3A1 | collagen, type III, alpha 1 | -0.0872135 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0860843 |
| TMSB10 | thymosin beta 10 | -0.0855338 |
| AHNAK | AHNAK nucleoprotein | -0.084199 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0683995 |
| COL11A1 | collagen, type XI, alpha 1 | -0.067747 |
| UBC | ubiquitin C | -0.0620132 |
| THBS1 | thrombospondin 1 | -0.0587411 |
| RPS27A | ribosomal protein S27a | -0.0531842 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0508932 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0507696 |
| EMP1 | epithelial membrane protein 1 | -0.0499121 |
| CADM2 | cell adhesion molecule 2 | -0.0474746 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0465721 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0443007 |
| SRP72 | signal recognition particle 72kDa | -0.0428646 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0421369 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0410287 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0405643 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0397103 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0387582 |
| COL1A2 | collagen, type I, alpha 2 | -0.0386872 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0384869 |
| DMD | dystrophin | -0.0375773 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0366847 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0364843 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0362046 |
| S100A10 | S100 calcium binding protein A10 | -0.0351651 |
| PCBP2 | poly(rC) binding protein 2 | -0.0340007 |
| ITGAV | integrin, alpha V | -0.0339392 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.033834 |
| STAG2 | stromal antigen 2 | -0.0331152 |
| NRG1 | neuregulin 1 | -0.0327486 |
| NEBL | nebulette | -0.0327112 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0313277 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0312945 |
| ANXA2 | annexin A2 | -0.0311875 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0306762 |
| RPS21 | ribosomal protein S21 | -0.0305822 |
| MATR3 | matrin 3 | -0.0305013 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0301694 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0299194 |
| ANK2 | ankyrin 2, neuronal | -0.029758 |
| RTN4 | reticulon 4 | -0.029756 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0296976 |
| RHEB | Ras homolog enriched in brain | -0.0290439 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0290287 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0283916 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0283124 |
| HMGB2 | high mobility group box 2 | -0.0281151 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.028041 |
| SET | SET nuclear proto-oncogene | -0.0274934 |
| TFRC | transferrin receptor | -0.027076 |
| CAPNS1 | calpain, small subunit 1 | -0.0266316 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0264826 |
| PCDH9 | protocadherin 9 | -0.0261942 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | -0.0260136 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0258703 |
| TPM1 | tropomyosin 1 (alpha) | -0.0258292 |
| WDR43 | WD repeat domain 43 | -0.0257002 |
| LRRC4C | leucine rich repeat containing 4C | -0.0255964 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0254233 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.025414 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | -0.0252817 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0252516 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.025163 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0249348 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.02479 |
| FAM168B | family with sequence similarity 168, member B | -0.0245308 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | -0.0243983 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.024298 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.024241 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0242017 |
| SNX6 | sorting nexin 6 | -0.0241427 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | -0.0240728 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0240637 |
| GNAS | GNAS complex locus | -0.0240203 |
| TUT4 | terminal uridylyl transferase 4 | -0.0239481 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0239342 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0239033 |
| CBX3 | chromobox homolog 3 | -0.0238762 |
| NUP155 | nucleoporin 155kDa | -0.0237019 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0236488 |
| SMYD3 | SET and MYND domain containing 3 | -0.0235759 |
| MMP1 | matrix metallopeptidase 1 | -0.0233939 |
| STIP1 | stress-induced phosphoprotein 1 | -0.0232843 |
| GLO1 | glyoxalase I | -0.0231807 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0230403 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0230361 |
| PTMA | prothymosin, alpha | -0.0228951 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0228733 |
| TMSB4X | thymosin beta 4, X-linked | -0.022777 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0226409 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0223106 |
| APP | amyloid beta (A4) precursor protein | -0.0223052 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | -0.0222771 |
